Childhood-Onset Obsessive Compulsive Disorder

Childhood-onset obsessive-compulsive disorder affects 1%-2% of children and adolescents. While symptoms reported by children and behavioral therapies and pharmacological interventions administered to children are similar to those seen among individuals who develop obsessive compulsive disorder in adulthood, there are several differences with regards to sex ratios, comorbidity patterns, neuroimaging findings. Family and twin studies support the role of genetics in some forms of obsessive compulsive disorder. Prefrontal cortex, cingulate cortex, thalamus, nucleus caudatus, putamen and globus pallidus are the main brain areas affected in children with obsessive compulsive disorder. Selective serotonin reuptake inhibitors (SSRI) are the treatment of choice for pharmacotherapy of obsessive compulsive disorder and exposure and response prevention are the most commonly applied behavioral therapy methods in obsessive compulsive disorder. Despite advances in the treatment of the disorder, obsessive compulsive disorder is still considered as a debilitating chronic disorder

Organizational Commitment of People Working For Turkish Sports Management Organizations In Terms of Some Variables

The aim of this study is to identify and examine the organizational commitment levels of the people working for General Directorate of Sports and Sports Federations that form the main structure of Turkey national sports management organization regarding some variables. Sampling of the study consisted of 105 female and 142 male, totally 247 participants whose age averages were 40.53± 9.86 working for General Directorate of Sports and Sports Federations that form the main structure of Turkish national sports management organization. Organizational Commitment Questionnaire (OCQ) was used to identify organizational commitment levels of the employers. Since the data did not meet the parametric hypotheses, nonparametric Kruskall-Wallis and Man-Whitney U tests were used to analyze organizational commitment levels in terms of variables. Results of the analysis revealed that organizational commitment and its sub dimensions emotional, normative and attendance commitment levels were at moderate level. Considering education levels, getting in-service training and quality inservice training conditions, there was not any significant difference at organizational commitment level and sub dimensions; however, there were significant differences in terms of the ages, marital statuses, the institution they worked for, their position, and whether they chose their job voluntarily or not. In conclusion, the ones who were above 40, married, working for federation, chose their jobs voluntarily, were senior executives, and section leaders had higher organizational commitment levels

Job Satisfaction Level Of Government Employees: The General Directorate Of Sport And Sports Federations Sample

The purpose of this study is to determine the job satisfaction levels of employees of sports federation and general directorate of sport, and to analyze according to some variables. “Minnesota Job Satisfaction Questionnaire” was used to determine the job satisfaction levels of employees. Since the data didn’t fulfill the parametric assumptions, nonparametric Kruskall-Wallis and Man-Whitney U tests were used on the analysis according to job satisfaction levels. According to results of analysis, 98.8% of employees’ job satisfaction levels are medium and high. It was revealed that there is a statistically significant difference between employees’ general job satisfaction, internal and external sub-dimension points according to age groups, marital status, situation of selecting their jobs willingly and educational level. As a result; it was seen in terms of general job satisfaction and internal satisfaction that internal satisfaction levels of employees who are 40 or more in comparison with employees who are between 22-40 age groups, internal satisfaction levels of employees whose marital status are married in comparison with employees whose marital status are single, general satisfaction and internal satisfaction levels of employees who selected their job willingly and general, internal and external satisfaction levels of employees whose education levels are associate degree in comparison with employees whose education levels are bachelor’s degree and postgraduate are higher

Knowledge and understanding risk factors and preventive measures for osteoporosis in women: results of a survey in 502 women with and without a migration background

Background: Osteoporosis is a disease of the skeletal system associated with loss of bone mass and an increased risk of fractures affecting women more often than men. Identification of the knowledge about osteoporosis and its preventive methods is the backbone of any awareness program. This study investigates the knowledge with a special focus on women with and without a migration background. Methods: Data from systematic patient interviews based on a questionnaire were collected at three different sites in Berlin between February and June 2021. The survey included questions assessing migrant background, demographic characteristics, lifestyle habits including physical exercise and smoking, prevention by vitamin D intake and bone densitometry, and information on personal and family medical history. According to the responses, a scale was created to assess the level of knowledge of preventive osteoporosis measures. The ethic committee of the Charite, Medical faculty has approved this study. SPSS (version 24.0) was used for the statistical analyses. Results: The survey of 502 female patients revealed that 25% had low and 34% no previous knowledge of osteoporosis. Older age and a better education level correlate with a higher knowledge. Patients with gynecologic cancer are less well informed. There is a significant difference in vitamin D intake between migrant and non-migrant women (57% vs. 49%). There were no significant differences regarding the use of bone densitometry. Conclusion: Knowledge of osteoporosis and the possibility of a bone densitometry as well as the implementation of preventive measures is low among women. Therefore, informing patients better should be a priority, with particular attention on the risks and needs of women with a migration background. Specific programs for women with and without migration background should be developed to increase the awareness of osteoporosis

