To Study the Socio-Economic Profile of SBM Facilitate Respondents

The present study was conducted in Baghpat district of Uttar Pradesh. India covered with 17.5 per cent of the world population. The condition of, hygiene and sanitation, facility of drinking water was very gigantic since large decades. The irrelevant behavior in order to address this challenge was responsible for the many risks were faced by respondents. Through the study, it was found that maximum respondents 42.00% were found in middle age group (35-50 years), followed by 34.00% in old age group (50 year and above) remaining 24.00% in young age group (up to 35 year).The found majority of respondents 62.00% were male and 38.00%% were female, maximum number of respondents 50.00% belonged to other backward caste followed by 37.00% Schedule caste and the remaining were 13.00% general caste, the majority of respondents 64.00% were found literate and 36.00% respondents were found illiterate. The categories of literacy were found as 32.00%, 24.00%, 6.00% and 2.00% found up to primary, high school, graduated and post graduate respectively.  "Sanitation is more important than independence". Mahatma Gandhi    Cleanliness and sanitation were an integral part of Gandhian way of living. His dream was total sanitation for all. He used to emphasize that cleanliness is the most important for physical wellbeing and a healthy environment

A comparative study of operative dynamic compression plating versus non-operative management in fracture shaft of humerus

Background: Fracture shaft of humerus is among injuries which is commonly seen in clinical practice and frequently seen in polytrauma. Humerus   shaft fractures account for 3% of all orthopedic injuries. Nonoperative treatment had been the mainstay of treatment for fracture shaft of humerus earlier. The association of conservative treatment with some morbidity, complications and prolonged immobilization leads to increase in various operative modalities of management. One of the commonly used operative modality is dynamic compression plating (DCP). In view of above considerations, a study was undertaken at our hospital which aimed to compare non-operative treatment with operative DCP for the management of fracture shaft of humerus. Aims and objectives of this study to compare the results of non-operative versus operative treatment of humerus shaft fracture.Methods: It was a prospective comparative study. Total 40 patients were taken for this study. 20 patients for operative and 20 patients for non-operative. Functional outcome was measured by the DASH scoring. P<0.05 was considered statistically significant. Results: Among the 40 patients 14 had excellent results, 12 had good, 8 had fair and 6 had poor results. Functional outcome scores were better for operative group as compared to non- operative group with p<0.0001.  Conclusions: Dynamic compression plating of humerus is better method than conservative method because it achieves higher union rates

Isozyme variants in two natural populations of Lymnaea luteola

Lymnaea luteola is a fresh water gastropod snail, inhabiting ponds and lakes of different parts of India. Two populations of L. luteola were collected from fresh water ponds of district Varanasi (Uttar Pradesh) and analysed for their isozyme variants of Xanthine dehydrogenase (Xdh) and Aldehyde oxidase (Ao) enzymes loci. Both enzymes were found to be represented by two distinct loci and each locus of an enzyme showed polymorphic appearance. Based on the electrophoretic variant data, level of heterozygosity was computed for each enzyme locus. Our analysis clearly reveals that L. luteola inhabiting in these two ponds have undergone enough genetic differentiation

Unified Singular Protocol Flow for OAuth (USPFO) Ecosystem

OAuth 2.0 is a popular authorization framework that allows third-party clients such as websites and mobile apps to request limited access to a user's account on another application. The specification classifies clients into different types based on their ability to keep client credentials confidential. It also describes different grant types for obtaining access to the protected resources, with the authorization code and implicit grants being the most commonly used. Each client type and associated grant type have their unique security and usability considerations. In this paper, we propose a new approach for OAuth ecosystem that combines different client and grant types into a unified singular protocol flow for OAuth (USPFO), which can be used by both confidential and public clients. This approach aims to reduce the vulnerabilities associated with implementing and configuring different client types and grant types. Additionally, it provides built-in protections against known OAuth 2.0 vulnerabilities such as client impersonation, token (or code) thefts and replay attacks through integrity, authenticity, and audience binding. The proposed USPFO is largely compatible with existing Internet Engineering Task Force (IETF) Proposed Standard Request for Comments (RFCs), OAuth 2.0 extensions and active internet drafts

