Dichlorido{2-[(thio­phen-2-ylmeth­yl)imino­meth­yl]pyridine-κ2 N,N′}palladium(II)

In the title compound, [PdCl2(C11H10N2S)], the PdII ion is four-coordinated in a distorted square-planar environment by two N atoms of the chelating 2-[(thio­phen-2-ylmeth­yl)imino­meth­yl]pyridine ligand and two chloride anions. The thio­phene ring is rotationally disordered over two orientations in a 1:1 ratio. The crystal packing exhibits weak inter­molecular C—H⋯Cl and C—H⋯S hydrogen bonds

Dichlorido[2-(phenyl­imino­meth­yl)quinoline-N,N′]palladium(II)

In the title complex, [PdCl2(C16H12N2)], the PdII ion is coordinated by two N atoms [Pd—N 2.039 (2), 2.073 (2) Å] from a bidentate ligand and two chloride anions [Pd—Cl 2.2655 (7), 2.2991 (7) Å] in a distorted square-planar geometry. In the crystal, π–π inter­actions between the six-membered rings of the quinoline fragments [centroid–centroid distances = 3.815 (5), 3.824 (5) Å] link two mol­ecules into centrosymmetric dimers

New imino-pyridyl nickel (II) complexes: synthesis, molecular structures and application as Heck coupling catalysts

Reactions of imino-pyridyl ligands, (2-pyridyl-2-thiophenemethyl)imine (L1) and (2-pyridyl-2-thiopheneethyl)imine (L2) with NiBr2(DME) gave the corresponding complexes [Ni(L1)Br2] (1) and [Ni(L2)Br2] (2) in good yields. Treatment of 1 and 2 with one equivalent of 2-hydroxythiophenol resulted in the displacement of the bromide ligands to form the nickel(II) thiolato complexes 3 and 4. Molecular structure of 3 confirmed that L1 and L2 bind to the nickel atom in a bidentate fashion. Complexes 1-4 catalyzed the Heck coupling reaction of iodobenzene and bromobenzene with methyl acrylate.Web of Scienc

Dichlorido-[2-(2,6-diethylphenyl)iminomethylquinoline-N,N’]palladium(II) acetonitrile monosolvate

The title complex, [PdCl2(C20H20N2)] CH3CN, was synthesized by the reaction of 2-[(2,6-diethylphenyl)iminomethyl]quinoline with dichlorido(cycloocta-1,5-diene)palladium(II) in dry CH2Cl2. The PdII ion is coordinated by two N atoms of the bidentate quinoline ligand and by two chloride anions, generating a distorted square-planar coordination geometry around the metal centre. There is a detectable trans influence for the chloride ligands. The crystal packing is characterized by – stacking between the quinoline rings. The use of acetonitrile as the crystallization solvent was essential for obtaining good-quality crystals.Web of Scienc

Chlorido[2-({[2-(diphenyl­phosphan­yl)­benzyl­idene]amino}­meth­yl)thio­phene-κ2 N,P]methyl­palladium(II)

In the title compound, [Pd(CH3)Cl(C24H20NPS)], the PdII ion is coordinated in a distorted square-planar environment which includes the P and N atoms of the bis-chelating ligand. The thio­phene ring is rotationally ordered, unlike in the majority of crystal structures containing this group

Imino-quinolyl palladium(II) and platinum(II) complexes: synthesis, characterization, molecular structures and cytotoxic effect

Imino-quinolyl ligands L1-L5 were synthesized by condensation reactions and obtained in good yields. Reactions of the ligands with either PdCl2(cod) or K2[PtCl4] gave the corresponding palladium(II) and platinum(II) complexes 1-10 also in good yields. All the compounds were characterized by elemental analysis, IR, 1H and 13C NMR spectroscopy. X-ray crystallography was used to confirm the structures of these compounds. Molecular structures of 3 and 5 showed that the ligands coordinate to the metal centre through the two nitrogen atoms, generating a distorted square planar geometry around the palladium atom. The new complexes exhibited remarkable cytotoxic activities against MCF-7 and HT-29 cancer cell lines.Web of Scienc

Chlorido{N-[2-(diphenylphosphanyl)- benzylidene]-2-(2-thienyl)ethanamine-ĸ²N,P}methylpalladium(II) dichloromethane hemisolvate

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Quinoline-2-carbaldehyde

The title compound, C10H7NO, crystallizes with two almost planar mol­ecules (A and B) in the asymmetric unit (r.m.s. deviations = 0.018 and 0.020 Å). In the crystal, the A mol­ecules are linked by weak C—H⋯O inter­actions, thereby generating C(9) [001] chains. The B mol­ecules do not exhibit any directional bonding inter­actions

Chlorido{N-[2-(diphenylphosphanyl)benz­ylidene]-2-(2-thienyl)ethanamine-κ2 N,P}methylpalladium(II) dichloromethane hemisolvate

In the title compound, [Pd(CH3)Cl(C25H22NPS)]·0.5C2H2Cl2, the PdII atom is coordinated by the N,P-bidentate ligand, a methyl group and a chloride ion, generating a distorted square-planar PdCClNS coordination geometry, with the N and Cl atoms trans. The thio­phene ring is equally disordered over two orientations and the dichloro­methane solvent mol­ecule is disordered about an inversion centre

Imino-phospine palladium (II) and platinum (II) complexes: Synthesis, molecular structures and evaluation as antitumor agents

The imino-phosphine ligands L1 and L2 were prepared via condensation reaction of 2-(diphenylphosphino) benzaldehyde with substituted anilines and obtained in very good yields. An equimolar reaction of L1 and L2 with either PdCl2(cod) or PtCl2(cod) gave new palladium(II) and platinum(II) complexes 1–4. The compounds were characterized by elemental analysis, IR, 1H and 31P NMR spectroscopy. The molecular structures of 2, 3 and 4 were confirmed by X-ray crystallography. All the three molecular structures crystallized in monoclinic C2/c space system. The coordination geometry around the palladiumand platinumatoms in respective structures exhibited distorted square planar geometry at the metal centers. The complexes were evaluated in vitro for their cytotoxic activity against human breast (MCF-7) and human colon (HT-29) cancer cells, and they exhibited growth inhibitory activities and selectivity that were superior to the standard compound cisplatin.Web of Scienc