Laparoscopic Radical Nephrectomy: The New Gold Standard Surgical Treatment for Localized Renal Cell Carcinoma

We will try to demonstrate that laparoscopic radical nephrectomy could be the new gold standard treatment for renal cell carcinoma with the aid of the current reports exploring the advantages and disadvantages of laparoscopic radical nephrectom overopen surgery

Comparison of the Heavy Metal Concentrations in Atlantic Horse Mackerel, Trachurus Trachurus, from Coastal Waters of Turkey

Turkmen, Mustafa/0000-0001-6700-5947; TEPE, Yalcin/0000-0002-8415-3754; Turkmen, Aysun/0000-0001-7461-4038; TEPE, Banu/0000-0002-3428-8167WOS: 000302925100011The concentrations of cadmium, iron, lead, zinc, copper, manganese, nickel, chromium and cobalt were determined by ICP-AES in muscles and livers of Atlantic horse mackerel, Trachurus trachurus, from coastal waters of Turkey. The analyzed fish samples were collected from different locations in the Black, Marmara, Aegean and Mediterranean seas. The heavy metal concentrations in tissues were significantly affected by sampling sites (p<0.05). Iron showed the highest levels in both tissues from all locations, followed by Zn. In all locations, the heavy metal concentrations in livers were higher than those in muscles. In addition, the differences between the heavy metal concentrations in tissues were statistically significant (p<0.05). Heavy metal levels in tissues were compared with national and international permissible limits. Heavy metal concentrations in the edible parts of fish were assessed for human uses.Scientific & Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [105Y018]The authors thank The Scientific & Technological Research Council of Turkey for their financial support (Project No: 105Y018)

Comparison of the heavy metal concentrations in atlantic horse mackerel, trachurus trachurus, from coastal waters of turkey

The concentrations of cadmium, iron, lead, zinc, copper, manganese, nickel, chromium and cobalt were determined by ICP-AES in muscles and livers of Atlantic horse mackerel, Trachurus trachurus, from coastal waters of Turkey. The analyzed fish samples were collected from different locations in the Black, Marmara, Aegean and Mediterranean seas. The heavy metal concentrations in tissues were significantly affected by sampling sites (p< 0.05). Iron showed the highest levels in both tissues from all locations, followed by Zn. In all locations, the heavy metal concentrations in livers were higher than those in muscles. In addition, the differences between the heavy metal concentrations in tissues were statistically significant (p<0.05). Heavy metal levels in tissues were compared with national and international permissible limits. Heavy metal concentrations in the edible parts of fish were assessed for human uses. by psp

The impact of bladder neck sparing on urinary continence during laparoscopic radical prostatectomy; Results from a high volume centre

Objective: To evaluate the effects of bladder neck reconstruction techniques on early continence after laparoscopic radical prostatectomy (LRP). Materials and methods: This non-randomized retrospective study analyzed prospectively collected data concerning LRP. In total, 3107 patients underwent LRP between March 1999 and December 2016. Exclusion criteria were preoperative urinary incontinence, previous history of external beam radiotherapy, co-morbities which may affect urinary continence such as diabetes mellitus and/or neurogenic disorders, irregular followup, and follow-up shorter than 24 months. All patients were divided into one of three groups, posterior reconstruction being performed in Group 1 (n = 112), anterior reconstruction in Group 2 (n = 762), and bladder neck sparing (BNS) in Group 3 (n = 987). Demographic and pre-, peri-, and postoperative data were collected. Multivariate analyses were performed to determine factors affecting early continence after LRP. Results: 1861 patients were enrolled in the study. The mean follow-up period was 48.12 ± 29.8 months, and subjects’ mean age was 63.6 ± 6.2 years. There was no significant difference among the groups in terms of demographic or preoperative data. Postoperative data, including oncological outcomes, were similar among the groups. The level of early continence was higher in Group 3 than in the other groups (p &lt; 0.001). Multivariate analyses identified BNS and age as parameters significantly affecting early continence levels after LRP (p &lt; 0.001 and p &lt; 0.001, respectively). Bladder neck reconstruction provided less earlier continence than BNS

Percutaneous Muscular Ventricular Septal Defect Closure with 2D Transthoracic Echocardiography: Can We Sufficiently Visualize It?

