29 research outputs found

    PEMBERDAYAAN MASYARAKAT DESA BANGUNCIPTO, KECAMATAN SENTOLO, KABUPATEN KULON PROGO DALAM PROGRAM PENINGKATAN KUALITAS KESEHATAN KELUARGA

    Get PDF
    Kesehatan merupakan hak dasar tiap manusia dan salah satu faktor yang menentukan kualitas sumberdaya manusia. Upaya untuk memelihara dan meningkatkan kualitas kesehatan perlu dilakukan agar terhindar dari bahaya yang merugikan. Permasalahan yang ada di masyarakat Banguncipto terkait dengan masalah kesehatan diantaranya: masih banyaknya lansia kurang sehat, masih terdapat balita kurang gizi, kurangnya pemahaman tentang narkoba, alkohol dan rokok, kurangnya kesadaran masyarakat akan berberapa penyakit mendasar manusia seperti TB, malaria, rematik, dan diabetes militus, serta kurangnya kesadaran dalam menjaga kesehatan dengan memperhatikan rumah yang sehat. Tujuan dari kegiatan ini adalah memberdayakan masyarakat Banguncipto dalam program peningkatan kualitas kesehatan keluarga. Metode pelaksanaan kegiatan KKN meliputi: survey, penyuluhan/pendidikan masyarakat dan pelatihan/praktek. Dampak dari kegiatan ini adalah meningkatkan derajat kesehatan masyarakat yang diukur dengan: 1)tercipta kesadaran masyarakat sasaran tentang pentingnya pola hidup sehat dan kebersihan, 2)peningkatan pengetahuan masyarakat terhadap upaya preventif menekan angka kesakitan, 3)peningkatan pengetahuan masyarakat akan bahaya narkoba dan alkohol bagi kesehatan, 4)masyarakat terampil dalam mengatur pola makan dengan gizi berimbang dan kebersihan lingkungan

    Similarity Check TLC-Bioautography Profile of Ethyl Acetate Extract of 5 Bacteria Isolated from Ficus carica L Rhizosphere

    Get PDF
    Research has been conducted on the 5 isolates of bacteria isolated from the rhizosphere of Ficus carica L as a producer of antibiotics. The previous study showed they have NRPS gene profiles that differ from each other. This study aims to determine the TLC Rf spots having inhibition activity against the growth of Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922. The study was conducted using the 5 bacteria isolates, namely T19, T24, T25, T37 and T41. All isolates were fermented at room temperature for 14 days. Further the each broth culture was filtered and extracted using ethyl acetate. Components in the extract were separated by thin layer chromatography (TLC) with the mobile phase of chloroform-methanol (7: 3), followed by bioautography test against the S. aureus and E. coli to determine the chromatogram spots containing antibiotics. TLC results showed all isolates had different chromatogram profiles. The bioautography results showed that only isolate T25 can produce antibiotics against S. aureus. The antibiotic spot was at Rf 0.9 in the use of chloroform-methanol (7: 3) solvent system

    Conventional and Microwave-Assisted Synthesis of 4’-Bromochalchone Utilizing 4-Bromoacetophenone and Benzaldehyde as Starting Material in Alkaline Condition

    Get PDF
    This study focuses on synthesizing 4’-bromochalcone through conventional and irradiation microwave methods to determine each method's time efficiency and yield. 4-Bromoacetophenone was treated with benzaldehyde in the presence of a base. Conventionally, the reaction mixture was stirred at room temperature. While in the microwave irradiation method, the reaction mixture was irradiated at a power of 140 watts. The compound was identified, including the melting point and physicochemical properties. The structure of the compound was confirmed by infrared, 1H- and 13C-nuclear magnetic resonance, and mass spectroscopy spectral data. The results showed that 4’-bromochalcone had been successfully synthesized using conventional and microwave irradiation methods in a good yield (94.61%±0.6793 and 89.39%±0.6418, consecutively). The structure assignment based on infrared, 1H- and 13C-nuclear magnetic resonance, and mass spectroscopy spectral data revealed that the synthesized product was 4’-bromochalcone. Synthesis of 4’-bromochalchone using microwave irradiation could be done in a shorter time than the conventional method.

