Kebutuhan Dan Pencarian Informasi Oleh Siswa Di Perpustakaan Smk Negeri 11 Semarang

Penelitian ini mengkaji tentang kajian pemakai perpustakaan. Penelitian ini sendiri untuk mengetahui kebutuhan dan pencarian informasi siswa dalam menelusur informasi yang dilakukan di Perpustakaan SMK Negeri 11 Semarang. Permasalahan yang dikaji adalah bagaimana kebutuhan dan pencarian informasi siswa di Perpustakaan SMK Negeri 11.Penelitian ini merupakan penelitian diskriptif kuantitatif dengan bentuk studi kasus, dengan populasi sejumlah 1517 orang siswa dan sampel sejumlah 160 orang siswa. Untuk memperoleh data yang valid penulis menggunakan beberapa metode pengumpulan data yaitu menggunakan angket/ kuesioner, observasi, dan wawancara. Untuk mengkatagorikan tingkat gejala yang diamati yaitu kebutuhan dan pencarian informasi siswa di Perpustakaan SMK Negeri 11 adalah dengan distribusi frekuensi. Hasil penelitian ini menunjukkan bahwa siswa membutuhkan sumber dan sarana informasi yang lain. Hal tersebut ditunjukkan dengan sebagian besar tujuan mereka berkunjung ke Perpustakaan SMK Negeri 11 untuk mengerjakan tugas dari guru. Adapun motivasi untuk datang ke Perpustakaan SMK Negeri 11, sebagian besar adalah karena menyelesaikan tugas yang sedang dikerjakan. Jenis informasi yang dibutuhkan responden adalah mapel .Bentuk informasi berupa buku teks yang dibutuhkan di perpustakaan. Pemanfaatan bahan pustaka khususnya buku yang dipinjam pada umumnya adalah antara 2 sampai dengan 4 buku dalam satu bulan. Selanjutnya cara penelusuran informasi yang dilakukan oleh hampir setengah siswa adalah mencari sendiri langsung ketempat koleksi dan hamper setengah siswa bertanya langsung ke petugas perpustakaan. Untuk upaya pencarian informasi selain di perpustakaan SMK Negeri 11, setengah dari siswa adalah mencari informasi yang sejenis melalui internet. Alasan siswa mencari di tempat lain adalah koleksi tidak ada dan hamper setengah yang lain sebagai bahan perbandingan koleksi yang lain

Heterogeneous Fenton's-like catalysis for degradation of colchicine coupled with extraction of its biologically active metabolite

Work performed in Professor Huddersman's laboratory at De Montfort University by visiting Researcher (academic lecturer) from Faculty of Pharmacy, Assiut University, Egypt The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Nowadays, drug pollution; a form of water pollution caused by some pharmaceuticals and their metabolites resulting from consumers, industry and hospitals was reported. Colchicine (CLN) is considered one of the pharmaceutical wastewater contaminants which are not eliminated completely in municipal sewage treatment plants and are discharged into receiving water. Due to the higher toxicity of CLN, a novel heterogeneous Fenton's-like catalysis was established for complete degradation of CLN. So, a highly sensitive and specific liquid chromatographic method with quadrupole mass spectrometry (LC/Q-MS) was developed and validated for estimation of CLN in its pure form and in the presence of its degradation product. Herein, GraceSmart RP C18 column was utilized for separation of the cited drug (Retention time tR= 5.578 min) using methanol: water (55: 45, v/v) at 1.0 mL/min. Detection was performed by Agilent 6120 Quadrupole MS detector in a positive ionization mode. Thereafter and for the first time, degradation of CLN by heterogeneous Fenton's-like catalysis using modified polyacrylonitrile (PAN) as a catalyst with H2O2 in aqueous acidic medium was performed. This process was firstly optimized by HPLC/UV detection at 248 nm using the aforementioned chromatographic conditions. As a result, CLN degraded completely within 30 min. The only observed degradation product was the biologically active, potent and less toxic antitumor metabolite of CLN (3- demethyl CLN) which was collected, extracted, and analyzed by Fourier Transfer- Infrared Spectroscopy (FTIR) and 13Carbon- Nuclear Magnetic Resonance (13C-NMR). Finally, this method is eco-friendly and complies with the requirements of the green chemistry. It is suitable for complete removal of CLN and/or its metabolite contaminants from wastewater samples and estimation of the target drug without any interference from its degradation products. However, further study is required to expand the method applicability to the pharmaceutical wastewater treatment as well the production of 3- demethyl CLN on a large scale

