Discussion on the legacy of mega-sporting events / Discussão sobre o legado dos megaeventos esportivos

This study aims to verify the impact that mega-sporting events have had on the host venues' economic, social, public, and political structure since the 2000s. We considered the two major mega-sporting events, i.e., the Summer Olympics and the men's soccer World Cup. From this, we built a Legacy Index (LI) for the host venues, based on economic, environmental, infrastructure, social, and technological variables. The results show that both the Olympic Games and the World Cup can generate legacies, and these can be both positive and negative

Uma Aplicação Didática do Protocolo I2C em Sistemas de Comunicação / A Didactic Application of the I2C Protocol in Communication Systems

A fim de ampliar os conceitos abordados sobre sistemas de comunicação, este trabalho abordará uma aplicação didática do protocolo I2C, utilizando como hardware as placas Arduino e Raspberry Pi 3. Além disso, também serão implementados os métodos de detecção de erros checksum e CRC, bem como uma análise estatística dos resultados obtidos

Lesão renal aguda causada por rabdomiólise decorrente de hipocalemia devido à gastroenterocolite aguda: relato de caso / Acute kidney injury caused by rhabdomyolysis as consequence of hypokalemia due to acute gastroenterocolitis: A case report

A gastroenterocolite aguda cursa com quadros diarreicos, que podem desencadear distúrbios hidroeletrolíticos, como a hipopotassemia, sendo esta uma causa de rabdomiólise, que pode resultar em lesão renal aguda. O objetivo desse artigo é relatar as conexões clínicas e fisiológicas entre hipopotassemia, rabdomiólise e lesão renal aguda em uma paciente apresentando gastroenterocolite aguda. A paciente C.A.G.R, sexo feminino, 54 anos, natural e procedente de Araraquara - SP iniciou com vômitos e diarreia associados à parestesia generalizada, principalmente em membros superiores. Procurou auxílio na Unidade de Pronto Atendimento e foi medicada com antiemético e antidiarreico, sendo encaminhada à Santa Casa de Misericórdia de Araraquara, onde foi detectada hipopotassemia severa, elevação importante de CPK e lesão renal aguda

Myxovirus resistance, osteopontin and suppressor of cytokine signaling 3 polymorphisms predict hepatitis C virus therapy response in an admixed patient population: comparison with IL28B

OBJECTIVES: Suppressor of cytokine signaling 3, myxovirus resistance protein and osteopontin gene polymorphisms may influence the therapeutic response in patients with chronic hepatitis C, and an association with IL28 might increase the power to predict sustained virologic response. Our aims were to evaluate the association between myxovirus resistance protein, osteopontin and suppressor of cytokine signaling 3 gene polymorphisms in combination with IL28B and to assess the therapy response in hepatitis C patients treated with pegylated-interferon plus ribavirin. METHOD: Myxovirus resistance protein, osteopontin, suppressor of cytokine signaling 3 and IL28B polymorphisms were analyzed by PCR-restriction fragment length polymorphism, direct sequencing and real-time PCR. Ancestry was determined using genetic markers. RESULTS: We analyzed 181 individuals, including 52 who were sustained virologic responders. The protective genotype frequencies among the sustained virologic response group were as follows: the G/G suppressor of cytokine signaling 3 (rs4969170) (62.2%); T/T osteopontin (rs2853744) (60%); T/T osteopontin (rs11730582) (64.3%); and the G/T myxovirus resistance protein (rs2071430) genotype (54%). The patients who had ≥3 of the protective genotypes from the myxovirus resistance protein, the suppressor of cytokine signaling 3 and osteopontin had a greater than 90% probability of achieving a sustained response (

O bioma pampa no projeto pedagógico de um curso de licenciatura em ciências da natureza no rio grande do sul

