The Role of Fiscal Policy in Human Development: The Pakistan’s Perspective

Human development considered as the engine of the economic growth as it improves the economy’s strength and increases the standard of living of the people, increases the choices and maximises the welfare of the society that is the prime objective of any government. The development of the human capabilities is also necessary for the sustainable growth, as there are many channels through which human development foster the economic growth. It increases the labour productivity, labour demand, employment and output. On the other hand, human capital also attracts physical capital.1 Empirically, it is very difficult to have an exact measure of human development and social welfare. Several proxies used to measure human development, e.g. GNI per capita as a measure of standard of living, Purchasing Power Parity (PPP) criterion to measure the cost of living and to measure the welfare, average year of schooling, school enrolment rate and health expenditures as a percentage of GDP to capture this composite welfare and development indicator. A fair index of Human Development Index (HDI) was developed by United Nations Development Programme in 1990. This index based on the standard of living (natural logarithm of GDP PPP per capita), access to knowledge (adult literacy rate with two-third weighting and the remaining is the gross enrolment ratio) and a healthy life (life expectancy at birth). The value of index varies from 0 to 1, lower the HDI, lesser would be the human development and welfare in the country or vice versa

To study the procurement process and develop a conceptual framework model in the Pakistani construction industry

Procurement of equipment and materials in any construction project holds a tremendous significance for the project to be completed on time and within the budget. In this research, procurement in the Pakistan’s construction industry has been studied and a conceptual framework in terms of e-procurement portal has been suggested to smoothly execute the process of e-procurement by mitigating the barriers involved in the concerned process. A questionnaire survey form has been developed and 100 responses have been recorded to take the input from industry experts on the proposed procurement framework. A total of 84 respondents out of 100 thought that the proposed framework will be a better way to solve the problems that come up during the procurement process. Furthermore, it was also found that the main reason for procurement delays in construction projects is lack of communication and coordination among different departments within an organization, to which the suggested framework can be used as a potential tool to deal with

Potent Implications of miRNA in Cancer Biology – A Brief Review

Groundbreaking findings through high-throughput technologies have deepened our understanding on an intricate interplay between products of coding sequences and noncoding RNAs. Increasingly it is being realized that miRNA, produced from what was previously considered as "genomic trash" have revolutionized the field of molecular and translational oncology. Overwhelmingly accumulating in-vitro and in-vivo studies have demonstrated that miRNA are key players involved in post-transcriptional regulation of gene network in numerous human pathologies including cancer. In this review we have attempted to provide recent advancements related to multifaceted roles played by miRNA in modulation of oncogenes and tumor suppressor genes

A Comprehensive Review of Vehicle Detection Techniques Under Varying Moving Cast Shadow Conditions Using Computer Vision and Deep Learning

Design of a vision-based traffic analytic system for urban traffic video scenes has a great potential in context of Intelligent Transportation System (ITS). It offers useful traffic-related insights at much lower costs compared to their conventional sensor based counterparts. However, it remains a challenging problem till today due to the complexity factors such as camera hardware constraints, camera movement, object occlusion, object speed, object resolution, traffic flow density, and lighting conditions etc. ITS has many applications including and not just limited to queue estimation, speed detection and different anomalies detection etc. All of these applications are primarily dependent on sensing vehicle presence to form some basis for analysis. Moving cast shadows of vehicles is one of the major problems that affects the vehicle detection as it can cause detection and tracking inaccuracies. Therefore, it is exceedingly important to distinguish dynamic objects from their moving cast shadows for accurate vehicle detection and recognition. This paper provides an in-depth comparative analysis of different traffic paradigm-focused conventional and state-of-the-art shadow detection and removal algorithms. Till date, there has been only one survey which highlights the shadow removal methodologies particularly for traffic paradigm. In this paper, a total of 70 research papers containing results of urban traffic scenes have been shortlisted from the last three decades to give a comprehensive overview of the work done in this area. The study reveals that the preferable way to make a comparative evaluation is to use the existing Highway I, II, and III datasets which are frequently used for qualitative or quantitative analysis of shadow detection or removal algorithms. Furthermore, the paper not only provides cues to solve moving cast shadow problems, but also suggests that even after the advent of Convolutional Neural Networks (CNN)-based vehicle detection methods, the problems caused by moving cast shadows persists. Therefore, this paper proposes a hybrid approach which uses a combination of conventional and state-of-the-art techniques as a pre-processing step for shadow detection and removal before using CNN for vehicles detection. The results indicate a significant improvement in vehicle detection accuracies after using the proposed approach

Sustainable banking regulations pre and during coronavirus outbreak: the moderating role of financial stability

