12 research outputs found
Culture and Terrorism: Cultural Heritage of Historic Maritime Cities in Counter-Terrorism Strategies
PodruÄje kulture i kulturalnih studija izvan je sustavnog interesa sigurnosnih studija i policyja (provedbene politike) nacionalne sigurnosti generalno i studija terorizma i protuteroristiÄkih policyja partikularno. U radu se razmatra jedan od aspekata odnosa kulture i (protu)terorizma: kultura kao meta ugrožavanja. Povijesni su gradovi upravo podruÄja koja obiluju kulturom i kulturnom baÅ”tinom. Kultura i kulturna baÅ”tina selektirana su meta terorizma. Prema autoritativnoj Global Terrorism Database kulturna baÅ”tina (religijski objekti/institucije) u razdoblju od 1970. do 2016. bila je meta 4304 teroristiÄka udara diljem svijeta Å”to je cca 2,5 % od ukupnog broja od170.350 teroristiÄkih akata koliko ih se dogodilo u promatranom razdoblju. U radu se s aspekta (protu)terorizma, metodom sluÄajnog uzorka, analizira i stanje sigurnosti u pomorskim lukama hrvatskih povijesnih gradova te brodova koji u njima borave u odnosu na terorizam te iznose policy preporuke za jaÄanje protuteroristiÄkih kapaciteta.The field of culture and cultural studies is beyond the systematic interest of security studies and policies (implemented politics) of national security in general, and the study of terrorism and counter-terrorism policies in particular. This paper deals with one aspect of the relationship between culture and (counter) terrorism: culture as a target. Historic cities are precisely the areas that are rich in culture and cultural heritage. Culture and cultural heritage are targets of terrorism. According to the authoritative Global Terrorism Database, cultural heritage (religious objects/institutions) was a target of 4304 terrorist
attacks worldwide from 1970 to 2016, which is approximately 2.5% of the total number of 170,350 attacks within the observed period. This paper deals with the aspect of (counter)terrorism, by means of a random sample, analyzing the security of Croatian historical citiesā
maritime ports and the ships residing in them in relation to terrorism and providing policy recommendations for the strengthening of counter-terrorism capacities
Vascular Endothelial Growth Factor and Intratumoral Microvessel Density as Prognostic Factors in Endometrial Cancer
The aim of this research was to determine the VEGF A expression in tumor cells and the intratumoral microvessel density and their prognostic significance in the survival of the subjects. 87 subjects were monitored retrospectively for a period of 60 to 132 months. The subjects were treated at the Department of Obstetrics and Gynecology of Osijek University Hospital Center, Croatia. We analysed standard clinical, pathohistological and therapeutical prognostic factors, intratumoral microvessel density and expression of VEGF A. Five-year survival was calculated by the life chart method and presented graphically by Kaplan-Meier curves. Reaching conclusions on statistical hypotheses in this paper was done with a reliability level p<0.05. Of the analyzed clinical prognostic factors, those which proved to be statistically significant and independent prognostic factors were age and clinical stage of the disease, and of pathohistologic ones it was the depth of myometrial invasion and VEGF expression. An elevated VEGF expression is associated with deep myometrial invasion, poorly differentiated tumors, histologic type and intratumoral microvessel density to a statistically significant degree. Elevated VEGF expression, age, FIGO stage and depth of myometrial invasion play a significant prognostic role in patients with endometrial cancer. VEGF receptors could be a target for adjuvant therapy in VEGF positive endometrial cancer
Dozimetrijska verifikacija radioterapijskih planova intezitet-modulirajuÄe radioterapije u bolesnika s rakom prostate
Intensity modulated radiotherapy (IMRT) has become widely used as a standard
radiation therapy technique for the treatment of localized prostate cancer. The transition from conformal
radiotherapy (3D CRT) to a more complex IMRT technique triggered the need for more thorough
verification of the accuracy in the dose delivery. In this work we present the clinical workflow
and the results of patient specific quality assurance (PSQA) procedures for 40 prostate cancer patients
who have been treated with step and shot IMRT ever since its implementation in our routine clinical
