376 research outputs found

    More on the Tensor Response of the QCD Vacuum to an External Magnetic Field

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    In this Letter we discuss a few issues concerning the magnetic susceptibility of the quark condensate and the Son-Yamamoto (SY) anomaly matching equation. It is shown that the SY relation in the IR implies a nontrivial interplay between the kinetic and WZW terms in the chiral Lagrangian. It is also demonstrated that in a holographic framework an external magnetic field triggers mixing between scalar and tensor fields. Accounting for this, one may calculate the magnetic susceptibility of the quark condensate to all orders in the magnetic field.Comment: 20 pages, 2 figure

    Holographic quenches and fermionic spectral functions

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    Using holographic methods we investigate the behaviour of fermionic spectral functions of strongly coupled 2+1 dimensional field theories as both temperature and chemical potential are quenched

    Assembly of the Inner Perivitelline Layer, a Homo log of the Mammalian Zona Pellucida: An Immunohistochemical and Ultrastructural Study

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    The avian inner perivitelline layer (IPVL), a homologous structure to the mammalian zona pellucida, is deposited between the granulosa cells and the oocyte cell membrane during folliculogenesis. The glycoprotein meshwork of the IPVL forms a 3-dimensional matrix and possesses important functions in the fertilization process: it contributes to the binding of avian spermatozoa to the oocyte and induces acrosomal exocytosis. In contrast to the zona pellucida of mammals, the IPVL does not prevent the physiological polyspermy found in birds. Previous studies have shown that in the Japanese quail (Cotumix japonica) at least 5 glycoproteins are constituents of the IPVL (ZP1, ZP2, ZP3, ZP4, and ZPD). In this study, we investigated the spatiotennporal assembly pattern of the IPVL during folliculogenesis using immunohistochemical and ultrastructural methods. The obtained results clearly show that these glycoproteins are incorporated into the IPVL at distinct points during follicular development, supporting the hypothesis that ZP2 and ZP4 form a type of prematrix into which ZP1, ZP3, and ZPD are integrated at a later stage of development. Copyright (C) 2011 S. Karger AG, Base

    A Review of Magnetic Phenomena in Probe-Brane Holographic Matter

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    Gauge/gravity duality is a useful and efficient tool for addressing and studying questions related to strongly interacting systems described by a gauge theory. In this manuscript we will review a number of interesting phenomena that occur in such systems when a background magnetic field is turned on. Specifically, we will discuss holographic models for systems that include matter fields in the fundamental representation of the gauge group, which are incorporated by adding probe branes into the gravitational background dual to the gauge theory. We include three models in this review: the D3-D7 and D4-D8 models, that describe four-dimensional systems, and the D3-D7' model, that describes three-dimensional fermions interacting with a four-dimensional gauge field.Comment: 35 pages, 27 figures, to appear in Lect. Notes Phys. "Strongly interacting matter in magnetic fields" (Springer), edited by D. Kharzeev, K. Landsteiner, A. Schmitt, H.-U. Yee; references adde

    Inverse magnetic catalysis in field theory and gauge-gravity duality

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    We investigate the surface of the chiral phase transition in the three-dimensional parameter space of temperature, baryon chemical potential and magnetic field in two different approaches, the field-theoretical Nambu-Jona-Lasinio (NJL) model and the holographic Sakai-Sugimoto model. The latter is a top-down approach to a gravity dual of QCD with an asymptotically large number of colors and becomes, in a certain limit, dual to an NJL-like model. Our main observation is that, at nonzero chemical potential, a magnetic field can restore chiral symmetry, in apparent contrast to the phenomenon of magnetic catalysis. This "inverse magnetic catalysis" occurs in the Sakai-Sugimoto model and, for sufficiently large coupling, in the NJL model and is related to the physics of the lowest Landau level. While in most parts our discussion is a pedagogical review of previously published results, we include new analytical results for the NJL approach and a thorough comparison of inverse magnetic catalysis in the two approaches.Comment: 37 pages, 11 figures, to appear in Lect. Notes Phys. "Strongly interacting matter in magnetic fields" (Springer), edited by D. Kharzeev, K. Landsteiner, A. Schmitt, H.-U. Ye

