Pengaruh Ekstrak Kulit Jeruk Pamelo terhadap Infeksi Jamur Fusarium Oxysporum pada Tanaman Tomat

Jeruk Pamelo (Citrus grandis) memiliki kandungan senyawa kimia aktif berupa limonen 90% yang tertinggi dibandingkan dengan jenis jeruk lainnya. Limonen merupakan senyawa terpenoid yang dapat dimanfaatkan sebagai fungisida nabati. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi ekstrak jeruk Pamelo terhadap pertumbuhan tomat yang terinfeksi Fusarium oxysporum. Parameter yang diamati meliputi tinggi tanaman dan tingkat infeksi pada akar tomat. Ekstrak diambil dengan metode maserasi dan diaplikasikan pada tanaman umur 43 hst hingga 49 hst dengan konsentrasi 1%, 3%, 5%, 7% dan 9%. Infeksi patogen F. oxysporum pada tomat dilakukan saat umur 40 hst selama 48 jam diinkubasi dalam greenhouse. Hasil penelitian menunjukkan bahwa pemberian ekstrak kulit jeruk Pamelo tidak berbeda nyata secara signifikan terhadap pertumbuhan tinggi batang tanaman tomat, namun pada pengamatan infeksi akar menunjukkan bahwa pemberian ekstrak konsentrasi 1% mampu menghambat infeksi jamur F. oxysporum yang sebanding dengan fungisida kimia sintesis Antracol 0,3 %

EFFICIENCY OF ULTRAFILTRATION CERAMIC MEMBRANES FOR TOXIC ELEMENTS REMOVAL FROM WASTEWATERS

The preparation and characterization of porous ceramics multilayer ultrafiltration membrane is described. The first step consisted to prepare high-quality macroporous support in Moroccan clay. The choice of this material is based on its natural abundance and thermal stability.The microporous interlayer was then prepared by slip casting from zirconia commercial powders and finally the active UF toplayers was obtained by sol-gel route using ZnAl2O4 and TiO2 mixed sols. The performance of ultrafiltration membrane (TiO2 (50�20– ZnAl2O4 (50� was evaluated by pores diameter, water flux, thickness and molecular weight cut off (MWCO). The water permeability measured for this composite membrane is 9.42 L/(m2•h•bar), the thickness is less than 700 nm, the pore diameter is centered near 5 nm and the MWCO was about 4500 Da

Quantum Critical Point in the Spin Glass-Kondo Transition in Heavy Fermion Systems

The Kondo-Spin Glass competition is studied in a theoretical model of a Kondo lattice with an intra-site Kondo type exchange interaction treated within the mean field approximation, an inter-site quantum Ising exchange interaction with random couplings among localized spins and an additional transverse field in the x direction, which represents a simple quantum mechanism of spin flipping. We obtain two second order transition lines from the spin-glass state to the paramagnetic one and then to the Kondo state. For a reasonable set of the different parameters, the two second order transition lines do not intersect and end in two distinct QCP.Comment: 20 pages; 1 figure; to appear in Physical Review

The epidemiology of HIV infection in Morocco: systematic review and data synthesis.

Morocco has made significant strides in building its HIV research capacity. Based on a wealth of empirical data, the objective of this study was to conduct a comprehensive and systematic literature review and analytical synthesis of HIV epidemiological evidence in this country. Data were retrieved using three major sources of literature and data. HIV transmission dynamics were found to be focused in high-risk populations, with female sex workers (FSWs) and clients contributing the largest share of new HIV infections. There is a pattern of emerging epidemics among some high-risk populations, and some epidemics, particularly among FSWs, appear to be established and stable. The scale of the local HIV epidemics and populations affected show highly heterogeneous geographical distribution. To optimize the national HIV response, surveillance and prevention efforts need to be expanded among high-risk populations and in geographic settings where low intensity and possibly concentrated HIV epidemics are emerging or are already endemic