Surface Modification of Multilayer Coatings Ti-Al-Cr and Hydroxyapatite on Calcium Phosphate Cement with Sol-Gel Method

Dental implants based on metal still has weakness. New development is currently developed with the surface multilayer coatings Ti-Al-Cr and hydroxyapatite on calcium phosphate cement for dental implant application. Objective: to analyze the thickness of multilayer coating alloy Ti-Al-Cr and hydroxyapatite on CPC synthesis by sol-gel method. Methods: Scanning electron microscopy (SEM) was conducted to analyze the thickness and morphology of microstructure layer formed on CPC. Result: SEM showed that coating Ti-Al-Cr sucessfully formed 1 µm of thickness and 10 µm of hydroxyapatite. Conclusion: The innovation of modification surface multilayer coatings Ti-Al-Cr and hydroxyapatite on CPC was successfully done by sol-gel method with a variety thickness

Self-aligned nanoscale SQUID on a tip

A nanometer-sized superconducting quantum interference device (nanoSQUID) is fabricated on the apex of a sharp quartz tip and integrated into a scanning SQUID microscope. A simple self-aligned fabrication method results in nanoSQUIDs with diameters down to 100 nm with no lithographic processing. An aluminum nanoSQUID with an effective area of 0.034 $\mu$m$^2$ displays flux sensitivity of 1.8$\cdot 10^{-6}$ $\Phi_0/\mathrm{Hz}^{1/2} and operates in fields as high as 0.6 T. With projected spin sensitivity of 65$\mu_B/\mathrm{Hz}^{1/2}$ and high bandwidth, the SQUID on a tip is a highly promising probe for nanoscale magnetic imaging and spectroscopy.Comment: 14 manuscript pages, 5 figure

Health promoting potential of herbal teas and tinctures from Artemisia campestris subsp maritima: from traditional remedies to prospective products

This work explored the biotechnological potential of the medicinal halophyte Artemisia campestris subsp. maritima (dune wormwood) as a source of health promoting commodities. For that purpose, infusions, decoctions and tinctures were prepared from roots and aerial-organs and evaluated for in vitro antioxidant, anti-diabetic and tyrosinase-inhibitory potential, and also for polyphenolic and mineral contents and toxicity. The dune wormwood extracts had high polyphenolic content and several phenolics were identified by ultra-high performance liquid chromatography-photodiode array-mass-spectrometry (UHPLC-PDA-MS). The main compounds were quinic, chlorogenic and caffeic acids, coumarin sulfates and dicaffeoylquinic acids; several of the identified phytoconstituents are here firstly reported in this A. campestris subspecies. Results obtained with this plant's extracts point to nutritional applications as mineral supplementary source, safe for human consumption, as suggested by the moderate to low toxicity of the extracts towards mammalian cell lines. The dune wormwood extracts had in general high antioxidant activity and also the capacity to inhibit a-glucosidase and tyrosinase. In summary, dune wormwood extracts are a significant source of polyphenolic and mineral constituents, antioxidants and a-glucosidase and tyrosinase inhibitors, and thus, relevant for different commercial segments like the pharmaceutical, cosmetic and/or food industries.FCT - Foundation for Science and Technology [CCMAR/Multi/04326/2013]; Portuguese National Budget; FCT [IF/00049/2012, SFRH/BD/94407/2013]; Research Foundation - Flanders (FWO) [12M8315N]info:eu-repo/semantics/publishedVersio

Crassulacean Acid Metabolism Abiotic Stress-Responsive Transcription Factors: a Potential Genetic Engineering Approach for Improving Crop Tolerance to Abiotic Stress