Brazilian ecosystems are a topic that must be present in school curricula. The curriculum is an integral part of formal education, constituting its fundamental function in knowledge systematization, and must be present in basic and higher education. It is essential to analyze the curricula dynamics that constitute the higher education courses for teachers. In consequence, this study investigates an approach of the Pampa Biome, an ecosystem considered neglected, as a possible contextualization and interdisciplinarity strategy for Science Education in the degree course in Natural Sciences at the Federal University of Pampa, Campus Uruguaiana. This is research based on a qualitative case study. The methodology is on the documental analysis of the Pedagogical Project of the respective course, through an analytical matrix composed of questions to which the document must be able to answer. As main results, we found that, despite mentioning the Pampa Biome in the commentaries, the document does not provide a theoretical framework and support that justifies its mentions as thematic in the context in which they are applied. Thus, it is necessary to update the Pedagogical Project and include the Pampa Biome as a contextualization theme for education.Los ecosistemas brasileños son un tema importante, que debe estar presente en los currículos escolares. El currículo es una parte integral de la educación formal, constituyendo su función fundamental en la sistematización del conocimiento lo que exige su presencia en la educación básica y superior. Entendiendo la necesidad de analizar la dinámica de los planes de estudio que conforman los cursos de educación superior para docentes, este estudio se dedicó a investigar el abordaje del Bioma Pampa, un ecosistema considerado descuidado, como posible contextualización y estrategia interdisciplinaria para la Educación Científica en la carrera de Ciencias Naturales de la Universidad Federal de Pampa, Campus Uruguaiana. La investigación se caracteriza por ser un caso de estudio cualitativo, cuyo proceso metodológico se basa en el análisis documental del Proyecto Pedagógico del respectivo curso, a través de una matriz analítica compuesta por preguntas a las que el documento debería dar respuesta. Como principales resultados se encontró que, a pesar de mencionar el Bioma Pampa en los comentarios, el documento no brinda un marco teórico y sustento que justifiquen sus menciones como temáticas en el contexto en el que se aplican. Por ello, es necesario actualizar el Proyecto Pedagógico del Curso e incluir el Bioma Pampa como tema de contextualización para la docencia.Os ecossistemas brasileiros são uma importante temática que deve estar presente nos currículos escolares. O currículo é uma das partes integrantes da educação formal, constituindo sua função fundamental na sistematização dos conhecimentos, devendo estar presentes no ensino básico e superior. Entendendo a necessidade de analisar a dinâmica dos currículos que constituem os cursos superiores formadores de professores, o presente estudo dedicou-se a investigar a abordagem do Bioma Pampa, um ecossistema considerado negligenciado, como uma possível estratégia de contextualização e interdisciplinaridade para o Ensino de Ciências no curso de Licenciatura em Ciências da Natureza da Universidade Federal do Pampa, Campus Uruguaiana. A pesquisa se caracteriza como um estudo de caso, de cunho qualitativo, estando o processo metodológico baseado na análise documental do Projeto Pedagógico do respectivo curso, através de uma matriz analítica composta por perguntas às quais o documento deve ser capaz de responder. Como principais resultados constatou-se que, apesar de mencionar o Bioma Pampa nos ementários, o documento não fornece referencial teórico e aporte que fundamente as suas menções como temática no contexto em que estão aplicadas. Desta forma, faz-se necessária a atualização do Projeto Pedagógico do Curso e a inclusão do Bioma Pampa como temática de contextualização para o ensino

Amyotrophic lateral sclerosis: one or multiple causes?

The Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in the adulthood, and it is characterized by rapid and progressive compromise of the upper and lower motor neurons. The majority of the cases of ALS are classified as sporadic and, until now, a specific cause for these cases still is unknown. To present the different hypotheses on the etiology of ALS. It was carried out a search in the databases: Bireme, Scielo and Pubmed, in the period of 1987 to 2011, using the following keywords: Amyotrophic lateral sclerosis, motor neuron disease, etiology, causes and epidemiology and its similar in Portuguese and Spanish. It did not have consensus as regards the etiology of ALS. Researches demonstrates evidences as regards intoxication by heavy metals, environmental and occupational causes, genetic mutations (superoxide dismutase 1), certain viral infections and the accomplishment of vigorous physical activity for the development of the disease. There is still no consensus regarding the involved factors in the etiology of ALS. In this way, new research about these etiologies are necessary, for a better approach of the patients, promoting preventive programs for the disease and improving the quality of life of the patients

The influence of normative and subjective oral health status on schoolchildren’s happiness

