Nano TiO2 as an efficient and reusable heterogeneous catalyst for the synthesis of 5-substituted 1H-tetrazoles

Nano TiO2 is an effective heterogeneous catalyst for the [2+3] cycloaddition of sodium azide with nitriles to afford 5-substituted 1H-tetrazoles in good yields. This method has the advantages of high yields, simple methodology and easy work-up. The catalyst is recovered and reused for several cycles with consistent activity. Keywords: 5-substituted 1H-tetrazole, [2+3] cycloaddition, nano TiO2, heterogeneous catalys

Aortic atresia with normally developed left ventricle in a young adult

Congenital aortic valve atresia is usually part of a developmental anomaly usually called ‘hypoplastic left-heart syndrome’. To the best of our knowledge, most reported cases of aortic atresia have been associated with hypoplasia of the ascending aorta, of the left ventricle, and of the mitral valve. We report a patient presenting with aortic atresia with a ventricular septal defect and a normally sized left ventricle. (Cardiol J 2011; 18, 3: 304–306

The relationship between emotional intelligence and addiction potential tendency pre-university students

Background and aims: Unfavorable emotional growth in adults may lead to addiction. This study investigated the relationship between emotional intelligence and students’ potential talent pertaining to addiction. Methods: This study is a descriptive analytical study. All male students of pre-universities in Shahrekord city participated in this study One hundred and twelve participnts were chosen based on the stage cluster sampling. In order to collect data emotional intelligence questionnaire and addictive potential survey (APS) were used. Data were analyzed based on Pearson and regression correlation. Results: The results Showed that there is a negative significant relationship among the emotional intelligence (P<0.05, r=-0.37), emotional save order (P<0.01 r=-0.63, P<0.01 r=-0.60) and emotional usability (P<0.01 r=-0.51, P<0.01 r=-0.49) in students resident in city and in rural area respectively and addiction vulnerability. Emotional intelligence and emotional save order components have the potential to predict the addiction tendency (P<0.01). Conclusion: Lack of emotional intelligence is one of the major factors that affect drug using tendency in students. Therefore, training is necessary for students

The effect of some flavonoids on paraoxonase-1 activity

زمینه و هدف: پاراکسوناز-1 آنزیم وابسته به کلسیم می باشد که با HDL باند می گردد و با داشتن قابلیت جلوگیری از اکسیداسیون LDL نقش مهمی در پیشگیری از اترواسکلروزیس ایفا می کند. به نظر می رسد که آنتی اکسیدان های مختلف مثل فلاونوئیدها بر میزان فعالیت آنزیم پاراکسوناز موثر می باشند. این مطالعه با هدف بررسی اثر برخی از فلاونوئیدها بر میزان فعالیت سرمی آنزیم پاراکسوناز انجام شده است. روش بررسی: در این مطالعه تجربی، ابتدا تعداد 45 عدد موش صحرایی از نژاد ویستار به 9 گروه 5 تایی تقسیم شدند. به گروه 1 به عنوان گروه های شاهد روزانه 1 میلی لیتر محلول آب و اتانول 25 داده شد. به گروه های 2 تا 5 مقدار 5/7 میلی گرم و گروه های 6 تا 9 مقدار 15 میلی گرم از یکی از فلاونوییدهای کوئرستین، میریستین، گالانژین و کامپفرول به ازای هر کیلوگرم وزن بدن به علاوه 1 میلی لیتر اتانول 25 خورانده شد. میانگین تغییرات فعالیت آنزیم بین گروه ها در اثر مداخلات انجام شده در بین گروه ها مقایسه گردید. یافته ها: تفاوت میانگین تغییرات فعالیت آنزیم PON-1 قبل و بعد از تیمار بین همه گروه ها در هر دو دوز 5/7 و 15 میلی گرم به ازای کیلوگرم وزن بدن معنی دار بود (

O efeito do uso a curto prazo da suplementação com Coenzima Q10 nas características físicas e fisiológicas selecionadas de jovens lutadores de elite do sexo masculino