This perspective paper explores the utilization of abiotic stress-responsive transcription factors (TFs) from crassulacean acid metabolism (CAM) plants to improve abiotic stress tolerance in crop plants. CAM is a specialized type of photosynthetic adaptation that enhances water-use efficiency (WUE) by shifting CO2 uptake to all or part of the nighttime when evaporative water losses are minimal. Recent studies have shown that TF-based genetic engineering could be a useful approach for improving plant abiotic stress tolerance because of the role of TFs as master regulators of clusters of stress-responsive genes. Here, we explore the use of abiotic stress-responsive TFs from CAM plants to improve abiotic stress tolerance and WUE in crops by controlling the expression of gene cohorts that mediate drought-responsive adaptations. Recent research has revealed several TF families including AP2/ERF, MYB, WRKY, NAC, NF-Y, and bZIP that might regulate water-deficit stress responses and CAM in the inducible CAM plant Mesembryanthemum crystallinum under water-deficit stress-induced CAM and in the obligate CAM plant Kalanchoe fedtschenkoi. Overexpression of genes from these families in Arabidopsis thaliana can improve abiotic stress tolerance in A. thaliana in some instances. Therefore, we propose that TF-based genetic engineering with a small number of CAM abiotic stress-responsive TFs will be a promising strategy for improving abiotic stress tolerance and WUE in crop plants in a projected hotter and drier landscape in the 21st-century and beyond

Improving the efficiency and stability of in-air fabricated perovskite solar cells using the mixed antisolvent of methyl acetate and chloroform

Antisolvents play a significant role in obtaining high-quality perovskite films during the fabrication process. This paper reports a novel mixture of two antisolvents (methyl acetate and chloroform) that proves effective for fabricating high-quality perovskite films in a high humidity ambient. The results show that the use of methyl acetate alone as the antisolvent enables the fabrication of dense perovskite films (MAPbI3) in a high humidity ambient, but with a rough surface, while mixing methyl acetate with an appropriate amount of chloroform produces not only dense perovskite films but also smooth surfaces. As a result, the power conversion efficiency (PCE) is increased from 17.1% of the devices treated with methyl acetate alone to 18.6% of the devices treated with the mixed antisolvent of methyl acetate (70%) and chloroform (30%). The stability of the devices was also improved significantly for the devices treated with the mixed antisolvent of methyl acetate (85%) and chloroform (15%), which exhibit a slow degradation of 7% in PCE after 552 h of storage, compared to 22% for the devices treated with methyl acetate alone

Glycerol valorization: dehydration to acrolein over silica-supported niobia catalysts

The catalytic dehydration of glycerol to acrolein is investigated over silica-supported niobia catalysts in a continuous fixed-bed gas-phase reactor. Various supported niobia catalysts are prepared and characterized using surface analysis and spectroscopic methods (XRD, UV–Vis, XPS, N2 adsorption), as well as with ammonia adsorption microcalorimetry. Good results are obtained with initial glycerol conversions of over 70% and with 50–70% selectivity to acrolein. We investigate the influence of changing the catalyst acid strength by varying the niobia content and catalyst calcination temperature. Glycerol conversion and acrolein selectivity depend on the surface acid strength. Catalyst deactivation by coking is also observed, but simple oxidative treatment in air restores the activity of the catalysts completely

ADAMTS19-associated heart valve defects: Novel genetic variants consolidating a recognizable cardiac phenotype

Recently, ADAMTS19 was identified as a novel causative gene for autosomal recessive heart valve disease (HVD), affecting mainly the aortic and pulmonary valves. Exome sequencing and data repository (CentoMD) analyses were performed to identify patients with ADAMTS19 variants (two families). A third family was recognized based on cardiac phenotypic similarities and SNP array homozygosity. Three novel loss of function (LoF) variants were identified in six patients from three families. Clinically, all patients presented anomalies of the aortic/pulmonary valves, which included thickening of valve leaflets, stenosis and insufficiency. Three patients had (recurrent) subaortic membrane, suggesting that ADAMTS19 is the first gene identified related to discrete subaortic stenosis. One case presented a bi-commissural pulmonary valve. All patients displayed some degree of atrioventricular valve insufficiency. Other cardiac anomalies included atrial/ventricular septal defects, persistent ductus arteriosus, and mild dilated ascending aorta. Our findings confirm that biallelic LoF variants in ADAMTS19 are causative of a specific and recognizable cardiac phenotype. We recommend considering ADAMTS19 genetic testing in all patients with multiple semilunar valve abnormalities, particularly in the presence of subaortic membrane. ADAMTS19 screening in patients with semilunar valve abnormalities is needed to estimate the frequency of the HVD related phenotype, which might be not so rare