106 research outputs found

    Using the electronic information and educational environment of the university in the training of tourism industry workers

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    The availability of electronic information and educational environment of an educational institution today is the most important requirement of the Federal state educational standards of higher education in all areas of preparation for the conditions of implementation of educational programs by universities. The purpose of the study is to rationale for use in modern educational process of the University electronic information-educational environment and study of its use in training future employees of the tourism industry. Research methodology: system-structural, competence-based, informational approaches; research methods: theoretical (analysis of normative documents, local acts of the University, experience in implementing the electronic information and educational environment at the University, comparison, synthesis of educational and methodological knowledge on the research problem, the method of analogy, forecasting; empirical (observation, study of educational products, description). The research was carried out on the basis of the faculty of service and tourism of the Kuban state University of physical culture, sport and tourism. Results: the necessity of using the modern educational process of higher school of electronic information and educational environment, discloses the functionality and experience of using electronic information-educational environment in the professional training of tourism industry personnel; the structural-functional components and design principles of the electronic information-educational environment of the University; the ways of implementing forms of educational activities with the use of e-learning technologies in the process of training future employees of the tourism industry and their advantages are revealed. Conclusions: the electronic information and educational environment of a University is a set of tools and resources based on information and communication technologies aimed at ensuring the requirements for the implementation of educational activities; in the training of future employees of the tourist industry used the following electronic information-educational environment: electronic library system; e-library of the University; module "qualifying work" on the platform MEGAPRO, Date Express LLC, management system training courses (virtual learning environments); information system "Document of the University"; the software package "Plans"; system "Antiplagiat.VUZ " electronic portfolio and other components; the advantages of using electronic information and educational environment are: the ability to build the educational process with active interaction of all subjects of the educational system; prompt informing of participants of educational activities about changes in the educational process; the ability to form various virtual communities, etc

    Motor activity of Daphnia magna (Crustacea, Cladocera) during thermal selection: Peculiarities of search reactions in the non-uniform environment

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    We conducted a study of the peculiarities of the motor activity of juvenile and adult individuals of Daphnia magna in the process of thermal selection. On the example of Daphnia, we experimentally proved the assumption that the decrease in the motor activity of the ectotherms in the selected temperature range is a behaviour mechanism typical for thermal selection. The experiment was conducted on the offspring of one parthenogenetic female (pure line) of a laboratory culture maintained over several years at room temperature. The Daphnia individuals had been beforehand acclimated over several generations to 23.4 ΒΊΠ‘, and then were placed in a thermogradient apparatus. The control individuals were maintained at room temperature. The final temperature preference was determined using the so-called "chronic" method, when the tested organisms are maintained in a thermogradient apparatus over several days. TheΒ positions of the Daphnia individuals were recorded daily during 24 days. As a parameter which would characterize the motor activity of Daphnia, we used the parameter of average relative shifting, which was calculated as a difference (in cm) between the position they were found in two sequential records, divided by time (in min) between these records. Over the first 3 days, in the conditions of the temperature gradient, the Daphnia mostly selected heightened temperatures (24–28 ΒΊΠ‘). During the period from the 4th to 24th day, 74% of the Daphnia selected the range of 18–23Β ΒΊΠ‘ and 85% – 17–24 ΒΊΠ‘. Thus, the range of the ultimate selected temperatures decreased by 4 ΒΊΠ‘ compared to the initially selected temperatures and enlarged by 3 ΒΊΠ‘ towards the lower temperatures. In the thermogradient apparatus, the parthenogenetic females had the lowest value of the mean relative movement. In the control, at room temperature, this parameter of the adults was by 43% higher compared to the gradient. The pattern of the dynamic of the indicator in both variants of the experiment was similar for the periods and phases of fluctuations. With the juveniles the value of the parameter of mean relative shifting in the gradient was higher by 40% compared to the adult Daphnia, but close to the parameter of the adults in the control. We determined a relationship between the juveniles selecting the higher temperatures and higher mean relative shifting, which indicates a relationship between the behavioural selective reaction of juvenile Daphnia and general physiological condition of their organism. During the absence of the temperature gradient, the Daphnia were observed to show symmetry in their motor reaction. Occurrence of the asymmetry of the motor reaction of the Daphnia in the condition of the thermogradient, manifesting in the prevalence of shifting to lower or higher temperatures, can indicate more clearly manifested search reaction in the condition of a non-uniform environment

