The Role of Northeast Ohio Central Cities in the Regional Economy, 2000-2007

This report examines the four central cities in Northeast Ohio – Akron, Canton, Cleveland, and Youngstown — in the context of their metropolitan areas. A central city is the largest or most important city of a metropolitan area. A metropolitan area combines a large city with adjacent urbanized areas and peripheral areas that are closely bound to the center with strong ties to commuting, commerce, and a common labor market

The Role of Northeast Ohio Central Cities in the Regional Economy, 2000-2007

This report examines the four central cities in Northeast Ohio – Akron, Canton, Cleveland, and Youngstown — in the context of their metropolitan areas. A central city is the largest or most important city of a metropolitan area. A metropolitan area combines a large city with adjacent urbanized areas and peripheral areas that are closely bound to the center with strong ties to commuting, commerce, and a common labor market

Recurrent Modification of a Conserved Cis-Regulatory Element Underlies Fruit Fly Pigmentation Diversity

The development of morphological traits occurs through the collective action of networks of genes connected at the level of gene expression. As any node in a network may be a target of evolutionary change, the recurrent targeting of the same node would indicate that the path of evolution is biased for the relevant trait and network. Although examples of parallel evolution have implicated recurrent modification of the same gene and cis-regulatory element (CRE), little is known about the mutational and molecular paths of parallel CRE evolution. In Drosophila melanogaster fruit flies, the Bric-à-brac (Bab) transcription factors control the development of a suite of sexually dimorphic traits on the posterior abdomen. Female-specific Bab expression is regulated by the dimorphic element, a CRE that possesses direct inputs from body plan (ABD-B) and sex-determination (DSX) transcription factors. Here, we find that the recurrent evolutionary modification of this CRE underlies both intraspecific and interspecific variation in female pigmentation in the melanogaster species group. By reconstructing the sequence and regulatory activity of the ancestral Drosophila melanogaster dimorphic element, we demonstrate that a handful of mutations were sufficient to create independent CRE alleles with differing activities. Moreover, intraspecific and interspecific dimorphic element evolution proceeded with little to no alterations to the known body plan and sex-determination regulatory linkages. Collectively, our findings represent an example where the paths of evolution appear biased to a specific CRE, and drastic changes in function were accompanied by deep conservation of key regulatory linkages. © 2013 Rogers et al

Observational Constraints on the Merger History of Galaxies since z ≈ 6: Probabilistic Galaxy Pair Counts in the CANDELS Fields

Galaxy mergers are expected to have a significant role in the mass assembly of galaxies in the early Universe, but there are very few observational constraints on the merger history of galaxies at $z>2$. We present the first study of galaxy major mergers (mass ratios $>$ 1:4) in mass-selected samples out to $z\approx6$. Using all five fields of the HST/CANDELS survey and a probabilistic pair count methodology that incorporates the full photometric redshift posteriors and corrections for stellar mass completeness, we measure galaxy pair-counts for projected separations between 5 and 30 kpc in stellar mass selected samples at $9.7 < \log_{10}(\rm{M}_{*}/\rm{M}_{\odot}) < 10.3$ and $\log_{10}(\rm{M}_{*}/\rm{M}_{\odot}) > 10.3$. We find that the major merger pair fraction rises with redshift to $z\approx6$ proportional to $(1+z)^{m}$, with $m = 0.8\pm0.2$ ($m = 1.8\pm0.2$) for $\log_{10}(\rm{M}_{*} / \rm{M}_{\odot}) > 10.3$ ($9.7 < \log_{10}(\rm{M}_{*}/\rm{M}_{\odot}) < 10.3$). Investigating the pair fraction as a function of mass ratio between 1:20 and 1:1, we find no evidence for a strong evolution in the relative numbers of minor to major mergers out to $z<3$. Using evolving merger timescales we find that the merger rate per galaxy ($\mathcal{R}$) rises rapidly from $0.07\pm 0.01$ Gyr$^{-1}$ at $z < 1$ to $7.6\pm 2.7$ Gyr$^{-1}$ at $z = 6$ for galaxies at $\log_{10}(\rm{M}_{*}/\rm{M}_{\odot}) > 10.3$. The corresponding co-moving major merger rate density remains roughly constant during this time, with rates of $\Gamma \approx 10^{-4}$ Gyr$^{-1}$ Mpc$^{-3}$. Based on the observed merger rates per galaxy, we infer specific mass accretion rates from major mergers that are comparable to the specific star-formation rates for the same mass galaxies at $z>3$ - observational evidence that mergers are as important a mechanism for building up mass at high redshift as in-situ star-formation.Comment: 36 pages, 17 figures. Accepted for publication in Ap

Genomic Tools for Evolution and Conservation in the Chimpanzee: Pan troglodytes ellioti Is a Genetically Distinct Population

