6,717 research outputs found

    Communications Biophysics

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    Contains reports on six research projects.National Science Foundation (Grant G-16526)National Institutes of Health (Grant MH-04737-02

    Behaviour Tracking: Using geospatial and behaviour sequence analysis to map crime

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    Crime is a complex phenomenon. To understand the commission of crime, researchers must map both the temporal and the spatial processes involved. The current research combines a temporal method of analysis, Behaviour Sequence Analysis, with geospatial mapping, to outline a new method of integrating temporal and spatial movements of criminals. To show how the new method can be applied, a burglary scenario was used, and the movements and behaviours of a criminal tracked around the property. Results showed that combining temporal and spatial analyses allows for a clearer account of the process of a crime scene. The current method has application to a large range of other crimes and terrorist movements, for instance between cities and movements within each city. Therefore, the current research provides the foundation framework for a novel method of spatio-temporal analyses of crime

    Superstructure and Correlated Na+ Hopping in a Layered Mg-Substituted Sodium Manganate Battery Cathode are Driven by Local Electroneutrality

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    Acknowledgments ARTICLE SECTIONSJump To E.N.B. acknowledges funding from the Engineering Physical Sciences Research Council (EPSRC) via the National Productivity Interest Fund (NPIF) 2018 (EP/S515334/1). J.D.B. acknowledges funding from the Faraday Institution (EP/S003053/1, FIRG016). The authors also thank the Science and Technology Facilities Council (STFC) and ISIS Neutron and Muon source for neutron data (experiment no.: RB2010350). Additional thanks are given to the staff scientists at beamline I11 of the Diamond Light Source for synchrotron data using block allocation group time under proposal CY34243. This work also utilized the ARCHER UK National Supercomputing Service via our membership in the UK’s HEC Materials Chemistry Consortium, funded by the EPSRC (EP/L000202). The research was also carried out at the Center for Functional Nanomaterials, Brookhaven National Laboratory, through the U.S. Department of Energy, Office of Basic Energy Sciences, Contract DE-AC02-98CH10866. E.N.B. would also like to thank A. Van der Ven and M.A. Jones for illuminating discussions.Peer reviewedPublisher PD

    Chameleons in the early universe: kicks, rebounds, and particle production

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    Chameleon gravity is a scalar-tensor theory that includes a nonminimal coupling between the scalar field and the matter fields and yet mimics general relativity in the Solar System. The scalar degree of freedom is hidden in high-density environments because the effective mass of the chameleon scalar depends on the trace of the stress-energy tensor. In the early Universe, when the trace of the matter stress-energy tensor is nearly zero, the chameleon is very light, and Hubble friction prevents it from reaching the minimum of its effective potential. Whenever a particle species becomes nonrelativistic, however, the trace of the stress-energy tensor is temporarily nonzero, and the chameleon begins to roll. We show that these “kicks” to the chameleon field have catastrophic consequences for chameleon gravity. The velocity imparted to the chameleon by the kick is sufficiently large that the chameleon’s mass changes rapidly as it slides past its potential minimum. This nonadiabatic evolution shatters the chameleon field by generating extremely high-energy perturbations through quantum particle production. If the chameleon’s coupling to matter is slightly stronger than gravitational, the excited modes have trans-Planckian momenta. The production of modes with momenta exceeding 107 GeV can only be avoided for small couplings and finely tuned initial conditions. These quantum effects also significantly alter the background evolution of the chameleon field, and we develop new analytic and numerical techniques to treat quantum particle production in the regime of strong dissipation. This analysis demonstrates that chameleon gravity cannot be treated as a classical field theory at the time of big bang nucleosynthesis and casts doubt on chameleon gravity’s viability as an alternative to general relativity

    Stagnation temperature measurement using thin-film platinum resistance sensors

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    The measurement of stagnation temperature in high-speed flows is an important aspect of gas turbine engine testing. The ongoing requirement to improve the accuracy of such measurements has led to the development of probe systems that use a thin-film platinum resistance thermometer (PRT) as the sensing element. For certain aspects of engine testing this type of sensing device potentially offers superior measurement performance to the thermocouple, the temperature sensor of choice in most gas turbine applications. This paper considers the measurement performance of prototype PRT-based stagnation temperature probes, up to high-subsonic flow conditions, using passively aspirated probe heads. The relatively poor temperature recovery performance of a simply constructed probe has led to the development of a new design that is intended to reduce the impact of thermal conduction within the probe assembly. The performance of this so-called dual-skin probe has been measured through a series of tests at a range of Mach numbers, incidence angles and Reynolds numbers. The data reveal that a high probe recovery factor has been achieved with this device, and that the application of this design to engine tests would yield the measurement performance benefits of the PRT whilst requiring small levels of temperature recovery compensation

