226 research outputs found

    Recent developments in scholarly publishing to improve research practices in the life sciences

    Get PDF
    This is the author accepted manuscript. The final version is available from Portland Press via the DOI in this record.We outline recent developments in scholarly publishing that we think will improve the working environment and career prospects for life scientists. Most prominently, we discuss two key developments. (1) Life scientists are now embracing a preprint culture leading to rapid dissemination of research findings. (2) We outline steps to overcome the reproducibility crisis. We also briefly describe other innovations in scholarly publishing, along with changes to open access mandates from funding agencies.John Templeton Foundatio

    Clinical implications of increased testing in primary care

    Get PDF
    This is the final version. Available from BMJ Publishing Group via the DOI in this recor

    Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study

    Get PDF
    We compared the distribution by wealth of self-reported illness burden (estimated from validated scales, biomarker and reported symptoms) for angina, cataract, depression, diabetes and osteoarthritis, with the distribution of self-reported medical diagnosis and treatment. We aimed to determine if the greater illness burden borne by poorer participants was matched by appropriately higher levels of diagnosis and treatment

    75^{75}As NMR of Ba(Fe0.93_{0.93}Co0.07_{0.07})2_{2}As2_{2} in High Magnetic Field

    Full text link
    The superconducting state of an optimally doped single crystal of Ba(Fe0.93_{0.93}Co0.07_{0.07})2_2As2_2 was investigated by 75^{75}As NMR in high magnetic fields from 6.4 T to 28 T. It was found that the Knight shift is least affected by vortex supercurrents in high magnetic fields, H>11H>11 T, revealing slow, possibly higher order than linear, increase with temperature at T0.5TcT \lesssim 0.5 \, T_c, with Tc23KT_c \approx 23 \, K. This is consistent with the extended s-wave state with A1gA_{1g} symmetry but the precise details of the gap structure are harder to resolve. Measurements of the NMR spin-spin relaxation time, T2T_2, indicate a strong indirect exchange interaction at all temperatures. Below the superconducting transition temperature vortex dynamics lead to an anomalous dip in T2T_2 at the vortex freezing transition from which we obtain the vortex phase diagram up to H=28H = 28 T.Comment: 13 pages, 9 figure

    Modelling both the continual erosion and regeneration of discolouration material in drinking water distribution systems

    Get PDF
    The erosion of the cohesive layers of particulate matter that causes discolouration in water distribution system mains has previously been modelled using the Prediction of Discolouration in Distribution Systems (PODDS) model. When first proposed, PODDS featured an unvalidated means by which material regeneration on pipe walls could be simulated. Field and laboratory studies of material regeneration have yielded data that suggest that the PODDS formulations incorrectly model these processes. A new model is proposed to overcome this shortcoming. It tracks the relative amount of discolouration material that is bound to the pipe wall over time at each of a number of shear strengths. The model formulations and a mass transport model have been encoded as software, which has been used to verify the model’s constructs and undertake sensitivity analyses. The new formulations for regeneration are conceptually consistent with field and laboratory observed data and has potential value in the proactive management of water distribution systems, such as evaluating change in discolouration risk and planning timely interventions
    corecore