Goods and Services Tax- A Critical Analysis

The paper is about the biggest tax reform that our India went through as the tax structure has become now direct which was lately indirect since ages, this paper will introduce this indirect tax structure through different explanations, and will explain the principle behind GST Bill which was placed in parliament through122nd Constitutional amendment. What was a non- GST regime and how will GST function with the salient features of GST and the advantages with the lacunae in it. Concerns which come with the GST Act has also been discussed further with more emphasis led on the vital 122nd amendment made in Indian Constitution

Dyeing of cotton with sulphur dyes using alkaline catalase as reduction catalyst

Attempts have been made to dye cotton with alkaline catalase to observe if sodium sulphide can be replaced with it. It is observed that the alkaline catalase is too capable of developing comparable dyebath potential, dye receptivity on cotton, reduction bath stability as well as colourfastness of dyeings as obtained in sodium sulphide based reducing systems

Cysticercus antibodies and antigens in serum from blood donors from Pondicherry, India

The aim of the present study was to screen the serum of blood donors, which are apparently healthy and residing in Pondicherry or its neighboring districts of Tamil Nadu State, for specific detection of Cysticercus antigens and antibodies. A total of 216 blood samples were collected from blood donors at the Central Blood Bank, JIPMER Hospital, Pondicherry, India during January and February 2004. Enzyme-linked immunosorbent assay (ELISA) was used to demonstrate anti-Cysticercus antibodies and the Co-agglutination (CoA) was used to detect antigen in sera. 14 (6.48 %) males were positive for either anti-Cysticercus antibodies or antigens. Of these eight sera were positive for anti-Cysticercus antibodies and six were positive for antigens. Results of the present study show that serum Cysticercus antigen detection may be a useful adjunct to antibody testing for seroprevalence studies of cysticercosis in the community. The present study is the first kind of study, carried out to determine both cysticercal antibodies as well as antigens in the serum samples collected from the healthy blood donors.O objetivo do presente estudo foi examinar o soro de doadores de sangue que são aparentemente saudáveis e residentes em Pondicherry ou seus distritos vizinhos do estado de Tamil Nadu, para a detecção específica dos antígenos e anticorpos de Cysticercus. Um total de 216 amostras de sangue foram coletadas de doadores de sangue do "Central Blood Bank, JIPMER Hospital", Pondicherry, Índia, durante janeiro e fevereiro de 2004. ELISA foi usado para demonstrar anticorpos anti-Cysticercus e co-aglutinação (CoA) foi utilizada para detectar antígenos no soro. 14 (6.48%) homens foram positivos para antígenos e anticorpos anti-Cysticercus. Destes, oito soros foram positivos para anticorpos anti-Cysticercus e seis positivos para antígenos. Os resultados do presente estudo mostram que a detecção de antígenos de Cysticercus no soro pode ser um adjunto útil para o teste de anticorpos para estudos de soroprevalência de cisticercose na comunidade. O presente estudo é o primeiro do tipo, realizado para determinar tanto anticorpos de Cysticercus como antígenos nas amostras de soro coletadas de doadores de sangue aparentemente saudáveis

Increased risk of HIV and other drug-related harms associated with injecting in public places: national bio-behavioural survey of people who inject drugs

Background: Whilst injecting drugs in public places is considered a proxy for high risk behaviour among people who inject drugs (PWID), studies quantifying its relationship with multiple drug-related harms are lacking and none have examined this in the context of an ongoing HIV outbreak (located in Glasgow, Scotland). We aimed to: 1) estimate the prevalence of public injecting in Scotland and associated risk factors; and 2) estimate the association between public injecting and HIV, current HCV, overdose, and skin and soft tissue infections (SSTI). Methods: Cross-sectional, bio-behavioural survey (including dried blood spot testing to determine HIV and HCV infection) of 1469 current PWID (injected in last 6 months) recruited by independent interviewers from 139 harm reduction services across Scotland during 2017–18. Primary outcomes were: injecting in a public place (yes/no); HIV infection; current HCV infection; self-reported overdose in the last year (yes/no) and SSTI the last year (yes/no). Multi-variable logistic regression was used to determine factors associated with public injecting and to estimate the association between public injecting and drug-related harms (HIV, current HCV, overdose and SSTI). Results: Prevalence of public injecting was 16% overall in Scotland and 47% in Glasgow city centre. Factors associated with increased odds of public injecting were: recruitment in Glasgow city centre (aOR=5.45, 95% CI 3.48–8.54, p<0.001), homelessness (aOR=3.68, 95% CI 2.61–5.19, p<0.001), high alcohol consumption (aOR=2.42, 95% CI 1.69–3.44, p<0.001), high injection frequency (≥4 per day) (aOR=3.16, 95% CI 1.93–5.18, p<0.001) and cocaine injecting (aOR=1.46, 95% CI 1.00 to 2.13, p = 0.046). Odds were lower for those receiving opiate substitution therapy (OST) (aOR=0.37, 95% CI 0.24 to 0.56, p<0.001) and older age (per year increase) (aOR=0.97, 95% CI 0.95 to 0.99, p = 0.013). Public injecting was associated with an increased risk of HIV infection (aOR=2.11, 95% CI 1.13–3.92, p = 0.019), current HCV infection (aOR=1.49, 95% CI 1.01–2.19, p = 0.043), overdose (aOR=1.59, 95% CI 1.27–2.01, p<0.001) and SSTI (aOR=1.42, 95% CI 1.17–1.73, p<0.001). Conclusions: These findings highlight the need to address the additional harms observed among people who inject in public places and provide evidence to inform proposals in the UK and elsewhere to introduce facilities that offer safer drug consumption environments

