On statistical properties of traded volume in financial markets

In this article we study the dependence degree of the traded volume of the Dow Jones 30 constituent equities by using a nonextensive generalised form of the Kullback-Leibler information measure. Our results show a slow decay of the dependence degree as a function of the lag. This feature is compatible with the existence of non-linearities in this type time series. In addition, we introduce a dynamical mechanism whose associated stationary probability density function (PDF) presents a good agreement with the empirical results.Comment: 6 pages, 4 figures, 1 table. Based on the talk presented at "News, Expectations and Trends in Statistical Physics, NEXT-SigmaPhi 3rd International Conference. 13-18 August 2005, Kolymbari CRETE" Multi-fractal analysis section remove

Modelo de cuantificación del consumo energético en edificación

The research conducted in this paper focuses on the generation of a model for the quantification of energy consumption in building. This is to be done through one of the most relevant environmental impact indicators associated with weight per m2 of construction, as well as the energy consumption resulting from the manufacturing process of materials used in building construction. The practical application of the proposed model on different buildings typologies in Seville, will provide information regarding the building materials, the subsystems and the most relevant construction elements. Hence, we will be able to observe the impact the built surface has on the environment. The results obtained aim to reference the scientific community, providing quantitative data comparable to other types of buildings and geographical areas. Furthermore, it may also allow the analysis and the characterization of feasible solutions to reduce the environmental impact generated by the different materials, subsystems and construction elements commonly used in the different building types defined in this study.La investigación realizada en el presente trabajo plantea la generación de un modelo de cuantificación del consumo energético en edificación, a través de uno de los indicadores de impacto ambiental más relevantes asociados al peso por m2 de construcción, el consumo energético derivado del proceso de fabricación de los materiales de construcción empleados en edificación. La aplicación práctica del modelo propuesto sobre diferentes tipologías edificatorias en Sevilla aportará información respecto a los materiales de construcción, subsistemas y elementos constructivos más impactantes, permitiendo visualizar la influencia que presenta la superficie construida en cuanto al impacto ambiental generado. Los resultados obtenidos pretenden servir de referencia a la comunidad científica, aportando datos numéricos que podrán ser comparados en otras tipologías y ámbitos geográficos, a la vez que permitirán analizar y precisar mejoras en cuanto al impacto ambiental generado por los diferentes materiales, subsistemas y elementos constructivos habitualmente utilizados en las tipologías edificatorias definidas

Chromatography-Olfactometry Study of the Aroma of Fino Sherry Wines

The aroma of Fino sherry wines produced by industrial biological aging for 0, 1.5, 2.5, 4.5, and 6 years in the Montilla-Moriles region (southern Spain) was studied by gas chromatography-olfactometry. The aroma sensations detected by 3 trained sniffers were classified according to their odor descriptors into 8 odorant series (fruity, empyreumatic, chemical, fatty, balsamic, vegetable, floral, and spicy), describing the aroma profile of the studied wines. The results showed 47 detected odors in the unaged wines, 50 in the 1.5-years-old wines and 59, 61 and 69 in the wines aged 2.5, 4.5, and 6 years, respectively. According to the frequency of the perceived aromas, the fruity and empyreumatic series were the most characteristic odorant series. By exception of chemical, floral and balsamic series without changes during aging of the wines, the remainder series increased their participation during the aging, mainly the fruity, empyreumatic, and fatty series

Aspectos relevantes para el diseño de planes de salud sostenibles orientados a los grupos de interés. Una propuesta basada en la Guía ISO 26000: 2010

Fundamentos : Los planes de salud de las comunidades autónomas pue- den incorporar criterios de desarrollo sostenible en su elaboración. No se han realizado análisis al respecto o propuestas de elaboración e indicadores. El objetivo fue la elaboración de un panel de indicadores de seguimiento orientados al desarrollo sostenible que contribuyan a gestionar los impactos económicos, sociales y medioambientales de los sistemas sanitarios. Método: Se utilizó una variación del método RAND/UCLA o técnica de Delphi modificada. El proceso consistió en un análisis bibliográfico y de contexto de las materias y asuntos relacionados con sanidad y responsabi- lidad social tomando como base ISO 26000:2010. Se realizó una encuesta mediante muestreo intencional a una selección de 70 miembros expertos de los grupos de interés identificados y un grupo de discusión para determinar el consenso sobre los asuntos tratados en la encuesta. La investigación fue realizada en 2015. Resultados: De la revisión bibliográfica se obtuvieron 33 asuntos rela - cionados con sanidad incluidos en ISO 26000:2010. De la encuesta, 7 resul- taron relevantes con alto consenso, 8 de relevancia y consenso medio y 18 con menor relevancia y alto nivel de disenso. El grupo de expertos excluyó 4 de los 18 asuntos con menor consenso. Conclusiones: 29 de los 33 asuntos incluidos en el trabajo, repartidos en las 7 materias fundamentales contenidas en la guía ISO 26000 de res- ponsabilidad social, resultaron relevantes para los grupos de interés en re- lación con su posible inclusión en los planes de salud. Se elaboró un panel de indicadoresBackground: Health plans of the Spanish autonomous communities can incorporate sustainable development criteria in its development. There have been no analysis or proposals about development and indicators. The goal is to add a contribution to help build better health plans aimed at sustainable de- velopment and help to manage economic, social and environmental impacts of health systems criteria. Methods: We used a variation of the RAND/UCLA or modified Delphi technique method. The process consisted of a bibliographical and context matters and issues related to health and social responsibility analysis based on ISO 26000: 2010. A survey by deliberately to a selection of 70 expert members of the identified stakeholders was carried out and a discussion group was held to determine the consensus on the issues addressed in the survey sample. The research was conducted in 2015. Results: From the literature review 33 health issues included in ISO 26000:2010 were obtained. 7 survey proved relevant high consensus, 8 re- levance and average consensus and 18 with less relevance and high level of dissent. The expert group excluded 4 of the 18 subjects with less consensus. Conclusions: 29 issues included 33 at work, divided into 7 subjects contained in the guide ISO 26000 of social responsibility, were relevant stakeholders regarding possible inclusion in health plans. Considering the direct relationship published by ISO (International Organization for Stan- dardization) among the issues ISO 26000 and the economic, social and envi- ronmental indicators in GRI (Global Reporting Initiative) in its G4 version, a panel with monitoring indicators related to relevant issues were elaborated.Los autores agradecen el apoyo recibido por la Universidad Jaume I (proyecto P1.1B2013-48) y el Máster en Sostenibilidad y Responsabilidad Social Corporativa (UJI-UNED)

