Immunological assessment of plant-derived avian flu H5/HA1 variants.

Polypeptide variants of the HA1 antigenic domain of the H5N1 avian influenza virus hemagglutinin (HA) molecule were produced in plants using transient and stable expression systems and fused with His/c-myc tags or with mouse or human Fc antibody fragments. The resulting peptides were purified and used for intramuscular immunization of mice. While the recombinant HA1 variants induced a significant serum humoral immune response in the mice, none of the HA1 preparations induced virus-neutralizing antibodies. Fusion with the Fc fragment improved overall yield of the constructs and allowed purification requiring only a single step, but led to no detectable fusion-related enhancement of immunogenicity or quality of immune response

Single layer and multilayer vacuum-arc coatings based on the nitride tialsiyn: composition, structure, properties

Using high-technological vacuum-arc evaporation in the atmosphere of nitrogen with ion bombardment, single- and multilayer coatings based on TiAlSiYN with high mechanical characteristics were obtained: hardness of the coatings reached 49.5 GPA, resistance to wear, with the value of the critical point LC5 reaching 184.92 N. The mechanisms of structure formation, defining the resulting mechanical characteristics of single- and multi-layer coatings based on TiAlSiYN nitride have been discusse

Features of Physical Development of Schoolchildren in the Conditions of Specialized Training

The article presents a comparative analysis of physical development of 13-year-olds and cadet basic profile of teaching in urban schools in the parameters of somatometry and visiometry characterizing physical development, functional state, adaptation of the heart and body to current training loads. Coming of puberty is marked by intense growth of the body with heterochronous changes in the proportions and dimensions of its muscular skeletal system and the structure of internal organs. During this period, the role of mechanisms for self-regulation of heart activity and, in general, autonomous regulation of the functions of the cardiovascular system increases. At the initial stage in adolescents the manifestation of tachycardia and cardiac type of self-regulation of blood circulation increases. It is accompanied with deterioration in inotropic function of the myocardium against the background of a pronounced effect of sympatotonia and vagotonia on the systolic function of the myocardium

Hemodynamic criteria of the circulatory system in ethnic groups of students with different types of autonomic regulation of the heart rate

Under physiological conditions, the first years of university studies of the students of Arabic and African subgroups with MPAR and PPAR HR were characterized by toughness, low effectiveness of the system of blood circulation, increased peripheral vascular resistance, vascular TSC; Indian and Latino-American subgroups with MPAR HR revealed the weakness and low efficiency of the circulatory system, the optimal GPBC and cardiovascular TSC were revealed in Indian and Latino-American subgroups with MPAR HR, and subgroups with PPAR HR showed high endurance of the circulatory syste

Effect of photoions on the line shapes of the F\"orster resonance and microwave transitions in cold rubidium Rydberg atoms

Experiments on the spectroscopy of the F\"orster resonance Rb(37P)+Rb(37P) -> Rb(37S)+Rb(38S) and microwave transitions nP -> n'S, n'D between Rydberg states of cold Rb atoms in a magneto-optical trap have been performed. Under ordinary conditions, all spectra exhibited a 2-3 MHz line width independently of the interaction time of atoms with each other or with microwave radiation, although the ultimate resonance width should be defined by the inverse interaction time. Analysis of the experimental conditions has shown that the main source of the line broadening was the inhomogeneous electric field of cold photoions appeared at the excitation of initial Rydberg nP states by broadband pulsed laser radiation. Using an additional pulse of the electric field, which rapidly removed the photoions after the laser pulse, lead to a substantial narrowing of the microwave and F\"orster resonances. An analysis of various sources of the line broadening in cold Rydberg atoms has been conducted.Comment: 10 pages, 6 figure

Features of physical development of schoolchildren in the conditions of specialized training

