501 research outputs found

    Anatomical Changes in the Skin of Rattus Norvegicus After Artificial UV Exposure

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    Acute and subacute artificial UV exposure to albino rats exhibit morphological and histo-anatomical changes in the skin of albino rat. The anatomical changes include hyperplasia, hyperkeratosis, hypergranulosis and acanthosis beside numerical changes in keratinocytes, Langerhans, melanocytes and fibroblast seen after acute and subacute artificial UVB exposure

    Anatomical Changes in the Skin of Rattus norvegicus after Artificial UV Exposure

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    Acute and subacute artificial UV exposure to albino rats exhibit morphological and histo-anatomical changes in the skin of albino rat. The anatomical changes include hyperplasia, hyperkeratosis, hypergranulosis and acanthosis beside numerical changes in keratinocytes, Langerhans, melanocytes and fibroblast seen after acute and subacute artificial UVB exposure

    Changes in loneliness prevalence and its associated factors among Bangladeshi older adults during the COVID-19 pandemic

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    Aims Worldwide, loneliness is one of the most common psychological phenomena among older adults, adversely affecting their physical and mental health conditions during the COVID-19 pandemic. This study aims to assess changes in the prevalence of loneliness in the two timeframes (first and second waves of COVID-19 in Bangladesh) and identify its correlates in pooled data. Methods This repeated cross-sectional study was conducted on two successive occasions (October 2020 and September 2021), overlapping with the first and second waves of the COVID-19 pandemic in Bangladesh. The survey was conducted remotely through telephone interviews among 2077 (1032 in the 2020-survey and 1045 in the 2021-survey) older Bangladeshi adults aged 60 years and above. Loneliness was measured using the 3-item UCLA Loneliness scale. The binary logistic regression model was used to identify the factors associated with loneliness in pooled data. Results We found a decline in the loneliness prevalence among the participants in two survey rounds (51.5% in 2021 versus 45.7% in 2020; P = 0.008), corresponding to 33% lower odds in the 2021-survey (AOR 0.67, 95% CI 0.54-0.84). Still, nearly half of the participants were found to be lonely in the latest survey. We also found that, compared to their respective counterparts, the odds of loneliness were significantly higher among the participants without a partner (AOR 1.58, 95% CI 1.20-2.08), with a monthly family income less than 5000 BDT (AOR 2.34, 95% CI 1.58-3.47), who lived alone (AOR 2.17, 95% CI 1.34-3.51), with poor memory or concentration (AOR 1.58, 95% CI 1.23-2.03), and suffering from non-communicable chronic conditions (AOR 1.55, 95% CI 1.23-1.95). Various COVID-19-related characteristics, such as concern about COVID-19 (AOR 1.28, 95% CI 0.94-1.73), overwhelm by COVID-19 (AOR 1.53, 95% CI 1.14-2.06), difficulty earning (AOR 2.00, 95% CI 1.54-2.59), and receiving routine medical care during COVID-19 (AOR 2.08, 95% CI 1.61-2.68), and perception that the participants required additional care during the pandemic (AOR 2.93, 95% CI 2.27-3.79) were also associated with significantly higher odds of loneliness. However, the odds of loneliness were significantly lower among the participants with formal schooling (AOR 0.71, 95% CI 0.57-0.89) and with a family of more than four members (AOR 0.76, 95% CI 0.60-0.96). Conclusions The current study found a decreased prevalence of loneliness among Bangladeshi older adults during the ongoing pandemic. However, the prevalence is still very high. The findings suggest the need for mental health interventions that may include improving social interactions increasing opportunities for meaningful social connections with family and community members and providing psychosocial support to the vulnerable population including older adults during the pandemic. It also suggests that policymakers and public health practitioners should emphasise providing mental health services at the peripheral level where the majority of older adults reside