Numerical indications of a q-generalised central limit theorem

We provide numerical indications of the $q$-generalised central limit theorem that has been conjectured (Tsallis 2004) in nonextensive statistical mechanics. We focus on $N$ binary random variables correlated in a {\it scale-invariant} way. The correlations are introduced by imposing the Leibnitz rule on a probability set based on the so-called $q$-product with $q \le 1$. We show that, in the large $N$ limit (and after appropriate centering, rescaling, and symmetrisation), the emerging distributions are $q_e$-Gaussians, i.e., $p(x) \propto [1-(1-q_e) \beta(N) x^2]^{1/(1-q_e)}$, with $q_e=2-\frac{1}{q}$, and with coefficients $\beta(N)$ approaching finite values $\beta(\infty)$. The particular case $q=q_e=1$ recovers the celebrated de Moivre-Laplace theorem.Comment: Minor improvements and corrections have been introduced in the new version. 7 pages including 4 figure

Extraction of phenolic compounds in controlled macerations of Pedro Ximenez grapes

Crushed grapes of cv. Pedro Ximenez were macerated together with their must for 4, 16, 24 and 48 h at temperatures of 10, 15 and 25°C. The musts obtained after pressing were used for the determination of 14 phenolic compounds from the following fractions: hydroxybenzoic acids, hydroxycinnamic acids, other nonflavonoids, flavan-3-ols and flavonols. The temperature was found not to exert a marked influence on the extraction of the phenolic compounds in the first 16 h of maceration. After that time, however, it had a significant effect, so maceration times longer than 16 h are inadvisable unless subsequent oxidation is applied. The analytical results obtained showed that the flavan-3-ols, catechin and epicatechin were extracted at the highest rates, related with maceration temperature, followed by hydroxbenzoic acids, other nonflavonoids, hydroxycinnamic acids and flavonols. The flavan-3-ol fraction was also extracted in higher proportions under the different conditions assayed, through very closely followed by that of hydroxybenzoic acids

Flavour in "Pedro Ximénez" grape musts subjected to maceration processes

Crushed grapes of  Vitis vinifera cv. Pedro Ximenez were macerated at 10, 15 and 25°C for 4, 16, 24 and 48 hours. The musts obtained after pressing were used for the determination of higher alcohols, esters and terpene compounds. The data was subjected to discriminant analysis, obtaining three functions of difficult interpretation. A fruitiness index (SIGMA favourable aromas/SIGMA unfavourable aromas) x 100 and the total of phenolic compounds were subjected to variance and multiple range analyses which revealed significant differences (p<0.01) for maceration times and temperatures. Taking into account the fruitiness index and phenolic compound values, as well as the significant differences obtained by multifactorial (time-temperature) variance analysis, the 24 h-10°C, 4 h-15°C, 16 h-15°C and 24 h-15°C were the best condition

Simple Sequence Repeats and Mucoid Conversion: Biased mucA Mutagenesis in Mismatch Repair-Deficient Pseudomonas aeruginosa

In Pseudomonas aeruginosa, conversion to the mucoid phenotype marks the onset of an irreversible state of the infection in Cystic Fibrosis (CF) patients. The main pathway for mucoid conversion is mutagenesis of the mucA gene, frequently due to −1 bp deletions in a simple sequence repeat (SSR) of 5 Gs (G5-SSR426). We have recently observed that this mucA mutation is particularly accentuated in Mismatch Repair System (MRS)-deficient cells grown in vitro. Interestingly, previous reports have shown a high prevalence of hypermutable MRS-deficient strains occurring naturally in CF chronic lung infections. Here, we used mucA as a forward mutation model to systematically evaluate the role of G5-SSR426 in conversion to mucoidy in a MRS-deficient background, with this being the first analysis combining SSR-dependent localized hypermutability and the acquisition of a particular virulence/persistence trait in P. aeruginosa. In this study, mucA alleles were engineered with different contents of G:C SSRs, and tested for their effect on the mucoid conversion frequency and mucA mutational spectra in a mutS-deficient strain of P. aeruginosa. Importantly, deletion of G5-SSR426 severely reduced the emergence frequency of mucoid variants, with no preferential site of mutagenesis within mucA. Moreover, although mutagenesis in mucA was not totally removed, this was no longer the main pathway for mucoid conversion, suggesting that G5-SSR426 biased mutations towards mucA. Mutagenesis in mucA was restored by the addition of a new SSR (C6-SSR431), and even synergistically increased when G5-SSR426 and C6-SSR431 were present simultaneously, with the mucA mutations being restricted to −1 bp deletions within any of both G:C SSRs. These results confirm a critical role for G5-SSR426 enhancing the mutagenic process of mucA in MRS-deficient cells, and shed light on another mechanism, the SSR- localized hypermutability, contributing to mucoid conversion in P. aeruginosa