1,098 research outputs found
Simulating geometric uncertainties of impervious areas based on image segmentation accuracy metrics
International audienceUrban sprawl monitoring is important for developing land management policies at various spatial scales. Segmentation and classification of satellite images allows obtaining polygons of impervious areas regularly over large areas, e.g. as has been implemented for the region Languedoc‐Roussillon in the south of France using 5 m RapidEye images. Starting from the results of this previous study, we aim to: i) evaluate the geometric and thematic accuracy of the impervious polygons (S) using segmentation accuracy metrics, and ii) use these metrics to simulate polygons having the same level of uncertainty. A manual segmentation (M) was used to evaluate the accuracy. After matching the polygons, the distance (d) and azimuth (a) of each vertex of M to the closest segment of the boundary of S was calculated. Spherically correlated random fields of d and a were used to randomly move the vertices of S. Realistic simulations of impervious polygons were obtained
Energy and angular momentum sharing in dissipative collisions
Primary and secondary masses of heavy reaction products have been deduced
from kinematics and E-ToF measurements, respectively, for the direct and
reverse collisions of 93Nb and 116Sn at 25 AMeV. Light charged particles have
also been measured in coincidence with the heavy fragments.
Direct experimental evidence of the correlation of energy-sharing with net
mass transfer has been found using the information from both the heavy
fragments and the light charged particles.
The ratio of Hydrogen and Helium multiplicities points to a further
correlation of angular momentum sharing with net mass transfer.Comment: 21 pages, 20 figures. Submitted to European Physics Journal
Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2α overexpression
International audienceBACKGROUND: Activator protein-2alpha (AP-2alpha) is a transcription factor that belongs to the family of AP-2 proteins that have essential roles in tumorigenesis. Indeed, AP-2alpha is considered as a tumour-suppressor gene in different tissues such as colonic, prostatic or breast epithelial cells. Moreover, AP-2alpha also participates in the control of colon and breast cancer cells sensitivity towards chemotherapeutic drugs. Despite its potential interest, very few data are available regarding the roles of AP-2alpha in pancreatic cancer. METHODS: We have developed a stable pancreatic CAPAN-1 cell line overexpressing AP-2alpha. Consequences of overexpression were studied in terms of in vivo cell growth, gene expression, migration capacity and chemosensitivity. RESULTS: In vivo tumour growth of CAPAN-1 cells overexpressing AP-2alpha was significantly decreased by comparison to control cells. An altered expression pattern of cell cycle-controlling factors (CDK-4, CDK-6, cyclin-G1, p27(kip1) and p57(kip2)) was observed in AP-2alpha-overexpressing clones by microarrays and western blot analysis. Promoter activity and ChIP analysis indicated that AP-2alpha induces p27(kip1) protein levels by direct binding to and transactivation of its promoter. Moreover, AP-2alpha overexpression increased the chemosensitivity of CAPAN-1 cells to low doses of gemcitabine and reduced their in vitro migration capacity. CONCLUSION: Our data suggested that AP-2alpha overexpression could be exploited to decrease in vivo tumour growth of pancreatic cancer cells and to increase their sensitivity to gemcitabine
One-neutron removal reactions on neutron-rich psd-shell nuclei
A systematic study of high energy, one-neutron removal reactions on 23
neutron-rich, psd--shell nuclei (Z=5-9, A=12-25) has been carried out. The
longitudinal momentum distributions of the core fragments and corresponding
single-neutron removal cross sections are reported for reactions on a carbon
target. Extended Glauber model calculations, weighted by the spectroscopic
factors obtained from shell model calculations, are compared to the
experimental results. Conclusions are drawn regarding the use of such reactions
as a spectroscopic tool and spin-parity assignments are proposed for 15B, 17C,
19-21N, 21,23O, 23-25F. The nature of the weakly bound systems 14B and 15,17C
is discussed.Comment: 11 pages + 2 figure
One-neutron removal reactions on light neutron-rich nuclei
A study of high energy (43--68 MeV/nucleon) one-neutron removal reactions on
a range of neutron-rich psd-shell nuclei (Z = 5--9, A = 12--25) has been
undertaken. The inclusive longitudinal and transverse momentum distributions
for the core fragments, together with the cross sections have been measured for
breakup on a carbon target. Momentum distributions for reactions on tantalum
were also measured for a subset of nuclei. An extended version of the Glauber
model incorporating second order noneikonal corrections to the JLM
parametrisation of the optical potential has been used to describe the nuclear
breakup, whilst the Coulomb dissociation is treated within first order
perturbation theory. The projectile structure has been taken into account via
shell model calculations employing the psd-interaction of Warburton and Brown.
Both the longitudinal and transverse momentum distributions, together with the
integrated cross sections were well reproduced by these calculations and
spin-parity assignments are thus proposed for B, C, N,
O, F. In addition to the large spectroscopic amplitudes for
the s intruder configuration in the N=9 isotones,B and
C, significant s admixtures appear to occur in the
ground state of the neighbouring N=10 nuclei B and C. Similarly,
crossing the N=14 subshell, the occupation of the s orbital is
observed for O, F. Analysis of the longitudinal and transverse
momentum distributions reveals that both carry spectroscopic information, often
of a complementary nature. The general utility of high energy nucleon removal
reactions as a spectroscopic tool is also examined.Comment: 50 pages, 19 figures, submitted to Phys. Rev.
Collapse of the N=28 shell closure in Si
The energies of the excited states in very neutron-rich Si and
P have been measured using in-beam -ray spectroscopy from the
fragmentation of secondary beams of S at 39 A.MeV. The low 2
energy of Si, 770(19) keV, together with the level schemes of
P provide evidence for the disappearance of the Z=14 and N=28
spherical shell closures, which is ascribed mainly to the action of
proton-neutron tensor forces. New shell model calculations indicate that
Si is best described as a well deformed oblate rotor.Comment: 4 pages, 3 figures, accepted for publication in Phys. Rev. let
Prolate-Spherical Shape Coexistence at N=28 in S
The structure of S has been studied using delayed and
electron spectroscopy at \textsc{ganil}. The decay rates of the 0
isomeric state to the 2 and 0 states have been measured for the
first time, leading to a reduced transition probability
B(E2~:~20= 8.4(26)~efm and a monopole
strength (E0~:~00
=~8.7(7)10. Comparisons to shell model calculations point
towards prolate-spherical shape coexistence and a phenomenological two level
mixing model is used to extract a weak mixing between the two configurations.Comment: 5 pages, 3 figures, accepted for publication in Physical Review
Letter
ECR Ion sources for radioactive ion beam production
17th workshop on ECR Ion Sources and their Applications, Lanzhou, Chine (2006)International audienceECRIS's dedicated to radioactive ion producton must be as efficient as those used for production of stable elements, but in addition they are subject to more specific constraints such as radiation hardness, short atom-to-ion transformation time, beam purity and low cost. Up to now, different target/ion-source system (TISSs) have been designed, using singly-charged ECRISs, multi-charged ion sources or an association of singly-to-multi-charged ECRISs. The main goal, constraints and advantages of different existing ECR setups wil be compared before a more detailed description is given of the one designed for the SPIRAL II project and ist future improvements
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