LAJU PERTUMBUHAN BUDIDAYA ELVER ANGUILLA BICOLOR BICOLOR PADA KOLAM SISTEM SIRKULASI

Ikan Sidat merupakan salah satu komoditas yang bernilai tinggi di pasar global dalam sektor pangan. Hal tersebut dikarenakan tingginya nilai gizi yang terkandung dalam tubuh ikan sidat. Permintaan pasar yang tinggi dan keterbatasan stok sidat menyebabkan harga jual sidat tinggi dan membuka peluang bisnis yang cukup menjanjikan bagi pembudidaya lokal. Kesesuaian kualitas air untuk dijadikan habitat budidaya ikan sidat menjadi salah satu parameter keberhasilan dalam kegiatan budidaya ikan sidat. Penerapan sistem sirkulasi berperan dalam menjaga kualitas air budidaya ikan sidat karena dapat membantu distribusi oksigen dan keseimbangan biologis dalam lingkungan budidaya. Tujuan dari penelitian ini ialah pemantauan dan pengelolaan kualitas air terhadap kondisi pertumbuhan, kinetika laju pertumbuhan, dan mortalitas budidaya elver Anguilla bicolor bicolor. Tahapan penelitian yang dilakukan meliputi pembudidayaan elver dengan sistem sirkulasi, pengukuran massa, pemantauan jumlah kematian, dan pemantauan kualitas air (TDS, pH, DO, nitrit, nitrat, dan suhu). Nilai rata-rata kualitas air untuk budidaya elver Anguilla bicolor bicolor yaitu TDS 196 ppm ± 4,74 ; pH 7,46 ± 0,16 ; DO 6,89 ± 0,12 ppm ; nitrit 3,53 ± 2,17 ppm ; nitrat 1,06 ± 0,65 ppm ; suhu 26,8 ± 0,75 °C. Elver mengalami pertumbuhan massa sebesar 1,562 kg dengan laju pertumbuhan spesifik sebesar 0.79% perhari dan konstanta laju pertumbuhan massa elver sebesar 0,0521 gram perhari. Jumlah kematian elver sebanyak 13 ekor dengan mortalitas sebesar 1,85% dan tingkat kelangsungan hidup (SR) sebesar 98,15%. Kata kunci: ikan sidat, elver, Anguilla bicolor, budidaya, pertumbuhan, mortalitas, kualitas ai

The effect of calorie restricted diet on anthropometric and biochemical parameters in Sprague Dawley rats

Purpose Calorie restricted diets are known to improve health and promote healthy aging. This happens because of controlled inflammation and metabolism in the body. This study aims to evaluate the differences in anthropometric and biochemical parameters in Sprague Dawley (SD) rats because of consumption of a calorie restricted diet. Design/methodology/approach The study divided SD rats (n = 15) into 3 groups consuming high calorie intake (HCI), medium calorie intake and low calorie intake (LCI). Anthropometric parameters were determined through measurement of abdominal circumference (AC), thoracic circumference (TC), body length and body weight (BW). Biochemical parameters analyzed in this study were fasting blood glucose level and full blood lipid profile. Nutritional status was obtained based on food consumption, energy intake (EI) and food efficiency rate. Measurements were taken for a period of four weeks. Findings Analysis on anthropometric parameters indicates a significant difference in mean BW between HCI (230.44 ± 1.47 g) and LCI (188.54 ± 1.50 g). There is a significant difference in abdominal TC ratio (p < 0.001; F = 13.599) in the LCI group (1.01 ± 0.00714) compared to the HCI group (1.04 ± 0.00858). Post hoc for nutrition parameters indicates a significant difference in mean EI between HCI (9.71 ± 0.006 kJ) and LCI (3.21 ± 0.001 kJ). There is a significant effect (p < 0.0001; F = 3042872.02) of EI on rats in all three groups. HDL levels were significantly higher (p < 0.0001; F = 1536.89) in the LCI group (68.60 ± 0.55 mg/dL) compared to the HCI group (49.40 ± 0.55 mg/dL). The Pearson’s correlation results show a strong positive correlation in EI with BW (p < 0.01; r = 0.988), AC (p < 0.01; r = 0.970) and body mass index (p < 0.01; r = 0.972). Originality/value Low calorie diet has been proven to affect anthropometric development and has shown improvements in biochemical parameters of the rats. This may result in healthy aging which could prevent later-life diseases

Antimicrobial Activity of Probiotics from Dairy Milk Products against Foodborne Pathogens

Probiotic products are one of solution in order to treat and prevent foodborne disease. The efficiency of probiotic in dairy milk products in inhibiting and killing Escherichia coli Ol 57:H7, Vibrio cholera, Bacillus Cereus and Listeria monocytogenes has not been fully elucidated. These foodborne become problematic because theirs resistance towards antibiotics. Consumption of probiotics in daily life can help in improving bowel diseases lead to treat foodborne disease and food safety in food industry. The main objectives of this study to prove the antimicrobial potential of probiotics strains from different source of dairy milk against pathogenic bacteria. Eight brand of probiotic dairy milks was compared. Seven of eight probiotic dairy milks products showed bacteriostatic properties against four strains of foodborne pathogens. Among the tested commercial probiotics products, Yakult and Vitagen showed the most among highest zone of inhibition probiotic in dairy milk products by having 6 mm to 7 mm inhibition zone compared to the control and both show antimicrobial activity. Only Cheddar cheese did not show any antimicrobial properties against foodborne pathogen tested. Therefore, probiotic is good use in the treat and prevent foodbome disease

Proceedings of the 3rd International Conference on Community Engagement and Education for Sustainable Development

This proceeding contains articles on the various ideas of the academic community presented at The 3rd International Conference on Community Engagement and Education for Sustainable Development (ICCEESD 2022) organized by the Universitas Gadjah Mada, Indonesia on 7th-8th December 2022.  ICCEESD is a biannual forum for sharing, benchmarking, and discussing HEI’s activities in developing Education for Sustainable Development towards community engagement. Education for Sustainability as a teaching strategy for resolving community challenges through formal, informal, or non-formal education is expected to benefit from various community service best practices by academics, researchers, and students. The 3rd ICCEESD has “Strengthening Education for Sustainability Towards Better Community Engagement” as its theme this year. It is expected that the 3rd ICCEESD will provide a forum for the presenters and participants to exchange best practices, policies, and conceptual implementation of Education for Sustainability towards better community engagement and explore ideas to address community needs.  Conference Title: 3rd International Conference on Community Engagement and Education for Sustainable DevelopmentConference Theme: Strengthening Education for Sustainability Towards Better Community EngagementConference Acronyms: ICCEESD 2022Conference Date: 7th-8th December 2022Conference Location: Grand Rohan Jogja Yogyakarta, IndonesiaConference Organizer: Universitas Gadjah Mada, Indonesi

Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research