15,065 research outputs found

    Different Methods of Forming Cold Fronts in Non-Merging Clusters

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    Sharp edges in X-ray surface brightness with continuous gas pressure called cold fronts have been often found in relaxed galaxy clusters such as Abell 496. Models that explain cold fronts as surviving cores of head-on subcluster mergers do not work well for these clusters and competing models involving gas sloshing have been recently proposed. Here, we test some concrete predictions of these models in a combined analysis of density, temperature, metal abundances and abundance ratios in a deep Chandra exposure of Abell 496. We confirm that the chemical discontinuities found in this cluster are not consistent with a core merger remnant scenario. However, we find chemical gradients across a spiral "arm" discovered at 73 kpc north of the cluster center and coincident with the sharp edge of the main cold front in the cluster. Despite the overall SN Ia iron mass fraction dominance found within the cooling radius of this cluster, the metal enrichment along the arm, determined from silicon and iron abundances, is consistent with a lower SN Ia iron mass fraction (51% +- 14%) than that measured in the surrounding regions (85% +- 14%). The "arm" is also significantly colder than the surroundings by 0.5-1.6 keV. The arm extends from a boxy colder region surrounding the center of the cluster, where two other cold fronts are found. This cold arm is a prediction of current high resolution numerical simulations as a result of an off-center encounter with a less massive pure dark matter halo and we suggest that the cold fronts in A496 provide the first clear corroboration of such model, where the closest encounter happened ~ 0.5 Gyr ago. We also argue for a possible candidate dark matter halo responsible for the cold fronts in the outskirts of A496.Comment: 11 ApJ pages, 1 Table, 16 Figures, accepted for publication in the Astrophysical Journal. For full version with all hi-res figures click on http://www.astro.lsa.umich.edu/~rdupke/a496sub.pd

    Site within N-Methyl-D-aspartate receptor pore modulates channel gating

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    N-methyl-d-aspartate-type glutamate receptors (NMDARs) are ligand-gated ion channels activated by coagonists glutamate and glycine. NMDARs play a critical role in synaptic plasticity and excitotoxicity, largely because of their high calcium permeability and slow deactivation and desensitization kinetics. NR1 is an obligate subunit in all NMDAR complexes, where it combines with NR2A, 2B, 2C, and/or 2D. NR1 binds glycine, and residue Asn598 in the re-entrant membrane loop M2 largely determines NMDAR calcium permeability. In contrast, NR2 subunits bind glutamate and contain regions that regulate receptor desensitization and deactivation. Here, we report that mutations of NR1(Asn598) in combination with wild-type NR2A, expressed in human embryonic kidney 293 cells, exhibit altered glycine-independent desensitization. In the absence of extracellular calcium, substitution of Arg for Asn598 (NR1R) slowed desensitization by 2- to 3-fold compared with wild-type NR1/NR2A, and glutamate-evoked peak current EC50 and deactivation rate were also affected. Replacement of Asn by Gln (NR1Q) produced two distinct rates of calcium- and glycine-independent desensitization. Moreover, in the presence of extracellular calcium, the voltage-dependent pore block by calcium for the NR1Q mutant mimicked the effects of the positively charged Arg at this site in NR1R on slowing desensitization and deactivation. A kinetic model of the NMDA receptor-channel suggests that these results can be explained by altered gating and not ligand binding. Our data increase understanding of the role that amino acids within the NMDAR pore play in channel gating

    Women and non-cardiac chest pain: gender differences in symptom presentation.

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    A substantial number of individuals evaluated for complaints of chest pain do not suffer from coronary heart disease (CHD). Studies show that many patients who complain of symptoms that might be caused by CHD, such as shortness of breath or chest pain, may actually have an anxiety disorder. Gender differences in how patients present with these symptoms have not been adequately explored. The purpose of this study was to explore possible gender differences in the presentation of patients with CHD-like symptoms. Two groups were examined, one comprising 6,381 individuals self-referred for electron beam tomography (EBT) studies and a subset of these individuals who defined a low-risk group based on the absence of risk factors for CHD and low coronary artery calcium (CAC) scores. We explored gender differences in symptom presentation in each group after controlling for relevant variables by using logistic regression models. These analyses showed that women were significantly more likely than men to endorse CHD symptoms that might also be caused by an anxiety disorder. Women in the low risk group reported CHD symptoms also referable to anxiety more often than men, but unlike men did not complain primarily of chest pain. Women were also more likely to have been prescribed antianxiety or antidepressant medication. In previous studies, non-cardiac chest pain has been considered a hallmark of anxiety in individuals seen in medical settings. This study suggests that in individuals with low risk for CHD chest pain was not related to gender, but other anxiety-related symptoms including heart flutter, lightheadedness, nausea, and shortness of breath were more likely to be reported in women than in men

    High Spatial Resolution Observations of Two Young Protostars in the R Corona Australis Region