The Advocate - March 14, 1963

Original title (1951-1987)--The Advocate: official publication of the Archdiocese of Newark (N.J.)

Outcome of revascularization therapy in traumatized immature incisors

Background: The aim of this retrospective analysis was to evaluate the clinical and radiological outcome of revascularization therapy in traumatized permanent incisors to determine whether this approach could be implemented into clinical routine. Methods: A total of 16 traumatized incisors (either avulsion or severe luxation/intrusion) with open apices (> 1 mm) that underwent revascularization following a standardized protocol were analyzed with a mean follow-up of 22 months. Radiographs and clinical parameters (such as root length, pulp space, dentin wall width, apical foramen, alveolar bone loss, ankylosis/mobility, supra−/infraposition, discoloration, probing depth) were compared pre- and postoperatively and statistically analyzed. Results: Over the follow-up period, 81.3% of the teeth survived revascularization and regained sensitivity, while 18.7% failed, as they had to be extracted due to serious root resorption. Regarding radiographic outcomes a significant difference could only be found in the decrease of apical foramina (p = 0.04). The other parameters showed no significant difference between pre- and postoperative measurements. More than half of the teeth (56.3%) developed root resorptions and 31.3% displayed signs of ankylosis and 92.9% developed discolorations during follow-up. However, 85.7% of the teeth maintained the bone level and outcomes of mobility showed a significant solidification. Conclusions: Revascularization is a promising approach for the treatment of immature incisors to regain sensitivity and to enhance apical closure and at least to maintain alveolar bone in terms of a socket preservation. Further studies have to be performed to determine ideal conditions (type of trauma, age, width of apical foramen) for a revascularization

An investigation of control allocation methods for the ADMIRE simulation model

This paper presents a comparative study of various control allocation methods, using ADMIRE as a benchmark simulation model. The Ganged Pseudo-Inverse, Weighted Pseudo-Inverse, Cascaded Generalized-Inverse, Daisy Chain, and Linear Programming approaches are evaluated and compared against each other using open loop and closed loop analysis with Euclidean-Norm. In open-loop analysis, control allocation methods are analyzed for each approach that can produce an admissible solution and be able to attain commanded moments. Then, in closed-loop analysis, control allocation methods are compared using ADMIRE nonlinear simulation model for predefined maneuvers which are defined by multiple points in the flight envelope

Diltiazem Increases the Liver Regeneration in Rats by Inhibiting TGF-β1

Transforming growth factor beta-1 (TGF- β1) is the most important inhibitory cytokine during the hepatic regeneration process. Diltiazem is a Ltype calcium channel blocker that has inhibitory effect on TGF- β1. The aim of the present study was to determine the effect of diltiazem on hepatic regeneration. Sixty female Wistar Albino rats were used. Three groups were created; the control, low dose diltiazem and high dose diltiazem groups, each consisting of 20 rats. After partial liver resection (70% hepatectomy), saline was introduced to control group, 5 mg/kg diltiazem was introduced to low dose group and 15 mg/kg diltiazem to high dose group intraperitoneally. Ten rats in each group were sacrificed on the first postoperative day and the remaining rats on the fifth day. Liver weight, mitotic rate and the Ki-67 ratio were measured for determining hepatic regeneration. Liver regeneration rate on the fifth postoperative day was significantly higher both in the low dose and high dose diltiazem groups than the control group (Low diltiazem vs control: P<0.001; High diltiazem vs control: P<0.001). No significant difference was found between the groups regarding the number of mitoses on the first and fifth days following partial hepatectomy (P>0.05). The Ki-67 ratio on the first postoperative day was significantly higher both in the low dose and high dose diltiazem groups than the control group (Low diltiazem vs control: P<0.001; High diltiazem vs control: P<0.001). Diltiazem increases liver regeneration by inhibiting TGF-β1