Drawing is Learning

JAEPL’s guru of visual pedagogy visits the origins of his strategy for teaching through “handmade thinking,” which gives students the freedom to re-conceptualize how they read and write

Connecting

Finding Meaning in our Work and Writing, Christy I. Wenger Response from Beyond, Monica Mische Reflecting on Arguing and Listening in Digital Spaces, Kristina Fennelly Sunday Morning Before Midterms, Laurence Musgrove Honoring Impulse, Attending to Gesture, Lindsey All-goo

Connecting

Christy Wenger - Risks and Rewards of Purposeful Vulnerability Christina Martorana - Embracing Vulnerability in Teaching Jacquelyn E. Hoerman-Elliott - Writing as a Sea of Oms: A “This I Believe” Essay for Contemplative Writing in First-Year Composition Beth Godbee and Adrianne Wojcik - Decoding Each Other through Coding: Sharing Our Unlikely Research Collaboration Laurence Musgrove - Dress Up Laurence Musgrove - Tree

Connecting

Connecting Helen Walker - Teaching/Seeing Jesus Jan Buley - The Realization S. Rebecca Leigh - Celebrating Ways of Learning Christopher M. Bache - The Opening Question Bette B. Bauer - Teaching as a Spiritual Practice Rachel Forrester - Appalachia Finally in the Spring Laurence Musgrove - Syllabu

Connecting

Helen Walker - More Apt, Connected Title Sheryl Lain - Hey, Teach! Do You Love Me? Matthew B. Ittig - Ask Me Tomorrow Laurence Musgrove - Writing Program Julie O’Connell - The Power of a Slave Narrative Leslie A. Werden - Embracing Chaos Donna Souder-Hodge - Teaching Dachau Tanya R. Cochran, Rasha Diab, Thomas Ferrel, & Beth Godbee - Hanging Out: Cultivating Life-Giving Writing Groups Onlin

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts

What Happens When We Read: Picturing a Reader’s Responsibilities

A graphic representation of reading as a process enables students to respond more fully and responsibly to literature by attending to what they contribute to the act of reading, what the world to the text can offer, what kinds of responses are available to them, and what they can do to make sure they have responded as thoughtfully as possible

Attitudes Toward Writing

This essay describes one teacher\u27s approach to helping students understand the role attitude plays in contributing to or interfering with success in the writing class

Connecting

Connecting - Helen Walker Louise Morgan - Email about the Ego Danielle Sahm - The Poet Rewritten Laurence Musgrove - People Get Ready Rae Ann De Rosse - Authority Issues Joonna Smitherman Trapp - The Importance of Being Ernie Beverly Faxon - Why I Read Them Poetr