MARKET ANALYSIS AND POTENTIAL OF UAV SYSTEMS FOR MONITORING &CARTOGRAPHY IN ECOLOGY, AGRICULTURE & FORESTRY

This paper describes recent research into Aerial Photography, Cartography and Monitoring Capa-bilities and Technologies of UAV products currently available into the market. It reviews advancement of small electric powered unmanned air vehicle (UAV) capabilities. Specifically, topics under consideration were Aerial photography and its two uses, Cartography and Monitoring within the context of proposed exploitation of UAV for Planning, control and management in Agriculture, Forestry and Ecology. In the end a design and development of a new micro-UAV “Sparrow-S” is projected

Long-term application of fertilizers on chemical and biological properties of an Alfisol

A long term fertilizer experiment (30 years) at Bengaluru had been started during 1986 with eleven treat-ments and four replications in an Alfisol on finger millet (Elusine coracana) maize (Zea mays) cropping sequence. The results of the ongoing experiment after 27 cycles of finger millet and maize on changes in soil chemical proper-ties revealed that application of inorganics alone resulted in impaired soil fertility status (soil pH, organic carbon con-tent and available nutrients in soil were decreased) over balanced fertilizer application. There was a decline in soil reaction over the initial status and the maximum decrease was observed in 100 % NP (-1.46), 100 % N (-1.20) and other treatments. Application of 100 % NPK+FYM+lime maintained the soil pH (6.2) compared to all the other treat-ments. Organic carbon content of soil in all the treatments was higher (6.46 g kg-1) compared to the initial status; however, maximum increase in organic carbon content was registered on application of NPK+FYM. Application of 10 t ha-1 along with recommended dose of fertilizers and lime was found promising in term of sustaining crop and soil productivity

Development and in-vitro evaluation of candy based medicated lollipops: a novel system of drug delivery

Lollipops or lozenges are defined as the flavored medicated dosage forms intended to be sucked and held in the mouth or pharynx containing one or more medicaments usually in the sweetened base. Lollipops are commonly used for the purpose of local or systemic effects through the buccal mucosa. Advantages of the lollipop as dosage forms include increase in bioavailability, reduction in dose size, gastric irritation and bypass first metabolism1. Lollipop is designed to improve patient compliance, acceptability, transportation etc2The lollipops were prepared by heating and congealing method in a candy based industry with sucrose base. All the formulations prepared were subjected to various physicochemical parameters like hardness, content uniformity, friability, weight variation etc. Thickness of lollipop ranges from 12-13.2 mm. The hardness of these lollipops ranges between 10-11.5 kg/cm... Results of in-vitro release profile indicated that formulation L3, L6, and L10 were the most promising formulations as the extent of drug release from this formulation was high as compare to other formulations up to 30 mins. The in vitro release of medicated lollipop of ambroxol hcl was found in the release of drug from the lollipop depends on the type and concentration of polymer used. As per all satisfactory evaluation parameters, the batch L3 is found to be optimized batch. The stability studies showed that there was no change in the formulation after 90 days. The medicated lollipops can provide an attractive alternative formulation in the treatment of mucolytics in pediatric patients. Keywords: Amboxol HCl, Lollipops, mucolytic and mucokinetics

Effect of harvesting time and desapping on sapburn and quality in mango (Mangifera indica) cv. Langra

Sapburn is one of the most important problems in mango (Mangifera indica L.) which severely downgrade its quality and reduces its market value. In the present study, two experiments were conducted to study the effect of harvesting time on sap flow quantity; and its control through simple desapping treatment. The sap flow was recorded higher from the mango fruits (cv. Langra) harvested during morning hours. For the second experiment, mature mango fruits were harvested with 8 - 10 cm pedicel attached and treated with aqueous solutions of sodium hydroxide (1% and 2%) and potassium hydroxide (1% and 2%) by immersion method, after removing the pedicel. For control, sap was allowed to flow freely over the fruit surface. During storage of fruit at ambient condition (25±2°C) for 12 days, fruits desapped with 1% sodium hydroxide (NaOH) showed about 11-fold lower sapburn injury than control. Treatment with NaOH did not significantly affect TSS, acidity and carotenoids content in the fruit. However, it maintained significantly higher ascorbic acid, total phenolics content and antioxidant activity than control

Long non-coding RNA SNHG8 drives stress granule formation in tauopathies

Tauopathies are a heterogenous group of neurodegenerative disorders characterized by tau aggregation in the brain. In a subset of tauopathies, rare mutations in the MAPT gene, which encodes the tau protein, are sufficient to cause disease; however, the events downstream of MAPT mutations are poorly understood. Here, we investigate the role of long non-coding RNAs (lncRNAs), transcripts \u3e200 nucleotides with low/no coding potential that regulate transcription and translation, and their role in tauopathy. Using stem cell derived neurons from patients carrying a MAPT p.P301L, IVS10 + 16, or p.R406W mutation and CRISPR-corrected isogenic controls, we identified transcriptomic changes that occur as a function of the MAPT mutant allele. We identified 15 lncRNAs that were commonly differentially expressed across the three MAPT mutations. The commonly differentially expressed lncRNAs interact with RNA-binding proteins that regulate stress granule formation. Among these lncRNAs, SNHG8 was significantly reduced in a mouse model of tauopathy and in FTLD-tau, progressive supranuclear palsy, and Alzheimer\u27s disease brains. We show that SNHG8 interacts with tau and stress granule-associated RNA-binding protein TIA1. Overexpression of mutant tau in vitro is sufficient to reduce SNHG8 expression and induce stress granule formation. Rescuing SNHG8 expression leads to reduced stress granule formation and reduced TIA1 levels in immortalized cells and in MAPT mutant neurons, suggesting that dysregulation of this non-coding RNA is a causal factor driving stress granule formation via TIA1 in tauopathies

Gaps in clinical research in frontotemporal dementia : A call for diversity and disparities-focused research

Frontotemporal dementia (FTD) is one of the leading causes of dementia before age 65 and often manifests as abnormal behavior (in behavioral variant FTD) or language impairment (in primary progressive aphasia). FTD's exact clinical presentation varies by culture, language, education, social norms, and other socioeconomic factors; current research and clinical practice, however, is mainly based on studies conducted in North America and Western Europe. Changes in diagnostic criteria and procedures as well as new or adapted cognitive tests are likely needed to take into consideration global diversity. This perspective paper by two professional interest areas of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment examines how increasing global diversity impacts the clinical presentation, screening, assessment, and diagnosis of FTD and its treatment and care. It subsequently provides recommendations to address immediate needs to advance global FTD research and clinical practice

Sterically Encumbered Sb (III) Selone Complex: Synthesis, Characterization and Photophysical Study

An antimony (III) selone complex was synthesized starting from the corresponding imidazole selone IPr*Se. This newly isolated Sb (III) complex was fully characterized by NMR, FT-IR, TGA and single crystal X-ray diffraction techniques. In a solid state structure the IPr*Se depicts a rare coordination mode. The molecule is a neutral binuclear antimony (III) selone with Sb:Se ratio of 2:1. Notably the Sb-Se bond length is slightly longer than expected, due to the sterically superbulky ligand. Besides the Sb---π aryl interactions was observed in the molecular packing. The antimony (III) selone represents the first example of metal selone reported with unusual coordination mode of imidazole selone. In addition, the photophysical properties of IPr*=Se and antimony (III) selone were investigated and compared