Abstract\ud \ud Background\ud Traditional methods to measure oral health based on clinical standards are limited because they do not consider psychosocial and functional aspects of oral health. It has been recommended that these measures need to be supplemented by data obtained from patients regarding their individual perceptions on oral health-related quality of life (OHRQoL). Happiness is a multidimensional construct comprising both emotional and cognitive domains, and has been defined as “the degree to which an individual judges the overall quality of his or her life as a whole favorably”. It has been associated with several health outcomes, including oral health. The aim of this study was to assess the impact of oral health conditions, oral health-related quality of life (OHRQoL), and socioeconomic factors on the subjective happiness of Brazilian adolescents.\ud \ud \ud Methods\ud A cross-sectional study was conducted in 2012 on a representative sample of 12-year-old schoolchildren in Santa Maria-RS, Brazil. The data were collected through dental examinations and structured interviews. The participants underwent an evaluation aimed at detecting dental caries, traumatic dental injuries, malocclusion, and gingival bleeding. They also completed the Brazilian versions of the Child Perceptions Questionnaire-short form (CPQ11–14 – ISF: 16) and the Subjective Happiness Scale (SHS), which was our outcome variable. Socioeconomic conditions were evaluated through a questionnaire that was completed by the participants’ parents. Poisson regression analysis was used to determine the association between the explanatory variables and the outcome. Moreover, a correlation analysis was performed to determine the relationship between the SHS scores and the overall and domain scores of the CPQ11–14 –ISF: 16.\ud \ud \ud Results\ud A total of 1,134 children were evaluated. Unadjusted analyses showed that happiness was associated with socioeconomic indicators, the use of dental services, clinical status, and scores on the OHRQoL measure. After adjustment, household overcrowding (RR: 0.96; 95% CI: 0.93-0.98), dental caries (RR: 0.98; 95% CI: 0.97-0.99), malocclusion (RR: 0.98; 95% CI: 0.96-0.99), and the severity associated with the CPQ11-14 (RR: 0.95; 95% CI: 0.93-0.97) still showed a significant association with lower levels of the mean SHS score.\ud \ud \ud Conclusions\ud Happiness is influenced by oral conditions, socioeconomic status, and OHRQoL.This project was supported by the Conselho Nacional de Desenvolvimento\ud Científico e Tecnológico (CNPq - processo 477118/2013-5)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP - processo 2014/01924-4

Perfil epidemiológico da hanseníase no período de 2015 a 2018 no município de Goianésia (GO) Perfil epidemiológico da hanseníase em Goianésia, Goiás / Epidemiological profile of leprosy in the period from 2015 to 2018 in the city of Goianésia (GO) Epidemiological profile of leprosy in Goianésia, Goiás

Objetivo: Avaliar o perfil epidemiológico da hanseníase no município de Goianésia, Goiás no período de 2015 a 2018. Métodos: Trata-se de um estudo epidemiológico observacional, retrospectivo em que os dados foram extraídos do Sistema de Informação de Agravos de Notificação (SINAN). Resultados: Foram notificados 102 casos durante o recorde temporal estudado. Observou-se a predominância de casos no sexo masculino, e em indivíduos entre 35 e 49 anos, sendo que o grau zero de incapacidade foi detectado em 70,42% dos pacientes. Maior parte era multibacilar, inerentes às formas clínicas dimorfa e virchowiana. Conclusões: O alto coeficiente de detecção da hanseníase identificado demonstra a condição de área prioritária para o controle da doença. Além disso, o grande número de casos das formas multibacilares encontrado no município alertam ainda mais sobre a necessidade imediata de um efetivo controle

APLICABILIDADE DAS PRÁTICAS INTEGRATIVAS NO SISTEMA ÚNICO DE SAÚDE.

Objective: To discuss the applicability of integrative practices in the single health system through the existing literature. Methods: This is a qualitative integrative literature review. The search for works involved in the research was carried out in the following databases: SCIELO, LILACS, BDENF and MEDLINE, using the descriptors in health sciences: "Comprehensive health care", "Complementary therapies" and "Single health system". The inclusion criteria were: articles published between 2013 and 2023, with free access to full texts, articles in Portuguese, English and Spanish and related to the theme. Exclusion criteria were: duplicate articles, incomplete articles, abstracts, reviews, debates, articles published in event proceedings and unavailable in full. Results: The therapeutic resources that make up ICPs are diverse, and in public health services they are more frequent because they favor lower costs. Conclusion: It can be concluded that integrative practices integrated into PHC have a very satisfactory effect on users' quality of life, and should minimize medication that is often unnecessary.Objetivo: Discutir por meio da literatura existente acerca da aplicabilidade das práticas integrativas no sistema único de saúde. Métodos: Trata-se de uma revisão integrativa da literatura de caráter qualitativo. A busca dos trabalhos envolvidos na pesquisa foi realizada nas seguintes bases de dados: SCIELO, LILACS, BDENF e MEDLINE, a partir dos descritores em ciências da saúde: “Assistência integral à saúde”, “Terapias complementares” e “Sistema único de saúde”. Os critérios de inclusão foram: publicados no período entre 2013 e 2023, cujo acesso ao periódico era livre aos textos completos, artigos em idioma português, inglês e espanhol e relacionados a temática. Critérios de exclusão foram: artigos duplicados, incompletos, resumos, resenhas, debates, artigos publicados em anais de eventos e indisponíveis na íntegra. Resultados: Os recursos terapêuticos que compõe as PICs são diversas, sendo que nos serviços públicos de saúde eles são mais frequentes por favorecerem a diminuição de custos. Conclusão: Conclui-se que as práticas integrativas integradas na APS têm um efeito muito satisfatório no que diz respeito a qualidade de vida dos usuários, devendo minimizar ações medicamentosas que muitas das vezes não são necessárias