2,126 research outputs found
Site occupation constraints in mean-field approaches of quantum spin systems at finite temperature
We study the effect of site occupation on the description of quantum spin
systems at finite temperature and mean-field level. We impose each lattice site
to be occupied by a single electron. This is realized by means of a specific
prescription. The outcome of the prescription is compared to the result
obtained by means of a projection procedure which fixes the site occupation to
one particle per site on an average. The comparison is performed for different
representations of the Hamiltonian in Fock space leading to different types of
mean-field solutions. The behaviour of order parameters is analyzed for each
choice of the mean-field and constraint which fixes the occupation rate at each
site. Sizable quantitative differences between the outcomes obtained with the
two different constraints are observed.Comment: 18 pages, 2 figure
Analysis of chronic rejection and obliterative arteriopathy: Possible contributions of donor antigen-presenting cells and lymphatic disruption
Sequential analysis of changes that lead to chronic rejection was undertaken in an animal model of chronic rejection and obliterative arteriopathy. Brown Norway rats are pretreated with a Lewis bone marrow infusion or a Lewis orthotopic liver allograft and a short course of immunosuppression. They are challenged 100 days later with a Lewis heterotopic heart graft without immunosuppression. The heart grafts in both groups undergo a transient acute rejection, but all rats are operationally tolerant; the heart grafts are accepted and remain beating for more than 100 days. Early arterial remodeling, marked by arterial bromodeoxyuridine incorporation, occurred in both groups between 5 and 30 days during the transient acute rejection. It coincided with the presence of interstitial (but not arterial intimal) inflammation and lymphatic disruption and resulted in mild intimal thickening. Significant arterial narrowing occurred only in the bone-marrow-pretreated rats between 60 and 100 days. It was associated with T lymphocyte and macrophage inflammation of the heart graft that accumulated in the endocardium and arterial intima and adventitia near draining lymphatics. There also was loss of passenger leukocytes from the heart graft, up-regulation of cytokine mRNA and major histocompatibility class II on the endothelium, and focal disruption of lymphatics. In contrast, long-surviving heart grafts from the Lewis orthotopic liver allograft pretreated group are near normal and freedom from chronic rejection in this group was associated with persistence of donor major histocompatibility class-II-positive hematolymphoid cells, including OX62+ donor dendritic cells. This study offers insights into two different aspects of chronic rejection: 1) possible mechanisms underlying the persistent immunological injury and 2) the association between immunological injury and the development of obliterative arteriopathy. Based on the findings, it is not unreasonable to raise the testable hypothesis that direct presentation of alloantigen by donor antigen-presenting cells is required for long-term, chronic-rejection-free allograft acceptance. In addition, chronic intermittent lymphatic disruption is implicated as a possible mechanism for the association between chronic interstitial allograft inflammation and the development of obliterative arteriopathy
On the reliability of negative heat capacity measurements
A global protocol for the thermostatistical analysis of hot nuclear sources
is discussed. Within our method of minimization of variances we show that the
abnormal kinetic energy fluctuation signal recently reported in different
experimental data (M.D'Agostino et al.-Phys. Lett. B 473 (2000) 219, N. Le
Neindre et al.- contr. to the XXXVIII Bormio Winter Meeting on Nucl. Phys.
(2001) 404) is a genuine signal of a first order phase transition in a finite
system.Comment: 15 Postscript figures, submitted to NUCL. Phys. A on 24-apr-200
Finite size effects and the order of a phase transition in fragmenting nuclear systems
We discuss the implications of finite size effects on the determination of
the order of a phase transition which may occur in infinite systems. We
introduce a specific model to which we apply different tests. They are aimed to
characterise the smoothed transition observed in a finite system. We show that
the microcanonical ensemble may be a useful framework for the determination of
the nature of such transitions.Comment: LateX, 5 pages, 5 figures; Fig. 1 change
Topologically disordered systems at the glass transition
The thermodynamic approach to the viscosity and fragility of amorphous oxides was used to determine the topological characteristics of the disordered network-forming systems. Instead of the disordered system of atoms we considered the congruent disordered system of interconnecting bonds. The Gibbs free energy of network-breaking defects (configurons) was found based on available viscosity data. Amorphous silica and germania were used as reference disordered systems for which we found an excellent agreement of calculated and measured glass transition temperatures. We reveal that the Hausdorff dimension of the system of bonds changes from Euclidian three-dimensional below to fractal 2.55 ± 0.05-dimensional geometry above the glass transition temperature
Dynamical heterogeneities in a supercooled Lennard-Jones liquid
We present the results of a large scale molecular dynamics computer
simulation study in which we investigate whether a supercooled Lennard-Jones
liquid exhibits dynamical heterogeneities. We evaluate the non-Gaussian
parameter for the self part of the van Hove correlation function and use it to
identify ``mobile'' particles. We find that these particles form clusters whose
size grows with decreasing temperature. We also find that the relaxation time
of the mobile particles is significantly shorter than that of the bulk, and
that this difference increases with decreasing temperature.Comment: 8 pages of RevTex, 4 ps figure
The significance of macrophage phenotype in cancer and biomaterials
Macrophages have long been known to exhibit heterogeneous and plastic phenotypes. They show functional diversity with roles in homeostasis, tissue repair, immunity and disease. There exists a spectrum of macrophage phenotypes with varied effector functions, molecular determinants, cytokine and chemokine profiles, as well as receptor expression. In tumor microenvironments, the subset of macrophages known as tumor-associated macrophages generates byproducts that enhance tumor growth and angiogenesis, making them attractive targets for anti-cancer therapeutics. With respect to wound healing and the foreign body response, there is a necessity for balance between pro-inflammatory, wound healing, and regulatory macrophages in order to achieve successful implantation of a scaffold for tissue engineering. In this review, we discuss the multitude of ways macrophages are known to be important in cancer therapies and implanted biomaterials
Estimate of average freeze-out volume in multifragmentation events
An estimate of the average freeze-out volume for multifragmentation events is
presented. Values of volumes are obtained by means of a simulation using the
experimental charged product partitions measured by the 4pi multidetector INDRA
for 129Xe central collisions on Sn at 32 AMeV incident energy. The input
parameters of the simulation are tuned by means of the comparison between the
experimental and simulated velocity (or energy) spectra of particles and
fragments.Comment: To be published in Phys. Lett. B 12 pages, 5 figure
First measurement of production in pp collisions at = 7 TeV
The production of the charm-strange baryon is measured for
the first time at the LHC via its semileptonic decay into e
in pp collisions at TeV with the ALICE detector. The transverse
momentum () differential cross section multiplied by the branching
ratio is presented in the interval 1 8 GeV/ at
mid-rapidity, 0.5. The transverse momentum dependence of the
baryon production relative to the D meson production is
compared to predictions of event generators with various tunes of the
hadronisation mechanism, which are found to underestimate the measured
cross-section ratio.Comment: 22 pages, 6 captioned figures, 1 table, authors from page 17,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/412
- âŠ