2,243 research outputs found
Investigation into Travel Modes for Transit Oriented Development: Employees' Travel Survey of Kelvin Grove Urban Village
Travel surveys were conducted for collecting data related to visitors travel to Kelvin Grove Urban Village (KGUV). KGUV has employees of retail shopping centre, employees of educational land use, school and university students and shoppers as visitors of this area. As a part of data collection process a travel surveys was undertaken for employees and students of KGUV. This document contains the questionnaire form used to collect the data related to employee travel. Similar questions were asked to the students of KGUV. The instructions given for filling out the survey were not included in the actual questionnaire form as internet based surveys were undertaken. This form was used for personal interviews and Computer Assisted Personal Interview (CAPI) surveys undertaken for employees of the retail shopping centre
Seguridad del paciente en el bloque quirúrgico. Una perspectiva enfermera
Las consecuencias sanitarias, sociales y económicas de los efectos adversos que se producen en el contexto de la prestación sanitaria, han llevado a diferentes organismos internacionales, en los últimos años, a reflexionar sobre la seguridad del paciente y sobre la gestión de riesgos sanitarios, a desarrollar recomendaciones y estrategias orientadas a la prevención, detección y mitigación de los sucesos adversos, así como al análisis de sus causas, al aprendizaje de los errores y a la difusión de las lecciones aprendidas. El presente trabajo titulado “La seguridad del paciente en el bloque quirúrgico. Una perspectiva enfermera”, pretende describir aquellos requisitos o recomendaciones funcionales, estructurales y organizativos del Bloque Quirúrgico que garantizan las condiciones adecuadas de calidad y seguridad para realizar la intervención quirúrgica ; y por otra parte, analizar las intervenciones de enfermería encaminadas a garantizar la seguridad del paciente durante el proceso quirúrgico y que son fundamentales para contribuir a la disminución de los efectos adversos relacionados con el mismo
Hepatoprotective Effect of Cassia Fistula Linn.
A number of herbal preparations are used throughout the world for the management of the hepatic disorders. However, many of them have not been investigated for their described effects. Cassia fistula Linn. is one such drug used in the treatment of hepatitis in folk medicine. Therefore, an attempt was made to investigate the hepatoprotective effect of leaves and bark of Cassia fistula against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. Sixty albino Wistar rats were divided into six equal groups of 10. Four groups received extracts leaves/bark of Cassia fistula and intraperitoneal (i.p.) CCl4 (0.2 ml/100 g) either before or after administration of extracts. Two groups were controls, one treated with CCl4 and one with normal saline. Liver damage was assessed by plasma concentration of bilirubin and enzyme activities of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase. Treatment with aqueous extract of leaves and bark significantly reduced CCl4 -induced elevation in plasma enzyme and bilirubin concentration in rats. This study demonstrated that CCl4 -induced liver damage in rats can be ameliorated by treatment of extracts from leaves and bark
Acute toxicity of metasystox to wedge clam, Donax cuneatus from west coast
96h acute toxicity tests were performed using commercial grade metasystox on the marine wedge clam, Donax cuneatus during summer 1985. The behaviour and mortality rates were recorded periodically. Most of the dams responded in opening the shell valves and extending the siphons quicker in low test concentrations (0.004-0.0052 p.p.m) but this was slow and late in high concentrations (0.0056-0.008 p.p.m). Mortality began to occur in 0.008 p.p.m. from 12 h, whereas, in 0.0052 p.p.m. from 60 h onwards. The observed LC sub(0) value was 0.004 p.p.m. and LC sub(50) 0.0064 p.p.m. The regression equation established was Y = 79.0891 + 33.4523 X. The rate of oxygen concentration increased at LC sub(0) and LC sub(50) values compared to control indicating the disturbed physiological adjustment. The results are correlated with physico-chemical parameters of seawater and discussed in the light of pesticide toxicity to the dam
Generalization of GLRT-Based Magnetic Anomaly Detection
International audienceMagnetic anomaly detection (MAD) refers to a passive method used to reveal hidden magnetic masses and is most commonly based on a dipolar target model. This paper proposes a generalization of the MAD through a multipolar model that provides a more precise description of the anomaly and serves a twofold objective: to improve the detection performance , and to widen the variety of detectable targets. The dipole detection strategy – namely an orthonormal decomposition of the anomaly followed by a generalized likelihood ratio test – is hence revisited in the multipolar case. The performance are assessed analytically and the relevance of this generalization is demonstrated on multipolar scenarios
