5 research outputs found
PHS54 Cost-Effectiveness Of A Care Program For Hiv/Aids Patients Insured By A Health Maintenance Organization In Colombia Comparing Three Health Care Providers Nationwide
- Publication venue
- Published by Elsevier Inc.
- Publication date
- Field of study
Cost-Effectiveness Of A Care Program For Hiv/Aids Patients Insured By A Health Maintenance Organization In Colombia Comparing Three Health Care Providers Nationwide
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
The granin protein family: Markers for neuroendocrine cells and tools for the diagnosis of neuroendocrine tumors
- Author
- A Cetin
- A Herbay Von
- A Laslop
- A Ooi
- A Pagani
- A Saria
- A Schimmel
- AE Bishop
- AE Bishop
- AE Walts
- AL Lacangelo
- AL Lacangelo
- AM Giudici
- AR Moattari
- B Wiedenmann
- B Wiedenmann
- BH Fasciotto
- BH Fasciotto
- BH Federspiel
- BS Wilson
- C Bordi
- C Hagn
- C Manivel
- C Tougard
- CEM Blomjous
- D G Munoz
- D Gersell
- D Grube
- DB DeStephano
- DG Munoz
- DG Munoz
- DG Munoz
- DJ Grignon
- DM Rausch
- DR Gnepp
- DS Konecki
- DT O’Connor
- DT O’Connor
- DT O’Connor
- DT O’Connor
- DW Visscher
- E Chanat
- E Chanat
- E Galindo
- E Galindo
- E Galindo
- E Haneke
- EA Turbat-Herrera
- FU Reiffen
- G Bussolati
- G Bussolati
- G Chejfec
- G Rindi
- G Wollensak
- GH Wirnsberger
- H Lassmann
- H Lassmann
- H R Harach
- H Vaudry
- H Winkler
- H-H Gerdes
- H-J Wu
- HJ Steiner
- HJ Steiner
- HP Ottinger
- IM Varndell
- J Ishizuka
- J Marksteiner
- J MĂĽller
- JA Barbosa
- JC Hutton
- JC Hutton
- JC Hutton
- JD Erickson
- JG Azzopardi
- JH Eichhron
- JJ Lewis
- JM Conlon
- JM Lauweryns
- JM Nesland
- JW Said
- JY Song
- K Funa
- K Krisch
- K Miura
- K Sekiya
- K Tatemoto
- KL Sikri
- KW Schmid
- KW Schmid
- KW Schmid
- KW Schmid
- KW Schmid
- L Jin
- L Scopsi
- L Stefaneanu
- L Usellini
- LA Adams
- LE Eiden
- LE Eiden
- LJ Deftos
- LJ Deftos
- M Bassetti
- M Chen
- M Ehrhart
- M Inoue
- M Papotti
- M Pelagi
- M Pelagi
- M Schober
- M Totsch
- M Vyberg
- MA McNutt
- MA Perez
- MA Takiyyuddin
- MA Takiyyuddin
- ME Thompson
- MG Cozzi
- MM Silver
- MN Murphy
- MR Piehl
- MR Wick
- N Kimura
- N Seidah
- NG Seidah
- P Facer
- P Rosa
- P Rosa
- P Rosa
- P Somogyi
- PA Stagno
- Q Hamid
- QA Hamid
- R Buffa
- R Buffa
- R Fischer-Colbrie
- R Fischer-Colbrie
- R Kirchmair
- R V Lloyd
- R V Lloyd
- R Weiler
- R Weiler
- R Weiler
- RE Sobol
- RI Linnoila
- RJ Hsiao
- RV Lloyd
- RV Lloyd
- RV Lloyd
- RV Lloyd
- RV Lloyd
- RV Lloyd
- RV Lloyd
- RV Lloyd
- S Benjannet
- S Hashimoto
- S Schroeder
- S-U Gorr
- SA Hearn
- SA Tooze
- SM Jensen
- SU Gorr
- SV Nash
- SW Pimplikar
- T Oka
- T Watanabe
- T Wohlfarter
- TI Johnson
- TL Johnson
- TM Pohl
- TN Moyana
- TR Ulich
- TR Ulich
- UM Benedum
- W Hartschuh
- W Hartschuh
- W Lee
- WB Huttner
- WB Huttner
- WB Huttner
- WE Schmidt
- WJ Mooi
- WM Herbst
- WM Molenaar
- Y Cetin
- Y Dayal
- Y Hamada
- YM Hijazi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.