In Silico Structural and Functional Insights into the Lipoxygenase Enzyme of Legume Cajanus Cajan

Lipoxygenases (LOX) are a family of enzymes known to play a key role in the plant response related to osmotic, drought and high-salinity stress. Plants contain multiple isoforms of the lipoxygenase (LOX) enzyme which differs in terms of its substrate preference, optimal pH, product formation, and stability. Till date, no study has been done to focus on the structural and functional aspect of lipoxygenase enzyme of Cajanus cajan, an important legume crop of Indian sub-continent. The present work revealed that the LOX enzyme of Cajanus cajanis a 96.65 kDa monomeric stable protein. It also contained an iron ion as a ligand in its predicted structure. Ramchandran’s analysis showed the modeled tertiary structure to be a stable one with 91.7% residues in the favoured regions. This study will be helpful to understand the structural aspects of LOX enzyme and would help future studies to enhance the expression of this enzyme in response to major abiotic (mainly salt stress) and biotic stresses

MACROSCOPIC IDENTIFICATION OF CRUDE DRUGS FOR AYURVEDIC FORMULATIONS

There are certain diseases in which western medicines are still lacking cure. It is important to note that western medicine is undoubtedly effective for symptomatic control of these disorders but still lacking cure for potential. Apart from this these drugs are having numerous side effects. Keeping this fact in mind the attention diverts towards our ancient system of medicine i.e Ayurveda for radical cure of these diseases. The demand for plant derived products is increasing day by day. For preparation of any Ayurvedic formulation proper identification of crude drug is extremely necessary. Identification of crude drug involves the morphological or macroscopic details and microscopic parameters. These parameters are necessary for the preparation of accurate and potent formulations. Identification of crude drug is the most important step in development of standards for herbal drugs a lot of adulteration is being done. The major problems affecting the quality of crude drug are adulteration or substitution, degradation due to faulty collections, drying or storage. A well known example is of drug Ashoka which is the stem bark of Saraca indica, the material available in the market is frequently found to be Polyalthia longifolia

Resilient Risk based Adaptive Authentication and Authorization (RAD-AA) Framework

In recent cyber attacks, credential theft has emerged as one of the primary vectors of gaining entry into the system. Once attacker(s) have a foothold in the system, they use various techniques including token manipulation to elevate the privileges and access protected resources. This makes authentication and token based authorization a critical component for a secure and resilient cyber system. In this paper we discuss the design considerations for such a secure and resilient authentication and authorization framework capable of self-adapting based on the risk scores and trust profiles. We compare this design with the existing standards such as OAuth 2.0, OpenID Connect and SAML 2.0. We then study popular threat models such as STRIDE and PASTA and summarize the resilience of the proposed architecture against common and relevant threat vectors. We call this framework as Resilient Risk based Adaptive Authentication and Authorization (RAD-AA). The proposed framework excessively increases the cost for an adversary to launch and sustain any cyber attack and provides much-needed strength to critical infrastructure. We also discuss the machine learning (ML) approach for the adaptive engine to accurately classify transactions and arrive at risk scores

A brief study on zinc oxide based nanosorbents and adsorptive removal of heavy metal ions

The liquid waste streams releases from industrial sectors contain numerous inorganic and organic pollutants. These pollutants may be heavy metals and synthetic dyes. Metal oxide based nanomaterials have been used in the removal of such pollutants from waste water by using adsorption techniques. The adsorption based removal of heavy metals is found good alternative over other conventional methods. ZnO nanoparticle based adsorbents have been utilised in the removal different heavy metal ions from waste water. These adsorbents are generally prepared by the incorporation of organic or inorganic materials with ZnO nanoparticles. In this brief review, we will be discussed about different ZnO based nanomaterials which potentially utilised in treatment of waste water containing heavy metals

Upotreba bezstanične matrice iz ošita bivola pri pupčanoj hernioplastici svinja.

