RISK FACTORS AND CRITERIA FOR PREDICTION OF OVARIAN HYPERSTIMULATION SYNDROME

Ovarian hyperstimulation syndrome (OHSS) is the most frequent and dangerous complication of IVF programmers. Evaluation of OHSS risk factors allows to perform differentiated, approaches to controlled ovarian stimulation. This article presents the results of OHSS risk factors analysis in 775 IVF cycles. It was found that young age (< 35 years), PCOS, tubal factor of infertility and low BMI (< 25 kg/m2) are the significant risk factors for OHSS

ESTIMATION OF EFFICIENCY OF A TECHNIQUE OF TRANSVAGINAL PUNCTURES OF OVARIES WITH WASHING OF FOLLICLES IN IVF CYCLES

«Poor» ovarian response in standard IVF protocols leads to the difficulty or even impossibility of ensuring the stage of transfer of embryos. A technique of transvaginal puncture with washing of follicles by buffer solution is performed in patients with «poor» ovarian response. This article presents the analysis of TVP in 495 IVF initiated treatment cycles. A smaller number of mature oocytes and embryos are received in the process of controlled ovarian hyperstimulation in patients with washing of follicles, however, the possibility of pregnancy is comparable to the overall IVF results

Determination of the orbital moment and crystal field splitting in LaTiO3_{3}

Utilizing a sum-rule in a spin-resolved photoelectron spectroscopic experiment with circularly polarized light, we show that the orbital moment in LaTiO$_3$ is strongly reduced both below and above the N\'{e}el temperature. Using Ti $L_{2,3}$ x-ray absorption spectroscopy as a local probe, we found that the crystal field splitting in the $t_{2g}$ subshell is about 0.12-0.30 eV. This large splitting does not facilitate the formation of an orbital liquid

Analysis of the efficiency of IFV techniques (ICSI, PICSI) in the assisted reproductive technology programs

The male factor is the cause of infertility in 40 % of cases. This study is dedicated to the efficiency assessment of ICSI and PICSI techniques and the determination of indications of these methods. There are some relative indicationsfor ICSI in clinical practice: advanced reproductive age of patients, a small number of obtained oocytes, prolonged infertility, repeated attempts of in vitro fertilization. However, normal sperm values are registered in 71.3 % of cases. PICSI method is more preferable at high level of DNA fragmentation and associated changes in sperm indicators. Nevertheless, the pregnancy rate after these methods was comparable - 19.3 % and 19.7 % respectively. The results indicate that the ICSI and PICSI methods do not have a negative impact on the quality of the embryos and do not increase the pregnancy rate

Estimation and analysis of multi-GNSS differential code biases using a hardware signal simulator

In ionospheric modeling, the differential code biases (DCBs) are a non-negligible error source, which are routinely estimated by the different analysis centers of the International GNSS Service (IGS) as a by-product of their global ionospheric analysis. These are, however, estimated only for the IGS station receivers and for all the satellites of the different GNSS constellations. A technique is proposed for estimating the receiver and satellites DCBs in a global or regional network by first estimating the DCB of one receiver set as reference. This receiver DCB is then used as a ‘known’ parameter to constrain the global ionospheric solution, where the receiver and satellite DCBs are estimated for the entire network. This is in contrast to the constraint used by the IGS, which assumes that the involved satellites DCBs have a zero mean. The ‘known’ receiver DCB is obtained by simulating signals that are free of the ionospheric, tropospheric and other group delays using a hardware signal simulator. When applying the proposed technique for Global Positioning System legacy signals, mean offsets in the order of 3 ns for satellites and receivers were found to exist between the estimated DCBs and the IGS published DCBs. It was shown that these estimated DCBs are fairly stable in time, especially for the legacy signals. When the proposed technique is applied for the DCBs estimation using the newer Galileo signals, an agreement at the level of 1–2 ns was found between the estimated DCBs and the manufacturer’s measured DCBs, as published by the European Space Agency, for the three still operational Galileo in-orbit validation satellites

Population genomics of post-glacial western Eurasia.

Western Eurasia witnessed several large-scale human migrations during the Holocene &lt;sup&gt;1-5&lt;/sup&gt; . Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced 317 genomes-mainly from the Mesolithic and Neolithic periods-from across northern and western Eurasia. These were imputed alongside published data to obtain diploid genotypes from more than 1,600 ancient humans. Our analyses revealed a 'great divide' genomic boundary extending from the Black Sea to the Baltic. Mesolithic hunter-gatherers were highly genetically differentiated east and west of this zone, and the effect of the neolithization was equally disparate. Large-scale ancestry shifts occurred in the west as farming was introduced, including near-total replacement of hunter-gatherers in many areas, whereas no substantial ancestry shifts happened east of the zone during the same period. Similarly, relatedness decreased in the west from the Neolithic transition onwards, whereas, east of the Urals, relatedness remained high until around 4,000 BP, consistent with the persistence of localized groups of hunter-gatherers. The boundary dissolved when Yamnaya-related ancestry spread across western Eurasia around 5,000 BP, resulting in a second major turnover that reached most parts of Europe within a 1,000-year span. The genetic origin and fate of the Yamnaya have remained elusive, but we show that hunter-gatherers from the Middle Don region contributed ancestry to them. Yamnaya groups later admixed with individuals associated with the Globular Amphora culture before expanding into Europe. Similar turnovers occurred in western Siberia, where we report new genomic data from a 'Neolithic steppe' cline spanning the Siberian forest steppe to Lake Baikal. These prehistoric migrations had profound and lasting effects on the genetic diversity of Eurasian populations

Early neolithic ceramics of Western Siberia (thermal analysis results)

The article discusses the results of thermal analysis (DTG) of ceramic vessels samples from archaeological sites of Baraba and the Lower Ob region of the Early Neolithic period. The DTG technique is based on the quantitative determination of mass loss by a sample at the stages of dehydration - mass loss within the temperature interval between 30-350°C (m1) and decomposition of hydroxyls - mass loss within the interval between 350-600°C (m2). The data are visualized by a graph. Attention is focused on comparing the location of the indicators of the samples from the Tartas-1, Ust-Tartas-1, Autodrom-2/1 and 2/2, Amnya-1, Kirip-Vis-Yugan-2 sites. The authors establish the possibility of using the thermal method for fixing - based on determining the quality of firing - ancient ceramic complexes. It is revealed that the items of the studied sites were subjected to short-term low-temperature firing. The ceramics of the Amnya-1, Kirip-Vis-Yugan-2 sites was divided into two groups. One of them demonstrates the isolation of crockery from the northern regions and its gravitation towards a group with ancient Far Eastern ceramics, which may be the result of the convergent development of pottery production. © 2019 Institute of History and Archeology of the Ural Branch of RAS. All rights reserved