In spite of its evolutionary significance and conservation importance, the population structure of the common chimpanzee, Pan troglodytes, is still poorly understood. An issue of particular controversy is whether the proposed fourth subspecies of chimpanzee, Pan troglodytes ellioti, from parts of Nigeria and Cameroon, is genetically distinct. Although modern high-throughput SNP genotyping has had a major impact on our understanding of human population structure and demographic history, its application to ecological, demographic, or conservation questions in non-human species has been extremely limited. Here we apply these tools to chimpanzee population structure, using ∼700 autosomal SNPs derived from chimpanzee genomic data and a further ∼100 SNPs from targeted re-sequencing. We demonstrate conclusively the existence of P. t. ellioti as a genetically distinct subgroup. We show that there is clear differentiation between the verus, troglodytes, and ellioti populations at the SNP and haplotype level, on a scale that is greater than that separating continental human populations. Further, we show that only a small set of SNPs (10–20) is needed to successfully assign individuals to these populations. Tellingly, use of only mitochondrial DNA variation to classify individuals is erroneous in 4 of 54 cases, reinforcing the dangers of basing demographic inference on a single locus and implying that the demographic history of the species is more complicated than that suggested analyses based solely on mtDNA. In this study we demonstrate the feasibility of developing economical and robust tests of individual chimpanzee origin as well as in-depth studies of population structure. These findings have important implications for conservation strategies and our understanding of the evolution of chimpanzees. They also act as a proof-of-principle for the use of cheap high-throughput genomic methods for ecological questions

Selected physical, biological and biogeochemical implications of a rapidly changing Arctic Marginal Ice Zone

The Marginal Ice Zone (MIZ) of the Arctic Ocean is changing rapidly due to a warming Arctic climate with commensurate reductions in sea ice extent and thickness. This Pan-Arctic review summarizes the main changes in the Arctic ocean–sea ice–atmosphere (OSA) interface, with implications for primary- and secondary producers in the ice and the underlying water column. Changes in the Arctic MIZ were interpreted for the period 1979–2010, based on best-fit regressions for each month. Trends of increasingly open water were statistically significant for each month, with quadratic fit for August–November, illustrating particularly strong seasonal feedbacks in sea-ice formation and decay. Geographic interpretations of physical and biological changes were based on comparison of regions with significant changes in sea ice: (1) The Pacific Sector of the Arctic Ocean including the Canada Basin and the Beaufort, Chukchi and East Siberian seas; (2) The Canadian Arctic Archipelago; (3) Baffin Bay and Hudson Bay; and (4) the Barents and Kara seas. Changes in ice conditions in the Barents sea/Kara sea region appear to be primarily forced by ocean heat fluxes during winter, whereas changes in the other sectors appear to be more summer–autumn related and primarily atmospherically forced. Effects of seasonal and regional changes in OSA-system with regard to increased open water were summarized for photosynthetically available radiation, nutrient delivery to the euphotic zone, primary production of ice algae and phytoplankton, ice-associated fauna and zooplankton, and gas exchange of CO2. Changes in the physical factors varied amongst regions, and showed direct effects on organisms linked to sea ice. Zooplankton species appear to be more flexible and likely able to adapt to variability in the onset of primary production. The major changes identified for the ice-associated ecosystem are with regard to production timing and abundance or biomass of ice flora and fauna, which are related to regional changes in sea-ice conditions

Optics of Balloon Experimental Twin Telescope for Infrared Interferometry (BETTII): delay lines and alignment

We present the optics of Balloon Experimental Twin Telescope for Infrared Interferometry (BETTII) as it gets ready for launch. BETTII is an 8-meter baseline far-infrared (30-90 μm) interferometer mission with capabilities of spatially resolved spectroscopy aimed at studying star formation and galaxy evolution. The instrument collects light from its two arms, makes them interfere, divides them into two science channels (30-50 μm and 60-90 μm), and focuses them onto the detectors. It also separates out the NIR light (1-2.5 μm) and uses it for tip-tilt corrections of the telescope pointing. Currently, all the optical elements have been fabricated, heat treated, coated appropriately and are mounted on their respective assemblies. We are presenting the optical design challenges for such a balloon borne spatio- spectral interferometer, and discuss how they have been mitigated. The warm and cold delay lines are an important part of this optics train. The warm delay line corrects for path length differences between the left and the right arm due to balloon pendulation, while the cold delay line is aimed at introducing a systematic path length difference, thereby generating our interferograms from where we can derive information about the spectra. The details of their design and the results of the testing of these opto-mechanical parts are also discussed. The sensitivities of different optical elements on the interferograms produced have been determined with the help of simulations using FRED software package. Accordingly, an alignment plan is drawn up which makes use of a laser tracker, a CMM, theodolites and a LUPI interferometer