136 research outputs found

    Indonesian first national suicide prevention strategy: key findings from the qualitative situational analysis

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    The reduction of suicide is a priority within the United Nations’ Sustainable Development Goals. However, Indonesia—the fourth most populous country globally—does not have a national suicide prevention strategy. Thus, in 2021, we began developing such a strategy, starting with a situational analysis recommended by the WHO LIVE-LIFE framework.1 This nationwide effort was led by a leadership committee advised by the Ministry of Health and WHO Indonesia

    The 4D nucleome project

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    Addressing risk factors for child abuse among high risk pregnant women: design of a randomised controlled trial of the nurse family partnership in Dutch preventive health care

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    <p>Abstract</p> <p>Background</p> <p>Low socio-economic status combined with other risk factors affects a person's physical and psychosocial health from childhood to adulthood. The societal impact of these problems is huge, and the consequences carry on into the next generation(s). Although several studies show these consequences, only a few actually intervene on these issues. In the United States, the Nurse Family Partnership focuses on high risk pregnant women and their children. The main goal of this program is primary prevention of child abuse. The Netherlands is the first country outside the United States allowed to translate and culturally adapt the Nurse Family Partnership into VoorZorg. The aim of the present study is to assess whether VoorZorg is as effective in the Netherland as in the United States.</p> <p>Methods</p> <p>The study consists of three partly overlapping phases. Phase 1 was the translation and cultural adaptation of Nurse Family Partnership and the design of a two-stage selection procedure. Phase 2 was a pilot study to examine the conditions for implementation. Phase 3 is the randomized controlled trial of VoorZorg compared to the care as usual. Primary outcome measures were smoking cessation during pregnancy and after birth, birth outcomes, child development, child abuse and domestic violence. The secondary outcome measure was the number of risk factors present.</p> <p>Discussion</p> <p>This study shows that the Nurse Family Partnership was successfully translated and culturally adapted into the Dutch health care system and that this program fulfills the needs of high-risk pregnant women. We hypothesize that this program will be effective in addressing risk factors that operate during pregnancy and childhood and compromise fetal and child development.</p> <p>Trial registration</p> <p>Current Controlled Trials <a href="http://www.controlled-trials.com/ISRCTN16131117">ISRCTN16131117</a></p

    The SAGE-Spec Spitzer Legacy Program: The Life Cycle of Dust and Gas in the Large Magellanic Cloud

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    The SAGE-Spec Spitzer Legacy program is a spectroscopic follow-up to the SAGE-LMC photometric survey of the Large Magellanic Cloud carried out with the Spitzer Space Telescope. We present an overview of SAGE-Spec and some of its first results. The SAGE-Spec program aims to study the life cycle of gas and dust in the Large Magellanic Cloud and to provide information essential to the classification of the point sources observed in the earlier SAGE-LMC photometric survey. We acquired 224.6 h of observations using the infrared spectrograph and the spectral energy distribution (SED) mode of the Multiband Imaging Photometer for Spitzer. The SAGE-Spec data, along with archival Spitzer spectroscopy of objects in the Large Magellanic Cloud, are reduced and delivered to the community. We discuss the observing strategy, the specific data-reduction pipelines applied, and the dissemination of data products to the scientific community. Initial science results include the first detection of an extragalactic 21 ÎŒm feature toward an evolved star and elucidation of the nature of disks around RV Tauri stars in the Large Magellanic Cloud. Toward some young stars, ice features are observed in absorption. We also serendipitously observed a background quasar, at a redshift of z ≈ 0.14, which appears to be hostless

    Causal mechanisms proposed for the Alcohol Harm Paradox - a systematic review

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    Background and Aims The Alcohol Harm Paradox (AHP) posits that disadvantaged groups suffer from higher rates of alcohol-related harm compared with advantaged groups, despite reporting similar or lower levels of consumption on average. The causes of this relationship remain unclear. This study aimed to identify explanations proposed for the AHP. Secondary aims were to review the existing evidence for those explanations and investigate whether authors linked explanations to one another. Methods Systematic review. We searched MEDLINE (1946-January 2021), EMBASE (1974 – January 2021) and PsycINFO (1967 – January 2021), supplemented via manual searching of grey literature. Included papers either explored the causes of the AHP or investigated the relationship between alcohol consumption, alcohol-related harm, and socioeconomic position. Papers were set in Organisation for Economic Co-operation and Development high income countries. Explanations extracted for analysis could be evidenced in the empirical results or suggested by researchers in their narrative. Inductive thematic analysis was applied to group explanations. Results Seventy-nine papers met the inclusion criteria and initial coding revealed these papers contained 41 distinct explanations for the AHP. Following inductive thematic analysis, these explanations were grouped into 16 themes within six broad domains: Individual, Lifestyle, Contextual, Disadvantage, Upstream and Artefactual. Explanations related to risk behaviours, which fit within the Lifestyle domain, were the most frequently proposed (n=51) and analysed (n=21). Conclusions While there are many potential explanations for the Alcohol Harm Paradox, most research focuses on risk behaviours while other explanations lack empirical testing

    Racism as a determinant of health: a systematic review and meta-analysis

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    Despite a growing body of epidemiological evidence in recent years documenting the health impacts of racism, the cumulative evidence base has yet to be synthesized in a comprehensive meta-analysis focused specifically on racism as a determinant of health. This meta-analysis reviewed the literature focusing on the relationship between reported racism and mental and physical health outcomes. Data from 293 studies reported in 333 articles published between 1983 and 2013, and conducted predominately in the U.S., were analysed using random effects models and mean weighted effect sizes. Racism was associated with poorer mental health (negative mental health: r = -.23, 95% CI [-.24,-.21], k = 227; positive mental health: r = -.13, 95% CI [-.16,-.10], k = 113), including depression, anxiety, psychological stress and various other outcomes. Racism was also associated with poorer general health (r = -.13 (95% CI [-.18,-.09], k = 30), and poorer physical health (r = -.09, 95% CI [-.12,-.06], k = 50). Moderation effects were found for some outcomes with regard to study and exposure characteristics. Effect sizes of racism on mental health were stronger in cross-sectional compared with longitudinal data and in non-representative samples compared with representative samples. Age, sex, birthplace and education level did not moderate the effects of racism on health. Ethnicity significantly moderated the effect of racism on negative mental health and physical health: the association between racism and negative mental health was significantly stronger for Asian American and Latino(a) American participants compared with African American participants, and the association between racism and physical health was significantly stronger for Latino(a) American participants compared with African American participants.<br /
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