Biomechanical Study Using the Finite Element Method of Internal Fixation in Pauwels Type III Vertical Femoral Neck Fractures

Background: Several factors are known to influence osseous union of femoral neck fractures. Numerous clinical studies have reported different results, hence with different recommendations regarding treatment of Pauwels III fractures: femoral neck fractures with a more vertically oriented fracture line. The current study aimed to analyze biomechanically whether this fracture poses a higher risk of nonunion. Objectives: To analyze the influence of one designated factor, authors believe that a computerized fracture model, using a finite element Finite Element Method (FEM), may be essential to negate the influence of other factors. The current study aimed to investigate a single factor, i.e. orientation of the fracture line toward a horizontal line, represented by Pauwels classification. It was hypothesized that a model with a vertically oriented fracture line maintaining parity of all other related factors has a higher stress at the fracture site, which would delay fracture healing. This result can be applicable to other types of pinning. Patients and Methods: The finite element models were constructed from computed tomography data of the femur. Three fracture models, treated with pinning, were constructed based on Pauwels classification: Type I, 30° between the fracture line and a horizontal line; Type II, 50°; and Type III, 70°. All other factors were matched between the models. The Von Mises stress and principal stress distribution were examined along with the fracture line in each model. Results: The peak Von Mises stresses at the medial femoral neck of the fracture site were 35, 50 and 130 MPa in Pauwels type I, II, and III fractures, respectively. Additionally, the peak Von Mises stresses along with the fracture site at the lateral femoral neck were 140, 16, and 8 MPa in Pauwels type I, II, and III fractures, respectively. The principal stress on the medial femoral neck in Pauwels type III fracture was identified as a traction stress, whereas the principal stress on the lateral femoral neck in Pauwels type I fracture was a compression stress. Conclusions: The most relevant finding was that hook pinning in Pauwels type III fracture may result in delayed union or nonunion due to significantly increased stress of a traction force at the fracture site that works to displace the fracture. However, in a Pauwels type I fracture, increased compression stress contributes to stabilize it. Surgeons are recommended not to treat Pauwels type III femoral neck fractures by pinning

Impacts of seasonal transitions of enso on atmospheric river activity over east Asia

Atmospheric rivers (ARs), which are narrow water vapor transport bands over the mid-latitudes, often have great socio-economic impacts over East Asia. Although summertime AR activity over East Asia is strongly induced by preceding-winter El Niño development, the extent to which seasonal transitions of El Niño–Southern Oscillation (ENSO) from winter to summer affect the AR activity remains unclear. Here, we examine the relationship between the seasonal transitions of ENSO and the summertime AR activity over East Asia using an atmospheric reanalysis and high-resolution atmospheric general circulation model (AGCM) ensemble simulations. A rapid transition from preceding-winter El Niño to summertime La Niña results in more AR occurrence over northern East Asia via the northward expansion of an anomalous low-level anticyclone over the western North Pacific compared with sustained or decayed El Niño cases. The northward expansion of the anticyclone is consistent with a steady response of the atmosphere to the anomalous condensation heating over the Maritime Continent and equatorial Pacific. Meridional positions of the extratropical AR occurrence and circulation anomalies are different between the reanalysis and AGCM simulations, which is possibly contributed by a limited sample size and/or AGCM biases and suggests that the seasonal prediction of AR-related natural disaster risk over East Asia on a regional scale remains a challenge

Universality of electron accumulation at wurtzite c- and a-plane and zinc-blende InN surfaces

Electron accumulation is found to occur at the surface of wurtzite (112¯0), (0001), and (0001¯) and zinc-blende (001) InN using x-ray photoemission spectroscopy. The accumulation is shown to be a universal feature of InN surfaces. This is due to the low Г-point conduction band minimum lying significantly below the charge neutrality level

Atmospheric rivers over the Northwestern Pacific: Climatology and interannual variability

Atmospheric rivers (ARs), conduits of intense water vapor transport in the midlatitudes, are critically important for water resources and heavy rainfall events over the west coast of North America, Europe, and Africa. ARs are also frequently observed over the northwestern Pacific (NWP) during boreal summer but have not been studied comprehensively. Here the climatology, seasonal variation, interannual variability, and predictability of NWP ARs (NWPARs) are examined by using a large ensemble, high-resolution atmospheric general circulation model (AGCM) simulation and a global atmospheric reanalysis. The AGCM captures general characteristics of climatology and variability compared to the reanalysis, suggesting a strong sea surface temperature (SST) effect on NWPARs. The summertime NWPAR occurrences are tightly related to El Niño-Southern Oscillation (ENSO) in the preceding winter through Indo-western Pacific Ocean capacitor (IPOC) effects. An enhanced East Asian summer monsoon and a low-level anticyclonic anomaly over the tropical western North Pacific in the post-El Niño summer reinforce low-level water vapor transport from the tropics with increased occurrence of NWPARs. The strong coupling with ENSO and IPOC indicates a high predictability of anomalous summertime NWPAR activity

