1,869 research outputs found
The Role of Non-Recurring Congestion in Massive Hurricane Evacuation Events
The response to a potential disaster can require the evacuation of personnel from a specified area. Generally, such efforts are restricted to the orderly mass departure of individuals across pre-planned and well maintained transportation routes. In the U.S., evacuations of up to 1,000 subjects take place every two to three weeks, with more extreme evacuations involving two million or more every one to three years (TRB, 2008). While evacuation routes are designed to accommodate normal traffic movements, congestion and gridlock can occur as the design capacity of the road system is overwhelmed by the magnitude of vehicles leaving the affected area. The resulting traffic patterns affect the safety and mobility of subjects moving to more secure areas. Adding to this disarray, potential nonrecurring incidents congest traffic patterns even more. Estimates indicate that between fifty and sixty-five percent of traffic congestion is caused by non-recurring traffic incidents with an additional ten percent related to construction and weather (Coifman, 2007). A non-recurring traffic incident is any event that both causes a reduction of roadway capacity, or an abnormal increase in demand, and requires first responders to be dispatched. Stalled vehicles, roadway debris, spilled loads, and crashes fall into this category of incidents. Non-recurring traffic incidents can cause secondary traffic incidents. These incidents further congest the traffic stream and cause delays in clean-up efforts by first-responders. Studies indicate that twenty percent of traffic incidents are secondary incidents, with one out of five resulting in a fatality. In addition to crashes, secondary incidents can include overheated vehicles, out of fuel conditions, and engine stalls. The delay and traffic gridlock associated with traffic incidents is compounded during the evacuation process due to the large numbers of subjects leaving the affected area. These delays and backups result in: ⢠Increased response time by first responders ⢠Lost time resulting in a wider evacuation window ⢠Increased fuel consumption ⢠Reduced air quality and other adverse environmental conditions ⢠Increased potential for more serious secondary incidents resulting from rear end collisions, traffic exiting the route, or exiting to the shoulder of the road ⢠Increased potential of crashes by incidents involving personnel responding to traffic incidents ⢠Negative public image of first responders involved in incident management activities
Fuzzy set theory for cumulative trauma prediction
A widely used fuzzy reasoning algorithm was modified and implemented via an expert system to assess the potential risk of employee repetitive strain injury in the workplace. This fuzzy relational model, known as the Priority First Cover Algorithm (PFC), was adapted to describe the relationship between 12 cumulative trauma disorders (CTDs) of the upper extremity, and 29 identified risk factors. The algorithm, which finds a suboptimal subset from a group of variables based on the criterion of priority, was adopted to enable the inference mechanism of a constructed knowledge-based system to predict CTD occurrence
Heat capacity at the glass transition
A fundamental problem of glass transition is to explain the jump of heat
capacity at the glass transition temperature without asserting the
existence of a distinct solid glass phase. This problem is also common to other
disordered systems, including spin glasses. We propose that if is defined
as the temperature at which the liquid stops relaxing at the experimental time
scale, the jump of heat capacity at follows as a necessary consequence
due to the change of system's elastic, vibrational and thermal properties. In
this picture, we discuss time-dependent effects of glass transition, and
identify three distinct regimes of relaxation. Our approach explains widely
observed logarithmic increase of with the quench rate and the correlation
of heat capacity jump with liquid fragility
Integrated Hybrid System Architecture for Risk Analysis
A conceptual design has been announced of an expert-system computer program, and the development of a prototype of the program, intended for use as a project-management tool. The program integrates schedule and risk data for the purpose of determining the schedule applications of safety risks and, somewhat conversely, the effects of changes in schedules on changes on safety. It is noted that the design has been delivered to a NASA client and that it is planned to disclose the design in a conference presentation
Umbilical artery tone in maternal obesity
Background: The increasing prevalence of obesity constitutes a major health problem in obstetrics with implications for feto-maternal growth and wellbeing. This study investigated and compared the contractile properties of umbilical arteries excised from obese women, with those excised from women with a normal body mass index (BMI).
Methods: Sections of umbilical artery were obtained from umbilical cord samples immediately after delivery and mounted for isometric recording in organ tissue baths under physiological conditions. Cumulative additions of 5-Hydroxytryptamine (5-HT) and Prostaglandin F-2alpha (PgF2alpha) were added in the concentration range of 1 nmol/L to 10 micromol/L. Control vessels were exposed to Krebs physiological salt solution (PSS) only. The resultant effects of each drug addition were measured using the Powerlab hardware unit.
Results: 5-HT exerted a significant effect on human umbilical artery tone at concentrations of 100 nmol/L, 1 micromol/L, and 10 micromol/L in normal (n = 5; P < 0.05) and obese ( n = 5; P < 0.05) women. The contractile effect was significantly greater in vessels from obese women {Mean Maximum Tension (MMT) = 4.2532 g} than in those from women of normal BMI (MMT = 2.97 g; P < 0.05). PgF2alpha exerted a significant contractile effect on vessels at 1 micromol/L and 10 micromol/L concentrations when compared with controls (n = 5; P < 0.05). There was a nonsignificant trend towards an enhanced tone response in vessels from obese women (MMT = 3.02 g; n = 5), in comparison to vessels from women of a normal BMI (MMT = 2.358 g; n = 5; P > 0.05).
Conclusion: These findings support the hypothesis that endogenous regulation of umbilical artery tone is altered in association with maternal obesity. This may be linked to the cardiovascular effects of secretory products of adipose tissue, with implications for the feto-maternal circulation
An exploratory analysis of women’s free-text comments on their Quality of Life in the UK Standardisation of Breast Radiotherapy (START) Trials for early breast cancer
The BBaRTS Healthy Teeth Behaviour Change Programme for preventing dental caries in primary school children: study protocol for a cluster randomised controlled trial
Open Access
This article is distributed under the terms of the Creative Commons Attribution 4.0
International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and
reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to
the Creative Commons license, and indicate if changes were madeThis trial is supported by an unrestricted grant from GlaxoSmithKlin
Training programs in blood diseases: Mayo Clinic Rochester Hematology–Oncology Fellowship Program
The Glass Transition Temperature of Water: A Simulation Study
We report a computer simulation study of the glass transition for water. To
mimic the difference between standard and hyperquenched glass, we generate
glassy configurations with different cooling rates and calculate the
dependence of the specific heat on heating. The absence of crystallization
phenomena allows us, for properly annealed samples, to detect in the specific
heat the simultaneous presence of a weak pre-peak (``shadow transition''), and
an intense glass transition peak at higher temperature.
We discuss the implications for the currently debated value of the glass
transition temperature of water. We also compare our simulation results with
the Tool-Narayanaswamy-Moynihan phenomenological model.Comment: submitted to Phys. Re
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