- Author
- Aawsaj Y
- Abad Gurumeta A
- Abad-Motos A
- Abate E
- Abatini C
- Abbadessa F
- Abbas AM
- Abbassi-Ghadi N
- Abbott D
- Abbott T
- Abbott TEF
- Abd Elazeem HAS
- Abdalla M
- Abdallah M
- Abdelaal SA
- Abdeldayem H
- Abdelkarem MM
- Abdelkarim M
- Abdelmajeed A
- Abdelrahman A
- Abdelrahman S
- Abdelsamed A
- Abdou M
- Abdulkareem A
- Abdulwahed E
- Abdur-Rahman L
- Abel MK
- Abellan M
- Abosamak NE
- Abou Chaar MK
- Abou-Khalil J
- Abouassi A
- Aboulkassem H
- Abreu da Silva A
- Abu Za'nouneh FJ
- Abu J
- Abu-Nayla I
- Abubakar A
- Abukhalaf S
- Acebes Garcia F
- Achalandabaso Boira M
- Acher A
- Acrich E
- Adamina M
- Adamina M
- Adamoli L
- Addae-Boateng E
- Ademuyiwa AO
- Aderombi A
- Adeyeye A
- Adiamah A
- Adishesh M
- Agapov M
- Agarwal A
- Aggarwal A
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agoston P
- Agrawal A
- Agresta F
- Aguado H
- Aguzzoli L
- Ahad S
- Ahmadi N
- Ahmed NR
- Ahmeidat A
- Ahn JH
- Aiken T
- Aime A
- Ajlan A
- Akalin M
- Akaydin E
- Akeel N
- Akgor U
- Akhtar MA
- Akilli H
- Akin E
- Akkour K
- Akkulak M
- Akmenkalne L
- Al Abdallah M
- Al Abdel S
- Al Awwad S
- Al Habes H
- Al Maadany FS
- Al Raddadi R
- AL Sayed M
- Al-Habib A
- Al-Habsi R
- Al-Ishaq Z
- Al-Khayal K
- Al-Masri M
- Al-Mohammad A
- Al-mukhtar A
- Al-Najjar H
- Al-omishy H
- Al-Sarireh B
- Al-Tamimi Y
- Alaa S
- AlAamer O
- Aladeojebi A
- Alakaloko F
- Alam F
- Alam N
- Alam R
- Alameer E
- Alamri A
- Alamri A
- Alanbuki A
- Alatar A
- Alawneh F
- Alazawi D
- Albertsmeier M
- Albertsmeiers M
- Albi Martin B
- Alburakan A
- Alcaide Matas F
- Alconchel F
- Aldayri Z
- Aldecoa Ansorregui I
- Alderson D
- Aldokali N
- Aleksic L
- Alemanno G
- Alexoudi V
- Alfaro-Goldaracena A
- Alfieri S
- Alga A
- Alghamdi M
- Alhalal H
- Alhamed A
- Alharthi M
- Alharthi R
- Alhassan B
- Alhassan N
- Alhefdhi A
- Ali AK
- Ali M
- Ali MF
- Ali S
- Aliyeva Z
- Aljanadi F
- Aljiffry M
- Alkadeeki GZ
- Alkarak S
- Allemand C
- Allison J
- Almalik O
- Almasri M
- Almeciga A
- Almeida A
- Almeida AC
- Almeida JI
- Almgla N
- Almond M
- Almond M
- Alnumani T
- Alobeed O
- Alomair A
- Alonso de la Fuente N
- Alonso Poza A
- Alonso-Lamberti L
- Alotaibi N
- Alqannas M
- Alresaini F
- Alriyees L
- Alsaif A
- Alsaif F
- Alsalamah R
- Alsaraireh O
- Alselaim N
- Alser O
- Alshaar M
- Alshahrani M
- Alshammari S
- Alshareea E
- Alsharif F
- Alshaygy I
- Alshryda S
- Alsobhi S
- Althobaiti W
- Altintoprak F
- Alurralde C
- Alvarez E
- Alvarez MR
- Alyami M
- Alzamanan M
- Amaral MJ
- Ameerally P
- Amira G
- Amonkar S
- Amorim E
- Ampollini L
- Amrani L
- Anania G
- Anastasi A
- Anchuelo Latorre J
- Andaleeb U
- Andaya V
- Andrade AK
- Andrade R
- Andrijasevic S
- Aneke IA
- Ang K
- Angele M
- Angelo M
- Angelou D
- Angelou K
- Annamalai S
- Annessi V
- Ansarin M
- Anthoulakis C
- Antic A
- Antic S
- Antonakis P
- Antoniades K
- Antonopoulou MI
- Anula R
- Anwar S
- Anzak A
- Aoun S
- Aprile A
- Aquila F
- Aragon Achig EJ
- Aremu I
- Aremu M
- Aresu G
- Aribi N
- Aribi S
- Arican C
- Arif T
- Arigoni M
- Arikan AE
- Arkadopoulos N
- Arkha Y
- Armao T
- Armatura G
- Arminio A
- Arnaud AP
- Arrangoiz R
- Arrowsmith L
- Artigues E
- Arulanantham A
- Asaad P
- Ascensao J
- Ashcroft J
- Ashmore C
- Ashoush F
- ASiT AS
- Askari A
- Asqalan A
- Assaf M
- Assalaarachchi H
- Asti E
- Astreidis I
- Athanasakis E
- Athanasiou A
- Athayde Nemesio R
- Atherton R
- Athwal R
- Atici DS
- Atta R
- Attia D
- Augestad KM
- Australasian T
- Avci EK
- Avlund T