practice. PSQA procedures include dosimetric verification of each treatment plan with dedicated
rotational phantom and high-resolution matrix detector system Octavius 4D (PTW Freiburg) that
allows three-dimensional comparison of the calculated and delivered radiation dose distribution. Our
results proved the compliance with the universal tolerance limits recommended for those procedures
(1), assuring the safety of the treatment and providing the possibility for the adoption of more stringent
constraints in the future.Radioterapija moduliranog intenziteta (eng. intensity modulated radiotherapy āIMRT) u posljednjem desetljeÄu je postala
uobiÄajena radioterapijska metoda za terapiju lokaliziranih karcinoma prostate. Prelazak s konformalne radioterapije na napredniju
i tehniÄki složeniju IMRT tehniku, donio je i potrebu za detaljnijom i sveobuhvatnom provjerom toÄnosti isporuke
doze zraÄenja. U ovom radu predstavljamo provoÄenje postupaka dozimetrijske verifikacije radioterapijskih planova poznatih
pod engleskim nazivom patient specific QA (PSQA) te rezultate za 40 bolesnika s karcinomom prostate koji su primili
IMRT terapiju. U tu svrhu koristimo posebni dozimetrijski sustav s rotacijskim fantomom i visoko razluÄivom detektorskom
matricom, Octavius 4D (PTW Freiburg). Pokazalo se kako su sva dobivena odstupanja izmeÄu planirane i mjerene trodimenzionalne
raspodjele doze bila unutar preporuÄenih tolerancija (1) Å”to nam daje povjerenje u sigurnost provoÄenja ovakve
terapije te otvara moguÄnost za primjenu strožijih ograniÄenja u buduÄnosti
CLINICAL RECOMMENDATIONS FOR DIAGNOSING, TREATMENT AND MONITORING OF PATIENTS WITH OVARIAN CANCER ā CROATIAN ONCOLOGY SOCIETY AND CROATIAN SOCIETY FOR GYNECOLOGY AND OBSTETRICS AS CROATIAN MEDICAL ASSOCIATION UNITS AND CROATIAN SOCIETY OF GYNECOLOGICAL ONCOLOGY
Rak jajnika i jajovoda po uÄestalosti je peta zloÄudna bolest žena u Hrvatskoj. HistoloÅ”ki je rak jajnika najÄeÅ”Äe epitelnog podrijetla, i to seroznog podtipa. RjeÄi su razliÄiti neepitelni malignomi jajnika, a posebnu skupinu Äine epitelni karcinomi niskoga zloÄudnog potencijala karakterizirani neinvazivnoÅ”Äu, kliniÄki indolentnim tijekom i dobrom prognozom te primarni rak potrbuÅ”nice i rak jajovoda. KliniÄki su ovi zloÄudni tumori u ranim stadijima razvoja uglavnom asimptomatski, zbog Äega se najÄeÅ”Äe dijagnosticiraju u kasnijim stadijima bolesti. Dijagnoza se potvrÄuje patohistoloÅ”kim nalazom, a iznimno citoloÅ”kim nalazom nakon provedene dijagnostiÄke obrade. O lijeÄenju odluÄuje multidisciplinarni tim uzimajuÄi u obzir dob, opÄe stanje i komorbiditete bolesnice, kao i obilježja samog tumora ukljuÄujuÄi stadij bolesti, histoloÅ”ki tip i gradus tumora. Principi lijeÄenja primarnog raka potrbuÅ”nice i jajovoda temelje se na principima lijeÄenja epitelnog raka jajnika koji obuhvaÄaju primjenu kirurÅ”kih zahvata, kemoterapije, imunoterapije i hormonske terapije, kao i suportivno-simptomatskih mjera tijekom cijelog lijeÄenja. Razlikuje se terapijski pristup rjeÄim, neepitelnim histoloÅ”kim tipovima tumora koji se ÄeÅ”Äe dijagnosticiraju u ranim stadijima bolesti, imaju indolentniji tijek pa se kod ovih bolesnica ÄeÅ”Äe primjenjuju poÅ”tedni kirurÅ”ki zahvati s ciljem oÄuvanja plodnosti. U tekstu koji slijedi predstavljene su kliniÄke upute s ciljem standardizacije postupaka i kriterija postavljanja dijagnoze, lijeÄenja te praÄenja bolesnica s rakom jajnika, jajovoda i potrbuÅ”nice u Republici Hrvatskoj.Ovarian cancer together with fallopian tube represents the fifth most common female cancer in the Republic of Croatia. Epithelial ovarian cancer, serous subtype, encompasses most of malignant ovarian neoplasms. Less common are various non-epithelial ovarian malignancies. A special group consists of epithelial carcinomas of low malignant potential with clinically indolent flow, good prognosis and no invasion, and primary cancer of the peritoneum and fallopian tube cancer. Clinically, these malignant tumors are generally asymptomatic in early stages, and usually diagnosed in advanced stages. The diagnosis is confirmed by pathological examination, and occasionally, cytological findings after completing diagnostic procedures. Multidisciplinary team makes treatment decisions, taking into account age, general condition and comorbidities of the patient and characteristics of the tumor itself, including disease stage, histological type and grade of the tumor. The principles of treatment of primary peritoneal and fallopian tube cancer are based on the principles of