    Prospective study on quality of newborn care

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    Background: Quality of services provided by health care provider, the closest health functionary to the community has impact on neonatal mortality. Aims: Study on quality of newborn care in rural areas.  Settings and Design: This is a prospective study in the field practice areas of J.N. Medical College and areas under primary health centre of public health care system in Wardha district.  Methods and Material: Modified quality check list on the basis of PHC MAP module guidelines for assessing the quality of service-module 6-user’s guide was prepared. Face to face interview with 205 (group-A/104 nos + group-B/101 nos) mother of newborn was method to collected information in three postnatal visits.  Statistical analysis: Quality (verbal response) of each service was quantified as acceptable, average and worst.  Quality of both the groups was compared by calculating P-value after utilizing Z-test.  Results: Over all acceptable quality of medical history was 30.03%, physical examination was 21.73%, preventive service was 91.17% and counseling was 24.83%. Significant difference between two groups were found on history taking for (cry, breathing and body movement of baby), recording weight and counseling regarding exclusive breast feeding for first 6 month of life. Worst quality in this study were observed in history for anything applying to eyes, umbilical cord stump and complication of baby for which appropriate management was taken. Except for weight recording and examination of head and fontanels all other variables under physical examination were not acceptable. Counseling regarding high risk condition of baby was only 13.66%. Conclusion: Existing newborn services except immunization is inadequate and needs to be strengthened especially physical examination and counseling services

    Mixed-metal Cluster Synthesis: [Re(CO)\u3csub\u3e3\u3c/sub\u3e(μ-S\u3csub\u3e2\u3c/sub\u3eNC\u3csub\u3e7\u3c/sub\u3eH\u3csub\u3e4\u3c/sub\u3e)]\u3csub\u3e2\u3c/sub\u3e as a Precursor for tri- and tetranuclear 2-mercaptobenzothiolato Capped Clusters

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    The readily prepared [Re2(CO)6(μ-S2NC7H4)2] (1) reacts with Group 8 trimetallic carbonyl clusters to yield new mixed-metal tri- and tetranuclear clusters. With [Os3(CO)10(NCMe)2] at 80 °C the tetranuclear mixed-metal cluster [Os3Re(CO)13(μ3-C7H4NS2)] (2) is the only isolated product. With Ru3(CO)12 products are dependent upon the reaction temperature. At 80 °C, a mixture of tetranuclear mixed-metal [Ru3Re(CO)13(μ3-C7H4NS2)] (5) and the triruthenium complex [Ru3(CO)9(μ-H)(μ3-C7H4NS2)] (4) results, while at 110 °C a second tetranuclear mixed-metal cluster, [Re2Ru2(CO)12(μ4-S)(μ-C7H4NS)(μ-C7H4NS2)] (3), resulting from carbon–sulfur bond scission, is the major product. Reaction of 1 With Fe3(CO)12 at 80 °C furnishes the trinuclear mixed-metal cluster [Fe2Re(CO)8(μ-CO)2(μ3-C7H4NS2)] (6). The reactivity of 6 has been probed with the aim of identifying any metal-based selectivity for carbonyl substitution. Addition of PPh3 in presence of Me3NO at 25 °C gives both the mono- and bis(phosphine)-substituted derivatives [Os3Re(CO)12(PPh3)(μ3-C7H4NS2)] (7) and [Os3Re(CO)11(PPh3)2(μ3-C7H4NS2)] (8). In 7 the PPh3 ligand occupies an axial site on wingtip osmium, while in 8 one PPh3 ligand is equatorially coordinated to wingtip osmium and the other is bonded to a hinge osmium. New complexes have been characterized by a combination of spectroscopic data and single crystal X-ray diffraction studies

    Conservation Status of the Indian Peafowl Pavo cristatus (Aves: Galliformes: Phasianidae) in Bangalore University Campus, Bengaluru, Karnataka, India

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    The Indian Peafowl, Pavo cristatus was abundant in Bangalore University Campus (BUC) during 1970-80. However, the peafowl population declined alarmingly in the BUC region after 1990. The present paper deals with the abundance, sex ratio of peafowls and their conservation methods in the Biodiversity Park (Bio-Park) of BUC, which had been established in 2006. A total of 117 peafowls was recorded in the BUC region in which the females outnumbered the males. The increased abundance of the peafowl population in the campus could be mainly due to the availability of suitable roosting, foraging and nesting sites. The peafowls have used 18 species of plants and trees for perching and roosting in BUC. The peafowl population increased in the BUC region due to habitat rejuvenation and protection, availability of food sources and breeding/nesting sites. The results of the present investigation constitute the baseline data for the further understanding of the ecological community of national bird in the protected habitats as hotspots for biodiversity of urban ecosystem. Conservation of microhabitats through the proper restoration of ponds, streams and water check-dams including vegetation in the BUC is responsible for the existence of peafowl population