With the worldwide dispersion of COVID-19, banking sector, among others, needs to adapt to unexpected challenges. For this purpose, this study examines the impact of sustainable banking regulations on bank-specific characteristics pre and during COVID19 period in Pakistan for the period spanning from 2006 to 2020. Moreover, financial stability is employed to test its moderating role on sustainable banking regulations. The dynamic estimator, named the system-Generalized Method of Moments, is used to analyze the endogenous nature of the data. Findings suggest that capital adequacy ratio, deposit ratio, and loan ratio are positive whereas leverage ratios are negatively related to profitability and market return. Overall, findings reveal that sustainable banking regulations influenced the bank-specific characteristics substantially. Importantly, the year-wise averages of variables reveal that Pakistani banks have made significant improvements in profitability, market return, capital adequacy, and deposit ratio pre and during pandemic era. Additionally, the financial stability significantly moderates the relationship highlighting lower default risk and the effectiveness of sustainable banking operations. Practically, despite global lockdowns, economic and trade restrictions during COVID-19, State Bank of Pakistan, sustained health of banking sector through its well-regulated monitoring mechanism

Influence of different formulation variables on the performance of transdermal drug delivery system containing tizanidine hydrochloride: in vitro and ex vivo evaluations

The present study was aimed at preparation of transdermal patches of tizanidine HCl, evaluation of the effect of polymers on in vitro release pattern of the drug, and the effect of permeation enhancers on the penetration of the drug through the rabbit skin. Various proportions of hydrophilic (HPMC) and hydrophobic (Eudragit L-100) polymers were used with PEG 400 as film-forming agent, and Span 20 or DMSO as permeation enhancer. The formulations were assessed for physicochemical characteristics and in vitro drug release studies using USP paddle over disc method in phosphate buffered saline (pH 7.4) at 32.0±1°C. On the basis of in vitro studies and physicochemical evaluations, S03-A and S04-A were selected at Eudragit : HPMC ratios of 8 : 2 and 7 : 3, respectively, for further ex vivo analysis. The effects of different concentrations of Span 20 and DMSO were evaluated on excised rabbit skin using Franz diffusion cell. Cumulative drug permeation, flux, permeability coefficient, target flux, and enhancement ratio were calculated and compared with the control formulations. Kinetic models and Tukey’s multiple comparison test were applied to evaluate the drug release patterns. Formulation SB03- PE containing Eudragit L-100:HPMC (7:3) with Span 20 (15% w/w) produced the highest enhancement in drug permeation, and followed zero order kinetic model with super case-II drug release mechanism

Enhancing Knowledge and Bounce Rate in SERPs Using Micro-Data

Internet has revolutionized the human life. SEs (Search Engines) are one of the major tools being used for finding information over the Internet. SEs enlist the information into links as per relevance to the searched query. A searcher usually visits the top web links retrieved on SERPs (Search Engine Results Pages) in response to a search query. With the evolving nature of Internet and the increasing number of competitors; it is hard to maintain high ranking in SERPs even for professional correspondents. However, correspondents can apply the techniques of web micro-data to achieve high CTR (Click through Rate) in SERPs. Ranking in major SEs is still a critical factor, although in certain cases such as movies, books, recipes rich snippets proved profitable for webmasters. This study aims to address the gap in micro-data moving from top category such as Animals to their limited scope. Animals with information such as name, price, category will have high CTR and hence more user satisfaction for specified result will lead to high ranking in SERPs

Biostimulants Application: An Innovative Approach to Food Security under Drought Stress

Climate change is a global threat to food security as it causes various biotic and abiotic stresses that adversely disturb agriculture production. With an increase in the worldwide population, the demand for food has also arisen. It is an immediate challenge for the scientific community to introduce an innovative tool to achieve food security with quality plant production and develop tolerance against abiotic stresses, specifically drought. Genetically modifications are effective and time-consuming, while biostimulants are in/organic substances with the potential to support plant development under stress conditions. This chapter focuses on the impacts of climate change on agriculture, challenges for agriculture sustainability and food security, the interrelationship between drought, climate change and food security, the potential role of biostimulants against drought, future aspects and challenges due to climate change specifically drought, and food security challenges. Various studies reported that the application of biostimulants results in enhancement of crop productivity and mitigates the harmful effects due to climate change. To ensure the quality of chapter, we collected references from well-reputed international journals using keywords ““biostimulants,” “drought,” “food security,” “agriculture sustainability,” and “climate change.” In conclusion, biostimulants has a potential to address adverse environmental conditions without affecting crop quality and yield loss

Past trends and future research suggestions

Bhutta, U., Martins, J. N., Mata, M. N., Raza, A., Dantas, R. M., Correia, A. B., & Rafiq, M. (2021). Intellectual structure and evolution of accounting conservatism research: Past trends and future research suggestions. International Journal of Financial Studies, 9(3), 1-23. [35]. https://doi.org/10.3390/ijfs9030035Accounting conservatism (AC) is one of the components of financial reporting, and has been widely studied by academicians to identify its impact on information quality. Scholars in accounting have started to explore how AC is related to different fundamental functional areas of organizations. The interest of the scholars has resulted in an increasing number of publications in this field. In this study, we examined 408 indexed publications related to AC. This work’s objectives include analyzing the regional distribution, size, and evolution of this knowledge base by identifying key authors, documents, and journals while exploring current literature, scholarly structure, and highlighting contemporary trends. The findings of the study concluded that most of the studies are conducted in developed nations contexts. However, there are still areas that need further exploration to obtain more profound insights on the subject. This bibliometric review inspires a new generation of researchers on the topic by giving them an overview of the past studies related to AC.publishersversionpublishe