10 research outputs found

    Understanding 'non-genetic' inheritance : insights from molecular-evolutionary crosstalk

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    The idea for this paper was initially proposed by I.A.-K. and was further developed by all authors in a workshop generously funded by grant No 789240 from the European Research Council (ERC) to F.J.W. S.E.S. acknowledges support from Wesleyan University and The John Templeton Foundation.Understanding the evolutionary and ecological roles of 'non-genetic' inheritance (NGI) is daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights from molecular and evolutionary biology perspectives to identify three general features of 'non-genetic' inheritance systems: (i) they are functionally interdependent with, rather than separate from, DNA sequence; (ii) precise mechanisms vary phylogenetically and operationally; and (iii) epigenetic elements are probabilistic, interactive regulatory factors and not deterministic 'epialleles' with defined genomic locations and effects. We discuss each of these features and offer recommendations for future empirical and theoretical research that implements a unifying inherited gene regulation (IGR) approach to studies of 'non-genetic' inheritance.Publisher PDFPeer reviewe

    Biochemical composition and nutritional value of Streptocephalus simplex as live feed in ornamental fish culture

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    A feed trail was conducted to evaluate the efficiency of Streptocephalus simplex as a live feed in freshwater ornamental fish culture. The efficiency of live feed was compared with that of artificial/pellet diet to determine the growth rate biochemical parameters and carotenoid concentration of Carassius auratus for a period of 45 days. As a result the proximate composition on the S. simplex indicates that they are rich in protein, lipids, essential amino acids and fatty acids. Availability of these growth factors was perfectly reflected on the successful growth rate of C. auratus. Moreover, presence of carotenoids viz., astaxanthin (36.4 ± 2.4), canthaxanthin (23.6 ± 1.7), and β-carotene (1.7 ± 0.6) has improved the intensity of the skin color of commercially important ornamental fish C. auratus after feeding with S. simplex

    Dengue

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    Lecture 49 ISBN e-book : 9781615045754International audienc

    Cryptic Host Defense Peptides: Multifaceted Activity and Prospects for Medicinal Chemistry

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    Dengue

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