Properties of lubricants for refrigeration system with the low GWP refrigerants

For the prevention of global warming, various low GWP refrigerants (R1234yf, R1234ze, R448A, R449A, R452A, R452B, R454B etc.) were proposed as the alternative to HFC refrigerants for refrigeration system. In this report, the combinations of the low GWP refrigerants and lubricants were evaluated. The evaluation items are physical properties (miscibility, solubility, viscosity, and electric property)and thermal stability

Sunspot Observations by Hisako Koyama: 1945-1996

The sunspot record is the only observational tracer of solar activity that provides a fundamental, multi-century reference. Its homogeneity has been largely maintained with a succession of long-duration visual observers. In this paper, we examine observations of one of the primary reference sunspot observers, Hisako Koyama. By consulting original archives of the National Museum of Nature and Science of Japan (hereafter, NMNS), we retrace the main steps of her solar-observing career, from 1945 to 1996. We also present the reconstruction of a full digital database of her sunspot observations at the NMNS, with her original drawings and logbooks. Here, we extend the availability of her observational data from 1947-1984 to 1945-1996. Comparisons with the international sunspot number (version 2) and with the group sunspot number series show a good global stability of Koyama's observations, with only temporary fluctuations over the main interval 1947-1982. Identifying drawings made by alternate observers throughout the series, we find that a single downward baseline shift in the record coincides with the partial contribution of replacement observers mostly after 1983. We determine the correction factor to bring the second part (1983-1996) to the same scale with Koyama's main interval (1947-1982). We find a downward jump by 9% after 1983, which then remains stable until 1996. Overall, the high quality of Koyama's observations with her life-long dedication leaves a lasting legacy of this exceptional personal achievement. With this comprehensive recovery, we now make the totality of this legacy directly accessible and exploitable for future research.Comment: Main text 31 pages, references 6 pages, 13 figures, 3 tabes, accepted for publication in Monthly Notices of the Royal Astronomical Society, 202

Copper-Catalyzed Regioselective Aminothiolation of Aromatic and Aliphatic Alkenes with N-Fluorobenzenesulfonimide and Thiols through Three-Component Radical Coupling

Copper-catalyzed regioselective aminothiolation of terminal and internal alkenes with N-fluorobenzenesulfonimide and thiols has been developed. The three-component reaction is promoted by the addition of dimethyl sulfide. In addition to aromatic alkenes, aliphatic alkenes are subjected to the reaction, affording various aminothiolation adducts as single regioisomers. The radical process is proposed by preliminary mechanistic studies, involving radical trap and radical clock experiments

DNC/HNC Ratio of Massive Clumps in Early Evolutionary Stages of High-Mass Star Formation

We have observed the HN13C J=1-0 and DNC J=1-0 lines toward 18 massive clumps, including infrared dark clouds (IRDCs) and high-mass protostellar objects (HMPOs), by using the Nobeyama Radio Observatory 45 m telescope. We have found that the HN13C emission is stronger than the DNC emission toward all the observed sources. The averaged DNC/HNC ratio is indeed lower toward the observed high-mass sources (0.009\pm0.005) than toward the low-mass starless and star-forming cores (0.06). The kinetic temperature derived from the NH3 (J, K) = (1, 1) and (2, 2) line intensities is higher toward the observed high-mass sources than toward the low-mass cores. However the DNC/HNC ratio of some IRDCs involving the Spitzer 24 {\mu}m sources is found to be lower than that of HMPOs, although the kinetic temperature of the IRDCs is lower than that of the HMPOs. This implies that the DNC/HNC ratio does not depend only on the current kinetic temperature. With the aid of chemical model simulations, we discuss how the DNC/HNC ratio decreases after the birth of protostars. We suggest that the DNC/HNC ratio in star-forming cores depends on the physical conditions and history in their starless-core phase, such as its duration time and the gas kinetic temperature.Comment: 27 pages, 4 figures, accepted to Ap

MEDICAL TREATMENT OF UNRUPTURED CEREBRAL ANEURYSMS

Background: Currently there are no pharmacological therapies for patients with unruptured cerebral aneurysms. Elsewhere we showed that the mineralocorticoid receptor antagonist eplerenone prevented the formation of cerebral aneurysms in our ovariectomized hypertensive aneurysm rat model. The current pilot study evaluated whether it can be used to prevent the growth and rupture of cerebral aneurysms in hypertensive patients. Methods: Between August 2011 and May 2014, we enrolled 82 patients with 90 aneurysms in an open-label uncontrolled clinical trial. All provided prior informed consent for inclusion in this study, and all were treated with eplerenone (25-100 mg/d). The primary end points of our study were the rupture and enlargement of the cerebral aneurysms. Results: Of the 82 patients, 80 (88 unruptured aneurysms) were followed for a mean of 21.3 months (153.4 aneurysm-years); 12 patients (15.0%) permanently discontinued taking the drug. One month after the start of eplerenone administration and throughout the follow-up period, eplerenone kept the blood pressure within the normal range. Most notably, no aneurysms smaller than 9 mm ruptured or enlarged. However, of 2 large thrombosed aneurysms, 1 enlarged and the other ruptured. The overall annual rupture rate was .65%; it was 13.16% for aneurysms larger than 10 mm; the overall annual rate for reaching the primary end points was 1.30%. Conclusion: Our observations suggest that eplerenone may help to prevent the growth and rupture of unruptured cerebral aneurysms smaller than 9 mm. To assess its potential long-term clinical benefits, large clinical trials are needed