Household mortgage demand: a study of the UK, Australia and Japan

Households combine their personal savings and mortgage debt to finance their home purchases. In developed countries, mortgage debt is the largest debt on a household’s balance sheet and in these countries, the mortgage penetration rates are high. For the stability of the mortgage market and thereby the money market in an economy, it is important to understand households' mortgage demand decisions and riskiness of these borrowers. There are differences in mortgage systems among countries, which play an important role in determining the mortgage decisions that households make. These differences arise from the availability of types of mortgage instrument (adjustable versus fixed rate mortgages), length of fixed period for a fixed rate mortgage contracts, conditions of prepayment, tax treatment, lenders’ constraints related to repayment, loan to value ratio, foreclosure and personal bankruptcy laws etc. These differences impact borrowers' choice of mortgage contract and mortgage demand. This paper analyses the mortgage demand behaviour of households in the UK, Australia and Japan. Specific questions that have been asked relate to the factors that determine household mortgage demand, housing demand and loan to value ratio. Though the homeownership is a preferred tenure and the mortgages are 'recourse' loans, housing markets in these three countries operate in different mortgage market institutional structure. Results indicate that income elasticity of mortgage demand differ despite income elasticity of housing demand being similar. Mortgage institutions that pose constraints for borrowers also determine the extent of mortgage demand. Other factors such as demography, economic conditions have also played an important role in determining mortgage and housing demand

Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency

Biallelic variants in the EYS gene are a major cause of autosomal recessive inherited retinal disease (IRD), with a high prevalence in the Asian population. The purpose of this study was to identify pathogenic EYS variants, to determine the clinical/genetic spectrum of EYS-associated retinal disease (EYS-RD), and to discover disease-associated variants with relatively high allele frequency (1%-10%) in a nationwide Japanese cohort. Sixty-six affected subjects from 61 families with biallelic or multiple pathogenic/disease-associated EYS variants were ascertained by whole-exome sequencing. Three phenotype groups were identified in EYS-RD: retinitis pigmentosa (RP; 85.94%), cone-rod dystrophy (CORD; 10.94%), and Leber congenital amaurosis (LCA; 3.12%). Twenty-six pathogenic/disease-associated EYS variants were identified, including seven novel variants. The two most prevalent variants, p.(Gly843Glu) and p.(Thr2465Ser) were found in 26 and twelve families (42.6%, 19.7%), respectively, for which the allele frequency (AF) in the Japanese population was 2.2% and 3.0%, respectively. These results expand the phenotypic and genotypic spectrum of EYS-RD, accounting for a high proportion of EYS-RD both in autosomal recessive RP (23.4%) and autosomal recessive CORD (9.9%) in the Japanese population. The presence of EYS variants with relatively high AF highlights the importance of considering the pathogenicity of non-rare variants in relatively prevalent Mendelian disorders

A Young Brown Dwarf Companion to DH Tauri

We present the detection of a young brown dwarf companion DH Tau B associated with the classical T Tauri star DH Tau. Near-infrared coronagraphic observations with CIAO on the Subaru Telescope have revealed DH Tau B with H = \~15 mag located at 2.3" (330 AU) away from the primary DH Tau A. Comparing its position with a Hubble Space Telescope archive image, we confirmed that DH Tau A and B share the common proper motion, suggesting that they are physically associated with each other. The near-infrared color of DH Tau B is consistent with those of young stellar objects. The near-infrared spectra of DH Tau B show deep water absorption bands, a strong K I absorption line, and a moderate Na I absorption line. We derived its effective temperature and surface gravity of Teff = 2700 -- 2800 K and log g = 4.0--4.5, respectively, by comparing the observed spectra with synthesized spectra of low-mass objects. The location of DH Tau B on the HR diagram gives its mass of 30 -- 50 M_Jupiter.Comment: 10 pages, 14 figures, 1 table, accepted for publication in Ap

Two-Dimensional Vanadium Carbide (MXene) as Positive Electrode for Sodium-Ion Capacitors

Ion capacitors store energy through intercalation of cations into an electrode at a faster rate than in batteries and within a larger potential window. These devices reach a higher energy density compared to electrochemical double layer capacitor. Li-ion capacitors are already produced commercially, but the development of Na-ion capacitors is hindered by lack of materials that would allow fast intercalation of Na-ions. Here we investigated the electrochemical behavior of 2D vanadium carbide, V2C, from the MXene family. We investigated the mechanism of Na intercalation by XRD and achieved capacitance of ∼100 F/g at 0.2 mV/s. We assembled a full cell with hard carbon as negative electrode, a known anode material for Na ion batteries, and achieved capacity of 50 mAh/g with a maximum cell voltage of 3.5 V