treatment of epithelial ovarian cancer involving surgery, chemotherapy, immune and hormone therapy, and symptomatic-supportive care throughout the treatment. Less common histological types have a different treatment approach being more frequently diagnosed in the early stages of the disease, have more indolent flow, so in these patients conservative surgeries with the goal of preserving fertility are more often employed. The following text presents the clinical guidelines in order to standardize the procedures and criteria for the diagnosis, management, treatment and monitoring of patients with ovarian carcinoma, fallopian tube and primary peritoneal cancer in the Republic of Croatia
CLINICAL RECOMMENDATIONS FOR DIAGNOSING, TREATMENT AND MONITORING OF PATIENTS WITH ENDOMETRIAL CANCER ā CROATIAN ONCOLOGY SOCIETY AND CROATIAN SOCIETY FOR GYNECOLOGY AND OBSTETRICS AS CROATIAN MEDICAL ASSOCIATION UNITS AND CROATIAN SOCIETY OF GYNECOLOGICAL ONCOLOGY
Rak trupa maternice javlja se u veÄini sluÄajeva u poslijemenopauzalnih žena, a najÄeÅ”Äe se oÄituje ginekoloÅ”kim krvarenjem. Nakon raka jajnika i vrata maternice treÄi je uzrok smrti žena od raka spolnog sustava. Dijagnoza se postavlja patohistoloÅ”kim pregledom kiretmana ili bioptata, a definitivni stadij bolesti utvrÄuje se analizom uzoraka dobivenih histerektomijom i obostranom salpingoovariektomijom sa zdjeliÄnom i paraaortalnom limfadenektomijom. U tekstu koji slijedi sadržane su kliniÄke upute s ciljem standardizacije postupaka i kriterija postavljanja dijagnoze, lijeÄenja i praÄenja bolesnica s rakom trupa maternice u Republici Hrvatskoj.Uterine cancer occurs mainly in postmenopausal women, usually as vaginal bleeding. Following ovarian and cervical cancer it is the third most common cause of female reproductive system cancer death. Diagnosis is set by analyzing samples obtained via hysterectomy with salpingo-oophorectomy and pelvic / paraaortal lymphadenectomy. The following text presents the clinical guidelines in order to standardize the procedures and criteria for the diagnosis, treatment and monitoring of patients with uterine cancer in the Republic of Croatia
RužiÄka days : International conference 16th RužiÄka Days āToday Science ā Tomorrow Industryā : Proceedings
Proceedings contains articles presented at Conference divided into sections: open lecture (1), chemical analysis and synthesis (3), chemical and biochemical engineering (8), food technology and biotechnology (8), medical chemistry and pharmacy (3), environmental protection (11) and meeting of young chemists (2)
Vascular endothelial growth factor and intratumoral microvessel density as prognostic factors in endometrial cancer [Vaskularni endotelni Äimbenik rasta i gustoÄa tumorskih kapilara kao prognostiÄki Äimbenik u endometrijskom raku]
The aim of this research was to determine the VEGF A expression in tumor cells and the intratumoral microvessel density and their prognostic significance in the survival of the subjects. 87 subjects were monitored retrospectively for a period of 60 to 132 months. The subjects were treated at the Department of Obstetrics and Gynecology of Osijek University Hospital Center, Croatia. We analysed standard clinical, pathohistological and therapeutical prognostic factors, intratumoral microvessel density and expression of VEGF A. Five-year survival was calculated by the life chart method and presented graphically by Kaplan-Meier curves. Reaching conclusions on statistical hypotheses in this paper was done with a reliability level p < 0.05. Of the analyzed clinical prognostic factors, those which proved to be statistically significant and independent prognostic factors were age and clinical stage of the disease, and of pathohistologic ones it was the depth of myometrial invasion and VEGF expression. An elevated VEGF expression is associated with deep myometrial invasion, poorly differentiated tumors, histologic type and intratumoral microvessel density to a statistically significant degree. Elevated VEGF expression, age, FIGO stage and depth of myometrial invasion play a significant prognostic role in patients with endometrial cancer. VEGF receptors could be a target for adjuvant therapy in VEGF positive endometrial cancer
BLACK CHARTER IN THE REPUBLIC OF CROATIA
Svrha i cilj ovoga rada je sistematizirati, opisati i analizirati oblike, te procijeniti razmjere zastupljenosti ācrnog Äarteraā u Republici Hrvatskoj i formulirati smjernice za njegovo smanjenje i suzbijanje.
