325 research outputs found

    The Nidar Ophiolite and its surrounding units in the Indus Suture Zone (NW Himalaya, India): new field data and interpretations

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    The Nidar Ophiolite is located between the North Himalayan nappes and the Indus Suture Zone in NW Himalaya in eastern Ladakh (India). Based mainly on geochemical argument, this ophiolite is classically interpreted as a relic of an intra-oceanic arc (Mahéo et al. 2000; Mahéo et al. 2004), which developed at around 140 Ma, prior to the collision between the Indian and Eurasian plates (Ahmad et al. 2008). From top to bottom, this ophiolite is composed of various sedimentary rocks (radiolarites, polygenic conglomerates and carbonates), volcanic rocks (pillow lavas, basaltic to andesitic in composition), gabbros (Fe- and layered gabbros, pegmatites and minor troctolites), serpentinites, dunites, pyroxenites and peridotites (mainly harzburgites). The Nidar Ophiolite underwent an anchizonal metamorphism with preservation of primaries structures (layering) and volcanic textures (pillow lavas). This study is mainly focused on new field observations across the ophiolite and the surrounding units. A new detailed geologic map of the ophiolite between the Nidar village and Kyun Tso area is presented. The upper part of the ophiolitic complex is an alternation of volcanic and sedimentary rocks (500- 1000 m thick) and the lower part consists of large outcrops of gabbros (3000m thick). These mafic rocks are separated from the serpentinized ultramafic rocks by a 200m thick ophiolitic breccia and continental Indus Molasse slices. The Nidar Ophiolite is made up of the classical rock type succession (ultramafites, gabbros, pillow basalts, radiolarites), but the internal structure is far more complex than previously suggested. New field data (geologic and structural maps, lithologic sections, etc.) coupled with new geochemical analysis will help to constrain the geodynamic context and deformation history. Ahmad, T., T. Tanaka, H.K. Sachan, Y. Asahara, R. Islam, et P.P. Khanna. 2008. « Geochemical and isotopic constraints on the age and origin of the Nidar Ophiolitic Complex, Ladakh, India: Implications for the Neo-Tethyan subduction along the Indus suture zone ». Tectonophysics 451 (1–4): 206‑ 24. Mahéo, Gweltaz, Hervé Bertrand, Stéphane Guillot, Georges Mascle, Arnaud Pêcher, Christian Picard, et Julia De Sigoyer. 2000. « Témoins d’un arc immature téthysien dans les ophiolites du Sud Ladakh (NW Himalaya, Inde) ». Comptes Rendus de l’Académie des Sciences - Series IIA - Earth and Planetary Science 330 (4): 289‑ 95. Mahéo, Gweltaz, Hervé Bertrand, Stéphane Guillot, Igor M. Villa, Francine Keller, et Paul Capiez. 2004. « The South Ladakh ophiolites (NW Himalaya, India): an intra-oceanic tholeiitic arc origin with implication for the closure of the Neo-Tethys ». Chemical Geology 203 (3–4): 273‑ 303

    Optimizing electrode implantation in sacral nerve stimulation—an anatomical cadaver study controlled by a laparoscopic camera

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    Background and aim: Sacral nerve stimulation is the therapy of choice in patients with neurogenic faecal and urine incontinence, constipation and some pelvic pain syndromes. The aim of this study is to determine the best insertion angles of the electrode under laparoscopic visualization of the sacral nerves. Materials and methods: Five fresh cadaver pelvises were dissected through an anterior approach of the presacral space, exposing the ventral sacral roots. Needles and electrodes were inserted into the S3 foramen. Both right and left sides were used, with the traditional percutaneous procedure. The validation was done by a laparoscopic camera controlling the position of the needle and electrode on the nerve. The angles were assessed with a goniometer and were confirmed in two living patients. Results: The mean angle of insertion in the sagittal plane was 62.9 ± 3° (range, 59-70). In the axial plane, the mean angle for the left side was 91.7 ± 13.5° (range, 80-110) and 83.2 ± 7.7° for the right side (range, 75-95). These angles resulted in the optimal placement of the leads along the S3 sacral root, in all these cases. Conclusions: This study allows direct visualization during the placement of the needle and electrode, thus permitting accurate calculations of the best angle of approach during the surgical procedure in sacral nerve stimulation. These objective findings attempt to standardize this technique, which is often performed with the aid of intra-operative fluoroscopy but still leaving a lot to chance. These insertion angles should help to find more consistent and reproducible results and thus improved outcome in patient

