Investigation of flame stretch in turbulent lifted jet flame

DNS data of a laboratory-scale turbulent lifted hydrogen jet flame has been analysed to show that this flame has mixed mode combustion not only at the flame base but also in downstream locations. The mixed mode combustion is observed in instantaneous structures as in earlier studies and in averaged structure, in which the predominant mode is found to be premixed combustion with varying equivalence ratio. The nonpremixed combustion in the averaged structure is observed only in a narrow region at the edge of the jet shear layer. The analyses of flame stretch show large probability for negative flame stretch leading to negative surface averaged flame stretch. The displacement speed-curvature correlation is observed to be negative contributing to the negative flame stretch and partial premixing resulting from jet entrainment acts to reduce the negative correlation. The contribution of turbulent straining to the flame stretch is observed to be negative when the scalar gradient aligns with the most extensive principal strain rate. The physics behind the negative flame stretch resulting from turbulent straining is discussed and elucidated through a simple analysis of the flame surface density transport equation.The authors are grateful for the inspiring discussion with Prof. K.N.C. Bray, and financial support from Mitsubishi Heavy Industries (MHI) is gratefully acknowledged. A part of this work is performed under the collaborative research between Cambridge University and JAXA.This is an Accepted Manuscript of an article published by Taylor & Francis in Combustion Science and Technology on 24 February 2014, available online: http://wwww.tandfonline.com/10.1080/00102202.2013.877335

The MAGIC Telescope and the Observation of Gamma Ray Bursts

The MAGIC Telescope, now taking data with an energy threshold well below 100 GeV, will soon be able to take full advantage of the fast slewing capability of its altazimuthal mount. Exploiting the link with the GCN network, the MAGIC Telescope could be one of the first ground-based experiments able to see the prompt emission of Gamma Ray Bursts in the few tens of GeV region.Comment: 4 pages, 1 figure (-> 3 subfigures), class file (cimento.cls) included. To appear in: "Gamma-Ray Bursts in the Afterglow Era: 4rd Workshop", Rome 200

GRB 050713A: High Energy Observations of the GRB Prompt and Afterglow Emission

Swift discovered GRB 050713A and slewed promptly to begin observing with its narrow field instruments 72.6 seconds after the burst onset, while the prompt gamma-ray emission was still detectable in the BAT. Simultaneous emission from two flares is detected in the BAT and XRT. This burst marks just the second time that the BAT and XRT have simultaneously detected emission from a burst and the first time that both instruments have produced a well sampled, simultaneous dataset covering multiple X-ray flares. The temporal rise and decay parameters of the flares are consistent with the internal shock mechanism. In addition to the Swift coverage of GRB 050713A, we report on the Konus-Wind (K-W) detection of the prompt emission in the energy range 18-1150 keV, an upper limiting GeV measurement of the prompt emission made by the MAGIC imaging atmospheric Cherenkov telescope and XMM-Newton observations of the afterglow. Simultaneous observation between Swift XRT and XMM-Newton produce consistent results, showing a break in the lightcurve at T+~15ks. Together, these four observatories provide unusually broad spectral coverage of the prompt emission and detailed X-ray follow-up of the afterglow for two weeks after the burst trigger. Simultaneous spectral fits of K-W with BAT and BAT with XRT data indicate that an absorbed broken powerlaw is often a better fit to GRB flares than a simple absorbed powerlaw. These spectral results together with the rapid temporal rise and decay of the flares suggest that flares are produced in internal shocks due to late time central engine activity.Comment: 22 pages, 6 tables, 10 figures; Submitted to the Astrophysical Journa

Virulence Potential of Staphylococcus aureus Strains Isolated From Diabetic Foot Ulcers: A new paradigm

OBJECTIVE—The purpose of this study was to assess the virulence potential of Staphylococcus aureus strains isolated from diabetic foot ulcers and to discriminate noninfected from infected ulcers

Clinical and genetic characteristics of 10 Japanese patients with PROM1-associated retinal disorder: A report of the phenotype spectrum and a literature review in the Japanese population

Variants in the PROM1 gene are associated with cone (-rod) dystrophy, macular dystrophy, and other phenotypes. We describe the clinical and genetic characteristics of 10 patients from eight Japanese families with PROM1-associated retinal disorder (PROM1-RD) in a nationwide cohort. A literature review of PROM1-RD in the Japanese population was also performed. The median age at onset/examination of 10 patients was 31.0 (range, 10-45)/44.5 (22-73) years. All 10 patients showed atrophic macular changes. Seven patients (70.0%) had spared fovea to various degrees, approximately half of whom had maintained visual acuity. Generalized cone (-rod) dysfunction was demonstrated in all nine subjects with available electrophysiological data. Three PROM1 variants were identified in this study: one recurrent disease-causing variant (p.Arg373Cys), one novel putative disease-causing variant (p.Cys112Arg), and one novel variant of uncertain significance (VUS; p.Gly53Asp). Characteristic features of macular atrophy with generalized cone-dominated retinal dysfunction were shared among all 10 subjects with PROM1-RD, and the presence of foveal sparing was crucial in maintaining visual acuity. Together with the three previously reported variants [p.R373C, c.1551+1G>A (pathogenic), p.Asn580His (likely benign)] in the literature of Japanese patients, one prevalent missense variant (p.Arg373Cys, 6/9 families, 66.7%) detected in multiple studies was determined in the Japanese population, which was also frequently detected in the European population