Nelegalno iznajmljivanje stranih plovila u naÅ”em moru, popularno nazvano ācrni Äarterā, ima znaÄajan udio u sivoj ekonomiji Republike Hrvatske i državnom proraÄunu iz godine u godinu nanosi golemu i teÅ”ko procjenjivu Å”tetu. Prema dostupnim podacima i procjenama radi se o najmanje deset tisuÄa uglavnom stranih jahti i brodica koje svakog ljeta plove naÅ”im Jadranom i to u nelegalnom iznajmljivanju. Te procjene govore da u punoj turistiÄkoj sezoni, tijekom tri ljetna mjeseca efektivnog rentiranja tih plovila, hrvatski državni proraÄun, samo zbog neplaÄanja PDV-a i poreza na dobit izgubi viÅ”e od 300 milijuna kuna.
U radu je koriÅ”teno viÅ”e znanstvenih metoda, meÄu kojima induktivna i deduktivna metoda, statistiÄka metoda i ekspertna metoda. Primijenjene metode, ukazuju na relativno visok udio zastupljenosti ācrnog Äarteraā u Republici Hrvatskoj i to sve do 2005. godine, kada je donesena nova Uredba o dolasku i boravku stranih jahti i brodica u hrvatskom moru, Å”to je rezultiralo znaÄajnim smanjenjem ācrnog Äarteraā.
Glavni problem je u tome Å”to Äarter tvrtke ne naplaÄuju usluge najma na raÄun svoje tvrtke osnovane u Hrvatskoj, nego izravno u inozemstvo, na raÄun offshore tvrtki. Inozemne Äarter tvrtke zlorabe instituciju privremenog uvoza i moguÄnost povrata PDV-a. Najmom kod Äarter tvrtki i tromjeseÄnim rentiranjem tako uvezenih plovila uz minimalne troÅ”kove, korisnici tih povlastica zaraÄivali su od 50 000 do 80 000 EUR-a.
Svakako je potrebno usklaÄivanje hrvatskog zakonodavstva sa zakonima i standardima EU-a, Å”to nije samo naÅ”a obveza u veÄ pokrenutim pristupnim pregovorima, nego i nužnost, kako bi se izbjegla razliÄita tumaÄenja odreÄenih propisa i razliÄita postupanja carinskih, poreznih i pomorskih tijela u postupanju naspram ācrnom Äarteruā.The purpose and aim of this paper is to systemize, describe and analyze the forms, as well as to estimate the share of āblack charterā in Croatia, and to formulate guidelines for its decrease and control.
Illegal charter of foreign crafts in our waters, known as āblack charterā, accounts for a considerable share of grey economy in Croatia and causes, year by year, a severe damage to the State Budget that is hardly to assess. According to the available data and estimates there are at least ten thousand mainly foreign yachts and boats in our part of the Adriatic Sea every summer that are illegally chartered, and against some estimates due to effective charter of those crafts in high season during three summer months, the Croatian State Budget looses more than Kn 300 million only from non-payment of VAT and profit tax.
A number of methods, including the inductive and deductive ones, statistical and expert methods, have been used in this paper. The methods applied show a comparatively large proportion of āblack charterā in Croatia until 2005 when a new Regulation on Arrival and Stay of Foreign Yachts and Boats in Croatian Water was adopted. However, since then it has been considerably decreased.
The main problem is that the charter companies do not charge the charter services to the account of their company established in Croatia, but directly to the account abroad, to off-shore companiesā account. Foreign charter companies abuse the regulations on temporary import and VAT rebate. By charter with charter companies and through a three-month charter of crafts imported in this way, under minimum costs, the beneficiaries of those benefits used to earn between Eur 50,000 and 80,000.
It is by all means necessary to carry out the approximation of Croatian legislation with EU laws and standards, which is not only required by the accession negotiations opened with the EU, but is also essential in order to avoid different interpretations of certain regulations and different procedures taken by customs, tax and maritime authorities against āblack charterā