Migration and animal husbandry: Competing or complementary livelihood strategies. Evidence from Kyrgyzstan

Animal husbandry and labour migration are important livelihood strategies for a large proportion of the rural population in developing countries. Up to now, the two strategies have usually been studied by looking at either one or the other; their interlinkages have rarely been examined. Based on a case study in rural Kyrgyzstan, the aim of this paper is to explore the links between animal husbandry and labour migration. Results show that for most rural households, livestock is crucial yet not sufficient to make a living. Therefore, many people diversify their income sources by migrating to work elsewhere. This generates cash for daily expenses and the acquisition of new livestock, but also leads to an absence of workforce in households. Yet since remittances usually exceed the expenses for hiring additional workforce, most people consider migration profitable. From a socio-economic point of view, migration and animal husbandry can thus be considered important complementary livelihood strategies for the rural Kyrgyz population, at least for the time being. In the long term, however, the failure of young migrants to return to rural places and their settlement in urban areas might also cause remittance dependency and lead to an increasing lack of qualified labour. From an environmental point of view, the investment of remittances into animal husbandry poses challenges to sustainable pasture management. Increasing livestock numbers in rural areas raise pressure on pasture resources. Since most people consider animal husbandry their main future prospect while continuing to use pastures in a fairly unsustainable way, this may further exacerbate the over-utilization of pastures in future

The suppression of hidden order and onset of ferromagnetism in URu2Si2 via Re substitution

Substitution of Re for Ru in the heavy fermion compound URu2Si2 suppresses the hidden order transition and gives rise to ferromagnetism at higher concentrations. The hidden order transition of URu(2-x)Re(x)Si2, tracked via specific heat and electrical resistivity measurements, decreases in temperature and broadens, and is no longer observed for x>0.1. A critical scaling analysis of the bulk magnetization indicates that the ferromagnetic ordering temperature and ordered moment are suppressed continuously towards zero at a critical concentration of x = 0.15, accompanied by the additional suppression of the critical exponents gamma and (delta-1) towards zero. This unusual trend appears to reflect the underlying interplay between Kondo and ferromagnetic interactions, and perhaps the proximity of the hidden order phase.Comment: 8 pgs, 5 figs, ICM 2009; please refer to Phys. Rev. Lett. 103, 076404 (2009), arXiv:0908.1809 for details on magnetic scaling and phase diagram (reference added to this version

Harnessing the ‘hustle’: struggle, solidarities and narratives of work in Nairobi and beyond

In a workshop entitled ‘Harnessing the Hustle’, held at the British Institute in Eastern Africa (BIEA) in April 2017, a group of academic researchers and community activists came together to discuss a concept that resonated across ethnographic findings and everyday life alike: hustling. For many of us working in Nairobi for years, we considered the real ‘experts in the room’ to be our Kenyan interlocutors, many of whom have become research collaborators and friends. Most of them lived and worked in different corners of the city, but they had the following in common: they were born and raised in Nairobi, and they self-identified as ‘hustlers’ and with the practice of ‘hustling’ in their everyday life. Alongside our friends and collaborators, we reflected on each paper’s empirical context in which hustling featured as a narrative and set of urban practices and positionings. Throughout the afternoon it became clear that the theoretical registers of hustling merited attention. Hustling was not only a street vernacular; it had also become a way for youth to conceptualize their own struggles, politics and agency. Ironically, the BIEA, which hosted our discussion, is located in the leafy ex-colonial neighbourhood of Kileleshwa. Seemingly removed from Nairobi’s familiar sounds and sensory bombardment, we discussed the need to decolonize ethnographic research and theory, guided by our Kenyan colleagues, artists, collaborators and critics in the workshop

Dissolved organic matter characteristics of deciduous and coniferous forests with variable management: different at the source, aligned in the soil

This dataset contains the data to the article: "Dissolved organic matter characteristics of deciduous and coniferous forests with variable management: different at the source, aligned in the soil" published in BiogeosciencesDFG/108154260/Elementkreisläufe in Grünland- und Waldökosystemen der Biodiversitätsexploratorien in Abhängigkeit von Landnutzungsintensität und damit verknüpfter Biodiversität/BECycle

Effect of eyelid muscle action and rubbing on telemetrically obtained intraocular pressure in patients with glaucoma with an IOP sensor implant

Background Patients with glaucoma on topical glaucoma medication are often affected by dry eye symptoms and thus likely to rub or squeeze their eyelids. Here, we telemetrically measure peak intraocular pressure (IOP) during eyelid manoeuvres and eyelid rubbing. Methods Eleven patients with primary open-angle glaucoma (POAG) previously implanted with a telemetric IOP sensor (Eyemate-IO) were instructed to look straight ahead for 1 min as a baseline measurement. Next, 6 repeats of blinking on instruction with 10 s intervals in between were performed. In addition, 5 repeats of eyelid closure (n=9), eyelid squeezing and eyelid rubbing (n=7) were performed with 15 s intervals in between. IOP was recorded via an external antenna placed around the study eye. Average peak IOP increases from baseline were analysed and tested against zero (no change) with one-sample t-tests. Results For eyelid rubbing, the average peak increment IOP increase (mean +/- SEM) was 59.1 +/- 9.6 mm Hg (p</p

Effect of eyelid muscle action and rubbing on telemetrically obtained intraocular pressure in patients with glaucoma with an IOP sensor implant

