Bio-bibliometric Study of Dr. Khalid Mahmood’s Contributions to LIS Field in Pakistan

This paper presents bio-bibliometric analysis of the contributions of Dr. Khalid Mahmood in the field of Library and Information Science through his publications. The analysis includes geographical and year wise distribution of publications; collaboration for publication; publications by type; language and journal preferences for the publication; and coverage of different subject areas. Results of the study indicate that Dr. Khalid Mahmood is a prolific writer in the field of library and information science. He contributed 115 items including 99 articles, six books, eight conference papers and two papers in newsletters till December 31, 2011. Research work by Dr. Khalid Mahmood is well accepted in developed countries like United Kingdom and United States of America. He used English language to disseminate majority of his research work. He believes in teamwork and about two third of his research work was result of collaboratio

Towards PACE-CAD Systems

Despite phenomenal advancements in the availability of medical image datasets and the development of modern classification algorithms, Computer-Aided Diagnosis (CAD) has had limited practical exposure in the real-world clinical workflow. This is primarily because of the inherently demanding and sensitive nature of medical diagnosis that can have far-reaching and serious repercussions in case of misdiagnosis. In this work, a paradigm called PACE (Pragmatic, Accurate, Confident, & Explainable) is presented as a set of some of must-have features for any CAD. Diagnosis of glaucoma using Retinal Fundus Images (RFIs) is taken as the primary use case for development of various methods that may enrich an ordinary CAD system with PACE. However, depending on specific requirements for different methods, other application areas in ophthalmology and dermatology have also been explored. Pragmatic CAD systems refer to a solution that can perform reliably in day-to-day clinical setup. In this research two, of possibly many, aspects of a pragmatic CAD are addressed. Firstly, observing that the existing medical image datasets are small and not representative of images taken in the real-world, a large RFI dataset for glaucoma detection is curated and published. Secondly, realising that a salient attribute of a reliable and pragmatic CAD is its ability to perform in a range of clinically relevant scenarios, classification of 622 unique cutaneous diseases in one of the largest publicly available datasets of skin lesions is successfully performed. Accuracy is one of the most essential metrics of any CAD system's performance. Domain knowledge relevant to three types of diseases, namely glaucoma, Diabetic Retinopathy (DR), and skin lesions, is industriously utilised in an attempt to improve the accuracy. For glaucoma, a two-stage framework for automatic Optic Disc (OD) localisation and glaucoma detection is developed, which marked new state-of-the-art for glaucoma detection and OD localisation. To identify DR, a model is proposed that combines coarse-grained classifiers with fine-grained classifiers and grades the disease in four stages with respect to severity. Lastly, different methods of modelling and incorporating metadata are also examined and their effect on a model's classification performance is studied. Confidence in diagnosing a disease is equally important as the diagnosis itself. One of the biggest reasons hampering the successful deployment of CAD in the real-world is that medical diagnosis cannot be readily decided based on an algorithm's output. Therefore, a hybrid CNN architecture is proposed with the convolutional feature extractor trained using point estimates and a dense classifier trained using Bayesian estimates. Evaluation on 13 publicly available datasets shows the superiority of this method in terms of classification accuracy and also provides an estimate of uncertainty for every prediction. Explainability of AI-driven algorithms has become a legal requirement after Europe’s General Data Protection Regulations came into effect. This research presents a framework for easy-to-understand textual explanations of skin lesion diagnosis. The framework is called ExAID (Explainable AI for Dermatology) and relies upon two fundamental modules. The first module uses any deep skin lesion classifier and performs detailed analysis on its latent space to map human-understandable disease-related concepts to the latent representation learnt by the deep model. The second module proposes Concept Localisation Maps, which extend Concept Activation Vectors by locating significant regions corresponding to a learned concept in the latent space of a trained image classifier. This thesis probes many viable solutions to equip a CAD system with PACE. However, it is noted that some of these methods require specific attributes in datasets and, therefore, not all methods may be applied on a single dataset. Regardless, this work anticipates that consolidating PACE into a CAD system can not only increase the confidence of medical practitioners in such tools but also serve as a stepping stone for the further development of AI-driven technologies in healthcare