    Holographic rho mesons in an external magnetic field

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    We study the rho meson in a uniform magnetic field eB using a holographic QCD-model, more specifically a D4/D8/Dbar8 brane setup in the confinement phase at zero temperature with two quenched flavours. The parameters of the model are fixed by matching to corresponding dual field theory parameters at zero magnetic field. We show that the up- and down-flavour branes respond differently to the presence of the magnetic field in the dual QCD-like theory, as expected because of the different electromagnetic charge carried by up- and down-quark. We discuss how to recover the Landau levels, indicating an instability of the QCD vacuum at eB = m_rho^2 towards a phase where charged rho mesons are condensed, as predicted by Chernodub using effective QCD-models. We improve on these existing effective QCD-model analyses by also taking into account the chiral magnetic catalysis effect, which tells us that the constituent quark masses rise with eB. This turns out to increase the value of the critical magnetic field for the onset of rho meson condensation to eB = 1.1 m_rho^2 = 0.67 GeV^2. We briefly discuss the influence of pions, which turn out to be irrelevant for the condensation in the approximation made.Comment: 26 pages, 10 .pdf figures, v2: version accepted for publication in JHE

    The emerging structure of the Extended Evolutionary Synthesis: where does Evo-Devo fit in?

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    The Extended Evolutionary Synthesis (EES) debate is gaining ground in contemporary evolutionary biology. In parallel, a number of philosophical standpoints have emerged in an attempt to clarify what exactly is represented by the EES. For Massimo Pigliucci, we are in the wake of the newest instantiation of a persisting Kuhnian paradigm; in contrast, Telmo Pievani has contended that the transition to an EES could be best represented as a progressive reformation of a prior Lakatosian scientific research program, with the extension of its Neo-Darwinian core and the addition of a brand-new protective belt of assumptions and auxiliary hypotheses. Here, we argue that those philosophical vantage points are not the only ways to interpret what current proposals to ‘extend’ the Modern Synthesis-derived ‘standard evolutionary theory’ (SET) entail in terms of theoretical change in evolutionary biology. We specifically propose the image of the emergent EES as a vast network of models and interweaved representations that, instantiated in diverse practices, are connected and related in multiple ways. Under that assumption, the EES could be articulated around a paraconsistent network of evolutionary theories (including some elements of the SET), as well as models, practices and representation systems of contemporary evolutionary biology, with edges and nodes that change their position and centrality as a consequence of the co-construction and stabilization of facts and historical discussions revolving around the epistemic goals of this area of the life sciences. We then critically examine the purported structure of the EES—published by Laland and collaborators in 2015—in light of our own network-based proposal. Finally, we consider which epistemic units of Evo-Devo are present or still missing from the EES, in preparation for further analyses of the topic of explanatory integration in this conceptual framework

    Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome

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    Transcription and pre-mRNA splicing are the key nuclear processes in eukaryotic gene expression, and identification of factors common to both processes has suggested that they are functionally coordinated. p100 protein has been shown to function as a transcriptional co-activator for several transcription factors. p100 consists of staphylococcal nuclease (SN)-like and Tudor-SN (TSN) domains of which the SN-like domains have been shown to function in transcription, but the function of TSN domain has remained elusive. Here we identified interaction between p100 and small nuclear ribonucleoproteins (snRNP) that function in pre-mRNA splicing. The TSN domain of p100 specifically interacts with components of the U5 snRNP, but also with the other spliceosomal snRNPs. In vitro splicing assays revealed that the purified p100, and specifically the TSN domain of p100, accelerates the kinetics of the spliceosome assembly, particularly the formation of complex A, and the transition from complex A to B. Consistently, the p100 protein, as well as the separated TSN domain, enhanced the kinetics of the first step of splicing in an in vitro splicing assay in dose-dependent manner. Thus our results suggest that p100 protein is a novel dual function regulator of gene expression that participates via distinct domains in both transcription and splicing
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