    An Ecological Basic Income? Examining the Ecological Credentials of Basic Income Through a Review of Selected Pilot Interventions

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    While basic income (BI) has long been advocated for its social benefits, some scholars also propose it in response to the ecological crises. However, the empirical evidence to support this position is currently lacking and the concept of an ecological BI (EBI) is underdeveloped. Part one of this paper attempts to develop such a concept, arguing that an EBI should seek to reduce aggregate material throughput, improve human needs satisfaction, reduce inequalities, rebalance productive activity towards social activities in the autonomous sphere, and promote societal values of cooperation and sufficiency. Part two examines how BI interventions consider the principles of an EBI in their designs and discusses what their findings infer about BI’s ecological credentials. The results find that while ecological considerations are largely absent from BI intervention designs, their findings suggest that interventions aligned with the principles of an EBI could play a role in addressing the ecological crises

    Ophiolites in the North Himalayan nappes and Indus Suture Zone in Eastern Ladakh (NW Himalaya, India)

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    Ophiolites are fragments of ancient oceanic lithosphere, preserved in orogenic belts in a context of plate convergence. They are generated at mid-ocean ridges, in a supra-subduction zone or volcanic arc. Commonly, several magmatic events are recorded, as shown, for instance, in the Oman Ophiolite (Goodenough et al. 2014). The Ophiolitic rocks of Eastern Ladakh are subdivided in two main groups, based on the geodynamic setting during their formation: the supra-subduction zone ophiolite and the ophiolitic “mélanges”, corresonding both to the Indus Suture Zone. Recent detailed studies North-East of the Tso Moriri area revealed a large diversity of ophiolitic rocks and associated sediments. We identified three distinct tectonic units containing ophiolites: The Nidar Ophiolite, the Drakkarpo nappe and the Karzok-Ribil nappe. The Nidar supra-subduction zone Ophiolite represents a complete ophiolitic sequence, from mantle to sediments, which underwent a low greenschist facies metamorphism. This ophiolitic sequence was thrusted towards the South. They record a first magmatic event in a mid-ocean ridge setting, and a second one in a supra-subduction zone at around 130 Ma. The Drakkarpo nappe is a “mélange” unit composed of thick polygenic conglomerates and volcano-sedimentary rocks, mainly composed of tuffs and augite-basalts (OIB), serpentinites, pillow lavas and gabbros. This unit is interpreted as being a part of an accretionary wedge containing slices of oceanic islands arc. This nappe marks the Indus Suture Zone. The Karzok-Ribil nappe is a newly defined tectonic unit involved in the North Himalayan nappe stack. It can be followed at the top of the Tetraogal nappe and around the Tso Morari dome. The Karzok-Ribil nappe is composed of segments of ophiolitic sequence (serpentinites, gabbros, pillow lavas), radiolarites, polygenic conglomerates, agglomeratic slates from the indian margin, augite-basalts (OIB) and limestones. It is interpreted as being originally a seamount, located close to the Indian passive margin in a ocean-continent transition zone. The new lithostratigraphy and structural analyses of the Eastern Ladakh ophiolites and their associated sediments allow us to better constrain the formation and emplacement mechanisms of these tectonic units. It defines or precises the paleogeography and geometry of the north Indian passive margin, prior to the Himalayan collision. REFERENCES Goodenough, Kathryn M., Robert J. Thomas, Michael T. Styles, David I. Schofield, and Christopher J. MacLeod. 2014. “Records of Ocean Growth and Destruction in the Oman–UAE Ophiolite.” Elements 10 (2): 109–114

    Geology of the eastern part of the Tso Morari nappe, the Nidar Ophiolite and the surrounding tectonic units (NW Himalaya, India)