- Awad S
- Ayasra F
- Ayasra F
- Ayasra Y
- Aydin C
- Ayhan A
- Ayman A
- Ayorinde J
- Aytac E
- Ayub B
- Ayubi A
- Azam M
- Azamat IF
- Azevedo C
- Azevedo J
- Azevedo J
- Azevedo P
- Azizeldine MG
- Azizi A
- Azzam AY
- Baaij J
- Babar MS
- Baca B
- Bachler T
- Bacic G
- Bacon A
- Badalamenti G
- Badellino E
- Badra R
- Baena Sanfeliu E
- Baeza Pintado N
- Bagraith K
- Baia C
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- Baiao JM
- Baietti AM
- Baig M
- Bailon M
- Bajomo O
- Baker A
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- Balabel M
- Balakrishnan A
- Balasubramaniam D
- Balasubramanian I
- Baldari L
- Baldi C
- Baldini E
- Balercia P
- Balik E
- Ballabio M
- Ballal M
- Ballouhey Q
- Baloyiannis I
- Bambina F
- Ban VS
- Bandara GBK
- Bandiera A
- Bandovas JP
- Banerjee A
- Bankhead-Kendall BK
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- Banky B
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- Baptista VH
- Barabasz M
- Barbier L
- Bardet J
- Barisic G
- Barker D
- Barlow E
- Barmasse R
- Barmayehvar B
- Barnard S
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- Barra F
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- Barrett-Brown ZM
- Barrios O
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- Bartalucci B
- Bartolini I
- Bartolucci P
- Bascarevic V
- Basendowah M
- Bashir Y
- Bass G
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- Bates H
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- Batistotti P
- Batjer HH
- Batstone M
- Batstone M
- Battista MJ
- Bauer M
- Baumber R
- Baxevanidou K
- Baxter K
- Bayazeed SA
- Bayhan Z
- Beamish A
- Beard D
- Beasley N
- Beatson K
- Becerra Garcia FC
- Bechri H
- Becker R
- Beech N
- Bekele D
- Bekheit M
- Belcher E
- Belia F
- Belkhadir ZH
- Bellacci A
- Bellanti L
- Belli A
- Bello J
- Bellora P
- Belluco C
- Beltramini GA
- Beltran de Heredia J
- Belvedere A
- Benavides Buleje JA
- Benkabbou A
- Bennetts J
- Benson O
- Benson RA
- Benson RA
- Bergamini C
- Bergeat D
- Bergonzani M
- Bernal-Sprekelsen JC
- Bernante P
- Bernardi D
- Bernasconi M
- Bernon M
- Berry R
- Berselli M
- Bertelli G
- Bertoglio P
- Bertolani E
- Bertoli G
- Bescos C
- Beswick D
- Bettoni J
- Betz CS
- Bewarder J
- Beyer K
- Beyrne C
- Bezede C
- Bhalla A
- Bhangu A
- Bhangu A
- Bhangu AA
- Bhangu AA
- Bhasin S
- Bhatti MI
- Biala M
- Bianchi MF
- Bianchini M
- Bianco F
- Bianco F
- Biasini M
- Biasoni D
- Bichoo R
- Biel JR
- Bigay K
- Bilgin IA
- Bille A
- Bin Nasser A
- Bin Traiki T
- Biondi A
- Bisagni P
- Bisset C
- Bissolotti G
- Blackwell L
- Blake D
- Blanco-Colino R
- Blanco-Colino R
- Blas Laina JL
- Blatt A
- Blazer D
- Blazquez Martin A
- Boal M
- Bobinski M
- Boccalatte L
- Bocchialini G
- Bocciolone L
- Boddaert G
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- Bradshaw L
- Bradulskis S
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- Branquinho A
- Brar A
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- Breda D
- Breen KA
- Breheret R
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- Bretherton C
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- Brian E
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- Brixton G
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- Brocklehurst M
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- Bueno Canones AD
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- de Solorzano Aurusa OFJ
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- Zourntou S