Seismic risk in the city of Al Hoceima (north of Morocco) using the vulnerability index method, applied in Risk-UE project

The final publication is available at Springer via http://dx.doi.org/10.1007/s11069-016-2566-8Al Hoceima is one of the most seismic active regions in north of Morocco. It is demonstrated by the large seismic episodes reported in seismic catalogs and research studies. However, seismic risk is relatively high due to vulnerable buildings that are either old or don’t respect seismic standards. Our aim is to present a study about seismic risk and seismic scenarios for the city of Al Hoceima. The seismic vulnerability of the existing residential buildings was evaluated using the vulnerability index method (Risk-UE). It was chosen to be adapted and applied to the Moroccan constructions for its practicality and simple methodology. A visual inspection of 1102 buildings was carried out to assess the vulnerability factors. As for seismic hazard, it was evaluated in terms of macroseismic intensity for two scenarios (a deterministic and probabilistic scenario). The maps of seismic risk are represented by direct damage on buildings, damage to population and economic cost. According to the results, the main vulnerability index of the city is equal to 0.49 and the seismic risk is estimated as Slight (main damage grade equal to 0.9 for the deterministic scenario and 0.7 for the probabilistic scenario). However, Moderate to heavy damage is expected in areas located in the newer extensions, in both the east and west of the city. Important economic losses and damage to the population are expected in these areas as well. The maps elaborated can be a potential guide to the decision making in the field of seismic risk prevention and mitigation strategies in Al Hoceima.Peer ReviewedPostprint (author's final draft

Safety and efficacy of glecaprevir/pibrentasvir in patients with chronic hepatitis C genotypes 1-6 receiving opioid substitution therapy

Background: International guidelines recommend treatment of hepatitis C virus (HCV) infection in people who inject drugs (PWID), including those on opioid substitution therapy (OST). The pangenotypic combination of glecaprevir and pibrentasvir has shown high sustained virologic response at post-treatment Week 12 (SVR12) in clinical trials. Herein, we evaluate the safety and efficacy of glecaprevir/pibrentasvir in patients receiving OST. Methods: Pooled data from patients with HCV genotypes 1–6 who were treated with glecaprevir/pibrentasvir for 8, 12, or 16 weeks in eight Phase 2 and 3 trials were categorized by use of OST. Treatment completion, treatment adherence, SVR12, adverse events (AEs), and laboratory abnormalities were evaluated for patients receiving and not receiving OST. Results: Among 2256 patients, 157 (7%) were receiving OST. Compared with patients not receiving OST, OST patients were younger (mean age, 46.8 vs 52.8 years), male (69% vs 54%), white (93% vs 80%), HCV treatment-naïve (86% vs 72%), had HCV genotype 3 (60% vs 26%), and had a history of depression or bipolar disorder (43% vs 19%). Most patients completed (OST: 98% [n/N = 154/157]; non-OST: 99% [n/N = 2070/2099]) and were adherent (received ≥90% of study drug doses) to glecaprevir/pibrentasvir treatment (OST: 98% [n/N = 121/123]; non-OST: 99% [n/N = 1884/1905] among patients with available data). In the intention-to-treat population, SVR12 rates in OST and non-OST patients were 96.2% (n/N = 151/157; 95% CI 93.2–99.2) and 97.9% (n/N = 2055/2099; 95% CI 97.3–98.5), respectively. For OST patients, reasons for nonresponse included virologic relapse (&lt;1%; n = 1), premature study drug discontinuation (&lt;1%; n = 1), and loss to follow-up (3%; n = 4). AEs occurring in ≥10% of OST patients were headache, fatigue, and nausea. Drug-related serious AEs, AEs leading to study drug discontinuation, and Grade 3 or higher laboratory abnormalities were infrequent in both groups (&lt;1%). No HCV reinfections occurred through post-treatment Week 12. Conclusion: Glecaprevir/pibrentasvir is highly efficacious and well tolerated in HCV-infected patients receiving OST.</p