Background Patients with glaucoma on topical glaucoma medication are often affected by dry eye symptoms and thus likely to rub or squeeze their eyelids. Here, we telemetrically measure peak intraocular pressure (IOP) during eyelid manoeuvres and eyelid rubbing. Methods Eleven patients with primary open-angle glaucoma (POAG) previously implanted with a telemetric IOP sensor (Eyemate-IO) were instructed to look straight ahead for 1 min as a baseline measurement. Next, 6 repeats of blinking on instruction with 10 s intervals in between were performed. In addition, 5 repeats of eyelid closure (n=9), eyelid squeezing and eyelid rubbing (n=7) were performed with 15 s intervals in between. IOP was recorded via an external antenna placed around the study eye. Average peak IOP increases from baseline were analysed and tested against zero (no change) with one-sample t-tests. Results For eyelid rubbing, the average peak increment IOP increase (mean +/- SEM) was 59.1 +/- 9.6 mm Hg (p</p

Implanted Microsensor Continuous IOP Telemetry Suggests Gaze and Eyelid Closure Effects on IOP-A Preliminary Study

PurposeTo explore the effect of gaze direction and eyelid closure on intraocular pressure (IOP).MethodsEleven patients with primary open-angle glaucoma previously implanted with a telemetric IOP sensor were instructed to view eight equally-spaced fixation targets each at three eccentricities (10°, 20°, and 25°). Nine patients also performed eyelid closure. IOP was recorded via an external antenna placed around the study eye. Differences of mean IOP between consecutive gaze positions were calculated. Furthermore, the effect of eyelid closure on gaze-dependent IOP was assessed.ResultsThe maximum IOP increase was observed at 25° superior gaze (mean ± SD: 4.4 ± 4.9 mm&nbsp;Hg) and maximum decrease at 25° inferonasal gaze (-1.6 ± 0.8 mm&nbsp;Hg). There was a significant interaction between gaze direction and eccentricity (P = 0.003). Post-hoc tests confirmed significant decreases inferonasally for all eccentricities (mean ± SEM: 10°: -0.7 ± 0.2, P = 0.007; 20°: -1.1 ± 0.2, P = 0.006; and 25°: -1.6 ± 0.2, P = 0.006). Eight of 11 eyes showed significant IOP differences between superior and inferonasal gaze at 25°. IOP decreased during eyelid closure, which was significantly lower than downgaze at 25° (mean ± SEM: -2.1 ± 0.3 mm&nbsp;Hg vs. -0.7 ± 0.2 mm&nbsp;Hg, P = 0.014).ConclusionsOur data suggest that IOP varies reproducibly with gaze direction, albeit with patient variability. IOP generally increased in upgaze but decreased in inferonasal gaze and on eyelid closure. Future studies should investigate the patient variability and IOP dynamics

The regulatory and transcriptional landscape associated with carbon utilization in a filamentous fungus.

Filamentous fungi, such as Neurospora crassa, are very efficient in deconstructing plant biomass by the secretion of an arsenal of plant cell wall-degrading enzymes, by remodeling metabolism to accommodate production of secreted enzymes, and by enabling transport and intracellular utilization of plant biomass components. Although a number of enzymes and transcriptional regulators involved in plant biomass utilization have been identified, how filamentous fungi sense and integrate nutritional information encoded in the plant cell wall into a regulatory hierarchy for optimal utilization of complex carbon sources is not understood. Here, we performed transcriptional profiling of N. crassa on 40 different carbon sources, including plant biomass, to provide data on how fungi sense simple to complex carbohydrates. From these data, we identified regulatory factors in N. crassa and characterized one (PDR-2) associated with pectin utilization and one with pectin/hemicellulose utilization (ARA-1). Using in vitro DNA affinity purification sequencing (DAP-seq), we identified direct targets of transcription factors involved in regulating genes encoding plant cell wall-degrading enzymes. In particular, our data clarified the role of the transcription factor VIB-1 in the regulation of genes encoding plant cell wall-degrading enzymes and nutrient scavenging and revealed a major role of the carbon catabolite repressor CRE-1 in regulating the expression of major facilitator transporter genes. These data contribute to a more complete understanding of cross talk between transcription factors and their target genes, which are involved in regulating nutrient sensing and plant biomass utilization on a global level

From regional pulse vaccination to global disease eradication: insights from a mathematical model of Poliomyelitis

Mass-vaccination campaigns are an important strategy in the global fight against poliomyelitis and measles. The large-scale logistics required for these mass immunisation campaigns magnifies the need for research into the effectiveness and optimal deployment of pulse vaccination. In order to better understand this control strategy, we propose a mathematical model accounting for the disease dynamics in connected regions, incorporating seasonality, environmental reservoirs and independent periodic pulse vaccination schedules in each region. The effective reproduction number, $R_e$, is defined and proved to be a global threshold for persistence of the disease. Analytical and numerical calculations show the importance of synchronising the pulse vaccinations in connected regions and the timing of the pulses with respect to the pathogen circulation seasonality. Our results indicate that it may be crucial for mass-vaccination programs, such as national immunisation days, to be synchronised across different regions. In addition, simulations show that a migration imbalance can increase $R_e$ and alter how pulse vaccination should be optimally distributed among the patches, similar to results found with constant-rate vaccination. Furthermore, contrary to the case of constant-rate vaccination, the fraction of environmental transmission affects the value of $R_e$ when pulse vaccination is present.Comment: Added section 6.1, made other revisions, changed titl