Correlation of Clinical Examination, MRI and Arthroscopy Findings in Menisco-Cruciate Injuries of the Knee: A Prospective Diagnostic Study

Background: The aim of this study was to examine the correlation of the clinical examination, MRI and arthroscopic findings in cruciate ligaments and meniscal injuries of knee and to evaluate the accuracy of clinical examination and MRI with the gold standard arthroscopy. Methods: A prospective diagnostic double-blind study was conducted on 104 consecutive patients admitted to the outdoor/casualty with trauma to the knee complaining of knee pain/locking/ instability, from August 2012 to June 2014. All the patients were subjected to clinical examination, MRI scanning and diagnostic arthroscopy. Variables like sensitivity, specificity, positive predictive value, negative predictive value and accuracy of clinical examination and MRI against arthroscopy were evaluated. Results: The sensitivity, specificity and accuracy of clinical examination for anterior cruciate ligament tears were 94.7%, 71.4% and 88.5% and for MRI were 94.7%, 78.6% and 90.4%, respectively; for posterior cruciate ligament tears 100%, 100% and 100% for clinical examination and for MRI 80%, 97.9% and 96.2%, respectively. These values for medial meniscus tears were 76.5%, 68.6% and 71.2% for clinical examination and 88.2%, 62.8% and 71.2% respectively for MRI. For lateral meniscus tears, 40%, 94.6% and 78.8% for clinical examination and 46.7%, 89.2% and 76.9% respectively for MRI. Conclusions: A skillfully performed clinical examination establishes a diagnosis on which an arthroscopic procedure can be planned, reserving MRI scans for patients where the clinical examination fails to establish a diagnosis or cannot be performed. Decision to use MRI should be based on the criteria that it would confirm, expand the diagnosis or change diagnosis in such a way that alters the proposed treatment

eNavigate: A Survey On Effective and Efficient User Website Navigation

Web Structure Improvement has attracted much attention now days. The large websites such as E-commerce, universities etc. have lots of pages visited by users daily. The users needed to be navigated effectively and efficiently throughout the website. Each user has its own set of target pages where the stay time is larger than that of other pages. While making website structure improvements the web master must consider the set of target pages of the users. The users’ web log must be maintained at the server side which further has to be divided into session and mini sessions. These mini sessions provides the inputs to extract the target pages of a specific user. The improvement in website must be done under some circumstances. The newly added links must satisfy some criteria such as how many number of links can be added. Previous literature provides some meaningful considerations about static and dynamic websites. The effective website structure improvements along with the set of target pages can be efficiently designed with static and informative websites while it’s difficult to consider the target pages in dynamic one. The structure optimization can be done with minimization or maximization strategies. Here in this survey paper we studied some previously published journals to get better knowledge about the web structure improvements for effective user navigation

Risk Analysis - A Biosecurity Tool to Assess Weed Potential of a Plant

Seeds and planting materials of different plant species are being imported into India. Many of these have the potential to become agricultural or environmental weeds and this risk needs to be assessed before allowing their entry. Weed risk assessment method was judged on its ability to correctly reject weeds and accept non-weeds. Out of 170 plants tested, a total of 40% plants were classified as serious weeds, 30% as common weeds and remaining 30% were non weeds. The system is designed to be operated by plant quarantine officers. The weed risk assessment system with explicit scoring of biological, ecological and geographical attributes is a useful tool for detecting potentially invasive weeds in other areas of the world

Towards a Hybrid Public Key Infrastructure (PKI): A Review

Traditional Certificate-based public key infrastructure (PKI) suffers from the problem of certificate overhead like its storage, verification, revocation etc. To overcome these problems, the idea of certificate less identity-based public key cryptography (ID-PKC) was proposed by Shamir. This is suitable for closed trusted group only. Also, this concept has some inherent problems like key escrow problem, secure key channel problem, identity management overhead etc. Later on, there had been several works which tried to combine both the cryptographic techniques such that the resulting hybrid PKI framework is built upon the best features of both the cryptographic techniques. It had been shown that this approach solves many problems associated with an individual cryptosystem. In this paper, we have reviewed and compared such hybrid schemes which tried to combine both the certificate based PKC and ID-based PKC. Also, the summary of the comparison, based on various features, is presented in a table