Inclusão parcial e total de raspa de mandioca na porção energética de rações para caprinos.

A utilização de culturas adaptadas ou nativas ao semi-árido, como a silagem de maniçoba, a raspa de mandioca e o sorgo na alimentação animal poderia reduzir a deficiência alimentar dos rebanhos, elevar os índices de produtividade e conferir competitividade aos sistemas de produção animal. O bjetivo do presente estudo foi avaliar o desempenho de caprinos em crescimento alimentados com rações contendo silagem de Maniçoba e inclusões parciais e total de raspa de mandioca na porção energética do concentrado, usando a proporção de 80% de volumoso e 20% de concentrado, na matéria seca. Os tratamentos avaliados foram: raspa de mandioca, raspa de mandioca em associação com farelo de trigo e raspa de mandioca associada ao sorgo em grãos. Foram utilizados 18 caprinos machos com peso vivo inicial médio de 14,06±3,61 kg distribuídos em três grupos, mantidos em baias coletivas, cada baia com seis animais. O delineamento experimental adotado foi o inteiramente casualizado com seis repetições. Não foram observadas diferenças significativas (P>0,05) entre os tratamentos avaliados sobre os pesos vivos iniciais e finais, ganhos médios diários, ganhos de peso totais e escores de condição corporal inicial e final. As inclusões parciais e total da raspa de mandioca em rações para caprinos em crescimento alimentados com silagem de maniçoba foram tecnicamente viáveis. A opção de uso ficará por conta das vantagens econômicas de cada uma das estratégias avaliadas

Avaliação das cultivares brasileiras de arroz irrigado em várzeas do Estado de Goiás.

A EMATER-GO em parceria com a Embrapa Arroz e Feijão, teve a iniciativa de avaliar o conjunto de cultivares em utilização pelos produtores, a fim de identificar as melhores opções para as várzeas do Estado de Goiás

Design, Fabrication and Characterization

Funding Information: This work was financed by national funds from FCT, Fundação para a Ciência e a Tecnologia, I.P., in the scope of the projects LA/P/0037/2020, UIDP/50025/2020, and UIDB/50025/2020 of the Associate Laboratory Institute of Nanostructures, Nanomodelling and Nanofabrication, i3N, and also under project dPCR4FreeDNA of the same research unit, PTDC/BTM-SAL/31201/2017. Furthermore, the work received funding from FCT in the scope of projects UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences, UCIBIO, and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy, i4HB. B. J. Coelho acknowledges FCT for the attribution of grant SFRH/BD/132904/2017 and grant COVID/BD/152453/2022. Publisher Copyright: © 2023 by the authors.Microfluidic-based platforms have become a hallmark for chemical and biological assays, empowering micro- and nano-reaction vessels. The fusion of microfluidic technologies (digital microfluidics, continuous-flow microfluidics, and droplet microfluidics, just to name a few) presents great potential for overcoming the inherent limitations of each approach, while also elevating their respective strengths. This work exploits the combination of digital microfluidics (DMF) and droplet microfluidics (DrMF) on a single substrate, where DMF enables droplet mixing and further acts as a controlled liquid supplier for a high-throughput nano-liter droplet generator. Droplet generation is performed at a flow-focusing region, operating on dual pressure: negative pressure applied to the aqueous phase and positive pressure applied to the oil phase. We evaluate the droplets produced with our hybrid DMF–DrMF devices in terms of droplet volume, speed, and production frequency and further compare them with standalone DrMF devices. Both types of devices enable customizable droplet production (various volumes and circulation speeds), yet hybrid DMF–DrMF devices yield more controlled droplet production while achieving throughputs that are similar to standalone DrMF devices. These hybrid devices enable the production of up to four droplets per second, which reach a maximum circulation speed close to 1540 µm/s and volumes as low as 0.5 nL.publishersversionpublishe

Impact of MELD allocation policy on survival outcomes after liver transplantation: a single-center study in northeast Brazil