    Life safety culture as a pedagogical problem

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    It is well known that security is a necessary condition for the long-term development of humanity, society, the state and civilization as a whole, ensuring their stability and success. Currently, the Russian Federation pays close attention to the issues of educating the younger generation about a culture of life safety, which is supported by government initiatives, because ensuring the safety of the state citizens is among the priority components of a high standard of living. It is the culture of life safety that is defined as a component of the general culture of an individual and the main target for the activities of educational organizations. In this regard, the problem of the research is to substantiate the culture of life safety as a pedagogical category. The purpose of the research is to substantiate the content of the concept of β€œlife safety culture” as a subject of pedagogical discourse and the basic target of the state educational policy. The methodological basis of the research is represented by the use of methods of analysis, theoretical generalization, and description.The results of the research are as follows: various approaches to the content of the concept of β€œlife safety culture” as a pedagogical category have been analyzed; the structural components of safety culture have been identified; the target guidelines for instilling a life safety culture in educational institutions have been substantiated.Key conclusions: the issues of developing a culture of life safety among students have been considered in two contexts, as a necessary condition for the activities of teachers in developing the experience of safe behavior of students and as the creation of pedagogical conditions for a safe educational environment by all participants in educational activities. The target guidelines for instilling a culture of life safety among students are an integrated set of the following components: psychological, political, economic, environmental and information security of an individual

    Trophic diversification and parasitic invasion as ecological niche modulators for gut microbiota of whitefish

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    Introduction: The impact of parasites on gut microbiota of the host is well documented, but the role of the relationship between the parasite and the host in the formation of the microbiota is poorly understood. This study has focused on the influence that trophic behavior and resulting parasitism has on the structure of the microbiome. Methods: Using 16S amplicon sequencing and newly developed methodological approaches, we characterize the gut microbiota of the sympatric pair of whitefish Coregonus lavaretus complex and the associated microbiota of cestodes parasitizing their intestine. The essence of the proposed approaches is, firstly, to use the method of successive washes of the microbiota from the cestode’s surfaces to analyze the degree of bacterial association to the tegument of the parasite. Secondly, to use a method combining the sampling of intestinal content and mucosa with the washout procedure from the mucosa to understand the real structure of the fish gut microbiota. Results and discussion: Our results demonstrate that additional microbial community in the intestine are formed by the parasitic helminths that caused the restructuring of the microbiota in infected fish compared to those uninfected. Using the desorption method in Ringer’s solution, we have demonstrated that Proteocephalus sp. cestodes possess their own microbial community which is put together from β€œsurface” bacteria, and bacteria which are weakly and strongly associated with the tegument, bacteria obtained after treatment of the tegument with detergent, and bacteria obtained after removal of the tegument from the cestodes.info:eu-repo/semantics/publishedVersio

    Modern features of innovative strategies for the development of hotel business enterprises

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    The hotel business is the basic sector of the tourism industry, contributes to the increase in tourist flows, the internationalization of financial capital, and the growth of employment. The hotel sector is developing rapidly (with the exception of 2020, which is explained by anti-Covid measures), largely due to the introduction of innovative development strategies. The investment prospects of the hotel sector should be built on the basis of such a systematization of modern innovative trends, and business planning of the activities of hotel enterprises should ensure the best implementation of innovative approaches when developing a strategy in a specific business environment. The purpose of the study is to study the modern features of innovative strategies for the development of hotel business enterprises, their impact on the dynamics of sales of paid services to the population, including the example of the Krasnodar Territory. The research methods are the following: statistical method, competitive analysis method, generalization method, forecasting. The results and conclusions: an analysis of the applied innovative strategies by hospitality enterprises indicates that such strategies are effective tools for effectively solving the problem of survival and ensuring the business security of hotels. Conclusions: innovative strategies are the most important part of the strategic management of a hotel enterprise, they make it possible to strengthen its competitiveness, meet the constantly changing preferences of guests, follow industry trends or even outstrip them

    Modern features of benchmarking in the hotel business

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    The market of hotel services is an actively developing market in which innovative technologies of service of guests are widely used; various loyalty and reservation programs are being developed and improved; new approaches to business process management are applied. Benchmarking is a very relevant area designed to assess and select alternative options for the development of the hotel business, defining tasks and improving management efficiency through a deeper study and borrowing approaches successfully implemented by competitors. The aim of the research is to study the current features of benchmarking in the hospitality industry and its impact on the dynamics of enterprise performance. The research methods used are method of competitive analysis, statistical method, generalization method, forecasting. The results and conclusions: the analysis of the state of the hotel services market has shown a steady growth in the number of facilities and consumers of hotel services, which leads to increased intra-industry competition. Benchmarking helps to correlate the operating performance of the hotel business with the performance of the competitive environment, to move away from the subjective assessments of hoteliers and to identify errors in sales policy. In addition, the use of benchmarking allows you to predict the dynamics of demand in order to minimize managerial errors. The conclusions: benchmarking is part of marketing research and the basis for business process planning in the context of choosing strategic activities of the hotel service company. Conducting such a study is focused on providing the hotel with significant competitive advantages, the quintessence of which is the procedure of studying the experience of operating in the market of business leaders

    ΠŸΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π±Π°Ρ€ΡŒΠ΅Ρ€Π½Ρ‹Ρ… слоСв диоксида Ρ‚ΠΈΡ‚Π°Π½Π° для формирования ΠΌΡƒΠ»ΡŒΡ‚ΠΈΡ„Π΅Ρ€Ρ€ΠΎΠΈΠΊΠΎΠ² Ρ„Π΅Ρ€Ρ€ΠΎΠΌΠ°Π³Π½Π΅Ρ‚ΠΈΠΊ/сСгнСтоэлСктрик

