36 research outputs found
Electron-impact rotational and hyperfine excitation of HCN, HNC, DCN and DNC
Rotational excitation of isotopologues of HCN and HNC by thermal
electron-impact is studied using the molecular {\bf R}-matrix method combined
with the adiabatic-nuclei-rotation (ANR) approximation. Rate coefficients are
obtained for electron temperatures in the range 56000 K and for transitions
among all levels up to J=8. Hyperfine rates are also derived using the
infinite-order-sudden (IOS) scaling method. It is shown that the dominant
rotational transitions are dipole allowed, that is those for which . The hyperfine propensity rule is found to be stronger
than in the case of HeHCN collisions. For dipole allowed transitions,
electron-impact rates are shown to exceed those for excitation of HCN by He
atoms by 6 orders of magnitude. As a result, the present rates should be
included in any detailed population model of isotopologues of HCN and HNC in
sources where the electron fraction is larger than 10, for example in
interstellar shocks and comets.Comment: 12 pages, 4 figures, accepted in MNRAS (2007 september 3
Future studies on electron scattering; A renaissance
2014 is the centenary of the first announcement of the Franck-Hertz experiment [1], now regarded as one of the pivotal experiments of modern physics. The Franck-Hertz experiment is widely regarded as an experiment that provided validation of the Bohr theory of atomic structure, itself only published in 2013, however it should also be viewed as the first quantitative experiment in electron scattering and the birth of scientific study of atomic and molecular phenomena by collisions. Today we recognize that electron-atom and electron- molecule collisions are prevalent across nature, describing disparate phenomena whilst the exploitation of such collisions underpins many of the technologies upon which modern society relies. The centenary of the Franck-Hertz experiment is thus a suitable opportunity to review both our current knowledge of electron interactions and to consider the directions of future research. In this article I therefore aim to both review our current state of knowledge and look forward, proposing that recent advances are providing something of a renaissance to the field and are vital for emerging technologies as well as answering some of the greatest scientific challenges of the 21st century
RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions
Monitoring of species' genetic diversity in Europe varies greatly and overlooks potential climate change impacts.
Genetic monitoring of populations currently attracts interest in the context of the Convention on Biological Diversity but needs long-term planning and investments. However, genetic diversity has been largely neglected in biodiversity monitoring, and when addressed, it is treated separately, detached from other conservation issues, such as habitat alteration due to climate change. We report an accounting of efforts to monitor population genetic diversity in Europe (genetic monitoring effort, GME), the evaluation of which can help guide future capacity building and collaboration towards areas most in need of expanded monitoring. Overlaying GME with areas where the ranges of selected species of conservation interest approach current and future climate niche limits helps identify whether GME coincides with anticipated climate change effects on biodiversity. Our analysis suggests that country area, financial resources and conservation policy influence GME, high values of which only partially match species' joint patterns of limits to suitable climatic conditions. Populations at trailing climatic niche margins probably hold genetic diversity that is important for adaptation to changing climate. Our results illuminate the need in Europe for expanded investment in genetic monitoring across climate gradients occupied by focal species, a need arguably greatest in southeastern European countries. This need could be met in part by expanding the European Union's Birds and Habitats Directives to fully address the conservation and monitoring of genetic diversity
Genetic variability in the Skyros pony and its relationship with other Greek and foreign horse breeds
In Greece, seven native horse breeds have been identified so far. Among these, the Skyros pony is outstanding through having a distinct phenotype. In the present study, the aim was to assess genetic diversity in this breed, by using different types of genetic loci and available genealogical information. Its relationships with the other Greek, as well as foreign, domestic breeds were also investigated. Through microsatellite and pedigree analysis it appeared that the Skyros presented a similar level of genetic diversity to the other European breeds. Nevertheless, comparisons between DNA-based and pedigree-based results revealed that a loss of genetic diversity had probably already occurred before the beginning of breed registration. Tests indicated the possible existence of a recent bottleneck in two of the three main herds of Skyros pony. Nonetheless, relatively high levels of heterozygosity and Polymorphism Information Content indicated sufficient residual genetic variability, probably useful in planning future strategies for breed conservation. Three other Greek breeds were also analyzed. A comparison of these with domestic breeds elsewhere, revealed the closest relationships to be with the Middle Eastern types, whereas the Skyros itself remained isolated, without any close relationship, whatsoever
Paternal Origins and Migratory Episodes of Domestic Sheep
Deng et al. show that domestic sheep harbor four Y chromosome lineages and early expansions of sheep were associated with the segregation of primitive and fat-tailed phenotypes as well as traits selected for different purposes
Does Genetic Diversity Predict Health in Humans?
Genetic diversity, especially at genes important for immune functioning within the Major Histocompatibility Complex (MHC), has been associated with fitness-related traits, including disease resistance, in many species. Recently, genetic diversity has been associated with mate preferences in humans. Here we asked whether these preferences are adaptive in terms of obtaining healthier mates. We investigated whether genetic diversity (heterozygosity and standardized mean d2) at MHC and nonMHC microsatellite loci, predicted health in 153 individuals. Individuals with greater allelic diversity (d2) at nonMHC loci and at one MHC locus, linked to HLA-DRB1, reported fewer symptoms over a four-month period than individuals with lower d2. In contrast, there were no associations between MHC or nonMHC heterozygosity and health. NonMHC-d2 has previously been found to predict male preferences for female faces. Thus, the current findings suggest that nonMHC diversity may play a role in both natural and sexual selection acting on human populations
Ethiopian indigenous goats offer insights into past and recent demographic dynamics and localadaptation in sub-Saharan African goats
Abstract Knowledge on how adaptive evolution and human socioâcultural and economic interests shaped livestock genomes particularly in subâSaharan Africa remains limited. Ethiopia is in a geographic region that has been critical in the history of African agriculture with ancient and diverse human ethnicity and bioâclimatic conditions. Using 52K genomeâwide data analysed in 646 individuals from 13 Ethiopian indigenous goat populations, we observed high levels of genetic variation. Although runs of homozygosity (ROH) were ubiquitous genomeâwide, there were clear differences in patterns of ROH length and abundance and in effective population sizes illustrating differences in genome homozygosity, evolutionary history, and management. Phylogenetic analysis incorporating patterns of genetic differentiation and gene flow with ancestry modelling highlighted past and recent intermixing and possible two deep ancient genetic ancestries that could have been brought by humans with the first introduction of goats in Africa. We observed four strong selection signatures that were specific to ArsiâBale and Nubian goats. These signatures overlapped genomic regions with genes associated with morphological, adaptation, reproduction and production traits due possibly to selection under environmental constraints and/or human preferences. The regions also overlapped uncharacterized genes, calling for a comprehensive annotation of the goat genome. Our results provide insights into mechanisms leading to genome variation and differentiation in subâSaharan Africa indigenous goats