Aim: The aim of the present study was to determine the effect of short-term use of Coenzyme Q10 supplementation on selected physical and physiological characteristics of young male elite wrestlers. &nbsp;Materials and methods: The present study is a quasi-experimental human model which was performed using 20 elite wrestlers young men with an average age of 1 ± 5.18 years, weight 1 ± 35.83 kg, height 8/0 ± 75.1 cm and BMI2 ± 67.26 , subjects were randomly divided into drug and placebo groups, first measured using RAST test (anaerobic performance indices) and Cooper test (aerobic power test), curl up test (local abdominal muscle endurance), Press up test and Chin up (upper body endurance test), then, after six weeks of training, the above tests were performed. The collected data were analyzed using SPSS 21 software. Normalization of groups was first performed by Kolmogorov-Smirnov test and confirmation of homogeneity of variances by Levon's test. Correlated t-test was used to investigate intra-group changes and independent t-test and significance level (P≤0.05) were used to examine inter-group changes. Findings: The results of dependent group t2 test showed a significant difference (P≤0.05) in increasing the amount of changes in the experimental group Aerobic power (6.51 change rate), Maximum power (2.61 change rate), Average power (2.60), Minimum power (2.76 change rate), Fatigue Index (0.46 change rate), Curl up (7.2% Change rate) And Press up (7.7 change rate) in the post-test compared to the pre-test. But there was no significant difference (P≥0.05) in the amount of variables expressed in the control group before and after the Chin up test. Conclusion: The results of this study show that the Q10 supplement can enhance some of the physiological and physiological characteristics of young elite wrestlers.Objetivo: O objetivo do presente estudo foi determinar o efeito do uso a curto prazo da suplementação com Coenzima Q10 nas características físicas e fisiológicas selecionadas de jovens lutadores de elite do sexo masculino. Materiais e métodos: O presente estudo é um modelo humano quase experimental, realizado com 20 jovens lutadores de elite, com idade média de 1 ± 5,18 anos, peso 1 ± 35,83 kg, altura 8/0 ± 75,1 cm e IMC 2 ± 67,26. os indivíduos foram divididos aleatoriamente em grupos de drogas e placebo, medidos pela primeira vez usando o teste RAST (índices de desempenho anaeróbico) e o teste de Cooper (teste de potência aeróbica), teste de enrolamento (resistência local do músculo abdominal), teste de pressão e Chin up, depois de seis semanas de treinamento, os testes acima foram realizados. Os resultados do teste do grupo dependente t2 mostraram uma diferença significativa no aumento da quantidade de alterações no grupo experimental Potência aeróbica (taxa de variação de 6,51), Potência máxima (taxa de variação de 2,61), Potência média (2,60), Potência mínima (taxa de variação de 2,76), índice de fadiga (taxa de variação de 0,46), curvatura (taxa de variação de 7,2%) e pressione (taxa de variação de 7,7%) no pós-teste em comparação com o pré-teste. Conclusão: Os resultados deste estudo mostram que o suplemento Q10 pode melhorar algumas das características fisicas e fisiológicas dos jovens lutadores de elite

Congenital Prothrombin Deficiency

Congenital prothrombin deficiency is an extremely rare hemorrhagic disorder with estimated prevalence of 1 per 2,000,000 in the general population. Since the disorder is an autosomal recessive disorder, the disorder is more frequent in areas with high rate of consanguinity. Clinical manifestations of disorder are highly variable ranging from mild bleeding episodes to severe life-threatening hemorrhages. The disorder can be diagnosed based on routine and specific tests. No specific factor II concentrate is available, but patients can receive fresh frozen plasma and prothrombin complex concentrate (PCC). Traditionally patients with prothrombin deficiency receive on-demand therapy, but secondary prophylaxis can be used for those patients with high risk of severe life-threatening bleeding. With timely diagnosis and appropriate management of disorder, the quality of life in these patients can significantly improve.   Keywords: Prothrombin deficiency, Clinical manifestations, Diagnosis, Treatmen

Designing an entrepreneurship and production curriculum model for high school students