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    The layered multiferroics Co/PZT were obtained by ion-beam sputtering-deposition method, where PZT is a ferroelectric ceramic based on lead titanate zirconate of the composition PbZr0.45Ti0.55O3 with a thermostable plane-parallel ferroelectric/ferromagnet interface. Using cross-sectional scanning electron microscopy (SEM), we studied the interface of a cobalt layer up to several micrometers thick with a thick ceramic substrate of lead zirconate titanate. It has been shown that the use of a titanium dioxide barrier layer of TiO2 instead of PZT allows quality improvement of the interface by reducing the duration of ion-beam planarization of the ferroelectric substrate, and also to eliminate the formation of intermediate chemical compounds. Based on the data of X-ray phase analysis (XRD), it was concluded that the TiO2 layer is amorphous. Magnetoelectric measurements have shown that the use of titanium dioxide instead of PZT under appropriate planarization modes can increase the low-frequency magnetoelectric effect to 5 mV/(cmβˆ™ΠžΠ΅), compared with structures with a sputtering planarizing layer of PZT, where the magnitude of the low-frequency magnetoelectric effect is 2 mV/(cmβˆ™Πže). These results allow us to improve the characteristics of these structures when used as sensitive elements in devices for formation – processing of information and magnetic field sensors based on the magnetoelectric effect.Π‘ ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ ΠΌΠ΅Ρ‚ΠΎΠ΄Π° ΠΈΠΎΠ½Π½ΠΎ-Π»ΡƒΡ‡Π΅Π²ΠΎΠ³ΠΎ распылСния – осаТдСния ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Ρ‹ слоистыС ΠΌΡƒΠ»ΡŒΡ‚ΠΈΡ„Π΅Ρ€Ρ€ΠΎΠΈΠΊΠΈ Co/Π¦Π’Π‘ (Π¦Π’Π‘ – сСгнСтоэлСктричСская ΠΊΠ΅Ρ€Π°ΠΌΠΈΠΊΠ° Π½Π° основС Ρ†ΠΈΡ€ΠΊΠΎΠ½Π°Ρ‚Π° Ρ‚ΠΈΡ‚Π°Π½Π°Ρ‚Π° свинца состава PbZr0,45Ti0,55O3 с Ρ‚Π΅Ρ€ΠΌΠΎΡΡ‚Π°Π±ΠΈΠ»ΡŒΠ½Ρ‹ΠΌ ΠΏΠ»ΠΎΡΠΊΠΎΠΏΠ°Ρ€Π°Π»Π»Π΅Π»ΡŒΠ½Ρ‹ΠΌ интСрфСйсом сСгнСтоэлСктрик/Ρ„Π΅Ρ€Ρ€ΠΎΠΌΠ°Π³Π½Π΅Ρ‚ΠΈΠΊ), ΠΎΠ±Π»Π°Π΄Π°ΡŽΡ‰ΠΈΠ΅ воспроизводимыми низкочастотными магнитоэлСктричСскими характСристиками ΠΏΡ€ΠΈ ΠΊΠΎΠΌΠ½Π°Ρ‚Π½ΠΎΠΉ Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Π΅. ΠœΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ растровой элСктронной микроскопии (РЭМ) ΠΏΠΎΠΏΠ΅Ρ€Π΅Ρ‡Π½ΠΎΠ³ΠΎ сСчСния исслСдована Π³Ρ€Π°Π½ΠΈΡ†Π° Ρ€Π°Π·Π΄Π΅Π»Π° слоя ΠΊΠΎΠ±Π°Π»ΡŒΡ‚Π° Ρ‚ΠΎΠ»Ρ‰ΠΈΠ½ΠΎΠΉ Π΄ΠΎ Π½Π΅ΡΠΊΠΎΠ»ΡŒΠΊΠΈΡ… ΠΌΠΈΠΊΡ€ΠΎΠΌΠ΅Ρ‚Ρ€ΠΎΠ² с толстой кСрамичСской ΠΏΠΎΠ΄Π»ΠΎΠΆΠΊΠΎΠΉ Ρ†ΠΈΡ€ΠΊΠΎΠ½Π°Ρ‚Π° – Ρ‚ΠΈΡ‚Π°Π½Π°Ρ‚Π° свинца. Показано, Ρ‡Ρ‚ΠΎ использованиС Π±Π°Ρ€ΡŒΠ΅Ρ€Π½ΠΎΠ³ΠΎ слоя диоксида Ρ‚ΠΈΡ‚Π°Π½Π° TiO2 вмСсто Π¦Π’Π‘ позволяСт Π΄ΠΎΠ±ΠΈΡ‚ΡŒΡΡ ΡƒΠ»ΡƒΡ‡ΡˆΠ΅Π½ΠΈΡ качСства интСрфСйса Π·Π° счСт ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΡ Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ ΠΈΠΎΠ½Π½ΠΎ-Π»ΡƒΡ‡Π΅Π²ΠΎΠΉ ΠΏΠ»Π°Π½Π°Ρ€ΠΈΠ·Π°Ρ†ΠΈΠΈ сСгнСтоэлСктричСской ΠΏΠΎΠ΄Π»ΠΎΠΆΠΊΠΈ, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΈΡΠΊΠ»ΡŽΡ‡ΠΈΡ‚ΡŒ ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΡ€ΠΎΠΌΠ΅ΠΆΡƒΡ‚ΠΎΡ‡Π½Ρ‹Ρ… химичСских соСдинСний. На основС Π΄Π°Π½Π½Ρ‹Ρ… Ρ€Π΅Π½Ρ‚Π³Π΅Π½ΠΎΡ„Π°Π·ΠΎΠ²ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π° (РЀА) сдСлан Π²Ρ‹Π²ΠΎΠ΄ ΠΎΠ± аморфности слоя TiO2, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΉ ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с кристалличСским позволяСт Π±ΠΎΠ»Π΅Π΅ Ρ€Π°Π²Π½ΠΎΠΌΠ΅Ρ€Π½ΠΎ, Π±Π΅Π· искаТСний, ΠΏΠ΅Ρ€Π΅Π΄Π°Π²Π°Ρ‚ΡŒ Π²Π½ΡƒΡ‚Ρ€Π΅Π½Π½ΠΈΠ΅ напряТСния, Π²ΠΎΠ·Π½ΠΈΠΊΠ°ΡŽΡ‰ΠΈΠ΅ ΠΌΠ΅ΠΆΠ΄Ρƒ сСгнСтоэлСктричСской ΠΏΠΎΠ΄Π»ΠΎΠΆΠΊΠΎΠΉ ΠΈ Ρ„Π΅Ρ€Ρ€ΠΎΠΌΠ°Π³Π½ΠΈΡ‚Π½Ρ‹ΠΌ слоСм. Π­Ρ‚ΠΎ ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ Π±ΠΎΠ»Π΅Π΅ эффСктивному магнитоэлСктричСскому Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡ‚Π²ΠΈΡŽ ΠΈ Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΌΡƒ ΠΏΠΎ Π²Π΅Π»ΠΈΡ‡ΠΈΠ½Π΅ (Π² Π΅Π΄ΠΈΠ½ΠΈΡ†Ρ‹ – дСсятки ΠΌΠ’/А) низкочастотному магнитоэлСктричСскому эффСкту ΠΏΡ€ΠΈ ΠΊΠΎΠΌΠ½Π°Ρ‚Π½ΠΎΠΉ Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Π΅. ΠœΠ°Π³Π½ΠΈΡ‚ΠΎΡΠ»Π΅ΠΊΡ‚Ρ€ΠΈΡ‡Π΅ΡΠΊΠΈΠ΅ измСрСния ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΈ, Ρ‡Ρ‚ΠΎ использованиС диоксида Ρ‚ΠΈΡ‚Π°Π½Π° вмСсто Π¦Π’Π‘ ΠΏΡ€ΠΈ ΡΠΎΠΎΡ‚Π²Π΅Ρ‚ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΡ… Ρ€Π΅ΠΆΠΈΠΌΠ°Ρ… ΠΏΠ»Π°Π½Π°Ρ€ΠΈΠ·Π°Ρ†ΠΈΠΈ ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΡŽ низкочастотного магнитоэлСктричСского эффСкта Π΄ΠΎ 5 ΠΌΠ’/(см βˆ™Π­) ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ со структурами с Π½Π°ΠΏΡ‹Π»Π΅Π½ΠΈΠ΅ΠΌ ΠΏΠ»Π°Π½Π°Ρ€ΠΈΠ·ΡƒΡŽΡ‰Π΅Π³ΠΎ слоя Π¦Π’Π‘, Π³Π΄Π΅ Π²Π΅Π»ΠΈΡ‡ΠΈΠ½Π° Π΄Π°Π½Π½ΠΎΠ³ΠΎ эффСкта составляСт 2 ΠΌΠ’/(см βˆ™Π­). Π­Ρ‚ΠΈ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‚ ΡƒΠ»ΡƒΡ‡ΡˆΠΈΡ‚ΡŒ характСристики ΡƒΠΊΠ°Π·Π°Π½Π½Ρ‹Ρ… структур ΠΏΡ€ΠΈ использовании Π² качСствС Ρ‡ΡƒΠ²ΡΡ‚Π²ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… элСмСнтов Π² устройствах формирования – ΠΎΠ±Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΈ ΠΈ Π΄Π°Ρ‚Ρ‡ΠΈΠΊΠΎΠ² ΠΌΠ°Π³Π½ΠΈΡ‚Π½ΠΎΠ³ΠΎ поля Π½Π° основС магнитоэлСктричСского эффСкта