    Similarity Check Aktivitas Cairan Kultur Bakteri Penghasil Antibiotik (Isolat P301) terhadap Staphylococcus aureus ATCC 25923 dan Optimasi Waktu Produksi Metabolit Sekunder

    Get PDF
    Isolat P301 adalah bakteri penghasil antibiotik yang diisolasi dari rizosfer tanaman padi. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antibakteri dari cairan kultur isolat P301 terhadap Staphylococcus aureus ATCC 25923 dan mengetahui profil optimasi waktu produksi metabolit sekunder dari isolat P301 sebagai penghasil antibiotik. Aktivitas antibakteri ditetapkan dengan metode sumuran dengan mengukur zona hambat di sekitar sumuran. Penentuan profil optimasi waktu produksi metabolit sekunder yaitu dengan membuat grafik hubungan antara diameter zona hambat dengan waktu inkubasi. Hasil penelitian menunjukkan bahwa cairan kulturisolat P301 mampu menghambat pertumbuhan S. aureus. Berdasarkan uji aktivitas terhadap S. aureus, waktu produksi antibiotik yang optimal adalah setelah diinkubasi minimal selama 11 hari

    RESIDU PESTISIDA PIRETROID PADA BAWANG MERAH DI DESA SRIGADING KECAMATAN SANDEN KABUPATEN BANTUL

    Get PDF
    Pyrethroid pesticide residue in onion from Srigading Village, Sanden District,Bantul Regency has been investigated. The purpose of this study were to analyze,identificate and evaluate pyrethroid pesticide residues in onion. Onion sample wasextracted using homogenizer with acetone solvent. Clean-up was done usingchromatography column using florisil and determination of pesticide residue in thesamples was carried out by gas chromatography apparatus equipped with electroncapture detector (GC-ECD). The result showed that pesticide residues in onion samplein the range level: -cypermethrin (98.8-245.6 ppb) and -cyhalothrin (14.4-120.0ppb). The following pesticides have been detected in some of samples of onion analysed,but they have been detected above the Maximum Residue Limit (MRL)

    RESIDU PESTISIDA ALDRIN DAN DIELDRIN PADA SAMPEL TANAH DAN AIR DI DESA SRIGADING KECAMATAN SANDEN KABUPATEN BANTUL

    Get PDF
    Aldrin and dieldrin pesticide residue in soil and water samples from Srigading Village, Sanden District,Bantul Regency has been investigated. The purpose of this study were to analyze, identificate and evaluatepyrethroid pesticide residues in soil and water samples. Soil sample was extracted using shaker with acetonesolvent. Water samples was extracted using separator funnel with 15% (v/v) dichloromethane/n-hexanesolvent.Clean-up was couducted using chromatography column using florisil and determination of pesticideresidue in the samples was carried out by gas chromatography apparatus equipped with electron capture detector(GC-ECD). The result showed that pesticide residues in soil sample in the range level: aldrin (4,8-64,8 ppb) anddieldrin (not detected-6,0 ppb). In water sample pesticide residues in the range level: aldrin (not detected-1,0 ppb)dan dieldrin (-not detected1,2 ppb). The quality or water sample taken from onion field is laid under the standardof water that has been settled

    UJI AKTIVITAS PENGHAMBATAN POLIMERISASI HEME (1)-N-(2-NITROBENZIL)-1,10- FENANTROLINIUM IODIDA DAN (1)-N-(4-NITROBENZIL)-1,10- FENANTROLINIUM IODIDA SECARA IN VITRO

    Get PDF
    Kemampuan penghambatan polimerisasi heme (1)-N-(2-nitrobenzil)-1,10-fenantrolinium iodida dan (1)-N-(4-nitrobenzil)-1,10-fenantrolinium iodida telah diteliti. Tujuan dilakukan penelitian ini adalah untuk mengetahui kemampuan dari senyawa baru (1)-N-(2-nitrobenzil)-1,10-fenantrolinium iodida dan (1)-N-(4-nitrobenzil)-1,10-fenantrolinium iodida dalam menghambat polimerisasi heme. Penelitian ini menggunakan metode eksperimental secara in vitro. Aktivitas penghambatan polimerisasi heme dilihat berdasarkan nilai IC50 (konsentrasi ekstrak yang mampu menghambat polimerisasi heme hingga 50%). Nilai IC50 diperoleh menggunakan analisis probit. Aktivitas penghambatan polimerisasi heme ditunjukkan dengan nilai IC50 Nilai IC50 senyawa (1)-N-(2-nitrobenzil)-1,10-fenantrolinium iodida tidak dapat ditentukan. Nilai IC50 senyawa (1)-N-(4-nitrobenzil)-1,10-fenantrolinium iodida dan klorokuin secara berturut–turut adalah 0,571±0,071; 25,498±1,876 mg/mL. Hasil penelitian menunjukkan bahwa senyawa (1)-N-(4-nitrobenzil)-1,10-fenantrolinium iodida memiliki kemampuan penghambatan polimerisasi heme yang lebih baik jika dibandingkan dengan klorokuin sedangkan senyawa (1)-N-(2-nitrobenzil)-1,10-fenantrolinium iodida tidak memiliki aktivitas penghambatan polimerisasi heme
    corecore