Self-Organized Coverage and Capacity Optimization for Cellular Mobile Networks

Die zur Erfüllung der zu erwartenden Steigerungen übertragener Datenmengen notwendige größere Heterogenität und steigende Anzahl von Zellen werden in der Zukunft zu einer deutlich höheren Komplexität bei Planung und Optimierung von Funknetzen führen. Zusätzlich erfordern räumliche und zeitliche Änderungen der Lastverteilung eine dynamische Anpassung von Funkabdeckung und -kapazität (Coverage-Capacity-Optimization, CCO). Aktuelle Planungs- und Optimierungsverfahren sind hochgradig von menschlichem Einfluss abhängig, was sie zeitaufwändig und teuer macht. Aus diesen Grnden treffen Ansätze zur besseren Automatisierung des Netzwerkmanagements sowohl in der Industrie, als auch der Forschung auf groes Interesse.Selbstorganisationstechniken (SO) haben das Potential, viele der aktuell durch Menschen gesteuerten Abläufe zu automatisieren. Ihnen wird daher eine zentrale Rolle bei der Realisierung eines einfachen und effizienten Netzwerkmanagements zugeschrieben. Die vorliegende Arbeit befasst sich mit selbstorganisierter Optimierung von Abdeckung und Übertragungskapazität in Funkzellennetzwerken. Der Parameter der Wahl hierfür ist die Antennenneigung. Die zahlreichen vorhandenen Ansätze hierfür befassen sich mit dem Einsatz heuristischer Algorithmen in der Netzwerkplanung. Im Gegensatz dazu betrachtet diese Arbeit den verteilten Einsatz entsprechender Optimierungsverfahren in den betreffenden Netzwerkknoten. Durch diesen Ansatz können zentrale Fehlerquellen (Single Point of Failure) und Skalierbarkeitsprobleme in den kommenden heterogenen Netzwerken mit hoher Knotendichte vermieden werden.Diese Arbeit stellt einen "Fuzzy Q-Learning (FQL)"-basierten Ansatz vor, ein einfaches Maschinenlernverfahren mit einer effektiven Abstraktion kontinuierlicher Eingabeparameter. Das CCO-Problem wird als Multi-Agenten-Lernproblem modelliert, in dem jede Zelle versucht, ihre optimale Handlungsstrategie (d.h. die optimale Anpassung der Antennenneigung) zu lernen. Die entstehende Dynamik der Interaktion mehrerer Agenten macht die Fragestellung interessant. Die Arbeit betrachtet verschiedene Aspekte des Problems, wie beispielsweise den Unterschied zwischen egoistischen und kooperativen Lernverfahren, verteiltem und zentralisiertem Lernen, sowie die Auswirkungen einer gleichzeitigen Modifikation der Antennenneigung auf verschiedenen Knoten und deren Effekt auf die Lerneffizienz.Die Leistungsfähigkeit der betrachteten Verfahren wird mittels eine LTE-Systemsimulators evaluiert. Dabei werden sowohl gleichmäßig verteilte Zellen, als auch Zellen ungleicher Größe betrachtet. Die entwickelten Ansätze werden mit bekannten Lösungen aus der Literatur verglichen. Die Ergebnisse zeigen, dass die vorgeschlagenen Lösungen effektiv auf Änderungen im Netzwerk und der Umgebung reagieren können. Zellen stellen sich selbsttätig schnell auf Ausfälle und Inbetriebnahmen benachbarter Systeme ein und passen ihre Antennenneigung geeignet an um die Gesamtleistung des Netzes zu verbessern. Die vorgestellten Lernverfahren erreichen eine bis zu 30 Prozent verbesserte Leistung als bereits bekannte Ansätze. Die Verbesserungen steigen mit der Netzwerkgröße.The challenging task of cellular network planning and optimization will become more and more complex because of the expected heterogeneity and enormous number of cells required to meet the traffic demands of coming years. Moreover, the spatio-temporal variations in the traffic patterns of cellular networks require their coverage and capacity to be adapted dynamically. The current network planning and optimization procedures are highly manual, which makes them very time consuming and resource inefficient. For these reasons, there is a strong interest in industry and academics alike to enhance the degree of automation in network management. Especially, the idea of Self-Organization (SO) is seen as the key to simplified and efficient cellular network management by automating most of the current manual procedures. In this thesis, we study the self-organized coverage and capacity optimization of cellular mobile networks using antenna tilt adaptations. Although, this problem is widely studied in literature but most of the present work focuses on heuristic algorithms for network planning tool automation. In our study we want to minimize this reliance on these centralized tools and empower the network elements for their own optimization. This way we can avoid the single point of failure and scalability issues in the emerging heterogeneous and densely deployed networks.In this thesis, we focus on Fuzzy Q-Learning (FQL), a machine learning technique that provides a simple learning mechanism and an effective abstraction level for continuous domain variables. We model the coverage-capacity optimization as a multi-agent learning problem where each cell is trying to learn its optimal action policy i.e. the antenna tilt adjustments. The network dynamics and the behavior of multiple learning agents makes it a highly interesting problem. We look into different aspects of this problem like the effect of selfish learning vs. cooperative learning, distributed vs. centralized learning as well as the effect of simultaneous parallel antenna tilt adaptations by multiple agents and its effect on the learning efficiency.We evaluate the performance of the proposed learning schemes using a system level LTE simulator. We test our schemes in regular hexagonal cell deployment as well as in irregular cell deployment. We also compare our results to a relevant learning scheme from literature. The results show that the proposed learning schemes can effectively respond to the network and environmental dynamics in an autonomous way. The cells can quickly respond to the cell outages and deployments and can re-adjust their antenna tilts to improve the overall network performance. Additionally the proposed learning schemes can achieve up to 30 percent better performance than the available scheme from literature and these gains increases with the increasing network size

