Photovoltaic effect in an electrically tunable van der Waals heterojunction

Semiconductor heterostructures form the cornerstone of many electronic and optoelectronic devices and are traditionally fabricated using epitaxial growth techniques. More recently, heterostructures have also been obtained by vertical stacking of two-dimensional crystals, such as graphene and related two- dimensional materials. These layered designer materials are held together by van der Waals forces and contain atomically sharp interfaces. Here, we report on a type- II van der Waals heterojunction made of molybdenum disulfide and tungsten diselenide monolayers. The junction is electrically tunable and under appropriate gate bias, an atomically thin diode is realized. Upon optical illumination, charge transfer occurs across the planar interface and the device exhibits a photovoltaic effect. Advances in large-scale production of two-dimensional crystals could thus lead to a new photovoltaic solar technology.Comment: 26 pages, 14 figures, Nano Letters 201

Wage curve: theory and empirics (in Russian)

We consider the concept of a wage curve describing a negative relationship between unemployment and wages. We suggest an explanation of the wage curve using a number of theoretical labor market models, and present an empirical result of its determination for Russia obtained from analysis of regional data.Russia, wage curve, labor market models, panel data

Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV): A threat for xenotransplantation?

The potential for a donor-derived transmission of porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV) to the recipient has been recognized since pigs were considered candidate donors for xenotransplantation. This review gives a short description of the viral properties and summarizes the current evidence of the effects of PCMV/PRV transmission in preclinical xenotransplantation. Despite evidence that PCMV/PRV does not infect human and non-human primate cells, activation in the transplanted organ and detrimental systemic complications have been described. As PCMV/PRV is a herpesvirus able to establish latency, the importance of adequate screening of donor pigs is emphasized, as no efficient treatment is available. Furthermore, easy and successful ways of elimination of PCMV/PRV from pig herds are indicated

Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV): A threat for xenotransplantation?

The potential for a donor-derived transmission of porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV) to the recipient has been recognized since pigs were considered candidate donors for xenotransplantation. This review gives a short description of the viral properties and summarizes the current evidence of the effects of PCMV/PRV transmission in preclinical xenotransplantation. Despite evidence that PCMV/PRV does not infect human and non-human primate cells, activation in the transplanted organ and detrimental systemic complications have been described. As PCMV/PRV is a herpesvirus able to establish latency, the importance of adequate screening of donor pigs is emphasized, as no efficient treatment is available. Furthermore, easy and successful ways of elimination of PCMV/PRV from pig herds are indicated

Preliminary speech recognition results after cochlear implantation in patients with unilateral hearing loss: a case series

<p>Abstract</p> <p>Introduction</p> <p>Cochlear implants known to provide support in individuals with bilateral hearing loss may also be of great benefit for individuals with unilateral hearing loss. This case report demonstrates the positive effects of cochlear implantation on speech understanding in noise conditions in patients with unilateral hearing loss and normal hearing on the contralateral side. To the best of our knowledge, the data presented here are from the first few cases to receive a cochlear implant for unilateral hearing loss.</p> <p>Case presentation</p> <p>Four Caucasian German men, two aged 48 and the others aged 51 and 57 years old, with post-lingual unilateral hearing loss and normal hearing on the contralateral side were implanted with a cochlear implant. All our patients were members of the German army. Before and after implantation, they were given a battery of speech tests in different hearing conditions to assess the effect of unilateral cochlear implantation on speech understanding in noise conditions. Test results showed that all patients benefited from unilateral cochlear implantation, particularly in terms of speech understanding in noise conditions.</p> <p>Conclusions</p> <p>Unilateral cochlear implantation might be a successful treatment method for patients with unilateral hearing loss not benefiting from alternative treatment options. The results of this case report open up the field of cochlear implantation for expanded criteria and new areas of research.</p

Functional expression of a human TCRβ gene in transgenic mice

A functionally rearranged TCRβ (Tcrb) gene was isolated from a cloned human T helper cell recognizing the CS.T3 epitope of Plasmodium falciparum with HLA-DR2. Transgenic mice were generated by co-injection of the human gene together with the mouse Tcrb enhancer. Analysis of transgenic mice shows that the functional Tcrb gene of xenogenic, i.e. human, origin exerts allelic exclusion of endogenous Tcrb genes. Cytofluorometric analysis revealed expression of the human TCRβ chain on virtually all thymocytes and peripheral T cells together with endogenous TCRβ chains and CD3 components. No surface expression of mouse TCRβ chain or rearrangement of endogenous Tcr genes was detectable. Expression of the hybrid receptor causes a reduction in the number of thymocytes and a bias for CD4+CD8− T cells in the thymus as compared with non-transgenic littermates. Peripheral transgenic T cells mount a normal prollferative response against allogenelc targets in mixed lymphocyte reactions. These results show that a hybrid mouse/human TCR is able to pass positive and negative selection in the thymus, and is functional in transgenic mic