OBJECTIVE: To analyze the impact of model for end-stage liver disease (MELD) allocation policy on survival outcomes after liver transplantation (LT). INTRODUCTION: Considering that an ideal system of grafts allocation should also ensure improved survival after transplantation, changes in allocation policies need to be evaluated in different contexts as an evolutionary process. METHODS: A retrospective cohort study was carried out among patients who underwent LT at the University of Pernambuco. Two groups of patients transplanted before and after the MELD allocation policy implementation were identified and compared using early postoperative mortality and post-LT survival as end-points. RESULTS: Overall, early postoperative mortality did not significantly differ between cohorts (16.43% vs. 8.14%; p = 0.112). Although at 6 and 36-months the difference between pre-vs. post-MELD survival was only marginally significant (p = 0.066 and p = 0.063; respectively), better short, medium and long-term post-LT survival were observed in the post-MELD period. Subgroups analysis showed special benefits to patients categorized as nonhepatocellular carcinoma (non-HCC) and moderate risk, as determined by MELD score (15-20). DISCUSSION: This study ensured a more robust estimate of how the MELD policy affected post-LT survival outcomes in Brazil and was the first to show significantly better survival after this new policy was implemented. Additionally, we explored some potential reasons for our divergent survival outcomes. CONCLUSION: Better survival outcomes were observed in this study after implementation of the MELD criterion, particularly amongst patients categorized as non-HCC and moderate risk by MELD scoring. Governmental involvement in organ transplantation was possibly the main reason for improved survival

Parâmetros estruturais da erva-sal cultivada em diferentes espaçamentos e irrigada com rejeito de dessalinizadores no semi-árido.

O objetivo do presente estudo foi avaliar os efeitos de diferentes espaçamentos sobre os parâmetros estruturais da erva-sal irrigada com rejeito de dessalinizadores

BRSMG Alterosa: cultivar de arroz para plantio em várzeas mineiras.

O processo de indicação de cultivares de arroz para plantios comerciais é contínuo e dinâmico, periodicamente recomendam-se novas cultivares em substituição àquelas menos produtivas e/ou com menor aceitação comercial. É dentro desta linha de ação que a EPAMIG e a Embrapa Arroz e Feijão, por meio do Programa de Melhoramento Genético de Arroz Irrigado, testa a cada ano diversas linhagens e cultivares, em diferentes locais de Minas Gerais, visando oferecer as melhores opções aos orizicultores, no que tange à escolha de cultivares apropriadas às suas lavouras cultivadas em várzeas

COPD: can genetic Background inform about disease heterogeneity?

People with COPD vary substantially on their pulmonary (e.g., airway obstruction) and extra-pulmonary (e.g., symptoms, functional status) manifestations. The aim of this study was to relate this high heterogeneity to the patient’s genetic Background, namely focusing on polymorphisms associated with COPD and COPD-associated phenotypes and features. Summary statistics for COPD and COPD-associated phenotypes and features (emphysema, FEV1, FEV1/FVC, smoking, BMI, asthma, airway responsiveness, coronary heart disease, blood pressure, pulmonary artery enlargement, resting heart rate and resting oxygen saturation) were obtained from GWAS Catalog (https://www.ebi.ac.uk/gwas/ accessed in August 2021). A local COPD cohort was genotyped using Global Screening Arrays (GSA-Illumina) and polygenic risk scores were calculated per phenotype/feature. A cluster analysis was then carried out to determine how patients would group according to their assessed genetic risks. The study currently includes 255 participants with COPD (68 [61, 74] years old; 79.61% male; FEV1/FVC 53.02 [41.24, 61.94]). Our preliminary results show that people cluster into 3 main groups based on their genetic risk for emphysema, followed by COPD, whilst their clinical characteristics remained similar among groups. Future work is currently being conducted to further explore these clusters and perform their validation. This work was funded by FEDER funds through COMPETE 2020, Operational Programme for Competitiveness and Internationalization (POCI-01-0145-FEDER-028806), CENTRO 2020 (CENTRO-01-0246-FEDER-000018; CENTRO-08-5864-FSE-000039) and by Fundação para a Ciência e a Tecnologia (UI/BD/151337/2021). The iBiMED is supported by FCT funds under UIDP/04501/2020.publishe

Conversão de cultivares de arroz para tolerância ao herbicida do grupo das Imidazolinonas utilizando o mutante 93AS3510 : relatório técnico.

O objetivo do trabalho foi incorporar nas cultivares de arroz irrigado BRS Taim e BRS Pelota o alelo que confere tolerância ao herbicida da classe das imidazolinonas presente na linhagem mutante 93AS3510, através de retrocruzamentos.bitstream/CNPAF-2009-09/28186/1/doc_231.pd

Efeito da estação de monta e do tipo de cruzamento sobre o desempenho de cabras na regiao semi-arida do Nordeste do Brasil.

O objetivo desse trabalho foi avaliar o efeito da estação de monta e do tipo de cruzamento sobre o desempenho produtivo e reprodutivo de cabras criadas em sistema de produção agroecológico, na região semi-árida do Nordeste do Brasil