Acellularization of xenogenic biomaterials has been highly desired for implantation without considerable adverse inflammatory and immune responses. Therefore, the present study was undertaken to acellularize the diaphragm of buffalo origin and to evaluate the effi cacy of this prepared acellular diaphragm matrix (ADM) scaffolds for the repair of umbilical hernia in pigs. Buffalo diaphragms were acellularized with different concentrations of sodium deoxycholate over a range of periods. Produced ADM scaffolds were used during umbilical hernioplasty in 12 crossbred Landrace pigs. Harvested serum samples on post-implantation days (0, 15 and 30) were subjected to sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis (PAGE) to observe serum protein distribution pattern. Treatment with 2 % sodium deoxycholate lead to complete acellularization of the bubaline diaphragm at 48 h. Microscopic examination of the detergent treated matrix confirmed complete extraction of stromal cells and orderly arranged collagen fibres. All the hernias repaired with ADM remained sound over a period of 3 months. The serum protein distribution on post-implantation day 15 was found different from day zero and becomes normal on day 30. All the hernias implanted with ADM healed completely without graft rejections. The present study suggested that 2 % sodium deoxycholate can be used for complete acellularization of bubaline diaphragm, and produced ADM may be used safely for umbilical hernioplasty in pigs.Bezstanična struktura ksenogenih biomaterijala smatra se povoljnom jer pri implantaciji ne uzrokuje upalne i imunološke reakcije. U ovom je istraživanju proveden postupak dobivanja bezstanične matrice iz ošita (BMO) bivola koji je zatim bio rabljen kao podloga za obnavljanje tkiva pri operaciji pupčane hernije svinja. Gubitak stanične strukture bivoljih ošita proveden je uz pomoć različitih koncentracija natrijeva deoksikolata, primijenjenih u određenim vremenskim razmacima. Proizvedene bezstanične matrice ošita upotrijebljene su pri pupčanoj hernioplastici kod 12 svinja križanaca landras pasmine. Uzorci seruma, prikupljeni 0., 15. i 30. dana nakon implantacije, bili su podvrgnuti natrijev dodecil sulfat-poliakrilamid gel elektroforezi (SDS-PAGE) s ciljem promatranja razdiobe serumskih proteina. Obrada 2 %-tnim natrijevim deoksikolatom dovela je do potpunog gubitka stanične strukture bivoljeg ošita za 48 sati. Mikroskopskim pregledom matrice obrađene detergentom potvrđeno je potpuno uklanjanje stanica strome te uredno raspoređena kolagena vlakna. Mjesta operacije svih hernija kod kojih je upotrijebljena bezstanična matrica ošita ostala su zdrava tijekom 3 mjeseca. Razdioba serumskih proteina 15 dana nakon implantacije bila je različita u odnosu na početni (0.) dan, a 30. dan nakon implantacije vratila se na normalu. Sve hernije operirane uz upotrebu BMO u potpunosti su zacijelile bez odbacivanja presatka. Pomoću 2 % natrijeva deoksikolata postiže se potpuni gubitak stanične strukture bivoljeg ošita koji se može sigurno primijeniti pri pupčanoj hernioplastici svinja

IDENTIFICATION OF PUM KUTAJA AND STRI KUTAJA MENTIONED IN THE AYURVEDIC LITERATURE

Kutaja is one among the frequently used medicinal plants in Ayurveda. Kutaja is the drug of choice for bleeding piles. Acharya Charak quoted Kutaja tvak as the best Sangrahika dravya. It possess properties like Deepana and Pachana and is useful in the management of diarrhoea. Charak enumerated eighteen yogas of Kutaja with the name Vatsaka in Kalpasthana. In this context he described male and female varieties of Kutaja. Modern experts have also described two varieties of Kutaja i.e., Sveta and Krishna variety. The bark and seeds of Kutaja are used for different medicinal purposes. The seeds of Sveta Kutaja and the seeds which are Tikta, possess better medicinal property. The market sample comprises of seeds of both Tikta and Madhur variety mixed together. Market sample of Kutaja mostly comprises of Madhur seeds. There are three species taken under the name of Kutaja i.e., Holarrhena antidysentrica, Wrightia tomentosa and Wrightia tinctoria. It is a matter of confusion that which one is to be taken as Pum Kutaja and which one as Stri Kutaja. This article is to throw some light on different species taken as Kutaja and decide which species should be taken as Pum Kutaja and which one is to be taken as Stri kutaja