    Π›ΠΎΠΊΠ°Π»ΡŒΠ½Ρ‹ΠΉ Ρ‚ΡƒΠ±Π΅Ρ€ΠΊΡƒΠ»Π΅Π· Ρƒ Π΄Π΅Ρ‚Π΅ΠΉ Ρ€Π°Π½Π½Π΅Π³ΠΎ возраста

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    TheΒ purpose isΒ toΒ study clinical andΒ X-ray manifestations ofΒ local tuberculosis inΒ children ofΒ theΒ tender age andΒ toΒ detect risk factors promoting theΒ development ofΒ theΒ disease andΒ complicating it, thus theΒ analysis included 82 cases ofΒ children cases underΒ 3 years old who had been treated inΒ Children TB Hospital inΒ 2013-2015. Tuberculosis ofΒ chest lymph nodes was diagnosed inΒ 68.3%ofΒ them, andΒ every fifth child had primary tuberculosis complex. Every other child was suffering fromΒ theΒ complicated course ofΒ local tuberculosis (n =Β 42). TheΒ following forms were registered: bronchial pulmonary lesions (n =Β 27), lymphogenic progression (n =Β 13), including development ofΒ disseminated tuberculosis andΒ meningitis. Positive results ofΒ sputum tests were observed inΒ 14 (17.1%) children, ofΒ them 50% had multiple drug resistance. 10% ofΒ children suffering fromΒ tuberculosis manifested anergy. TheΒ predictors ofΒ such course ofΒ theΒ disease included theΒ absence ofΒ BCG vaccination andΒ super infection with MycobacteriumΒ tuberculosis.Π‘ Ρ†Π΅Π»ΡŒΡŽ изучСния ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΎ-рСнтгСнологичСских проявлСний локального Ρ‚ΡƒΠ±Π΅Ρ€ΠΊΡƒΠ»Π΅Π·Π° Ρƒ Π΄Π΅Ρ‚Π΅ΠΉ Ρ€Π°Π½Π½Π΅Π³ΠΎ возраста ΠΈ выявлСния Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² риска, ΡΠΏΠΎΡΠΎΠ±ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΡ… Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΡŽ заболСвания ΠΈ ΠΎΡ‚ΡΠ³ΠΎΡ‰Π°ΡŽΡ‰ΠΈΡ… Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Ρ‚ΡƒΠ±Π΅Ρ€ΠΊΡƒΠ»Π΅Π·Π½ΠΎΠ³ΠΎ процСсса, ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· 82 историй Π±ΠΎΠ»Π΅Π·Π½ΠΈ Π΄Π΅Ρ‚Π΅ΠΉ Π² возрастС Π΄ΠΎ 3 Π»Π΅Ρ‚, Π»Π΅Ρ‡ΠΈΠ²ΡˆΠΈΡ…ΡΡ Π² ДСтской Ρ‚ΡƒΠ±Π΅Ρ€ΠΊΡƒΠ»Π΅Π·Π½ΠΎΠΉ Π±ΠΎΠ»ΡŒΠ½ΠΈΡ†Π΅ Π² 2013-2015 Π³Π³. Π’ΡƒΠ±Π΅Ρ€ΠΊΡƒΠ»Π΅Π· Π²Π½ΡƒΡ‚Ρ€ΠΈΠ³Ρ€ΡƒΠ΄Π½Ρ‹Ρ… лимфатичСских ΡƒΠ·Π»ΠΎΠ² диагностировали Ρƒ 68,3%, ΠΏΠ΅Ρ€Π²ΠΈΡ‡Π½Ρ‹ΠΉ Ρ‚ΡƒΠ±Π΅Ρ€ΠΊΡƒΠ»Π΅Π·Π½Ρ‹ΠΉ комплСкс - Ρƒ ΠΊΠ°ΠΆΠ΄ΠΎΠ³ΠΎ пятого. ОслоТнСнноС Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π»ΠΎΠΊΠ°Π»ΡŒΠ½Ρ‹Ρ… Ρ„ΠΎΡ€ΠΌ - Ρƒ ΠΊΠ°ΠΆΠ΄ΠΎΠ³ΠΎ Π²Ρ‚ΠΎΡ€ΠΎΠ³ΠΎ (n = 42). Π Π΅Π³ΠΈΡΡ‚Ρ€ΠΈΡ€ΠΎΠ²Π°Π»ΠΈΡΡŒ: Π±Ρ€ΠΎΠ½Ρ…ΠΎΠ»Π΅Π³ΠΎΡ‡Π½Ρ‹Π΅ пораТСния (n = 27), Π»ΠΈΠΌΡ„ΠΎΠ³Π΅ΠΌΠ°Ρ‚ΠΎΠ³Π΅Π½Π½ΠΎΠ΅ прогрСссированиС (n = 13), Π² Ρ‚ΠΎΠΌ числС с Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ΠΌ диссСминированного Ρ‚ΡƒΠ±Π΅Ρ€ΠΊΡƒΠ»Π΅Π·Π°, ΠΌΠ΅Π½ΠΈΠ½Π³ΠΈΡ‚Π°. Π‘Π°ΠΊΡ‚Π΅Ρ€ΠΈΠΎΠ²Ρ‹Π΄Π΅Π»Π΅Π½ΠΈΠ΅ - Ρƒ 14 (17,1%) Π΄Π΅Ρ‚Π΅ΠΉ, ΠΈΠ· Π½ΠΈΡ… с мноТСствСнной лСкарствСнной ΡƒΡΡ‚ΠΎΠΉΡ‡ΠΈΠ²ΠΎΡΡ‚ΡŒΡŽ возбудитСля - Ρƒ 50,0%. Π’ΡƒΠ±Π΅Ρ€ΠΊΡƒΠ»Π΅Π· Ρƒ 10% Π΄Π΅Ρ‚Π΅ΠΉ ΠΏΡ€ΠΎΡ‚Π΅ΠΊΠ°Π» Π½Π° Ρ„ΠΎΠ½Π΅ Π°Π½Π΅Ρ€Π³ΠΈΠΈ. К ΠΏΡ€Π΅Π΄ΠΈΠΊΡ‚ΠΎΡ€Π°ΠΌ Ρ‚Π°ΠΊΠΎΠ³ΠΎ тСчСния отнСсСны отсутствиС ΠΏΡ€ΠΈΠ²ΠΈΠ²ΠΊΠΈ Π‘Π¦Π–, супСринфСкция ΠœΠ‘Π’

