151 research outputs found

    Manner of Growth of Listeria Using the Flagella as Markers

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    Comparison of Pressurized and Gravity Distribution Systems for Wastewater Treatment

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    Pressurized distribution of domestic wastewater over a sand filter surface achieves better treatment than gravity distribution. The pressurized distribution system caused the filter to better remove organics (BOD₅) and suspended solids. Pressurized distribution also caused the sand filter to achieve more complete nitrification than the filter having gravity distribution. Two slow sand filters 15.2 cm wide, 3.1 m long and 15.2 cm deep were built and loaded with domestic septic tank effluent for 250 days at a rate of 5.1 cm per day. Influent and effluent samples were collected and analyzed for five-day Biochemical Oxygen Demand (BOD₅), suspended solids, ammonia- nitrogen, and nitrate-nitrogen. One filter received septic tank effluent through a 10 cm nominal diameter PVC perforated pipe viaa distribution box dosed by a pump with gravity flow from the distribution box to the pipe. The other filter received water through a 2.5 cm nominal diameter PVC pipe having 0.4 cm diameter holes drilled 76.2 cm on center. The gravity distribution filter system achieved mean effluent values of 36.4 mg// BOD₅ , 19.8 mg// suspended solids, 37.6 mg// ammonia-nitrogen, and 46.6 mg// nitrate-nitrogen. The pressurized distribution system achieved 19.1 mg// BOD₅\u3e 12.2 mg// suspended solids, 25.3 mg// ammonia-nitrogen, and 64.03 mg// nitrate-nitrogen. Influent to the filters averaged 132.1 mg// , 90.3 mg//, 70.3 mg// , and 3.6 mg// BOD₅ , suspended solids, ammonia-nitrogen, and nitrate- nitrogen, respectively

    Reconfigurable antenna pattern verification

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    A method of verifying programmable antenna configurations is disclosed. The method comprises selecting a desired antenna configuration from a plurality of antenna configuration patterns, with the selected antenna configuration forming at least one reconfigurable antenna from reconfigurable antenna array elements. The method validates the formation of the selected antenna configuration to determine antenna performance of the at least one reconfigurable antenna

    Antenna reconfiguration verification and validation

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    A method of testing the electrical functionality of an optically controlled switch in a reconfigurable antenna is provided. The method includes configuring one or more conductive paths between one or more feed points and one or more test point with switches in the reconfigurable antenna. Applying one or more test signals to the one or more feed points. Monitoring the one or more test points in response to the one or more test signals and determining the functionality of the switch based upon the monitoring of the one or more test points

    Application of a single-objective, hybrid genetic algorithm approach to pharmacokinetic model building.

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    A limitation in traditional stepwise population pharmacokinetic model building is the difficulty in handling interactions between model components. To address this issue, a method was previously introduced which couples NONMEM parameter estimation and model fitness evaluation to a single-objective, hybrid genetic algorithm for global optimization of the model structure. In this study, the generalizability of this approach for pharmacokinetic model building is evaluated by comparing (1) correct and spurious covariate relationships in a simulated dataset resulting from automated stepwise covariate modeling, Lasso methods, and single-objective hybrid genetic algorithm approaches to covariate identification and (2) information criteria values, model structures, convergence, and model parameter values resulting from manual stepwise versus single-objective, hybrid genetic algorithm approaches to model building for seven compounds. Both manual stepwise and single-objective, hybrid genetic algorithm approaches to model building were applied, blinded to the results of the other approach, for selection of the compartment structure as well as inclusion and model form of inter-individual and inter-occasion variability, residual error, and covariates from a common set of model options. For the simulated dataset, stepwise covariate modeling identified three of four true covariates and two spurious covariates; Lasso identified two of four true and 0 spurious covariates; and the single-objective, hybrid genetic algorithm identified three of four true covariates and one spurious covariate. For the clinical datasets, the Akaike information criterion was a median of 22.3 points lower (range of 470.5 point decrease to 0.1 point decrease) for the best single-objective hybrid genetic-algorithm candidate model versus the final manual stepwise model: the Akaike information criterion was lower by greater than 10 points for four compounds and differed by less than 10 points for three compounds. The root mean squared error and absolute mean prediction error of the best single-objective hybrid genetic algorithm candidates were a median of 0.2 points higher (range of 38.9 point decrease to 27.3 point increase) and 0.02 points lower (range of 0.98 point decrease to 0.74 point increase), respectively, than that of the final stepwise models. In addition, the best single-objective, hybrid genetic algorithm candidate models had successful convergence and covariance steps for each compound, used the same compartment structure as the manual stepwise approach for 6 of 7 (86 %) compounds, and identified 54 % (7 of 13) of covariates included by the manual stepwise approach and 16 covariate relationships not included by manual stepwise models. The model parameter values between the final manual stepwise and best single-objective, hybrid genetic algorithm models differed by a median of 26.7 % (q₁ = 4.9 % and q₃ = 57.1 %). Finally, the single-objective, hybrid genetic algorithm approach was able to identify models capable of estimating absorption rate parameters for four compounds that the manual stepwise approach did not identify. The single-objective, hybrid genetic algorithm represents a general pharmacokinetic model building methodology whose ability to rapidly search the feasible solution space leads to nearly equivalent or superior model fits to pharmacokinetic data

    Psychological Barriers to a Peaceful Resolution: Longitudinal Evidence from the Middle East and Northern Ireland

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    Does individual-level exposure to political violence prompt conciliatory attitudes? Does the answer vary by phase of conflict? The study uses longitudinal primary datasets to test the hypothesis that conflict-related experiences impact conciliation. Data were collected from Israeli Jews, Palestinians, and Protestants and Catholics in Northern Ireland. Across both contexts, and among both parties to each conflict, psychological distress and threat perceptions had a polarizing effect on conciliatory preferences. The study highlights that experiences of political violence are potentially a crucial source of psychological distress, and consequently, a continuing barrier to peace. This has implications in peacemaking, implying that alongside removing the real threat of violence, peacemakers must also work toward the social and political inclusion of those most affected by previous violence
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