    Conservation Status of the Indian Peafowl Pavo cristatus (Aves: Galliformes: Phasianidae) in Bangalore University Campus, Bengaluru, Karnataka, India

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    The Indian Peafowl, Pavo cristatus was abundant in Bangalore University Campus (BUC) during 1970-80. However, the peafowl population declined alarmingly in the BUC region after 1990. The present paper deals with the abundance, sex ratio of peafowls and their conservation methods in the Biodiversity Park (Bio-Park) of BUC, which had been established in 2006. A total of 117 peafowls was recorded in the BUC region in which the females outnumbered the males. The increased abundance of the peafowl population in the campus could be mainly due to the availability of suitable roosting, foraging and nesting sites. The peafowls have used 18 species of plants and trees for perching and roosting in BUC. The peafowl population increased in the BUC region due to habitat rejuvenation and protection, availability of food sources and breeding/nesting sites. The results of the present investigation constitute the baseline data for the further understanding of the ecological community of national bird in the protected habitats as hotspots for biodiversity of urban ecosystem. Conservation of microhabitats through the proper restoration of ponds, streams and water check-dams including vegetation in the BUC is responsible for the existence of peafowl population

    Soxhlet extraction cycle-dependent diversity in phenolic profile and antioxidant potency of red cabbage

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    Introduction: The Brassicaceae vegetables are a rich source of secondary metabolites that exhibit several health benefits and protection against numerous degenerative diseases. Objectives: The current study was performed to investigate the effect of Soxhlet extraction cycles on the phenolic profile of red cabbage (Brassica oleracea var. capitata F. rubra) and its biological activities. Materials and Methods: The red cabbage sample was harvested from the research fields of Ayub Agricultural Research Institute Faisalabad, Pakistan. The ethanol extracts were prepared using 1-, 2-, 4-, and 8-cycles Soxhlet extraction technique. The antioxidant potential of red cabbage extracts was estimated by evaluation of total phenolic contents (TPC), total flavonoid contents (TFC), DPPH radical scavenging capacity and reducing power. The identification and quantification of polyphenols were carried out by RP-HPLC. The antibacterial activity of red cabbage extracts was determined against Escherichia coli and Staphylococcus aureus and the antiproliferative activity was carried out by MTT mitochondrial viability assay against the human A549 cancer cell line. Results: Gallic acid, p-hydroxyl benzoic acid, chlorogenic acid, and p-coumaric acid were the major phenolic acids, whereas catechin and quercetin were the major flavonoids detected in the red cabbage extracts. The extraction cycles were found to have significant (p ≤ 0.05) effects on the phenolic profile of the red cabbage extracts. TPC of extracts ranged from 5.22-11.72 mg/g dry matter, measured as gallic acid equivalent, while the TFC ranged from 1.64-5.19 mg/g dry matter; measured as catechin equivalent. The 4-cycles extract of red cabbage exhibited the maximum TPC, TFC, and DPPH free-radical scavenging and reducing activity. Conclusion: The study concluded that the Soxhlet extraction cycles could exert a considerable effect on the yield and polyphenol composition of red cabbage extracts as well as their antioxidant potential. Antibacterial and antiproliferative activities were observed by all the extracts of red cabbage

    ‘We need to share our stories’: the lives of Pakistanis with intellectual disability and their guardians

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    © 2020 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd Introduction: The experiences of Pakistanis with intellectual disabilities (IDs) and their family members have been underexplored empirically. Method: The present study sought to address this gap by understanding the lives of five Special Olympics Pakistan athletes and their guardians through PhotoVoice. Findings: Through thematic analysis, we present the primary theme concerning Pakistan\u27s cultural context that provides an empirical exploration of cultural beliefs about intellectual disability, cultural expectations and support received by people with intellectual disabilities and their guardians. Discussion: We discuss implications for research and practice
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