    ВлияниС комплСкса Ρ…ΠΈΡ‚ΠΎΠ·Π°Π½-ß-циклодСкстрин с лСвофлоксацином Π½Π° ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρƒ Ρ€Π°Π½ ΠΈ толстого ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΈΠΊΠ° осСтра

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    The authors in the article presented the results of determining the effectiveness of using the chitosan-ß-cyclodextrin complex with levofloxacin in the healing of mechanical wounds of valuable commercial fish sturgeons and their feeding. The experiment was conducted based on the β€œProgressive biotechnologies in aquaculture” research laboratory of the Saratov State University of Genetics, Biotechnology and Engineering. N.I. Vavilov. The microflora of incised wounds and the large intestine of sturgeon fingerlings under the influence of fluoroquinolone, represented by levofloxacin based on cyclodextrin, included in the shell of high-molecular chitosan, was studied. The studied microbiological indicators were chosen to determine that changes in the total number of microorganisms show the nature of the course of the inflammatory/pathological process, which contributes to the development of microorganisms (including opportunistic pathogens) and lactic acid bacteria in the intestine. Therefore, they are essential physiological indicators of the formation of β€œ intestinal immunity. It was found that the use of cyclodextrin with levofloxacin in the treatment of incised wounds in sturgeons leads to a significant decrease in the total microbial number (TMC) on their surface (by 10 thousand times compared to the group without treatment). It has been shown that using cyclodextrin with levofloxacin in feeding sturgeons reduces the total microbial number in the large intestine. This complex is characterised by good solubility and bioavailability for fish. The future study results can be used in aquaculture to treat mechanical injuries received during transportation and sorting in the rearing process in fish.ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Ρ‹ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ опрСдСлСния эффСктивности примСнСния комплСкса Ρ…ΠΈΡ‚ΠΎΠ·Π°Π½-ß-циклодСкстрин с лСвофлоксацином Π² Π·Π°ΠΆΠΈΠ²Π»Π΅Π½ΠΈΠΈ мСханичСских Ρ€Π°Π½ Ρ†Π΅Π½Π½Ρ‹Ρ… промысловых Ρ€Ρ‹Π± – осСтров ΠΈ ΠΈΡ… ΠΊΠΎΡ€ΠΌΠ»Π΅Π½ΠΈΠΈ. ЭкспСримСнт ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ Π½Π° Π±Π°Π·Π΅ Π½Π°ΡƒΡ‡Π½ΠΎ-ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΡΠΊΠΎΠΉ Π»Π°Π±ΠΎΡ€Π°Ρ‚ΠΎΡ€ΠΈΠΈ Β«ΠŸΡ€ΠΎΠ³Ρ€Π΅ΡΡΠΈΠ²Π½Ρ‹Π΅ Π±ΠΈΠΎΡ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π² Π°ΠΊΠ²Π°ΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Π΅Β» Баратовского государствСнного унивСрситСта Π³Π΅Π½Π΅Ρ‚ΠΈΠΊΠΈ, Π±ΠΈΠΎΡ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈ ΠΈΠ½ΠΆΠ΅Π½Π΅Ρ€ΠΈΠΈ ΠΈΠΌ. Н.