Feminine and Feminist Sensibilities in the Select Plays of Vijay Tendulkar

The present research is an immense endeavour to explore feminine and feminist sensibilities in the select plays of Vijay Tendulkar. It attempts to find out the place and position of women besides the root causes of gender inequality in the male dominated social structure. It is a minute study of weak and strong female characters who lose their identity and freedom for the sake of their male counterparts and for so called social conventions. Furthermore, it shows a sordid picture of patriarchal social structure, it's hallow moral standards, the gloomy facet of middle class life in the context of contemporary India where women undergo a series of sufferings and age-old tortures. It truly underlines the worst and obscure sensibilities of women in the light of several past centuries. Also it projects women's efforts in order to fulfill their desire for uplifting from the burdens of customs and norms. This study endeavours to analyse the psychological problems, dilemmas, conflicts and a series of sufferings and tortures of women at various levels in the light of select plays. It also concerns with women's striving for survival with respect and honour, their demand of freedom, dignity, equal rights and the perfection

A comparative study of efficacy and safety of flupirtine versus piroxicamin patients with low back pain

Background: Low back pain is a common musculoskeletal symptom caused by a variety of disorders that affect the lumbar spine. The most frustrating aspect in the treatment of low back pain is that there is “no magic bullets”. The objective of the study was to compare the efficacy and safety of flupirtine versus piroxicam in patients with back pain.Methods: This was prospective, open labeled, randomized, comparative clinical study conducted by the Departments Orthopedics and Pharmacology, BMC&H, Chitradurga. Study was conducted on 60 patients of either sex, aged above 18 years with low back pain. Assessments were done for Finger-to-Floor Distance (FFD), lumbar pain, Lasegue’s sign, tenderness of vertebral muscles, pain & sensory disturbance in lower limbs and response to therapy for efficacy. Parametric data was analyzed by t-test and proportions were compared using Chi-square test.Results: 74 patients were randomized to 2 groups of 37 each. Group I patients received flupirtine maleate 100 mg twice daily and Group II patients received piroxicam 20 mg twice daily for 14 days. 30 patients in each group completed the study and were analysed. On intergroup comparison, there was no statistical difference (p>0.05) in the efficacy parameters of finger-to-floor distance (FFD), lumbar pain, Lasegue’s sign, tenderness of vertebral muscles, sensory disturbance in lower limbs, VAS scores & global assessment of response to therapy. 13.3% in flupirtine group and 16.6% in piroxicam group reported adverse events.  Conclusions: Both flupiritine and piroxicam were equally effective but flupirtine was better tolerated than piroxicam.

FUNDAMENTAL ANALYSIS -A STUDY OF SELECTED STOCKS IN TELECOM SECTOR

ABSTRACT Fundamental analysis is a logical and systematic approach t

Micropropagation and conservation of selected endangered anticancer medicinal plants from the Western Ghats of India

Globally, cancer is a constant battle which severely affects the human population. The major limitations of the anticancer drugs are the deleterious side effects on the quality of life. Plants play a vital role in curing many diseases with minimal or no side effects. Phytocompounds derived from various medicinal plants serve as the best source of drugs to treat cancer. The global demand for phytomedicines is mostly reached by the medicinal herbs from the tropical nations of the world even though many plant species are threatened with extinction. India is one of the mega diverse countries of the world due to its ecological habitats, latitudinal variation, and diverse climatic range. Western Ghats of India is one of the most important depositories of endemic herbs. It is found along the stretch of south western part of India and constitutes rain forest with more than 4000 diverse medicinal plant species. In recent times, many of these therapeutically valued herbs have become endangered and are being included under the red-listed plant category in this region. Due to a sharp rise in the demand for plant-based products, this rich collection is diminishing at an alarming rate that eventually triggered dangerous to biodiversity. Thus, conservation of the endangered medicinal plants has become a matter of importance. The conservation by using only in situ approaches may not be sufficient enough to safeguard such a huge bio-resource of endangered medicinal plants. Hence, the use of biotechnological methods would be vital to complement the ex vitro protection programs and help to reestablish endangered plant species. In this backdrop, the key tools of biotechnology that could assist plant conservation were developed in terms of in vitro regeneration, seed banking, DNA storage, pollen storage, germplasm storage, gene bank (field gene banking), tissue bank, and cryopreservation. In this chapter, an attempt has been made to critically review major endangered medicinal plants that possess anticancer compounds and their conservation aspects by integrating various biotechnological tool

Genomic profiling using array comparative genomic hybridization define distinct subtypes of diffuse large b-cell lymphoma: a review of the literature

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin Lymphoma comprising of greater than 30% of adult non-Hodgkin Lymphomas. DLBCL represents a diverse set of lymphomas, defined as diffuse proliferation of large B lymphoid cells. Numerous cytogenetic studies including karyotypes and fluorescent in situ hybridization (FISH), as well as morphological, biological, clinical, microarray and sequencing technologies have attempted to categorize DLBCL into morphological variants, molecular and immunophenotypic subgroups, as well as distinct disease entities. Despite such efforts, most lymphoma remains undistinguishable and falls into DLBCL, not otherwise specified (DLBCL-NOS). The advent of microarray-based studies (chromosome, RNA, gene expression, etc) has provided a plethora of high-resolution data that could potentially facilitate the finer classification of DLBCL. This review covers the microarray data currently published for DLBCL. We will focus on these types of data; 1) array based CGH; 2) classical CGH; and 3) gene expression profiling studies. The aims of this review were three-fold: (1) to catalog chromosome loci that are present in at least 20% or more of distinct DLBCL subtypes; a detailed list of gains and losses for different subtypes was generated in a table form to illustrate specific chromosome loci affected in selected subtypes; (2) to determine common and distinct copy number alterations among the different subtypes and based on this information, characteristic and similar chromosome loci for the different subtypes were depicted in two separate chromosome ideograms; and, (3) to list re-classified subtypes and those that remained indistinguishable after review of the microarray data. To the best of our knowledge, this is the first effort to compile and review available literatures on microarray analysis data and their practical utility in classifying DLBCL subtypes. Although conventional cytogenetic methods such as Karyotypes and FISH have played a major role in classification schemes of lymphomas, better classification models are clearly needed to further understanding the biology, disease outcome and therapeutic management of DLBCL. In summary, microarray data reviewed here can provide better subtype specific classifications models for DLBCL

ANALYSIS OF TOOL WEAR IN TURNING OPERATION OF ALUMINIUM

The present work is the representation of the research work carried out by the authors to analyze tool wear in turning operation of Aluminium.. The objectives of the research was to specify specific speed, feed, depth of cut which results least tool wear while working with aluminium part & HSS tool. Also to find out the maximum & minimum wear occurring on HSS tool at different cutting speeds. &nbsp

LITERATURE REVIEW ON TOOL WEAR IN TURNING OPERATION OF ALUMINIUM

The present work is a literature review of the existing works carried out by the researchers to find out the directions of current research work. The objectives of the research is to specify specific speed, feed, depth of cut which results least tool wear while working with aluminium part & HSS tool. Also to find out the maximum & minimum wear occurring on HSS tool at different cutting speeds