3,939 research outputs found
Evaluation and demonstration of the use of cryogenic propellants /oxygen/hydrogen/ for reaction control systems. Volume 2 - Experimental evaluations and demonstration Final report
Evaluation and demonstration of cryogenic propellant /oxygen-hydrogen/ use for spacecraft reaction control system
Suggestions from the Practicing Bar: Things Practitioners Wish the Court of Appeals Would Do Differently
Suggestions from the Practicing Bar: Things Practitioners Wish the Court of Appeals Would Do Differently
Temporal Variability of Urinary Phthalate Metabolite Levels in Men of Reproductive Age
Phthalates are a family of multifunctional chemicals widely used in personal care and other consumer products. The ubiquitous use of phthalates results in human exposure through multiple sources and routes, including dietary ingestion, dermal absorption, inhalation, and parenteral exposure from medical devices containing phthalates. We explored the temporal variability over 3 months in urinary phthalate metabolite levels among 11 men who collected up to nine urine samples each during this time period. Eight phthalate metabolites were measured by solid-phase extraction–high-performance liquid chromatography–tandem mass spectrometry. Statistical analyses were performed to determine the between- and within-subject variance apportionment, and the sensitivity and specificity of a single urine sample to classify a subject’s 3-month average exposure. Five of the eight phthalates were frequently detected. Monoethyl phthalate (MEP) was detected in 100% of samples; monobutyl phthalate, monobenzyl phthalate, mono-2-ethylhexyl phthalate (MEHP), and monomethyl phthalate were detected in > 90% of samples. Although we found both substantial day-to-day and month-to-month variability in each individual’s urinary phthalate metabolite levels, a single urine sample was moderately predictive of each subject’s exposure over 3 months. The sensitivities ranged from 0.56 to 0.74. Both the degree of between- and within-subject variance and the predictive ability of a single urine sample differed among phthalate metabolites. In particular, a single urine sample was most predictive for MEP and least predictive for MEHP. These results suggest that the most efficient exposure assessment strategy for a particular study may depend on the phthalates of interest
Temporal solitons in optical microresonators
Dissipative solitons can emerge in a wide variety of dissipative nonlinear
systems throughout the fields of optics, medicine or biology. Dissipative
solitons can also exist in Kerr-nonlinear optical resonators and rely on the
double balance between parametric gain and resonator loss on the one hand and
nonlinearity and diffraction or dispersion on the other hand. Mathematically
these solitons are solution to the Lugiato-Lefever equation and exist on top of
a continuous wave (cw) background. Here we report the observation of temporal
dissipative solitons in a high-Q optical microresonator. The solitons are
spontaneously generated when the pump laser is tuned through the effective zero
detuning point of a high-Q resonance, leading to an effective red-detuned
pumping. Red-detuned pumping marks a fundamentally new operating regime in
nonlinear microresonators. While usually unstablethis regime acquires unique
stability in the presence of solitons without any active feedback on the
system. The number of solitons in the resonator can be controlled via the pump
laser detuning and transitions to and between soliton states are associated
with discontinuous steps in the resonator transmission. Beyond enabling to
study soliton physics such as soliton crystals our observations open the route
towards compact, high repetition-rate femto-second sources, where the operating
wavelength is not bound to the availability of broadband laser gain media. The
single soliton states correspond in the frequency domain to low-noise optical
frequency combs with smooth spectral envelopes, critical to applications in
broadband spectroscopy, telecommunications, astronomy and low phase-noise
microwave generation.Comment: Includes Supplementary Informatio
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