164 research outputs found

    Amphibia, Anura, Leptodactylidae, <i>Leptodactylus cupreus</i> Caramaschi, Feio and Sao-Pedro, 2008: Distribution extension

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    We provide the first record of Leptodactylus cupreus out of its type locality, as well the first record of this speciesin the State of Espírito Santo, southeastern Brazil. The record of Leptodactylus cupreus from municipality Santa Teresaextends in approximately 220 km to the northeastern of its geographic distribution and establishes the inferior limit of 800m in its altitudinal distribution in the Serra da Mantiqueira

    Neonatal Apex Resection Triggers Cardiomyocyte Proliferation, Neovascularization and Functional Recovery Despite Local Fibrosis

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    So far, opposing outcomes have been reported following neonatal apex resection in mice, questioning the validity of this injury model to investigate regenerative mechanisms. We performed a systematic evaluation, up to 180 days after surgery, of the pathophysiological events activated upon apex resection. In response to cardiac injury, we observed increased cardiomyocyte proliferation in remote and apex regions, neovascularization, and local fibrosis. In adulthood, resected hearts remain consistently shorter and display permanent fibrotic tissue deposition in the center of the resection plane, indicating limited apex regrowth. However, thickening of the left ventricle wall, explained by an upsurge in cardiomyocyte proliferation during the initial response to injury, compensated cardiomyocyte loss and supported normal systolic function. Thus, apex resection triggers both regenerative and reparative mechanisms, endorsing this injury model for studies aimed at promoting cardiomyocyte proliferation and/or downplaying fibrosis. In this article, Nascimento and colleagues demonstrate that neonatal apex resection stimulates cardiomyocyte proliferation and permanent scarring in the apex. Newly formed cardiomyocytes compensate muscle loss by resection, and resected hearts recover functional competence in adulthood. These findings endorse this model for studies aiming to block cardiac fibrosis and/or favoring CM proliferation

    High velocity seawater air-conditioning with thermal energy storage and its operation with intermittent renewable energies

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    The rapid increase in cooling demand for air-conditioning worldwide brings the need for more efficient cooling solutions based on renewable energy. Seawater air-conditioning (SWAC) can provide base-load cooling services in coastal areas utilizing deep cold seawater. This technology is suggested for inter-tropical regions where demand for cooling is high throughout the year, and it has been implemented in islands with short distances from the coast and the deep sea. This paper proposes adjustments to the conventional design of SWAC plants to reduce implementation risks and costs. The approach is named high velocity SWAC and consists of increasing the excavation depth of the seawater pump station up to 20 m below the sea level, compared to 2 to 5 m in conventional SWAC projects. This allows a twofold increase in the speed of inlet pipeline seawater and cooling load of the plant. The cooling load can be expanded twofold with only 55% capital cost and 83% project costs, compared with the costs of a new system. In addition, this article shows that high velocity SWAC plants with thermal energy storage will have an important role supporting the dissemination of intermittent renewable sources of energy in regions where SWAC is a viable cooling alternative

    Energy crisis in Brazil: Impact of hydropower reservoir level on the river flow

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    Water management strategies can have considerable impacts on the regional climate and hydrology. It is usually the case that the construction and operation of hydropower reduce the river flow downstream due to the increase in evaporation. However, this paper shows that in humid regions, such as in Brazil, the hydropower storage reservoirs contribute to increase the flow of the river. This observation has been tested with historical reservoir levels and river flow data from several dams in Brazil. It was found that the operation of reservoirs in Brazil has a considerable impact on its river flows. The higher the storage level at the beginning of the humid period, the higher the river flow during the wet period. The paper proposes strategies to allow the reservoirs to fill up and to maintain the reservoirs filled in the future, with the intention of increasing hydropower generation and reducing the intermittency of other renewable energy sources

    Associação entre Mycoplasma spp. e ácaros do conduto auditivo de bovinos

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    Esse estudo foi realizado com o objetivo de verificar a associação entre micoplasmas e ácaros (Raillietia auris e R. flechtmanni) no conduto auditivo de bovinos. Foram realizadas lavagens no conduto auditivo externo de 60 bovinos abatidos no Estado do Rio de Janeiro, Brasil. Para a lavagem dos condutos auditivos foi utilizada solução salina tamponada (PBS, pH 7.2) em seringas estéreis de 60mL. Para o isolamento de micoplasmas foram utilizados pools de ácaros por animal, lavados sucessivamente em 1mL de meio Hayflick modificado. Os lavados dos ácaros foram diluídos de 10-1 até 10-5 e repicados em meio Hayflick modificado, sólido e líquido e incubados a 37°C por 48-72 horas em microaerofilia. A identificação das espécies de micoplasmas foi realizada pelo teste da imunoperoxidase indireta (IPI). Verificou-se alta prevalência de ácaros do gênero Raillietia spp. 76,7% (46/60). O parasitismo por ácaros e micoplasmas foi verificado em 40 animais (74,1%), sendo esta associação significativa (p<0,001). Dos ácaros processados para isolamento de micoplasmas, 193 foram fêmeas e 25 machos. A frequência de Mycoplasma em Raillietia spp. foi de 81,2% (177/218) (p<0.001). Das fêmeas identificadas, 52,3% (101/193) foram R. auris e 47,7% (92/193) R. flechtmanni. A frequência de Mycoplasma nas fêmeas de R. auris foi de 75,2% (76/101) e na espécie R. flechtmanni foi de 88% (81/92) (P<0.05). As espécies de micoplasmas tipificadas pela IPI nos ácaros Raillietia auris foram: M. alkalescens 6,9%, M. arginini 3,4%, M. bovirhinis 9,2%, M. conjunctivae 18,4%, M. mycoides mycoides LC 8,0%, M. capricolum 5,7%. Em R. flechtmanni as espécies de micoplasmas identificadas foram: M. alkalescens 12,2%, M. arginini 1,0%, M. bovirhinis 18,9%, M. bovis 2,2%, M. conjunctivae 21,0%, M. mycoides mycoides LC 11,0% e M. capricolum 4,4%. As espécies de micoplasmas identificadas no conduto auditivo externo dos bovinos foram as mesmas presentes nos ácaros R. auris e R. flechtmanni. Os resultados confirmam que o conduto auditivo externo de bovinos é um habitat de Mycoplasma spp., incluindo espécies potencialmente patogênicas para os rebanhos, além dos ácaros R. auris e R. flechtmanni estarem associados com esses molicutes carreando-os em seu organismo
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