187 research outputs found
Experimental study of optimal measurements for quantum state tomography
Quantum tomography is a critically important tool to evaluate quantum
hardware, making it essential to develop optimized measurement strategies that
are both accurate and efficient. We compare a variety of strategies using
nearly pure test states. Those that are informationally complete for all states
are found to be accurate and reliable even in the presence of errors in the
measurements themselves, while those designed to be complete only for pure
states are far more efficient but highly sensitive to such errors. Our results
highlight the unavoidable tradeoffs inherent to quantum tomography.Comment: 5 pages, 3 figure
Quantum State Tomography Using Successive Measurements
We describe a quantum state tomography scheme which is applicable to a system
described in a Hilbert space of arbitrary finite dimensionality and is
constructed from sequences of two measurements. The scheme consists of
measuring the various pairs of projectors onto two bases --which have no
mutually orthogonal vectors--, the two members of each pair being measured in
succession. We show that this scheme implies measuring the joint
quasi-probability of any pair of non-degenerate observables having the two
bases as their respective eigenbases. The model Hamiltonian underlying the
scheme makes use of two meters initially prepared in an arbitrary given quantum
state, following the ideas that were introduced by von Neumann in his theory of
measurement.Comment: 12 Page
Fisher-Symmetric Informationally Complete Measurements for Pure States
© 2016 American Physical Society. We introduce a new kind of quantum measurement that is defined to be symmetric in the sense of uniform Fisher information across a set of parameters that uniquely represent pure quantum states in the neighborhood of a fiducial pure state. The measurement is locally informationally complete - i.e., it uniquely determines these parameters, as opposed to distinguishing two arbitrary quantum states - and it is maximal in the sense of a multiparameter quantum Cramér-Rao bound. For a d-dimensional quantum system, requiring only local informational completeness allows us to reduce the number of outcomes of the measurement from a minimum close to but below 4d-3, for the usual notion of global pure-state informational completeness, to 2d-1
Deregulated calcium signaling in blood cancer: Underlying mechanisms and therapeutic potential
Intracellular calcium signaling regulates diverse physiological and pathological processes. In solid tumors, changes to calcium channels and effectors via mutations or changes in expression affect all cancer hallmarks. Such changes often disrupt transport of calcium ions (Ca) in the endoplasmic reticulum (ER) or mitochondria, impacting apoptosis. Evidence rapidly accumulates that this is similar in blood cancer. Principles of intracellular Ca signaling are outlined in the introduction. We describe different Ca-toolkit components and summarize the unique relationship between extracellular Ca in the endosteal niche and hematopoietic stem cells. The foundational data on Ca homeostasis in red blood cells is discussed, with the demonstration of changes in red blood cell disorders. This leads to the role of Ca in neoplastic erythropoiesis. Then we expand onto the neoplastic impact of deregulated plasma membrane Ca channels, ER Ca channels, Ca pumps and exchangers, as well as Ca sensor and effector proteins across all types of hematologic neoplasms. This includes an overview of genetic variants in the Ca-toolkit encoding genes in lymphoid and myeloid cancers as recorded in publically available cancer databases. The data we compiled demonstrate that multiple Ca homeostatic mechanisms and Ca responsive pathways are altered in hematologic cancers. Some of these alterations may have genetic basis but this requires further investigation. Most changes in the Ca-toolkit do not appear to define/associate with specific disease entities but may influence disease grade, prognosis, treatment response, and certain complications. Further elucidation of the underlying mechanisms may lead to novel treatments, with the aim to tailor drugs to different patterns of deregulation. To our knowledge this is the first review of its type in the published literature. We hope that the evidence we compiled increases awareness of the calcium signaling deregulation in hematologic neoplasms and triggers more clinical studies to help advance this field
Diagnostic method of typological heterogeneity of arterial blood pressure reactions in children by automatic manometry
Method and algorithm have created by authors for detection of hypotonic, hypertonic and dystonic reactions of blood pressure (BP) in children by automatic manometry during one visit. The study of children in some kindergarten have demonstrated the prevalence of the BP reaction types among children with normal, high BP and arterial hypertension. This easy method may be to use for widespread routine physical examination of all children.Авторами разработан метод и алгоритм для выявления гипотонических, гипертонических и дистонических реакций артериальное давления у детей по данным автоматической манометрии во время одного визита. Обследование детей в одном из детских садов показало распространенность этих типов реакций у лиц с нормальным, высоким нормальным и артериальной гипертонией. Данный метод может быть широко использован при обычном физикальном обследовании всех детей
Under-reporting bicycle accidents to police in the COST TU1101 international survey: Cross-country comparisons and associated factors