Differential diagnostic value of CD5 and CD117 expression in thoracic tumors: A large scale study of 1465 non-small cell lung cancer cases
Background: Thoracic pathologists are frequently faced with tissue specimens from intrathoracic/mediastinal tumors. Specifically the differentiation between thymic and pulmonary squamous cell carcinomas (SqCC) can be challenging. In order to clarify the differential diagnostic value of CD5 and CD117 in this setting, we performed a large scale expression study of both markers in 1465 non-small cell lung cancer (NSCLC) cases. Methods: Tissue microarrays of formalin-fixed paraffin-embedded resection specimens of 1465 NSCLC were stained with antibodies against CD117 and CD5. Positivity of both markers was correlated with clinicopathological variables. Results: CD117 was positive in 145 out of 1457 evaluable cases (9.9 %) and CD5 was positive in 133 out of 1427 evaluable cases (9.3 %). 28 cases (1.9 %) showed coexpression of CD117 and CD5. Among the 145 cases that were positive for CD117, 97 (66.8 %) were adenocarcinomas (ADC), 34 (23.4 %) were SqCC, 5 (3.4 %) were adenosquamous carcinomas (ADSqCC), 8 (5.5 %) were large cell carcinomas (LC), and one (0.6 %) was a pleomorphic carcinoma (PC). In the CD5 positive group consisting of 133 cases, 123 (92.4 %) were ADC, 0 (0 %) were SqCC, 4 (3.0 %) were ADSqCC, 3 (2.2 %) LC and 3 (2.2 %) were PC. None of the 586 SqCC showed expression of CD5. No association of CD117- or CD5 positivity to patients’ age, pathological stages or to T-, N-, or M- categories was observed. Conclusions: A substantial subset of NSCLC exhibit positivity of CD117 and CD5. Since CD5 expression was not observed in pulmonary SqCC, but is expressed in the majority of thymic squamous cell carcinomas, the application of this immunomarker is a valuable tool in the differential diagnosis of thoracic neoplasms
Blood-sampling collection prior to surgery may have a significant influence upon biomarker concentrations measured
Abstract Background Biomarkers can be subtle tools to aid the diagnosis, prognosis and monitoring of therapy and disease progression. The validation of biomarkers is a cumbersome process involving many steps. Serum samples from lung cancer patients were collected in the framework of a larger study for evaluation of biomarkers for early detection of lung cancer. The analysis of biomarker levels measured revealed a noticeable difference in certain biomarker values that exhibited a dependence of the time point and setting of the sampling. Biomarker concentrations differed significantly if taken before or after the induction of anesthesia and if sampled via venipuncture or arterial catheter. Methods To investigate this observation, blood samples from 13 patients were drawn 1–2 days prior to surgery (T1), on the same day by venipuncture (T2) and after induction of anesthesia via arterial catheter (T3). The biomarkers Squamous Cell Carcinoma antigen (CanAG SCC EIA, Fujirebio Diagnostics, Malvern, USA), Carcinoembrionic Antigen (CEA), and CYFRA 21-1 (Roche Diagnostics GmbH, Mannheim, Germany) were analyzed. Results SCC showed a very strong effect in relation to the sampling time and procedure. While the first two points in time (T1; T2) were highly comparable (median fold-change: 0.84; p = 0.7354; correlation ρ = 0.883), patients showed a significant increase (median fold-change: 4.96; p = 0.0017; correlation ρ = -0.036) in concentration when comparing T1 with the sample time subsequent to anesthesia induction (T3). A much weaker increase was found for CYFRA 21-1 at T3 (median fold-change: 1.40; p = 0.0479). The concentration of CEA showed a very small, but systematic decrease (median fold-change: 0.72; p = 0.0039). Conclusions In this study we show the unexpectedly marked influence of blood withdrawal timing (before vs. after anesthesia) and procedure (venous versus arterial vessel puncture) has on the concentration of the protein biomarker SCC and to a less extent upon CYFRA21-1. The potential causes for these effects remain to be elucidated in subsequent studies, however these findings highlight the importance of a standardized, controlled blood collection protocol for biomarker detection
Synthesis and characterization of a new chemically bonded liquid crystal stationary phase for HPLC
Omega-3 Fatty Acids Supplementation in Children to Prevent Asthma: Is It Worthy?—A Systematic Review and Meta-Analysis
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