EMODnet physics: towards an European impulsive noise register

EMODnet Physics, one of the European Marine Observation and Data network thematic portals, which is is currently providing access physical parameters of the oceans, has recently started working on water noise with the aim of making available more operational data (in terms of parameters and format that are close to MSFD I.11 requirements), offer a single European entry point to impulsive noise registries (MSFD I.11.1) and work on (regional) sound maps.Peer Reviewe

EMODnet: your gateway to marine data in Europe

Peer Reviewe

New approach to underwater technologies for innovative, low-cost ocean observation (nautilos): operational field primary capture system

The large variety of platforms and sensors globally deployed and available, allows access to a conspicuous quantity of data and variables with heterogeneous formats and scales. In the last decades governments and the scientific world have encouraged standardizations and best practices for data collection, elaboration and distribution. Several initiatives had led the bases for globally shared practices and quality indexes. This paper aims at giving a state of the art concerning the existing best practices and quality indices of the most important platforms, initiatives and projects for the scope of NAUTILOS - New Approach to Underwater Technologies for Innovative, Low-cost Ocean observation - H2020 project (www.nautilosh-2020.eu; ct. 101000825)info:eu-repo/semantics/publishedVersio

EMODnet physics and river runoff data management

Rivers runoff exert a strong influence in their neighbouring coastal area in several ways, modifying the water stratification, introducing significant fluctuations in circulation patterns and modulating the impact of upwelling events. This paper presents data management methods and standards to make harmonised river data available and accessible.Peer Reviewe

EMODnet physics and river runoff data management

Rivers runoff exert a strong influence in their neighbouring coastal area in several ways, modifying the water stratification, introducing significant fluctuations in circulation patterns and modulating the impact of upwelling events. This paper presents data management methods and standards to make harmonised river data available and accessible.Peer Reviewe

Enhancing social well-being and economic prosperity by reinforcing the effectiveness of protection and restoration management in mediterranean MPAs

Enhancing scientific understanding and providing practical guidance for safeguarding and rejuvenating the EU’s Mediterranean Blue Natural Capital employing an Ecosystem-Based Management (EBM) approach.Peer Reviewe

Thiazolidin-4-one formation. Mechanistic and synthetic aspects of the reaction of imines and mercaptoacetic acid under microwave and conventional heating

Microwave irradiation of a mixture of benzylidene-anilines and mercaptoacetic acid in benzene gives 1,3-thiazolidin-4- ones in very high yield (65–90%), whereas the same reaction performed through using the conventional method, at refluxtemperature, requires a much longer time and gives a much lower yield (25–69%). This difference seems to be due to someintermediates and by-products formed during the conventional reaction. On the basis of 1H NMR studies, two differentmechanisms, acting in benzene and in DMF, respectively, have been hypothesized for the thiazolidin-4-one system formation

Antitumor Agents. 5. Synthesis, Structure-Activity Relationships, and Biological Evaluation of Dimethyl-5H-pyridophenoxazin-5-ones, Tetrahydro-5H-benzopyridophenoxazin-5-ones, and 5H-Benzopyridophenoxazin-5-ones with Potent Antiproliferative Activity

New antiproliferative compounds, dimethyl-5H-pyrido[3,2-a]phenoxazin-5-ones (1-6), tetrahydro-5Hbenzopyrido[ 2,3-j]phenoxazin-5-ones (7-9), and 5H-benzopyrido[3,2-a]phenoxazin-5-ones (10-12) were synthesized and evaluated against representative human neoplastic cell lines. Dimethyl derivatives 1-6 were more active against carcinoma than leukemia cell lines. The tetrahydrobenzo derivatives 7-9 were scarcely active, whereas the corresponding benzo derivatives 10-12 showed notable cytotoxicity against a majority of the tested cell lines. Molecular modeling studies indicated that the high potency of 10 and 11, the most cytotoxic compounds of the whole series, could be due to the position of the condensed benzene ring, which favors ð-ð stacking interactions with purine and pyrimidine bases in the DNA active site. Biological studies suggested that 10-12 have no effect on human topoisomerases I and II and that they induce arrest at the G2/M phase