Police crash reports are often the main source for official data in many countries. However, with the exception of fatal crashes, crashes are often underreported in a biased manner. Consequently, the countermeasures adopted according to them may be inefficient. In the case of bicycle crashes, this bias is most acute and it probably varies across countries, with some of them being more prone to reporting accidents to police than others. Assessing if this bias occurs and the size of it can be of great importance for evaluating the risks associated with bicycling. This study utilized data collected in the COST TU1101 action “Towards safer bicycling through optimization of bicycle helmets and usage”. The data came from an online survey that included questions related to bicyclists' attitudes, behaviour, cycling habits, accidents, and patterns of use of helmets. The survey was filled by 8655 bicyclists from 30 different countries. After applying various exclusion factors, 7015 questionnaires filled by adult cyclists from 17 countries, each with at least 100 valid responses, remained in our sample. The results showed that across all countries, an average of only 10% of all crashes were reported to the police, with a wide range among countries: from a minimum of 0.0% (Israel) and 2.6% (Croatia) to a maximum of a 35.0% (Germany). Some factors associated with the reporting levels were type of crash, type of vehicle involved, and injury severity. No relation was found between the likelihood of reporting and the cyclist's gender, age, educational level, marital status, being a parent, use of helmet, and type of bicycle. The significant under-reporting – including injury crashes that do not lead to hospitalization – justifies the use of self-report survey data for assessment of bicycling crash patterns as they relate to (1) crash risk issues such as location, infrastructure, cyclists' characteristics, and use of helmet and (2) strategic approaches to bicycle crash prevention and injury reduction.Fil: Shinar, D.. Ben Gurion University of the Negev; IsraelFil: Valero Mora, Pedro. Universidad de Valencia; EspañaFil: van Strijp Houtenbos, M.. Institute For Road Safety Research; Países BajosFil: Haworth, N.. Queensland University of Technology; AustraliaFil: Schramm, A.. Queensland University of Technology; AustraliaFil: de Bruyne, G.. Universiteit Antwerp; BélgicaFil: Cavallo, V.. No especifíca;Fil: Chliaoutakis, J.. No especifíca;Fil: Pereira Dias, Joao. Instituto Superior Tecnico; PortugalFil: Ferraro, Ottavia Eleonora. Universita Degli Studi Di Pavia; ItaliaFil: Fyhri, Aslak. No especifíca;Fil: Sajatovic, Anika Hursa. No especifíca;Fil: Kuklane, Kalev. Lund University; SueciaFil: Ledesma, Ruben Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Psicología Básica, Aplicada y Tecnología. Universidad Nacional de Mar del Plata. Facultad de Psicología. Instituto de Psicología Básica, Aplicada y Tecnología.; ArgentinaFil: Calvé Mascarell, Oscar. Ben Gurion University of the Negev; IsraelFil: Morandi, A.. Universita Degli Studi Di Pavia; ItaliaFil: Muser, Markus. No especifíca;Fil: Otte, Diettmar. No especifíca;Fil: Papadakaki, M.. No especifíca;Fil: Sanmartín, J.. Universidad de Valencia; EspañaFil: Dulf, D.. No especifíca;Fil: Saplioglu, M.. No especifíca;Fil: Tzamalouka, Georgia. No especifíca
Local Hidden Variables Underpinning of Entanglement and Teleportation
Entangled states whose Wigner functions are non-negative may be viewed as
being accounted for by local hidden variables (LHV). Recently, there were
studies of Bell's inequality violation (BIQV) for such states in conjunction
with the well known theorem of Bell that precludes BIQV for theories that have
LHV underpinning. We extend these studies to teleportation which is also based
on entanglement. We investigate if, to what extent, and under what conditions
may teleportation be accounted for via LHV theory. Our study allows us to
expose the role of various quantum requirements. These are, e.g., the
uncertainty relation among non-commuting operators, and the no-cloning theorem
which forces the complete elimination of the teleported state at its initial
port.Comment: 24 pages, 1 figure, accepted Found. Phy
Typological classification of health groups of schoolboys with comorbidity and behavioural risk factors
The purpose of study is estimation of a state of health by typological classification Complex examination of 142 girls and 116 boys in the age of 14-17 years has shown, that 2,1 % of girls and 11,2% of boys have la type of the status of health without risk factors. Premorbid types (lla, lib, lie) were in 20,4% and 25,9% accordingly. Among schoolboys persons with monomorbid (40,9% and 43,0 %) and bimorbid (23,9% and 12,1%) types of the status of health (Ilia and lllb) prevailed. Comorbidity is revealed in 68,3% of girls and 52,3% of boys. A prevailing pathology were dysplasia of connective tissue.Цель исследования оценить состояние здоровья подростков в соответствии с типологической классификацией. Комплексное обследование 142 девонек и 116 мальчиков в возрасте 14-17 лет показало, что 2,1 % девочек и 11,2% мальчиков относятся к la типу статуса здоровья без факторов риска. Преморбидные типы (На, НЬ, Не) были в 20,4% и 25,9% соответственно. Среди школьников преобладали лица с мономорбидным (40,9% и 43,0%) и биморбидным (23,9% и 12,1 %) типами статуса здоровья (Ша и lllb). Коморбидная патология выявлена в 68,3% девочек и 52,3% мальчиков. Преобладающей патологией была дисплазия соединительной ткани
Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish
Multiple signaling pathways control the specification of endothelial cells (ECs) to become arteries or veins during vertebrate embryogenesis. Current models propose that a cascade of Hedgehog (Hh), vascular endothelial growth factor (VEGF), and Notch signaling acts instructively on ECs to control the choice between arterial or venous fate. Differences in the phenotypes induced by Hh, VEGF, or Notch inhibition suggest that not all of the effects of Hh on arteriovenous specification are mediated by VEGF. We establish that full derepression of the Hh pathway in ptc1;ptc2 mutants converts the posterior cardinal vein into a second arterial vessel that manifests intact arterial gene expression, intersegmental vessel sprouting, and HSC gene expression. Importantly, although VEGF was thought to be absolutely essential for arterial fates, we find that normal and ectopic arterial differentiation can occur without VEGF signaling in ptc1;ptc2 mutants. Furthermore, Hh is able to bypass VEGF to induce arterial differentiation in ECs via the calcitonin receptor-like receptor, thus revealing a surprising complexity in the interplay between Hh and VEGF signaling during arteriovenous specification. Finally, our experiments establish a dual function of Hh during induction of runx1+ HSCs
- …