Masse atypique du rhinopharynx : chondrome sphénoïdal

Le chondrome est une tumeur bénigne cartilagineuse dont la localisation sphénoïdale est exceptionnelle. Cette tumeur pose des problèmes diagnostiques et thérapeutiques considérables. Observation : nous rapportons le cas d’une femme de 59 ans, présentant un chondrome sphénoïdal étendu et révélé exclusivement par une obstruction nasale bilatérale. Une résection chirurgicale complète a été réalisée par voie endoscopique endonasale. aucune récidive n’est survenue après 14 mois de suivi. Discussion : Le chondrome sphénoïdal est dangereux par son extension aux structures vasculonerveuses de voisinage. Chondrome et chondrosarcome sont souvent difficiles à différencier. endoscopie et neuronavigation améliorent significativement la qualité de l’exérèse. Le risque de récidive impose un suivi prolongé.Mots clefs : chondrome, chondrosarcome, sphénoïdeIntroduction: the sphenoidal Chondroma is exceptional. This tumor raises significant diagnostic and therapeutic problems.Case report: We report the case of a 59 year old woman, with a large sphenoidal chondroma revealed exclusively by bilateral nasal obstruction. Complete endoscopic endonasal resection was performed. no recurrence occurred after 14 months of follow-up. Discussion: The sphenoidal chondroma is dangerous by its extension to neurovascular structures.Chondroma and chondrosarcoma are often difficult to differentiate. endoscopy and neuronavigation significantly improve the quality of resection. The risk of recurrence requires prolonged follow-up.Keywords : chondroma ; chondrosarcoma ; sphenoid bon

Masse atypique du rhinopharynx : chondrome sphenoïdal

Introduction: Le chondrome est une tumeur bénigne cartilagineuse dont la localisation sphénoïdale est exceptionnelle. Cette tumeur pose des problèmes diagnostiques et thérapeutiques considérables.Observation : Nous rapportons le cas d’une femme de 59 ans, présentant un chondrome sphénoïdal étendu et révélé exclusivement par une obstruction nasale bilatérale. Une résection chirurgicale complète a été réalisée par voie endoscopique endonasale. Aucune récidive n’est survenue après 14 mois de suivi.Discussion : Le chondrome sphénoïdal est dangereux par son extension aux structures vasculo-nerveuses de voisinage. Chondrome et chondrosarcome sont souvent difficiles à différencier. Endoscopie et neuronavigation améliorent significativement la qualité de l’exérèse. Le risque de récidive impose un suivi prolongé.Mots clés : chondrome, chondrosarcome, sphénoïdeIntroduction : the sphenoidal Chondroma is exceptional. This tumor raises significant diagnostic and therapeutic problems.Case report : We report the case of a 59 year old woman, with a large sphenoidal chondroma revealed exclusively by bilateral nasal obstruction. Complete endoscopic endonasal resection was performed. No recurrence occurred after 14 months of follow-up.Discussion : The sphenoidal chondroma is dangerous by its extension to neurovascular structures. Chondroma and chondrosarcoma are often difficult to differentiate. Endoscopy and neuronavigation significantly improve the quality of resection. The risk of recurrence requires prolonged follow-up.Key words : chondroma ; chondrosarcoma ; sphenoid bon

Création participative du Parc naturel de Bouhachem (Maroc) -

Dans le cadre de la Semaine forestière méditerranéenne d'Avignon, l'Association Internationale Forêts Méditerranéennes (AIFM) et le Plan Bleu 1, ont organisé trois sessions sur le thème "Forêt, sociétés et territoires". Ces sessions avaient pour objectif de promouvoir une approche territoriale et intersectorielle de la gestion forestière et des initiatives d'amélioration de la gouvernance forestière. Elles se sont appuyées sur la présentation d'expériences territoriales de gestion participative, comme ici, l'exemple de la création du Parc naturel régional de Bouhachem au Maroc