Easy Scheme Outlining the Various Morphological and Vascular Abnormalities of the Lymph Node Structure Associated with Recent COVID-19 Vaccination, Each with a Different Clinical/Diagnostic Management

Throughout this recent ongoing SARS-CoV-2 pandemic, the European Society of Breast Imaging have surely contributed in improving the management of unilateral axillary adenopathy appearance homolaterally to the side of vaccine inoculation. After considering the patient's COVID-19 history of vaccination, our group produced a day-to-day scheme that evaluates meticulously the probability of mammary malignancy, according to the lymph node characteristics including vascular abnormalities. It comprises of a UN (ultrasound node) score ranging from 2 to 5, that increases with the suspicion of malignancy. In this setting and in view of the additional incoming COVID-19 boost-dose vaccinations, we believe our model could be of great utility to radiologist when assessing patients whom do not have a straight forward diagnosis, in order to reduce breast cancer missed diagnosis, avoid delaying vaccinations, reduce rescheduling of breast imaging examinations and lastly avoid unnecessary lymph node biopsies

Casimir scaling in G(2) lattice gauge theory

We computed potentials between static color sources from the six lowest representations of G(2) lattice gauge theory, in numerical simulations with the Wilson action on asymmetric lattices with nonperturbatively estimated values of the bare anisotropy. We present evidence for (approximate) Casimir scaling of the obtained intermediate string tensions. The agreement with the Casimir-scaling prediction improves by increasing the coupling beta in the weak-coupling region above the crossover observed in G(2) gauge theory. The result naturally fits into confinement models with magnetic disorder and vacuum domain structure, but may represent a challenge for other approaches.Comment: 14 pages, 12 figures (24 EPS files), RevTeX4. In v2: typos corrected, discussion of systematic errors and of smearing expanded, references added. Version to appear in Phys. Rev.

Lithium-Lead/water interaction: LIFUS5/Mod3 series E tests analysed by SIMMER-III coupled with RELAP5

The Breeding Blanket is a necessary component to close the nuclear fusion reactor fuel cycle. amongst the most promising conceptual design, there is the Water Cooled Lithium Lead Breeding Blanket, with water as coolant and eutectic Lithium-Lead as neutron multiplier and breeder. The possible interaction between water and Lithium-Lead poses a main safety concern and prompted the scientific community to develop a numerical analysis tool able to simulate such a complex interaction. The SIMMER-III code was modified by UNIPI to simulate the chemical interaction between water and Lithium-Lead, furthermore also a coupling methodology between SIMMER-III and RELAP5/Mod3.3 was developed. The coupling tool employs SIMMER-III code to simulate the zone of Lithium-Lead interacting with water, whilst the RELAP5 code is used to simulate the water pipelines. The LIFUS5/Mod3 facility at the ENEA Brasimone Research Centre was designed to perform reliable experimental activities on the interaction between water and Lithium-Lead. In this facility water at high pressure is injected inside a reaction vessel, where the thermodynamic and chemical interaction between water and Lithium-Lead occurs. The experimental activities are divided in different tests matrix, the Series D and Series E tests. The two series differ in the amount of water injected during the transient. In series D the mass of water is predetermined whilst in series E water was injected continuously for a pre-fixed interval of time and the total injected mass was estimated a posteriori. This work shows the results of the coupling tool applied to Series E. The comparison between the experimental and numerical results is performed by identifying and characterizing the phenomena involved in the interaction. Furthermore, the overall performance of the coupled codes in the simulation of the phenomena is presented here

Digital tomosynthesis spot view in architectural distortions: outcomes in management and radiation dose

Purpose To evaluate if digital breast tomosynthesis spot compression view (DBT-SCV) could be an additional projection to confirm or deny architectural distortions (ADs) detected by digital breast tomosynthesis (DBT) while assessing the average glandular radiation dose. Methods This is a retrospective cohort study enrolling 8864 DBT exams, of which only cases detecting primary AD and with BI-RADS 2-5 score were considered. Seventy-one AD cases examined with DBT-SCV, US and MRI were evaluated for correlation in terms of BI-RADS score; variables among exams were assessed for inter-relationships. Results Of all ADs identified at DBT, biopsy yielded malignancy in only 38%. PPV in identifying malignancy of ADs was higher for DBT-SCV than DBT (p < 0.05); the NPV of DBT-SCV was 94%. The difference between DBT and DBT-SCV in the detection of benign ADs was statistically significant (p < 0.05). AD without US or MRI confirmation was less likely to represent malignancy (p < 0.05). In detecting malignant cases of ADs, both DBT and DBT-SCV were strongly correlated with US and RM (Kappa > 0.90). In identifying benign cases of ADs, DBT-SCV was poorly/moderately correlated with US and RM (Kappa 0.25 and 0.66); DBT was negatively correlated with US and MRI. Conclusion DBT-SCV could be useful to better characterize AD firstly identified by DBT, keeping dose levels within the reference limits. If AD is detected by DBT without an US or MRI correlate, that is not confirmed by DBT-SCV, a "wait and see " approach can be applied to reduce unnecessary biopsy

New Frontiers in Managing Clival Tumors — The Extended Endoscopic Endonasal Approach

Clival lesions still represent a challenge for neurosurgeons. A variety of expansive process, either benign or malignant, may be identified in the clival and paraclival region

MAR-Mediated Dystrophin Expression in Mesoangioblasts for Duchenne Muscular Dystrophy Cell Therapy

A cornerstone of autologous cell therapy for Duchenne muscular dystrophy is the engineering of suitable cells to express dystrophin in a stable fashion upon differentiation to muscle fibers. Most viral transduction methods are typically restricted to the expression of truncated recombinant dystrophin derivatives and by the risk of insertional mutagenesis, while non-viral vectors often suffer from inefficient transfer, expression and/or silencing

Comments on large-N volume independence

We study aspects of the large-N volume independence on R**3 x L**G, where L**G is a G-site lattice for Yang-Mills theory with adjoint Wilson-fermions. We find the critical number of lattice sites above which the center-symmetry analysis on L**G agrees with the one on the continuum S**1. For Wilson parameter set to one and G>=2, the two analyses agree. One-loop radiative corrections to Wilson-line masses are finite, reminiscent of the UV-insensitivity of the Higgs mass in deconstruction/Little-Higgs theories. Even for theories with G=1, volume independence in QCD(adj) may be guaranteed to work by tuning one low-energy effective field theory parameter. Within the parameter space of the theory, at most three operators of the 3d effective field theory exhibit one-loop UV-sensitivity. This opens the analytical prospect to study 4d non-perturbative physics by using lower dimensional field theories (d=3, in our example).Comment: 12 pages; added small clarifications, published versio

Biochar powders coating to improve evaporative cooling in Maisotsenko-cycle systems

This work presents an experimental study on the performance of biochar powder coatings on aluminum surfaces for use in indirect evaporative coolers based on the Maisotsenko cycle. The performance of the biochar coated samples was compared to cellulose-coated aluminum samples and uncoated ones. Results showed that biochar coatings improved the performance of uncoated aluminum, with the 150 μm particle size coating offering performance comparable to cellulose. However, wetting times were longer, which has implications for spraying strategies