Melia azedarach L. Fruit Extract as a potencial candidate in controlling the Neuraeschna Hagen, 1867 (Odonata: Aeshnidae), predominant predators for fish fingerlings

Odonata larvae in fishponds prey on fish fingerlings and decrease the profits from production. With the goal of eliminating these larvae from fishponds, large quantities of pesticides are applied. These products are toxic to fish and have unpredictable effects on the food chain. The objective of this study is to evaluate the effect of the plant extract of fruits of Melia azedarach (CEE) and of methyl parathion (MP) adsorbed in silica in the control of Neuraeschna larvae (Odonata: Aeshnidae). The LC50-18h for CEE was 0.57 mg L-1, and for MP the LC50-12h was 0.17 mg L-1. Two compounds  with the highest concentration were isolated and identified from CEE, linoleic acid and melianone. The latter is a triterpene precursor of limonoids, compounds with insecticide properties. The substitution of synthetic pesticides for natural products is a path towards the sustainability of fish farming

BIO-SUSHY PFAS FREE SOLUTION WITH FOCUS ON THERMOPLASTIC BASED POWDERS FOR FOOD PACKAGING APPLICATIONS

<p>BIO-SUSHY project aims to develop 3 PFAS-free coating materials partially or fully bio-based to be validated in 3 case studies textile, food and glass packaging. In parallel with material development covering sol-gel and thermoplastic powder coatings integration of safety and sustainability into the coating formulations using multidisciplinary approach of computational tools, predictive models and data-driven simulations is covered from an early R&D phase. The highlights from the latest results on bio-based biodegradable thermoplastic formulations using spray coating on paper substrates will be briefly presented. </p&gt

Efeito do extrato de Melia azedarach sobre a predação de alevinos de carpa comum (Cyprinus carpio) por larvas de Neuraeschna (Odonata: Aeshnidae)

The presence of larvae of predator insects in fish farming ponds is one of the factors that contribute to the reduction of the survival of fingerlings and consequently to the decrease of production profits. Dragonflies, which belong to the order Odonata and lay their eggs directly in the water, are among the insects that have a harmful effect on fish farming. The larvae are starving carnivore: they predate post-larvae fish and fingerlings and thus become economically relevant plagues. The objective of this work is to study the occurrence of odonata larvae in fish ponds and evaluate the effect of vegetal extracts adsorved in silica to control odonata larvae predation on common carp. A total of 126 larvae (INSECTA: ODONATA) of the suborder Anisoptera were registered in the monitored ponds. Of those, 80 belonged to the family Aeshnidae and 46 to the Libellulidae. The genera Neuraeschna was dominant in the three sampled ponds and was used in the biological tests. During the tests of predation of fingerlings of common carps (Cyprinus carpio) by the Neuraeschna larva, the daily consumption was of 5,2 and 7,2 fingerlings in the treatments with and without EEC, respectively.). The adoption of Good Practises in Aquaculture and the sustainability of fish farming request the adoption of natural products

Highly purified eicosapentaenoic acid as free fatty acids strongly suppresses polyps in Apc(Min/+) mice.

Although cyclooxygenase (COX)-2 inhibitors could represent the most effective chemopreventive tool against colorectal cancer (CRC), their use in clinical practice is hampered by cardiovascular side effects. Consumption of \u3c9-3-polyunsaturated fatty acids (\u3c9-3-PUFAs) is associated with a reduced risk of CRC. Therefore, in this study, we assessed the efficacy of a novel 99% pure preparation of \u3c9-3-PUFA eicosapentaenoic acid as free fatty acids (EPA-FFA) on polyps in Apc(Min/+) mice. Experimental design: Apc(Min/+) and corresponding wild-type mice were fed control diet (Ctrl) or diets containing either EPA-FFA 2.5% or 5%, for 12 weeks while monitoring food intake and body weight. RESULTS: We found that both EPA-FFA diets protected from the cachexia observed among Apc(Min/+) animals fed Ctrl diet (P < 0.0054), without toxic effect, in conjunction with a significant decrease in lipid peroxidation in the treated arms. Moreover, both EPA-FFA diets dramatically suppressed polyp number (by 71.5% and 78.6%, respectively; P < 0.0001) and load (by 82.5% and 93.4%, respectively; P < 0.0001) in both small intestine and colon. In addition, polyps less than 1 mm in size were predominantly found in the EPA-FFA 5% arm whereas those 1 to 3 mm in size were more frequent in the Ctrl arm (P < 0.0001). Interestingly, in the EPA-FFA groups, mucosal arachidonic acid was replaced by EPA (P < 0.0001), leading to a significant reduction in COX-2 expression and \u3b2-catenin nuclear translocation. Moreover, in the EPA-FFA arms, we found a significant decrease in proliferation throughout the intestine together with an increase in apoptosis. CONCLUSIONS: Our data make 99% pure EPA-FFA an excellent candidate for CRC chemoprevention