The article presents a comparative analysis of physical development of 13-year-olds and cadet basic profile of teaching in urban schools in the parameters of somatometry and visiometry characterizing physical development, functional state, adaptation of the heart and body to current training loads. Coming of puberty is marked by intense growth of the body with heterochronous changes in the proportions and dimensions of its muscular skeletal system and the structure of internal organs. During this period, the role of mechanisms for self-regulation of heart activity and, in general, autonomous regulation of the functions of the cardiovascular system increase

Research of the Relationship of Happiness with the Virtues and the “Seven Deadly Sins”

Статья поступила в редакцию 05.09.2022 г.В статье приводятся данные о связи счастья с соблюдением моральных норм на примере таких норм-запретов, как алчность, гнев, гордыня, похоть, зависть, уныние, чревоугодие, и таких добродетелей, как мудрость и знание, мужество, гуманизм и любовь, справедливость, умеренность, трансцендентность (духовность). В исследовании приняли участие 114 человек в возрасте от 18 до 60 лет. Для диагностики использовались методики: «Обновленный Оксфордский опросник счастья» (Oxford Happiness Inventory); «Опросник достоинств личности», ОДЛ (Personal Virtues Questionnaire, PVQ); десятибалльные шкалы самооценки алчности, гнева, гордыни, похоти, зависти, уныния, чревоугодия. В результате была выявлена положительная связь счастья со всеми добродетелями, отрицательная связь счастья с алчностью, гневом, завистью, похотью, унынием. При этом счастье положительно коррелирует с гордыней и не связано с чревоугодием.The article presents data on the connection of happiness with the observance of moral standards on the example of such norms prohibitions as anger, greediness, envy,idleness, gluttony, lust and extra pride, and such virtues as wisdom and knowledge, courage, humanism and love, justice, restraint, transcendence (spirituality). The study involved 114 people aged 18 to 60 years. The following methods were used for diagnostics: “Updated Oxford Happiness Inventory”; Personal Virtues Questionnaire (PVQ); 10 point scale the level of self assessment of anger , greediness, envy, idleness, gluttony, lust and extra pride. As a result, a positive relationship of happiness with all virtues was revealed, a negative relationship of happiness with anger, greediness, envy, idleness, lust. At the same time, happiness is positively correlated with extra pride and is not associated with gluttony

A wood-filled composite based on recycled polyethylene terephthalate. Production and properties

The possibility of conducting combined recycling of wood and PETP waste was investigated. The aim was to develop a process for producing composites based on recycled PETP filled with wood flour by the depolymerisation of recycled polymer to polyol, the production of unsaturated polyester, and its subsequent polymerisation with filler into products. The mechanisms of the principal processes occurring in the production of the composite were examined. It was shown that the wood-filled composite produced could be processed by pressing to produce products such as boards, panels, trays and sheets. The properties of the composite (density, elastic modulus, elongation at break and impact strength) were compared with those of a traditional wood-plastic composite. 6 ref

Les Houches 2015: Physics at TeV Colliders Standard Model Working Group Report

This Report summarizes the proceedings of the 2015 Les Houches workshop on Physics at TeV Colliders. Session 1 dealt with (I) new developments relevant for high precision Standard Model calculations, (II) the new PDF4LHC parton distributions, (III) issues in the theoretical description of the production of Standard Model Higgs bosons and how to relate experimental measurements, (IV) a host of phenomenological studies essential for comparing LHC data from Run I with theoretical predictions and projections for future measurements in Run II, and (V) new developments in Monte Carlo event generators.Comment: Proceedings of the Standard Model Working Group of the 2015 Les Houches Workshop, Physics at TeV Colliders, Les Houches 1-19 June 2015. 227 page

Dynamic model of elastoplastic normal collision of spherical particles under nonlocal plasticity

The problem of normal collision of a spherical particle with a half-space is considered with allowance for nonlocal plastic deformation in the case where the strength limit depends on the contact radius, as well as for the strengthening effect in the deformed material. The dimensionless coefficient of normal velocity restitution has been calculated numerically as a function of the initial velocity of the spherical particle. The obtained data coincide well with experimental results available in the literature