カノウセイ セキツイエン ニタイスル キョウシカ ツイカンバン ヘルニア テキシュツジュツ PED ノ ジュツゴ セイセキ

The number of pyogenic spinal infections has been increasing in the past few decades. The main reason for increasing of cases is increasing of immunosuppressed patients, such as diabetes mellitus, neoplasmic disease, collagen disease or chronic renal failure. Some immunosuppressed patients with pyogenic spinal infection were resistant to an antibiotic treatment and they were not able to undergo major spinal surgery due to their poor general conditions. Percutaneous endoscopic lumbar discectomy（PED）is performed under local anesthesia and requires an８mm skin incision. PED is the least invasive disc surgery procedure, especially for poor general condition patients with pyogenic lumbar spondylitis. The purpose of this study is to evaluate effect of PED procedure for pyogenic spondylitis. Four male and one female pyogenic spondylitis underwent PED surgery under local anesthesia. The mean age was６７．０±12.9（４７－７７）. The number of complications for ４ patients is as follows；２malignant tumor,３hypertension,１diabetes mellitus,１liver cirrhosis and １ Parkinson disease. Causative bacteria were identified in the blood or the biopsy specimens. We performed the debridement of the infected disc and of the partial endplate in the lumbar spine. Approximately３０００－ ５０００milliliter saline was used for irrigation. The mean day from diagnosis to surgery was １２．６ days（１１－１５ days）. Post operative courses of all patients were successful. The mean day to turn CRP negative after surgery is５２．２ days（３８－１１０ days）. There was no complication and no additional surgery after debridement using PED procedure. The PED procedure is superior to other treatments in terms of directly debridement and lavage the infected sites. The most advantage of PED procedure is able to directly observe on clear vision under endoscope. Moreover, PED surgery can be safely performed under local anesthesia and requires the least invasion. This procedure can be applied to the poor general condition’s patients

Instant estimation of rice yield using ground-based RGB images and its potential applicability to UAV

Rice (Oryza sativa L.) is one of the most important cereals, which provides 20% of the world’s food energy. However, its productivity is poorly assessed especially in the global South. Here, we provide a first study to perform a deep learning-based approach for instantaneously estimating rice yield using RGB images. During ripening stage and at harvest, over 22,000 digital images were captured vertically downwards over the rice canopy from a distance of 0.8 to 0.9m at 4,820 harvesting plots having the yield of 0.1 to 16.1 t ha-1 across six countries in Africa and Japan. A convolutional neural network (CNN) applied to these data at harvest predicted 68% variation in yield with a relative root mean square error (rRMSE) of 0.22. Even when the resolution of images was reduced (from 0.2 to 3.2cm pixel-1 of ground sampling distance), the model could predict 57% variation in yield, implying that this approach can be scaled by use of unmanned aerial vehicles. Our work offers low-cost, hands-on, and rapid approach for high throughput phenotyping, and can lead to impact assessment of productivity-enhancing interventions, detection of fields where these are needed to sustainably increase crop production

Deep learning enables instant and versatile estimation of rice yield using ground-based RGB images

"AIの目"によるイネ収穫量の簡単・迅速推定. 京都大学プレスリリース. 2023-07-21.Rice (Oryza sativa L.) is one of the most important cereals, which provides 20% of the world’s food energy. However, its productivity is poorly assessed especially in the global South. Here, we provide a first study to perform a deep-learning-based approach for instantaneously estimating rice yield using red-green-blue images. During ripening stage and at harvest, over 22, 000 digital images were captured vertically downward over the rice canopy from a distance of 0.8 to 0.9 m at 4, 820 harvesting plots having the yield of 0.1 to 16.1 t·ha⁻¹ across 6 countries in Africa and Japan. A convolutional neural network applied to these data at harvest predicted 68% variation in yield with a relative root mean square error of 0.22. The developed model successfully detected genotypic difference and impact of agronomic interventions on yield in the independent dataset. The model also demonstrated robustness against the images acquired at different shooting angles up to 30° from right angle, diverse light environments, and shooting date during late ripening stage. Even when the resolution of images was reduced (from 0.2 to 3.2 cm·pixel−1 of ground sampling distance), the model could predict 57% variation in yield, implying that this approach can be scaled by the use of unmanned aerial vehicles. Our work offers low-cost, hands-on, and rapid approach for high-throughput phenotyping and can lead to impact assessment of productivity-enhancing interventions, detection of fields where these are needed to sustainably increase crop production, and yield forecast at several weeks before harvesting

Functional tooth number and mortality

Aim: Previous studies on the association between intraoral conditions and mortality in community-dwelling older individuals reported that fewer present teeth (PT) are significant risk factors for mortality. However, how the number of PT relative to the number of functional teeth (FT), including both present and rehabilitated teeth, influences mortality has not been investigated fully. This study examined the impact of the number of FT on mortality among community-dwelling Japanese older adults. Methods: This study was a retrospective, observational and population-based follow-up study, which examined 1188 older individuals who participated in an annual geriatric health examination from 2009 to 2015. The average follow-up period was 1697.0 ± 774.5 days. The primary outcome was all-cause mortality at follow-up. The numbers of PT and FT of each participant were counted during an oral examination. In addition, demographics, clinical variables, blood nutrient markers, physical functions and perceived masticatory function were measured. Results: Kaplan–Meier analysis, followed by a log-rank test, revealed that fewer PT (P < 0.001) and FT (P = 0.002) were significantly associated with a reduced survival rate. Cox's proportional hazard analysis indicated that the number of FT, but not the number of PT, was a significant independent mortality risk factor after adjusting for demographics, clinical variables, nutrient markers and physical functioning (P = 0.036, hazard ratio: 2.089). Conclusions: Current results suggest that the number of FT more strongly predicts all-cause mortality than the number of PT among community-dwelling older adults. Further studies are necessary to consider the confounding of socioeconomic status and disability status