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    The Tso Morari nappe is well known for having suffered ultrahigh-pressure metamorphism in the northwest Himalaya. Its pressure-temperature evolution has been widely studied and debated since the end of the 1990s. However, the lithostratigraphy, structures and metamorphism of the tectonic units around the Tso Morari nappe are poorly known, especially in the eastern part of the nappe. Here, a detailed geologic map based on recent field work is presented. The survey area is the eastern part of the ultrahigh-pressure Tso Morari nappe, the surrounding tectonic units and the Nidar Ophiolite. This map improves the knowledge of the geology and geometry of the North Indian continental plate and the ocean-derived units south of the Eurasian continent in eastern Ladakh. Knowledge of the present-day geometry will help to reconstruct the initial setting in the kinematic models of the formation and exhumation of the Tso Morari nappe in relation to its surrounding tectonic units

    Risk factors for mortality-morbidity after emergency-urgent colorectal surgery

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    Background: The aim of this study was to assess the risk factors associated with mortality and morbidity following emergency or urgent colorectal surgery. Materials and methods: All data regarding the 462 patients who underwent emergency colonic resection in our institution between November 2002 and December 2007 were prospectively entered into a computerized database. Results: The median age of patients was 73 (range 17-98)years. The most common indications for surgery were: 171 adenocarcinomas (37%), 129 complicated diverticulitis (28%), and 35 colonic ischemia (7.5%). Overall mortality and morbidity rates were 14% and 36%, respectively. In multivariate analysis, the only parameter significantly associated with postoperative mortality was blood loss >500cm3 (odds ratio (OR) = 3.33, 95% confidence interval (CI) 1.63-6.82, p = 0.001). There were three parameters which correlated with postoperative morbidity: ASA score ≥3 (OR = 2.9, 95% CI 1.9-4.5, p < 0.001), colonic ischemia (OR = 3.4, 95% CI 1.4-7.7, p = 0.006), and stoma creation (OR = 2.2, 95% CI 1.4-3.4, p = 0.0003). Conclusions: The main risk factors for postoperative morbidity and mortality following emergency colorectal surgery are related to: (1) patients' ASA score, (2) colonic ischemia, and (3) perioperative bleeding. These variables should be considered in the elaboration of future scoring systems to predict outcome of emergency colorectal surger

    Markers of bone turnover for the management of patients with bone metastases from prostate cancer

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    Although increased bone formation is a prominent feature of patients with osteosclerotic metastases from prostate cancer, there is also some evidence for increased bone resorption. The aim of this study was to compare the clinical utility of new bone resorption markers to that of bone formation in patients with bone metastases from prostate cancer before and after bisphosphonate treatment. Thirty-nine patients with prostate cancer and bone metastasis, nine patients with prostate cancer without bone metastases, nine patients with benign prostatic hyperplasia and 355 healthy age-matched men were included. Urinary non-isomerized (α CTX) and β isomerized (β CTX) type I collagen C-telopeptides (CTX) and a new assay for serum CTX were used to assess bone resorption. Bone formation was determined by serum osteocalcin, serum total (T-ALP) and bone (BAP) alkaline phosphatase and serum type I collagen C-terminal propeptide (PICP). Fourteen patients with bone metastases were also evaluated 15 days after a single injection of the bisphosphonate pamidronate (120 mg). Levels of all bone formation and bone resorption markers were significantly (P< 0.006–0.0001) higher in patients with prostate cancer and bone metastasis than in patients with benign prostatic hyperplasia, patients with prostate cancer without bone metastases and healthy controls. In patients with bone metastases the median was increased by 67% for serum osteocalcin, 128% for T-ALP, 138% for BAP, 79% for PICP, 220% for urinary α CTX, 149% for urinary β CTX and 214% for serum CTX. After bisphosphonate treatment all three resorption markers significantly decreased by an average of 65% (P = 0.001), 71% (P = 0.0010) and 61% (P = 0.0015) for urinary α CTX, urinary β CTX and serum CTX, respectively, whereas no significant change was observed for any bone formation markers. Patients with prostate cancer and bone metastases exhibit a marked increase in bone resorption, which decreases within a few days of treatment with pamidronate. These findings suggest that these new resorption markers may be useful for the management of these patients. © 2000 Cancer Research Campaig
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