    Combination probes for stagnation pressure and temperature measurements in gas turbine engines

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    During gas turbine engine testing, steady-state gas-path stagnation pressures and temperatures are measured in order to calculate the efficiencies of the main components of turbomachinery. These measurements are acquired using fixed intrusive probes, which are installed at the inlet and outlet of each component at discrete point locations across the gas-path. The overall uncertainty in calculated component efficiency is sensitive to the accuracy of discrete point pressures and temperatures, as well as the spatial sampling across the gas-path. Both of these aspects of the measurement system must be considered if more accurate component efficiencies are to be determined. High accuracy has become increasingly important as engine manufacturers have begun to pursue small gains in component performance, which require efficiencies to be resolved to within less than ±1%. This article reports on three new probe designs that have been developed in a response to this demand. The probes adopt a compact combination arrangement that facilitates up to twice the spatial coverage compared to individual stagnation pressure and temperature probes. The probes also utilise novel temperature sensors and high recovery factor shield designs that facilitate improvements in point measurement accuracy compared to standard Kiel probes used in engine testing. These changes allow efficiencies to be resolved within ±1% over a wider range of conditions than is currently achievable with Kiel probes

    Predictors and outcomes of crossover to surgery from physical therapy for meniscal tear and osteoarthritis a randomized trial comparing physical therapy and surgery

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    BACKGROUND: Arthroscopic partial meniscectomy (APM) combined with physical therapy (PT) have yielded pain relief similar to that provided by PT alone in randomized trials of subjects with a degenerative meniscal tear. However, many patients randomized to PT received APM before assessment of the primary outcome. We sought to identify factors associated with crossing over to APM and to compare pain relief between patients who had crossed over to APM and those who had been randomized to APM. METHODS: We used data from the MeTeOR (Meniscal Tear in Osteoarthritis Research) Trial of APM with PT versus PT alone in subjects ≥45 years old who had mild-to-moderate osteoarthritis and a degenerative meniscal tear. We assessed independent predictors of crossover to APM among those randomized to PT. We also compared pain relief at 6 months among those randomized to PT who crossed over to APM, those who did not cross over, and those originally randomized to APM. RESULTS: One hundred and sixty-four subjects were randomized to and received APM and 177 were randomized to PT, of whom 48 (27%) crossed over to receive APM in the first 140 days after randomization. In multivariate analyses, factors associated with a higher likelihood of crossing over to APM among those who had originally been randomized to PT included a baseline Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Score of ≥40 (risk ratio [RR] = 1.99; 95% confidence interval [CI] = 1.00, 3.93) and symptom duration of <1 year (RR = 1.74; 95% CI = 0.98, 3.08). Eighty-one percent of subjects who crossed over to APM and 82% of those randomized to APM had an improvement of ≥10 points in their pain score at 6 months, as did 73% of those who were randomized to and received only PT. CONCLUSIONS: Subjects who crossed over to APM had presented with a shorter symptom duration and greater baseline pain than those who did not cross over from PT. Subjects who crossed over had rates of surgical success similar to those of the patients who had been randomized to surgery. Our findings also suggest that an initial course of rigorous PT prior to APM may not compromise surgical outcome. LEVEL OF EVIDENCE: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence

    Trace Gas Emissions from Biomass Burning inferred from Aerosol Optical Depth

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    We have observed strong correlations between simultaneous and co-located measurements of aerosol optical depth and column amounts of carbon monoxide, hydrogen cyanide, formaldehyde and ammonia in bushfire smoke plumes over SE Australia during the Austral summers of 2001/2002 and 2002/2003. We show how satellite-derived aerosol optical depth maps may be used in conjunction with these correlations to determine the total amounts of these gases present in a fire-affected region. This provides the basis of a method for estimating total emissions of trace gases from biomass burning episodes using visible radiances measured by satellite
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