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    We present multi-wavelength, high spatial resolution imaging of the IRS 7 region in the R Corona Australis molecular cloud. Our observations include 1.1 mm continuum and HCO^+ J = 3→23 \to 2 images from the SMA, ^{12}CO J = 3→23 \to 2 outflow maps from the DesertStar heterodyne array receiver on the HHT, 450 μ\mum and 850 μ\mum continuum images from SCUBA, and archival Spitzer IRAC and MIPS 24 \micron images. The accurate astrometry of the IRAC images allow us to identify IRS 7 with the cm source VLA 10W (IRS 7A) and the X-ray source X_W. The SMA 1.1 mm image reveals two compact continuum sources which are also distinguishable at 450 μ\mum. SMA 1 coincides with X-ray source CXOU J190156.4-365728 and VLA cm source 10E (IRS 7B) and is seen in the IRAC and MIPS images. SMA 2 has no infrared counterpart but coincides with cm source VLA 9. Spectral energy distributions constructed from SMA, SCUBA and Spitzer data yield bolometric temperatures of 83 K for SMA 1 and ≤\leq70 K for SMA 2. These temperatures along with the submillimeter to total luminosity ratios indicate that SMA 2 is a Class 0 protostar, while SMA 1 is a Class 0/Class I transitional object (L=17±617\pm6 \Lsun). The ^{12}CO J = 3→23 \to 2 outflow map shows one major and possibly several smaller outflows centered on the IRS 7 region, with masses and energetics consistent with previous work. We identify the Class 0 source SMA 2/VLA 9 as the main driver of this outflow. The complex and clumpy spatial and velocity distribution of the HCO^+ J = 3→23 \to 2 emission is not consistent with either bulk rotation, or any known molecular outflow activity.Comment: 31 pages, 8 figures, Accepted to Ap

    The farmer as a landscape steward: Comparing local understandings of landscape stewardship, landscape values, and land management actions

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    We develop a landscape stewardship classification which distinguishes between farmers’ understanding of landscape stewardship, their landscape values, and land management actions. Forty semi-structured interviews were conducted with smallholder (5 acres), medium-holders (5-100 acres), and large- holders (100 acres) in South-West Devon, UK. Thematic analysis revealed four types of stewardship understandings: (1) an environmental frame which emphasized the farmers’ role in conserving or restoring wildlife; (2) a primary production frame which emphasized the farmers’ role in taking care of primary production assets; (3) a holistic frame focusing on farmers’ role as a conservationist, primary producer, and manager of a range of landscape values, and; (4) an instrumental frame focusing on the financial benefits associated with compliance with agri-environmental schemes. We compare the landscape values and land management actions that emerged across stewardship types, and discuss the global implications of the landscape stewardship classification for the engagement of farmers in landscape management

    Magnetic structure of CeRhIn5_{5} under magnetic field

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    The magnetically ordered ground state of CeRhIn5_{5} at ambient pressure and zero magnetic field is an incomensurate helicoidal phase with the propagation vector k\bf{k}=(1/2, 1/2, 0.298) and the magnetic moment in the basal plane of the tetragonal structure. We determined by neutron diffraction the two different magnetically ordered phases of CeRhIn5_{5} evidenced by bulk measurements under applied magnetic field in its basal plane. The low temperature high magnetic phase corresponds to a sine-wave structure of the magnetization being commensurate with k\bf{k}=(1/2, 1/2, 1/4). At high temperature, the phase is incommensurate with k\bf{k}=(1/2, 1/2, 0.298) and a possible small ellipticity. The propagation vector of this phase is the same as the one of the zero-field structure.Comment: 4 Figure

    Detection of an X-Ray Hot Region in the Virgo Cluster of Galaxies with ASCA

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    Based on mapping observations with ASCA, an unusual hot region with a spatial extent of 1 square degree was discovered between M87 and M49 at a center coordinate of R. A. = 12h 27m 36s and Dec. = 9∘18′9^\circ18' (J2000). The X-ray emission from the region has a 2-10 keV flux of 1×10−111 \times 10^{-11} ergs s−1^{-1} cm−2^{-2} and a temperature of kT≳4kT \gtrsim 4 keV, which is significantly higher than that in the surrounding medium of ∼2\sim 2 keV. The internal thermal energy in the hot region is estimated to be VnkT∼1060V n k T \sim 10^{60} ergs with a gas density of ∼10−4\sim 10^{-4} cm−3^{-3}. A power-law spectrum with a photon index 1.7−2.31.7-2.3 is also allowed by the data. The hot region suggests there is an energy input due to a shock which is probably caused by the motion of the gas associated with M49, infalling toward the M87 cluster with a velocity ≳1000\gtrsim 1000 km s−1^{-1}.Comment: 12 pages, 3 figures, accepted to ApJ

    Habitable Planet Formation in Binary-Planetary Systems

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    Recent radial velocity observations have indicated that Jovian-type planets can exist in moderately close binary star systems. Numerical simulations of the dynamical stability of terrestrial-class planets in such environments have shown that, in addition to their giant planets, these systems can also harbor Earth-like objects. In this paper, we study the late stage of terrestrial planet formation in such binary-planetary systems, and present the results of the simulations of the formation of Earth-like bodies in their habitable zones. We consider a circumprimary disk of Moon- to Mars-sized objects and numerically integrate the orbits of these bodies at the presence of the Jovian-type planet of the system and for different values of the mass, semimajor axis, and orbital eccentricity of the secondary star. Results indicate that, Earth-like objects, with substantial amounts of water, can form in the habitable zone of the primary star. Simulations also indicate that, by transferring angular momentum from the secondary star to protoplanetary objects, the giant planet of the system plays a key role in the radial mixing of these bodies and the water contents of the final terrestrial planets. We will discuss the results of our simulation and show that the formation of habitable planets in binary-planetary systems is more probable in binaries with moderate to large perihelia.Comment: 27 pages, 11 figures, submitted for publicatio
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