- Zouzoulas D
- Zubaidi A
- Zullo A
- Publication venue
- Br J Surg
- Publication date
- 11/11/2020
- Field of study
BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. METHODS: This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. RESULTS: Of 8784 patients (432 hospitals, 53 countries), 2303 patients (26.2 per cent) underwent preoperative testing: 1458 (16.6 per cent) had a swab test, 521 (5.9 per cent) CT only, and 324 (3.7 per cent) swab and CT. Pulmonary complications occurred in 3.9 per cent, whereas SARS-CoV-2 infection was confirmed in 2.6 per cent. After risk adjustment, having at least one negative preoperative nasopharyngeal swab test (adjusted odds ratio 0.68, 95 per cent confidence interval 0.68 to 0.98; P = 0.040) was associated with a lower rate of pulmonary complications. Swab testing was beneficial before major surgery and in areas with a high 14-day SARS-CoV-2 case notification rate, but not before minor surgery or in low-risk areas. To prevent one pulmonary complication, the number needed to swab test before major or minor surgery was 18 and 48 respectively in high-risk areas, and 73 and 387 in low-risk areas. CONCLUSION: Preoperative nasopharyngeal swab testing was beneficial before major surgery and in high SARS-CoV-2 risk areas. There was no proven benefit of swab testing before minor surgery in low-risk areas
Ezetimibe added to statin therapy after acute coronary syndromes
- Author
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- Aambakk MB
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- Zweiker R
- Ă…ngman K
- Édes I
- Ă–stberg S
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2015
- Field of study
BACKGROUND: Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but whether the addition of ezetimibe, a nonstatin drug that reduces intestinal cholesterol absorption, can reduce the rate of cardiovascular events further is not known. METHODS: We conducted a double-blind, randomized trial involving 18,144 patients who had been hospitalized for an acute coronary syndrome within the preceding 10 days and had LDL cholesterol levels of 50 to 100 mg per deciliter (1.3 to 2.6 mmol per liter) if they were receiving lipid-lowering therapy or 50 to 125 mg per deciliter (1.3 to 3.2 mmol per liter) if they were not receiving lipid-lowering therapy. The combination of simvastatin (40 mg) and ezetimibe (10 mg) (simvastatin-ezetimibe) was compared with simvastatin (40 mg) and placebo (simvastatin monotherapy). The primary end point was a composite of cardiovascular death, nonfatal myocardial infarction, unstable angina requiring rehospitalization, coronary revascularization ( 6530 days after randomization), or nonfatal stroke. The median follow-up was 6 years. RESULTS: The median time-weighted average LDL cholesterol level during the study was 53.7 mg per deciliter (1.4 mmol per liter) in the simvastatin-ezetimibe group, as compared with 69.5 mg per deciliter (1.8 mmol per liter) in the simvastatin-monotherapy group (P<0.001). The Kaplan-Meier event rate for the primary end point at 7 years was 32.7% in the simvastatin-ezetimibe group, as compared with 34.7% in the simvastatin-monotherapy group (absolute risk difference, 2.0 percentage points; hazard ratio, 0.936; 95% confidence interval, 0.89 to 0.99; P = 0.016). Rates of pre-specified muscle, gallbladder, and hepatic adverse effects and cancer were similar in the two groups. CONCLUSIONS: When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit