SUMSS: A Wide-Field Radio Imaging Survey of the Southern Sky. I. Science goals, survey design and instrumentation

The Molonglo Observatory Synthesis Telescope, operating at 843 MHz with a 5 square degree field of view, is carrying out a radio imaging survey of the sky south of declination -30 deg. This survey (the Sydney University Molonglo Sky Survey, or SUMSS) produces images with a resolution of 43" x 43" cosec(Dec.) and an rms noise level of about 1 mJy/beam. SUMSS is therefore similar in sensitivity and resolution to the northern NRAO VLA Sky Survey (NVSS; Condon et al. 1998). The survey is progressing at a rate of about 1000 square degrees per year, yielding individual and statistical data for many thousands of weak radio sources. This paper describes the main characteristics of the survey, and presents sample images from the first year of observation.Comment: 27 pages, 12 figures (figures 2, 8, 10 in jpg format); AJ, in pres

Black-holes, topological strings and large N phase transitions

The counting of microstates of BPS black-holes on local Calabi-Yau of the form ${\mathcal O}(p-2)\oplus{\mathcal O}(-p) \longrightarrow S^2$ is explored by computing the partition function of q-deformed Yang-Mills theory on $S^2$. We obtain, at finite $N$, the instanton expansion of the gauge theory. It can be written exactly as the partition function for U(N) Chern-Simons gauge theory on a Lens space, summed over all non-trivial vacua, plus a tower of non-perturbative instanton contributions. In the large $N$ limit we find a peculiar phase structure in the model. At weak string coupling the theory reduces to the trivial sector and the topological string partition function on the resolved conifold is reproduced in this regime. At a certain critical point, instantons are enhanced and the theory undergoes a phase transition into a strong coupling regime. The transition from the strong coupling phase to the weak coupling phase is of third order.Comment: 16 pages, 3 figures; Invited talk given at QG05, Cala Gonone (Italy), September 200

The Distribution of H2O Maser Emission in the Nucleus of NGC 4945

We present the first interferometer map of the water maser emission in the active nucleus of NGC 4945. Although the declination of the galaxy is about -49 degrees, we were able to make the observations with the southernmost antennas of the Very Long Baseline Array. Strong maser emission is present in three velocity ranges, one near the systemic velocity and two shifted roughly symmetrically by +/-(100-150) km/s. This is the first detection of highly blue-shifted water emission in NGC 4945. We determined the position of the maser to be RA(B1950)= 13 02 32.28 +/- 0.02 ; Dec(B1950)= -49 12 01.9 +/- 0.1. The uncertainties in earlier estimates are at least several arcseconds. The maser lies within 2'' (36 pc at a distance of 3.7 Mpc) of the peaks in 1.4 GHz continuum and 1.6 micron emission from the nucleus. The mappable maser emission is distributed roughly linearly over about 40 milliarcseconds (0.7 pc) at a position angle of about 45 degrees, which is close to the 43 +/- 2 degree position angle of the galactic disk. The red and blue-shifted emission symmetrically stradle the systemic emission on the sky, which suggests material in edge-on circular motion around a central object. The position-velocity structure indicates a binding mass of about one million Suns, within a volume of radius about 0.3 pc. This implies that the central engine radiates on the order of 10% of its Eddington luminosity.Comment: 18 pages, including 5 Postscript figures. Accepted for publication in ApJ Letter

Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease

Study identifying an Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease presented at the annual congress of the british toxicology societ

Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP3 and PIP2 in rabbit coronary artery myocytes

We investigate activation mechanisms of native TRPC1/C5/C6 channels (termed TRPC1 channels) by stimulation of endothelin-1 (ET-1) receptor subtypes in freshly dispersed rabbit coronary artery myocytes using single channel recording and immunoprecipitation techniques. ET-1 evoked non-selective cation channel currents with a unitary conductance of 2.6 pS which were not inhibited by either ET(A) or ET(B) receptor antagonists, respectively BQ-123 and BQ788, when administered separately. However, in the presence of both antagonists, ET-1-evoked channel activity was abolished indicating that both ET(A) and ET(B) receptor stimulation activate this conductance. Stimulation of both ET(A) and ET(B) receptors evoked channel activity which was inhibited by the protein kinase C (PKC) inhibitor chelerythrine and by anti-TRPC1 antibodies indicating that activation of both receptor subtypes causes TRPC1 channel activation by a PKC-dependent mechanism. ET(A) receptor-mediated TRPC1 channel activity was selectively inhibited by phosphoinositol-3-kinase (PI-3-kinase) inhibitors wortmannin (50 nm) and PI-828 and by antibodies raised against phosphoinositol-3,4,5-trisphosphate (PIP(3)), the product of PI-3-kinase-mediated phosphorylation of phosphatidylinositol 4,5-bisphosphate (PIP(2)). Moreover, exogenous application of diC8-PIP(3) stimulated PKC-dependent TRPC1 channel activity. These results indicate that stimulation of ET(A) receptors evokes PKC-dependent TRPC1 channel activity through activation of PI-3-kinase and generation of PIP(3). In contrast, ET(B) receptor-mediated TRPC1 channel activity was inhibited by the PI-phospholipase C (PI-PLC) inhibitor U73122. 1-Oleoyl-2-acetyl-sn-glycerol (OAG), an analogue of diacylglycerol (DAG), which is a product of PI-PLC, also activated PKC-dependent TRPC1 channel activity. OAG-induced TRPC1 channel activity was inhibited by anti-phosphoinositol-4,5-bisphosphate (PIP(2)) antibodies and high concentrations of wortmannin (20 μm) which depleted tissue PIP(2) levels. In addition exogenous application of diC8-PIP(2) activated PKC-dependent TRPC1 channel activity. These data indicate that stimulation of ET(B) receptors evokes PKC-dependent TRPC1 activity through PI-PLC-mediated generation of DAG and requires a permissive role of PIP(2). In conclusion, we provide the first evidence that stimulation of ET(A) and ET(B) receptors activate native PKC-dependent TRPC1 channels through two distinct phospholipids pathways involving a novel action of PIP(3), in addition to PIP(2), in rabbit coronary artery myocytes

Synchronizing Sequencing Software to a Live Drummer

Copyright 2013 Massachusetts Institute of Technology. MIT allows authors to archive published versions of their articles after an embargo period. The article is available at

D-Instantons and asymptotic geometries

The large N limit of D3-branes is expected to correspond to a superconformal field theory living on the boundary of the anti-de Sitter space appearing in the near-horizon geometry. Dualizing the D3-brane to a D-instanton, we show that this limit is equivalent to a type IIB S-duality. In both cases one effectively reaches the near-horizon geometry. This provides an alternative approach to an earlier derivation of the same result that makes use of the properties of a gravitational wave instead of the D-instanton.Comment: 17 pages, LaTeX, 1 figure, minor corrections and refs adde

1981 Hay Day report : Forage Systems Research Center, Linneus, Mo.

Includes reprints of articles from "UMC science and technology guide", "Making and storing quality hay" and "Large round balers.