Poster: Link between Bias, Node Sensitivity and Long-Tail Distribution in trained DNNs

Owing to their remarkable learning (and relearning) capabilities, deep neural networks (DNNs) find use in numerous real-world applications. However, the learning of these data-driven machine learning models is generally as good as the data available to them for training. Hence, training datasets with long-tail distribution pose a challenge for DNNs, since the DNNs trained on them may provide a varying degree of classification performance across different output classes. While the overall bias of such networks is already highlighted in existing works, this work identifies the node bias that leads to a varying sensitivity of the nodes for different output classes. To the best of our knowledge, this is the first work highlighting this unique challenge in DNNs, discussing its probable causes, and providing open challenges for this new research direction. We support our reasoning using an empirical case study of the networks trained on a real-world dataset.Comment: To appear at the 16th IEEE International Conference on Software Testing, Verification and Validation (ICST 2023), Dublin, Irelan

On Interpretability of Deep Learning based Skin Lesion Classifiers using Concept Activation Vectors

Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology. However, the acceptance of these Computer-Aided Diagnosis (CAD) systems in real clinical setups is severely limited primarily because their decision-making process remains largely obscure. This work aims at elucidating a deep learning based medical image classifier by verifying that the model learns and utilizes similar disease-related concepts as described and employed by dermatologists. We used a well-trained and high performing neural network developed by REasoning for COmplex Data (RECOD) Lab for classification of three skin tumours, i.e. Melanocytic Naevi, Melanoma and Seborrheic Keratosis and performed a detailed analysis on its latent space. Two well established and publicly available skin disease datasets, PH2 and derm7pt, are used for experimentation. Human understandable concepts are mapped to RECOD image classification model with the help of Concept Activation Vectors (CAVs), introducing a novel training and significance testing paradigm for CAVs. Our results on an independent evaluation set clearly shows that the classifier learns and encodes human understandable concepts in its latent representation. Additionally, TCAV scores (Testing with CAVs) suggest that the neural network indeed makes use of disease-related concepts in the correct way when making predictions. We anticipate that this work can not only increase confidence of medical practitioners on CAD but also serve as a stepping stone for further development of CAV-based neural network interpretation methods.Comment: Accepted for the IEEE International Joint Conference on Neural Networks (IJCNN) 202

Design Of Intelligent Stick Based On Microcontroller With GPS Using Speech IC

For visually impaired persons the endeavors and researchers have spent the decades to develop an intelligent and smart stick to protect and alert them from obstacles. This paper proposes a new thought developing an intelligent stick equipped with GPS navigation system, which detect the obstacles in path and gives information about their location using GPS coordinates. The combination of ultrasonic sensors and GPS will detect the obstacles and determine the position and will gives information about location through Bluetooth.DOI:http://dx.doi.org/10.11591/ijece.v2i6.162

MANDIBLE ANGLE FRACTURES - EFFECT OF TREATMENT ON OCCLUSAL STABILITY AND SOFT TISSUE

Background: Road Traffic Accidents (RTA) is still the leading cause of all mandibular fractures. The incidence of fractures involving the mandibular angle fractures are stated by most authors to be the second common fractures with a male to female ration of 2:1. Mandibular angle fractures may cause limited mouth opening, and disturbed occlusion, malocclusion resulting from this fracture is due to upward push of posterior segment resulting in premolar contact at ipsilateral molar region. Therefor aim of the treatment is to re-establish the occlusal stability for normal function. Methods: The study followed a   prospective design and was conducted at Oral and Maxillofacial Surgery department, king Salman hospital, Riyadh Saudi Arabia. Demographic data (Age, gender) and complete medical history were obtained from all patients. All patients were requested to fill the consent form in their native language. A Qusai experimental randomised trial conducted between manual reduction group and arch bar elastic group and P value of <0.05 was considered significant. All analysis was done on SPSS version 18.0. Results: Total 86-patients with age above 12, were included in the study in which 29 participants (33.7%) were female and 57-participants (66.2%) were male. On the basis of random selection,  these were divided into two equal groups. Soft tissue injury higher in arch bar elastic group (62.7%) as compared to manual reduction group (3.7%). A statistically-significant association was found between arch bar group and manual reduction group (P < 0.0001). The patients treated with arch bar elastics showed a significantly higher gingivitis as compared to the healthy patients. In our study intraoral approach and upper boarder single titinium plate (2mm) with 2x7mm titinum screws two on eac side of facture, were common in both groups. The stability of occlusion and soft tissue injury were two post-operative findings to document. Conclusion: Patient treated with manual reduction faced less post-operative complications like soft tissue injury and gingiva injury when compared with arch bar elastic group method. Based on this study manual reduction can prevent iatrogenic soft tissue injury and reestablish occlusion, which is the primary goal of treatment