Ventricular septal defect (VSD) is one of the most common congenital heart diseases worldwide today. Although the majority close spontaneously, transcatheter VSD closure is a common option for symptomatic patients with suitable anatomy in adult age. Although transesophageal echocardiography (TEE) and intracardiac echocardiography are the most common imaging modalities for the procedure, in patients with poor TEE images, Transthoracic echocardiography (TTE) can be used as a reliable alternative. Here we present an adult patient with pulmonary hypertension associated with a muscular VSD which was closed percutaneously using 2-dimensional TTE because of poor TEE images

RELATIONSHIP BETWEEN MASKED ARTERIAL HYPERTENSION AND ERECTILE DYSFUNCTION

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Factors affecting surgical margin positivity in robotic assisted radical prostatectomy

Objectives: After radical prostatectomy, surgical margin positivity is an important indicator of biochemical recurrence and progression. In our study we want to compare the surgical margin positivity rates for retropubic radical prostatectomy (RRP) and robotic assisted radical prostatectomy (RALP) and investigate the factors affecting surgical margin positivity in RALP. Materials and methods: Data from 78 RRP and 62 RALP patients operated from 2011 May to 2016 March were retrospectively screened. Patients in both groups were compared in terms of age, postop hematocrit reduction, hospital stay, duration of follow-up, surgical margin positivity, biochemical recurrence and oncologic parameters. In RALP group it was searched the relationship between the surgical margin positivity and prostate specific antigen (PSA), positive biopsy core, biopsy Gleason scoring, pathologic stage and Gleason scoring, lymph node positivity, lymphovascular and perineural invasion, extracapsular extension, seminal vesicle invasion, prostate weight. Results: Patients in the RALP group had lower postop hematocrit reduction and shorter hospital stay (p &lt; 0.001). There was no difference in surgical margin positivity between RALP and RRP groups (37.1% vs. 29.5%, p = 0.341). In RALP group there was a correlation between surgical margin positivity and positive biopsy core number (p = 0.011), pathologic stage (p &lt; 0.001) and Gleason score (p &lt; 0.001), EAU risk classification (p = 0.001), seminal vesicle invasion (p = 0.045), extraprostatic extension (p &lt; 0.001). There was no correlation between prostate weight (p = 0.896), PSA (p = 0.220), biopsy Gleason score (p = 0.266), lymph node positivity (p = 0.140), perineural (p = 0.103) and lymphovascular invasion (p = 0.92) with surgical margin positivity. Conclusions: Positive biopsy core number, pathological stage and Gleason score, EAU risk classification, seminal vesicle invasion and extraprostatic extension are correlated with surgical margin positivity in RALP

Management Patterns of Male Urethral Stricture Disease among Urologists: What Do the Guidelines Say? What Do Urologists Do?

BACKGROUND: The aim of the present study is to evaluate and analyze the daily clinical practice for male urethral stricture disease (MUSD) among urologists. METHODS: Considering the latest guidelines on urethral stricture disease, a survey was developed regarding the various treatment options and preferences in different sites of male urethral stricture disease. The survey was sent to urologists via e-mail and phone application. RESULTS: A total of 266 urologists completed the survey and were included in the final analysis. In regard to workplace, 62 (23.3%), 58 (21.8%), 71 (26.7%), and 75 (28.2%) respondents worked in university hospitals, training and research hospitals, state hospitals, and private practice hospitals, respectively. In regard to the diagnostic method used in male urethral strictures, 88.7% of the participants would choose uroflowmetry + postvoiding residual (UF + PVR), and 64.6% would choose retrograde urethrography (RUG). Direct vision internal urethrotomy (DVIU) was the most frequently chosen method in penile urethral strictures (PUS), being chosen by 72.9%. Direct vision anterior internal urethrotomy was the most common method for both ≤2 cm and >2 cm strictures, 63.1%, and 30.8%, respectively. The most preferred graft for augmentation urethroplasty was buccal mucosa (75.8%). Endoscopic incision/resection (transurethral resection (TUR)) is the most frequently applied treatment method for posterior urethral/vesicourethral anastomotic strictures (86.4%). CONCLUSIONS: The present study clearly shows that most urologists still prefer DVIU and urethral dilatation to urethroplasty in MUSD, which contradicts current guidelines. Urologists should be encouraged to perform urethroplasty and/or refer patients to experienced centres for recurrent MUSD

The effect of the ischaemic compression technique on pain and functionality in temporomandibular disorders: A randomised clinical trial

Background: Interventions addressing pain and impaired functionality in individuals with temporomandibular disorders (TMDs) are needed