И. Π’Π°Π²ΠΈΠ»ΠΎΠ²Π°. ИсслСдовалась ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Π° Ρ€Π΅Π·Π°Π½Ρ‹Ρ… Ρ€Π°Π½ ΠΈ толстого ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΈΠΊΠ° сСголСтков осСтров ΠΏΠΎΠ΄ дСйствиСм Ρ„Ρ‚ΠΎΡ€Ρ…ΠΈΠ½ΠΎΠ»ΠΎΠ½Π°, прСдставлСнного лСвофлоксацином Π½Π° основС циклодСкстрина, Π²ΠΊΠ»ΡŽΡ‡Π΅Π½Π½ΠΎΠ³ΠΎ Π² ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΡƒ высокомолСкулярного Ρ…ΠΈΡ‚ΠΎΠ·Π°Π½Π°. Π˜ΡΡΠ»Π΅Π΄ΡƒΠ΅ΠΌΡ‹Π΅ микробиологичСскиС ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ Π±Ρ‹Π»ΠΈ Π²Ρ‹Π±Ρ€Π°Π½Ρ‹ для опрСдСлСния Π½Π° Ρ‚ΠΎΠΌ основании, Ρ‡Ρ‚ΠΎ измСнСния ΠΎΠ±Ρ‰Π΅Π³ΠΎ количСства ΠΌΠΈΠΊΡ€ΠΎΠΎΡ€Π³Π°Π½ΠΈΠ·ΠΌΠΎΠ² ΠΏΠΎΠΊΠ°Π·Ρ‹Π²Π°ΡŽΡ‚ Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ тСчСния Π²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ/патологичСского процСсса, ΡΠΏΠΎΡΠΎΠ±ΡΡ‚Π²ΡƒΡŽΡ‰Π΅Π³ΠΎ Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΡŽ ΠΌΠΈΠΊΡ€ΠΎΠΎΡ€Π³Π°Π½ΠΈΠ·ΠΌΠΎΠ² (Π² Ρ‚.Ρ‡. условно-ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π½Ρ‹Ρ…) ΠΈ молочнокислых Π±Π°ΠΊΡ‚Π΅Ρ€ΠΈΠΉ Π² ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΈΠΊΠ΅, поэтому ΡΠ²Π»ΡΡŽΡ‚ΡΡ Π²Π°ΠΆΠ½Ρ‹ΠΌΠΈ физиологичСскими показатСлями формирования Β«ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΎΠ³ΠΎ ΠΈΠΌΠΌΡƒΠ½ΠΈΡ‚Π΅Ρ‚Π°Β». Π‘Ρ‹Π»ΠΎ ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½ΠΎ, Ρ‡Ρ‚ΠΎ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΏΡ€ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Ρ€Π΅Π·Π°Π½Ρ‹Ρ… Ρ€Π°Π½ Ρƒ осСтров циклодСкстрина с лСвофлоксацином ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΌΡƒ ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΡŽ ΠΎΠ±Ρ‰Π΅Π³ΠΎ ΠΌΠΈΠΊΡ€ΠΎΠ±Π½ΠΎΠ³ΠΎ числа (ОМЧ) Π½Π° ΠΈΡ… повСрхности (Π² 10 тыс. Ρ€Π°Π· ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с Π³Ρ€ΡƒΠΏΠΏΠΎΠΉ Π±Π΅Π· лСчСния). Показано, Ρ‡Ρ‚ΠΎ использованиС Π² ΠΊΠΎΡ€ΠΌΠ»Π΅Π½ΠΈΠΈ осСтров циклодСкстрина с лСвофлоксацином Ρ‚Π°ΠΊΠΆΠ΅ сниТаСт ΠΎΠ±Ρ‰Π΅Π΅ ΠΌΠΈΠΊΡ€ΠΎΠ±Π½ΠΎΠ΅ число Π² толстом ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΈΠΊΠ΅. Π”Π°Π½Π½Ρ‹ΠΉ комплСкс характСризуСтся Ρ…ΠΎΡ€ΠΎΡˆΠ΅ΠΉ Ρ€Π°ΡΡ‚Π²ΠΎΡ€ΠΈΠΌΠΎΡΡ‚ΡŒΡŽ ΠΈ Π±ΠΈΠΎΠ΄ΠΎΡΡ‚ΡƒΠΏΠ½ΠΎΡΡ‚ΡŒΡŽ для Ρ€Ρ‹Π±. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ исслСдования Π² пСрспСктивС ΠΌΠΎΠ³ΡƒΡ‚ Π½Π°ΠΉΡ‚ΠΈ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π² Π°ΠΊΠ²Π°ΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Π΅ ΠΏΡ€ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ мСханичСских Ρ‚Ρ€Π°Π²ΠΌ, ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Ρ… ΠΏΡ€ΠΈ ΠΏΠ΅Ρ€Π΅Π²ΠΎΠ·ΠΊΠ΅ ΠΈ сортировкС Π² процСссС выращивания, Ρƒ Ρ€Ρ‹Π±
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