Today, countries around the world attach special importance to "entrepreneurship" as a vital factor of stability and economic growth. Entrepreneurship is one of the main factors in creating economic value and an effective tool to reduce unemployment. Entrepreneurship education and training in developed countries is a significant part of the education programs of schools, universities, organizations and institutions. The task of secondary education is to prepare young people to choose the paths of life and to shape these paths in order to accept responsibilities in the future. Therefore, the present study has tried to collect information from various documents and sources based on the evaluation of the current curriculum from the perspective of relevant groups (specialists, teachers and students) to design the optimal model Entrepreneurship and Production curriculum (EPC) based on the main elements of the curriculum (objectives, content, learning activities and evaluation). In addition, in order to validate the designed model, it was provided to the curriculum specialists and educational staff, and finally, it presented the designed model along with suggestions and solutions. This research is applied from the perspective of purpose and is of evaluation type and the method of conducting it is field research. The statistical population of the study includes curriculum specialists in the field of entrepreneurship, all teachers working to teach entrepreneurship and production and all students studying in the second year of high school in Ahvaz city in the academic year 2020-2021. Sampling of specialists by purposive sampling method by selecting 14 people as a sample and in the group of teachers by simple random method and by selecting 89 teachers and in the group of students using Cochran's formula by stratified random sampling method, and it was done by selecting 300 people. Data collection tool was a researcher-made questionnaire that was redesigned using semi-structured interviews and descriptive statistics, and inferential statistics (Chi-square) were used to analyze the data. Statistically, there is a difference between the opinions of the study groups in the element of objectives, content, learning activities and evaluation of the current EPC of the second secondary school. Therefore, based on the results of evaluation and semi-structured interviews with experts and teachers, the proposed model has been designed.Hoy en día, países de todo el mundo prestan especial atención al "espíritu empresarial" como factor vital de estabilidad y crecimiento económico. Por tanto, el presente estudio tiene como objetivo evaluar el currículo actual desde la perspectiva de grupos relevantes (especialistas, docentes y estudiantes) para diseñar el modelo curricular óptimo de Emprendimiento y Producción (EPC) basado en los principales elementos del currículo (objetivos, contenidos, aprendizaje). actividades y evaluación). Además, para validar el modelo diseñado, se entregó a los especialistas curriculares y al personal docente. La población estadística del estudio incluye especialistas en currículo, maestros que enseñan espíritu empresarial y todos los estudiantes que cursan el segundo año de la escuela secundaria en la ciudad de Ahvaz en el año académico 2020-2021. El muestreo de especialistas (14 especialistas) se realizó mediante el método de muestreo intencional, los profesores (89 profesores) mediante el método aleatorio simple y los estudiantes (300 estudiantes) mediante la fórmula de Cochran y el método de muestreo aleatorio estratificado. La herramienta de recolección de datos fue un cuestionario elaborado por investigadores que fue rediseñado mediante entrevistas semiestructuradas y estadística descriptiva, y se utilizó estadística inferencial (Chi-cuadrado) para analizar los datos. Los resultados mostraron que hubo una diferencia entre los grupos de estudio en los elementos principales. Por tanto, a partir de los resultados de la evaluación y entrevistas semiestructuradas con expertos y profesores, se diseñó el modelo propuesto. Según esto, las categorías más básicas son las metas, que pueden facilitar otras acciones y pasos del plan de estudios

Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model

Introduction: The aim of the present study was to evaluate the biocompatibility of two modified formulations of Portland cement (PC) mixed with either titanium oxide or both titanium oxide and calcium chloride. Methods and Materials: Polyethylene tubes were filled with modified PCs or Angelus MTA as the control; the tubes were then implanted in 28 Wistar rats subcutaneously. One tube was left empty as a negative control in each rat. Histologic samples were taken after 7, 15, 30 and 60 days. Sections were assessed histologically for inflammatory responses and presence of fibrous capsule and granulation tissue formation. Data were analyzed using the Fisher’s exact and Kruskal-Wallis tests. Result: PC mixed with titanium oxide showed the highest mean scores of inflammation compared with others. There was no statistically significant difference in the mean inflammatory grades between all groups in each of the understudy time intervals. Conclusion: The results showed favorable biocompatibility of these modified PC mixed with calcium chloride and titanium oxide.Keywords: Biocompatibility; Mineral Trioxide Aggregate; Portland Cemen